Cryo-EM of elongating ribosome with EF-Tu*GTP elucidates tRNA proofreading (Cognate Structure VI-A)

This is a large structure.

Summary for 6WDF

EMDB information21634
Descriptor50S ribosomal protein L2, 50S ribosomal protein L3, 50S ribosomal protein L4, ... (59 entities in total)
Functional Keywordsribosome, ef-tu, trna
Biological sourceEscherichia coli (strain K12)
Total number of polymer chains57
Total molecular weight2213220.59
Loveland, A.B.,Demo, G.,Korostelev, A.A. (deposition date: 2020-03-31, release date: 2020-07-01)
Primary citation
Loveland, A.B.,Demo, G.,Korostelev, A.A.
Cryo-EM of elongating ribosome with EF-Tu.GTP elucidates tRNA proofreading
Nature, 2020
DOI: 10.1038/s41586-020-2447-x
MImport into Mendeley
Experimental method

Structure validation

ClashscoreRamachandran outliersSidechain outliersRNA backbone12 1.8% 1.1% 0.67MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all EM structures
Download full validation reportDownload