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PDB: 35 results

8G6W
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BU of 8g6w by Molmil
Structure of WT E.coli 70S ribosome complexed with mRNA, P-site fMet-NH-tRNAfMet and A-site ortho-aminobenzoic acid charged NH-tRNAPhe
Descriptor: 16S rRNA, 2-AMINO-BENZAMIDE, 23S rRNA, ...
Authors:Majumdar, C, Cate, J.H.D.
Deposit date:2023-02-16
Release date:2023-04-05
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (2.02 Å)
Cite:Aminobenzoic Acid Derivatives Obstruct Induced Fit in the Catalytic Center of the Ribosome.
Acs Cent.Sci., 9, 2023
8G6Y
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Structure of WT E.coli ribosome 50S subunit with complexed with mRNA, P-site fMet-NH-tRNAfMet and A-site 3-aminopyridine-4-carboxylic acid charged NH-tRNAPhe
Descriptor: 23S rRNA, 3'-amino-3'-deoxyadenosine 5'-(dihydrogen phosphate), 3-aminopyridine-4-carboxamide, ...
Authors:Majumdar, C, Cate, J.H.D.
Deposit date:2023-02-16
Release date:2023-04-05
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (2.09 Å)
Cite:Aminobenzoic Acid Derivatives Obstruct Induced Fit in the Catalytic Center of the Ribosome.
Acs Cent.Sci., 9, 2023
9CG5
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70S initiation complex (tRNA-fMet M1 + UUG start codon)
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Mattingly, J.M, Nguyen, H.A, Dunham, C.M.
Deposit date:2024-06-28
Release date:2024-09-18
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (2.59 Å)
Cite:Structural analysis of noncanonical translation initiation complexes.
J.Biol.Chem., 300, 2024
9AX8
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70S initiation complex (tRNA-fMet M1, initiation factor 2 + CUG start codon)
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Mattingly, J.M, Nguyen, H.A, Dunham, C.M.
Deposit date:2024-03-06
Release date:2024-09-18
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Structural analysis of noncanonical translation initiation complexes.
J.Biol.Chem., 300, 2024
9CG6
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70S initiation complex (tRNA-fMet M1 + GUG start codon)
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Mattingly, J.M, Nguyen, H.A, Dunham, C.M.
Deposit date:2024-06-28
Release date:2024-09-18
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (2.61 Å)
Cite:Structural analysis of noncanonical translation initiation complexes.
J.Biol.Chem., 300, 2024
9AX7
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BU of 9ax7 by Molmil
70S initiation complex (tRNA-fMet M1 + CUG start codon)
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Mattingly, J.M, Nguyen, H.A, Dunham, C.M.
Deposit date:2024-03-06
Release date:2024-09-18
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (2.63 Å)
Cite:Structural analysis of noncanonical translation initiation complexes.
J.Biol.Chem., 300, 2024
8EKC
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BU of 8ekc by Molmil
Escherichia coli 70S ribosome bound to thermorubin, deacylated P-site tRNAfMet and aminoacylated A-site Phe-tRNA
Descriptor: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Rybak, M.Y, Gagnon, M.G.
Deposit date:2022-09-20
Release date:2022-12-07
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Insights into the molecular mechanism of translation inhibition by the ribosome-targeting antibiotic thermorubin.
Nucleic Acids Res., 51, 2023
9CG7
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BU of 9cg7 by Molmil
70S initiation complex (tRNA-fMet M1 + AUG start codon)
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Mattingly, J.M, Nguyen, H.A, Dunham, C.M.
Deposit date:2024-06-28
Release date:2024-09-18
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (2.75 Å)
Cite:Structural analysis of noncanonical translation initiation complexes.
J.Biol.Chem., 300, 2024
8G7R
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BU of 8g7r by Molmil
Structure of the Escherichia coli 70S ribosome in complex with A-site tRNAIle(LAU) bound to the cognate AUA codon (Structure III)
Descriptor: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Rybak, M.Y, Gagnon, M.G.
Deposit date:2023-02-16
Release date:2024-03-06
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Structures of the ribosome bound to EF-Tu-isoleucine tRNA elucidate the mechanism of AUG avoidance.
Nat.Struct.Mol.Biol., 31, 2024
8SYL
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BU of 8syl by Molmil
Cryo-EM structure of the Escherichia coli 70S ribosome in complex with amikacin, mRNA, and A-, P-, and E-site tRNAs
Descriptor: (2S)-N-[(1R,2S,3S,4R,5S)-4-[(2R,3R,4S,5S,6R)-6-(aminomethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]oxy-5-azanyl-2-[(2S,3R,4S,5S ,6R)-4-azanyl-6-(hydroxymethyl)-3,5-bis(oxidanyl)oxan-2-yl]oxy-3-oxidanyl-cyclohexyl]-4-azanyl-2-oxidanyl-butanamide, 16S Ribosomal RNA, 23S Ribosomal RNA, ...
Authors:Seely, S.M, Gagnon, M.G.
Deposit date:2023-05-25
Release date:2023-08-09
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Molecular basis of the pleiotropic effects by the antibiotic amikacin on the ribosome.
