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PDB: 70 results

8FTO
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E. coli 70S ribosome with an improved MS2 tag inserted in H98
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Nissley, A.J, Cate, J.H.D.
Deposit date:2023-01-12
Release date:2023-08-02
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (1.85 Å)
Cite:Interactions between terminal ribosomal RNA helices stabilize the E. coli large ribosomal subunit.
Rna, 29, 2023
8G6W
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Structure of WT E.coli 70S ribosome complexed with mRNA, P-site fMet-NH-tRNAfMet and A-site ortho-aminobenzoic acid charged NH-tRNAPhe
Descriptor: 16S rRNA, 2-AMINO-BENZAMIDE, 23S rRNA, ...
Authors:Majumdar, C, Cate, J.H.D.
Deposit date:2023-02-16
Release date:2023-04-05
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (2.02 Å)
Cite:Aminobenzoic Acid Derivatives Obstruct Induced Fit in the Catalytic Center of the Ribosome.
Acs Cent.Sci., 9, 2023
8EMM
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Composite 70S ribosome structure for "Atomistic simulations of the E. coli ribosome provide selection criteria for translationally active substrates
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Watson, Z.L, Cate, J.H.D.
Deposit date:2022-09-28
Release date:2023-05-31
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (2.1 Å)
Cite:Atomistic simulations of the Escherichia coli ribosome provide selection criteria for translationally active substrates.
Nat.Chem., 15, 2023
8EIU
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E. coli 70S ribosome with A-loop mutations U2554C and U2555C
Descriptor: 16S rRNA, 23S rRNA, 3'-amino-3'-deoxyadenosine 5'-(dihydrogen phosphate), ...
Authors:Nissley, A.J, Penev, P.I, Watson, Z.L, Banfield, J.F, Cate, J.H.D.
Deposit date:2022-09-15
Release date:2023-02-01
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (2.24 Å)
Cite:Rare ribosomal RNA sequences from archaea stabilize the bacterial ribosome.
Nucleic Acids Res., 51, 2023
7PJS
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Structure of the 70S ribosome with tRNAs in the classical pre-translocation state and apramycin (C)
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Petrychenko, V, Peng, B.Z, Schwarzer, A.C, Peske, F, Rodnina, M.V, Fischer, N.
Deposit date:2021-08-24
Release date:2021-10-20
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (2.35 Å)
Cite:Structural mechanism of GTPase-powered ribosome-tRNA movement
Nat Commun, 12, 2021
6YSS
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Structure of the P+9 ArfB-ribosome complex in the post-hydrolysis state
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Chan, K.-H, Petrychenko, V, Mueller, C, Maracci, C, Holtkamp, W, Wilson, D.N, Fischer, N, Rodnina, M.V.
Deposit date:2020-04-23
Release date:2020-08-19
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Mechanism of ribosome rescue by alternative ribosome-rescue factor B.
Nat Commun, 11, 2020
7NWT
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Initiated 70S ribosome in complex with 2A protein from encephalomyocarditis virus (EMCV)
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Hill, C.H, Napthine, S, Pekarek, L, Kibe, A, Firth, A.E, Graham, S.C, Caliskan, N, Brierley, I.
Deposit date:2021-03-17
Release date:2021-12-15
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (2.66 Å)
Cite:Structural and molecular basis for Cardiovirus 2A protein as a viral gene expression switch
Nat Commun, 12, 2021
8EKC
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Escherichia coli 70S ribosome bound to thermorubin, deacylated P-site tRNAfMet and aminoacylated A-site Phe-tRNA
Descriptor: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Rybak, M.Y, Gagnon, M.G.
Deposit date:2022-09-20
Release date:2022-12-07
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Insights into the molecular mechanism of translation inhibition by the ribosome-targeting antibiotic thermorubin.
Nucleic Acids Res., 51, 2023
8G7R
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Structure of the Escherichia coli 70S ribosome in complex with A-site tRNAIle(LAU) bound to the cognate AUA codon (Structure III)
Descriptor: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Rybak, M.Y, Gagnon, M.G.
Deposit date:2023-02-16
Release date:2024-03-06
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Structures of the ribosome bound to EF-Tu-isoleucine tRNA elucidate the mechanism of AUG avoidance.
