7K53
| Pre-translocation +1-frameshifting(CCC-A) complex (Structure I-FS) | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Demo, G, Loveland, A.B, Svidritskiy, E, Gamper, H.B, Hou, Y.M, Korostelev, A.A. | Deposit date: | 2020-09-16 | Release date: | 2021-07-28 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structural basis for +1 ribosomal frameshifting during EF-G-catalyzed translocation. Nat Commun, 12, 2021
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8G38
| Time-resolved cryo-EM study of the 70S recycling by the HflX:3rd Intermediate | Descriptor: | 16S, 23S, 30S ribosomal protein S10, ... | Authors: | Bhattacharjee, S, Brown, P.Z, Frank, J. | Deposit date: | 2023-02-07 | Release date: | 2023-12-06 | Last modified: | 2024-02-14 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Time resolution in cryo-EM using a PDMS-based microfluidic chip assembly and its application to the study of HflX-mediated ribosome recycling. Cell, 187, 2024
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8G31
| Time-resolved cryo-EM study of the 70S recycling by the HflX:2nd Intermediate | Descriptor: | 16S, 23S, 30S ribosomal protein S10, ... | Authors: | Bhattacharjee, S, Brown, P.Z, Frank, J. | Deposit date: | 2023-02-06 | Release date: | 2023-12-06 | Last modified: | 2024-02-14 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Time resolution in cryo-EM using a PDMS-based microfluidic chip assembly and its application to the study of HflX-mediated ribosome recycling. Cell, 187, 2024
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8G34
| Time-resolved cryo-EM study of the 70S recycling by the HflX:1st intermediate | Descriptor: | 16S, 23S, 30S ribosomal protein S10, ... | Authors: | Bhattacharjee, S, Brown, P.Z, Frank, J. | Deposit date: | 2023-02-06 | Release date: | 2023-12-06 | Last modified: | 2024-02-14 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Time resolution in cryo-EM using a PDMS-based microfluidic chip assembly and its application to the study of HflX-mediated ribosome recycling. Cell, 187, 2024
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6WDD
| Cryo-EM of elongating ribosome with EF-Tu*GTP elucidates tRNA proofreading (Cognate Structure V-A) | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Loveland, A.B, Demo, G, Korostelev, A.A. | Deposit date: | 2020-03-31 | Release date: | 2020-07-01 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Cryo-EM of elongating ribosome with EF-Tu•GTP elucidates tRNA proofreading. Nature, 584, 2020
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7K54
| Mid-translocated +1-frameshifting(CCC-A) complex with EF-G and GDPCP (Structure II-FS) | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Demo, G, Loveland, A.B, Svidritskiy, E, Gamper, H.B, Hou, Y.M, Korostelev, A.A. | Deposit date: | 2020-09-16 | Release date: | 2021-07-28 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structural basis for +1 ribosomal frameshifting during EF-G-catalyzed translocation. Nat Commun, 12, 2021
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5U9G
| 3.2 A cryo-EM ArfA-RF2 ribosome rescue complex (Structure I) | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Demo, G, Svidritskiy, E, Madireddy, R, Diaz-Avalos, R, Grant, T, Grigorieff, N, Sousa, D, Korostelev, A.A. | Deposit date: | 2016-12-16 | Release date: | 2017-03-22 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Mechanism of ribosome rescue by ArfA and RF2. Elife, 6, 2017
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5UYM
| 70S ribosome bound with cognate ternary complex base-paired to A site codon, closed 30S (Structure III) | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Loveland, A.B, Demo, G, Grigorieff, N, Korostelev, A.A. | Deposit date: | 2017-02-24 | Release date: | 2017-06-07 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Ensemble cryo-EM elucidates the mechanism of translation fidelity Nature, 546, 2017
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4V52
| Crystal structure of the bacterial ribosome from Escherichia coli in complex with neomycin. | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | Authors: | Borovinskaya, M.A, Pai, R.D, Zhang, W, Schuwirth, B.-S, Holton, J.M, Hirokawa, G, Kaji, H, Kaji, A, Cate, J.H.D. | Deposit date: | 2007-06-15 | Release date: | 2014-07-09 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (3.21 Å) | Cite: | Structural basis for aminoglycoside inhibition of bacterial ribosome recycling. Nat.Struct.Mol.Biol., 14, 2007
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7ABZ
| Structure of pre-accomodated trans-translation complex on E. coli stalled ribosome. | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Guyomar, C, D'Urso, G, Chat, S, Giudice, E, Gillet, R. | Deposit date: | 2020-09-09 | Release date: | 2021-08-18 | Last modified: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (3.21 Å) | Cite: | Structures of tmRNA and SmpB as they transit through the ribosome. Nat Commun, 12, 2021
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4V50
| Crystal Structure of Ribosome with messenger RNA and the Anticodon stem-loop of P-site tRNA. | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Berk, V, Zhang, W, Pai, R.D, Cate, J.H.D. | Deposit date: | 2006-08-16 | Release date: | 2014-07-09 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (3.22 Å) | Cite: | Structural basis for mRNA and tRNA positioning on the ribosome. Proc.Natl.Acad.Sci.Usa, 103, 2006