Nat.Struct.Mol.Biol., 31, 2024
8EYT
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30S_delta_ksgA+KsgA complex
Descriptor: 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
Authors:Sun, J, Kinman, L.F, Jahagirdar, D, Ortega, J, Davis, J.H.
Deposit date:2022-10-28
Release date:2023-09-06
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:KsgA facilitates ribosomal small subunit maturation by proofreading a key structural lesion.
Nat.Struct.Mol.Biol., 30, 2023
8FZH
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BU of 8fzh by Molmil
Cryo-EM structure of an E. coli non-rotated ribosome termination complex bound with RF1, P- and E-site tRNAPhe (State II-D)
Descriptor: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Rybak, M.Y, Li, L, Lin, J, Gagnon, M.G.
Deposit date:2023-01-28
Release date:2024-07-17
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:The ribosome termination complex remodels release factor RF3 and ejects GDP
Nat.Struct.Mol.Biol., 2024
8SYL
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Cryo-EM structure of the Escherichia coli 70S ribosome in complex with amikacin, mRNA, and A-, P-, and E-site tRNAs
Descriptor: (2S)-N-[(1R,2S,3S,4R,5S)-4-[(2R,3R,4S,5S,6R)-6-(aminomethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]oxy-5-azanyl-2-[(2S,3R,4S,5S ,6R)-4-azanyl-6-(hydroxymethyl)-3,5-bis(oxidanyl)oxan-2-yl]oxy-3-oxidanyl-cyclohexyl]-4-azanyl-2-oxidanyl-butanamide, 16S Ribosomal RNA, 23S Ribosomal RNA, ...
Authors:Seely, S.M, Gagnon, M.G.
Deposit date:2023-05-25
Release date:2023-08-09
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Molecular basis of the pleiotropic effects by the antibiotic amikacin on the ribosome.
Nat Commun, 14, 2023
7OT5
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BU of 7ot5 by Molmil
CspA-70 cotranslational folding intermediate 1
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Agirrezabala, X, Samatova, E, Macher, M, Liutkute, M, Gil-Carton, D, Novacek, J, Valle, M, Rodnina, M.V.
Deposit date:2021-06-09
Release date:2022-01-19
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:A switch from alpha-helical to beta-strand conformation during co-translational protein folding.
Embo J., 41, 2022
7NSO
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BU of 7nso by Molmil
Structure of ErmDL-Erythromycin-stalled 70S E. coli ribosomal complex with P-tRNA
Descriptor: 16S rRNA (1540-MER), 23S rRNA (2903-MER), 30S ribosomal protein S10, ...
Authors:Beckert, B, Wilson, D.N.
Deposit date:2021-03-08
Release date:2021-07-14
Last modified:2021-08-11
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structural and mechanistic basis for translation inhibition by macrolide and ketolide antibiotics.
Nat Commun, 12, 2021
8G7P
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BU of 8g7p by Molmil
Structure of the Escherichia coli 70S ribosome in complex with EF-Tu and Ile-tRNAIle(LAU) bound to the cognate AUA codon (Structure I)
Descriptor: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Rybak, M.Y, Gagnon, M.G.
Deposit date:2023-02-16
Release date:2024-03-06
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structures of the ribosome bound to EF-Tu-isoleucine tRNA elucidate the mechanism of AUG avoidance.
Nat.Struct.Mol.Biol., 31, 2024
7NAX
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BU of 7nax by Molmil
Complete Bacterial 30S ribosomal subunit assembly complex state I (Consensus Refinement)
Descriptor: 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
Authors:Schedlbauer, A, Iturrioz, I, Ochoa-Lizarralde, B, Diercks, T, Lopez-Alonso, J, Kaminishi, T, Capuni, R, Astigarraga, E, Gil-Carton, D, Fucini, P, Connell, S.
Deposit date:2021-01-25
Release date:2021-12-08
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (2.96 Å)
Cite:A conserved rRNA switch is central to decoding site maturation on the small ribosomal subunit.
Sci Adv, 7, 2021
8GHU
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BU of 8ghu by Molmil
Methyltransferase RmtC bound to the 30S ribosomal subunit
Descriptor: 16S rRNA, 16S rRNA (guanine(1405)-N(7))-methyltransferase, 30S ribosomal protein S12, ...
Authors:Srinivas, P, Conn, G.L, Dunham, C.M.
Deposit date:2023-03-12
Release date:2023-04-12
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (3 Å)
Cite:30S subunit recognition and G1405 modification by the aminoglycoside-resistance 16S ribosomal RNA methyltransferase RmtC.
Biorxiv, 2023
7Q4K
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BU of 7q4k by Molmil
Erythromycin-stalled Escherichia coli 70S ribosome with streptococcal MsrDL nascent chain
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Fostier, C.R, Ousalem, F, Soufari, H, Leroy, E.C, Ngo, S, Innis, A, Hashem, Y, Boel, G.
Deposit date:2021-10-31
Release date:2022-11-16
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Regulation of the macrolide resistance ABC-F translation factor MsrD.
Nat Commun, 14, 2023
7OIF
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BU of 7oif by Molmil
CspA-27 cotranslational folding intermediate 2
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Agirrezabala, X, Samatova, E, Macher, M, Liutkute, M, Gil-Carton, D, Novacek, J, Valle, M, Rodnina, M.V.
Deposit date:2021-05-11
Release date:2022-01-19
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (3 Å)
Cite:A switch from alpha-helical to beta-strand conformation during co-translational protein folding.
Embo J., 41, 2022
7OII
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BU of 7oii by Molmil
CspA-70 cotranslational folding intermediate 2
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Agirrezabala, X, Samatova, E, Macher, M, Liutkute, M, Gil-Carton, D, Novacek, J, Valle, M, Rodnina, M.V.
Deposit date:2021-05-11
Release date:2022-01-19
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (3 Å)
Cite:A switch from alpha-helical to beta-strand conformation during co-translational protein folding.
Embo J., 41, 2022
8FZJ
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BU of 8fzj by Molmil
Cryo-EM structure of an E. coli rotated ribosome bound with RF3-GDPCP and p/E-tRNAPhe (Composite state II-C)
Descriptor: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Rybak, M.Y, Li, L, Lin, J, Gagnon, M.G.
Deposit date:2023-01-28
Release date:2024-07-17
Method:ELECTRON MICROSCOPY (3 Å)
Cite:The ribosome termination complex remodels release factor RF3 and ejects GDP
Nat.Struct.Mol.Biol., 2024
8FZE
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BU of 8fze by Molmil
Cryo-EM structure of an E. coli non-rotated ribosome termination complex bound with RF1, P- and E-site tRNAPhe (State I-A)
Descriptor: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Rybak, M.Y, Li, L, Lin, J, Gagnon, M.G.
Deposit date:2023-01-28
Release date:2024-07-17
Method:ELECTRON MICROSCOPY (3 Å)
Cite:The ribosome termination complex remodels release factor RF3 and ejects GDP
Nat.Struct.Mol.Biol., 2024
6ZTP
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E. coli 70S-RNAP expressome complex in uncoupled state 6
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Webster, M.W, Takacs, M, Weixlbaumer, A.
Deposit date:2020-07-20
Release date:2020-09-16
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structural basis of transcription-translation coupling and collision in bacteria.
Science, 369, 2020
8G2U
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BU of 8g2u by Molmil
Time-resolved cryo-EM study of the 70S recycling by the HflX:control-apo-70S at 900ms
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Bhattacharjee, S, Brown, P.Z, Frank, J.
Deposit date:2023-02-06
Release date:2023-12-06
Last modified:2024-02-14
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Time resolution in cryo-EM using a PDMS-based microfluidic chip assembly and its application to the study of HflX-mediated ribosome recycling.
Cell, 187, 2024
6ZTO
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BU of 6zto by Molmil
E. coli 70S-RNAP expressome complex in uncoupled state 1
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Webster, M.W, Takacs, M, Weixlbaumer, A.
Deposit date:2020-07-20
Release date:2020-09-23
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structural basis of transcription-translation coupling and collision in bacteria.
Science, 369, 2020

 

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