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6C4I
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4V7S
| Crystal structure of the E. coli ribosome bound to telithromycin. | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | Authors: | Dunkle, J.A, Xiong, L, Mankin, A.S, Cate, J.H.D. | Deposit date: | 2010-08-05 | Release date: | 2014-07-09 | Last modified: | 2024-11-06 | Method: | X-RAY DIFFRACTION (3.2547 Å) | Cite: | Structures of the Escherichia coli ribosome with antibiotics bound near the peptidyl transferase center explain spectra of drug action. Proc.Natl.Acad.Sci.USA, 107, 2010
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8R3V
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4V7V
| Crystal structure of the E. coli ribosome bound to clindamycin. | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | Authors: | Dunkle, J.A, Xiong, L, Mankin, A.S, Cate, J.H.D. | Deposit date: | 2010-08-16 | Release date: | 2014-07-09 | Last modified: | 2024-11-06 | Method: | X-RAY DIFFRACTION (3.2891 Å) | Cite: | Structures of the Escherichia coli ribosome with antibiotics bound near the peptidyl transferase center explain spectra of drug action. Proc.Natl.Acad.Sci.USA, 107, 2010
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6WDF
| Cryo-EM of elongating ribosome with EF-Tu*GTP elucidates tRNA proofreading (Cognate Structure VI-A) | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Loveland, A.B, Demo, G, Korostelev, A.A. | Deposit date: | 2020-03-31 | Release date: | 2020-07-01 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Cryo-EM of elongating ribosome with EF-Tu•GTP elucidates tRNA proofreading. Nature, 584, 2020
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4V9C
| Allosteric control of the ribosome by small-molecule antibiotics | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Cate, J.H.D, Pulk, A, Blanchard, S.C, Wang, L, Feldman, M.B, Wasserman, M.R, Altman, R. | Deposit date: | 2012-07-25 | Release date: | 2014-07-09 | Last modified: | 2024-10-30 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Allosteric control of the ribosome by small-molecule antibiotics. Nat.Struct.Mol.Biol., 19, 2012
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6WDG
| Cryo-EM of elongating ribosome with EF-Tu*GTP elucidates tRNA proofreading (Cognate Structure VI-B) | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Loveland, A.B, Demo, G, Korostelev, A.A. | Deposit date: | 2020-03-31 | Release date: | 2020-07-01 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Cryo-EM of elongating ribosome with EF-Tu•GTP elucidates tRNA proofreading. Nature, 584, 2020
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6WD1
| Cryo-EM of elongating ribosome with EF-Tu*GTP elucidates tRNA proofreading (Cognate Structure I-B) | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Loveland, A.B, Demo, G, Korostelev, A.A. | Deposit date: | 2020-03-31 | Release date: | 2020-07-01 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Cryo-EM of elongating ribosome with EF-Tu•GTP elucidates tRNA proofreading. Nature, 584, 2020
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7SSD
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8PEG
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6OG7
| 70S termination complex with RF2 bound to the UGA codon. Non-rotated ribosome with RF2 bound (Structure II) | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Svidritskiy, E, Demo, G, Loveland, A.B, Xu, C, Korostelev, A.A. | Deposit date: | 2019-04-01 | Release date: | 2019-09-25 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Extensive ribosome and RF2 rearrangements during translation termination. Elife, 8, 2019
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4V54
| Crystal structure of the bacterial ribosome from Escherichia coli in complex with ribosome recycling factor (RRF). | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | Authors: | Borovinskaya, M.A, Pai, R.D, Zhang, W, Schuwirth, B.-S, Holton, J.M, Hirokawa, G, Kaji, H, Kaji, A, Cate, J.H.D. | Deposit date: | 2007-06-16 | Release date: | 2014-07-09 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Structural basis for aminoglycoside inhibition of bacterial ribosome recycling. Nat.Struct.Mol.Biol., 14, 2007
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8T5H
| Cryo-EM studies of the interplay between uS2 ribosomal protein and leaderless mRNA during bacterial translation initiation | Descriptor: | 16S, 23S, 30S ribosomal protein S10, ... | Authors: | Bhattacharjee, S, Gottesman, M.E, Frank, J. | Deposit date: | 2023-06-13 | Release date: | 2024-08-28 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | How Dedicated Ribosomes Translate a Leaderless mRNA. J.Mol.Biol., 436, 2024
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6OFX
| Non-rotated ribosome (Structure I) | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Svidritskiy, E, Demo, G, Loveland, A.B, Xu, C, Korostelev, A.A. | Deposit date: | 2019-04-01 | Release date: | 2019-09-25 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Extensive ribosome and RF2 rearrangements during translation termination. Elife, 8, 2019
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