Nat Commun, 14, 2023
8G7P
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BU of 8g7p by Molmil
Structure of the Escherichia coli 70S ribosome in complex with EF-Tu and Ile-tRNAIle(LAU) bound to the cognate AUA codon (Structure I)
Descriptor: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Rybak, M.Y, Gagnon, M.G.
Deposit date:2023-02-16
Release date:2024-03-06
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structures of the ribosome bound to EF-Tu-isoleucine tRNA elucidate the mechanism of AUG avoidance.
Nat.Struct.Mol.Biol., 31, 2024
8FZH
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BU of 8fzh by Molmil
Cryo-EM structure of an E. coli non-rotated ribosome termination complex bound with RF1, P- and E-site tRNAPhe (State II-D)
Descriptor: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Rybak, M.Y, Li, L, Lin, J, Gagnon, M.G.
Deposit date:2023-01-28
Release date:2024-07-17
Last modified:2024-07-31
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:The ribosome termination complex remodels release factor RF3 and ejects GDP.
Nat.Struct.Mol.Biol., 2024
8FZE
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BU of 8fze by Molmil
Cryo-EM structure of an E. coli non-rotated ribosome termination complex bound with RF1, P- and E-site tRNAPhe (State I-A)
Descriptor: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Rybak, M.Y, Li, L, Lin, J, Gagnon, M.G.
Deposit date:2023-01-28
Release date:2024-07-17
Last modified:2024-07-31
Method:ELECTRON MICROSCOPY (3 Å)
Cite:The ribosome termination complex remodels release factor RF3 and ejects GDP.
Nat.Struct.Mol.Biol., 2024
8FZJ
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BU of 8fzj by Molmil
Cryo-EM structure of an E. coli rotated ribosome bound with RF3-GDPCP and p/E-tRNAPhe (Composite state II-C)
Descriptor: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Rybak, M.Y, Li, L, Lin, J, Gagnon, M.G.
Deposit date:2023-01-28
Release date:2024-07-17
Last modified:2024-07-31
Method:ELECTRON MICROSCOPY (3 Å)
Cite:The ribosome termination complex remodels release factor RF3 and ejects GDP.
Nat.Struct.Mol.Biol., 2024
8G7S
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BU of 8g7s by Molmil
Structure of the Escherichia coli 70S ribosome in complex with P-site tRNAIle(LAU) bound to the cognate AUA codon (Structure IV)
Descriptor: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Rybak, M.Y, Gagnon, M.G.
Deposit date:2023-02-16
Release date:2024-03-06
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structures of the ribosome bound to EF-Tu-isoleucine tRNA elucidate the mechanism of AUG avoidance.
Nat.Struct.Mol.Biol., 31, 2024
8FZI
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BU of 8fzi by Molmil
Cryo-EM structure of an E. coli rotated ribosome bound with RF3-GDPCP and p/E-tRNAPhe (Composite state II-B)
Descriptor: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Rybak, M.Y, Li, L, Lin, J, Gagnon, M.G.
Deposit date:2023-01-28
Release date:2024-07-17
Last modified:2024-07-31
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:The ribosome termination complex remodels release factor RF3 and ejects GDP.
Nat.Struct.Mol.Biol., 2024
8FZD
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BU of 8fzd by Molmil
Cryo-EM structure of an E. coli non-rotated ribosome termination complex bound with apoRF3, RF1, P- and E-site tRNAPhe (Composite state I-B)
Descriptor: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Rybak, M.Y, Li, L, Lin, J, Gagnon, M.G.
Deposit date:2023-01-28
Release date:2024-07-17
Last modified:2024-07-31
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:The ribosome termination complex remodels release factor RF3 and ejects GDP.
Nat.Struct.Mol.Biol., 2024
8FZG
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BU of 8fzg by Molmil
Cryo-EM structure of an E. coli non-rotated ribosome termination complex bound with RF3-GDPCP, RF1, P- and E-site tRNAPhe (Composite state II-A)
Descriptor: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Rybak, M.Y, Li, L, Lin, J, Gagnon, M.G.
Deposit date:2023-01-28
Release date:2024-07-17
Last modified:2024-08-07
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:The ribosome termination complex remodels release factor RF3 and ejects GDP.
Nat.Struct.Mol.Biol., 2024
8URY
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BU of 8ury by Molmil
Escherichia coli transcription-translation coupled complex class B (TTC-B) containing RfaH bound to ops signal, NusA, mRNA with a 30 nt long spacer, and fMet-tRNA in E-site and P-site of the ribosome
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S11, ...
Authors:Molodtsov, V, Wang, C, Ebright, R.H.
Deposit date:2023-10-27
Release date:2024-06-12
Last modified:2024-10-30
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural basis of RfaH-mediated transcription-translation coupling.
Nat.Struct.Mol.Biol., 2024
8G7Q
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BU of 8g7q by Molmil
Structure of the Escherichia coli 70S ribosome in complex with EF-Tu and Ile-tRNAIle(LAU) bound to the near-cognate AUG codon (Structure II)
Descriptor: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Rybak, M.Y, Gagnon, M.G.
Deposit date:2023-02-16
Release date:2024-03-06
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structures of the ribosome bound to EF-Tu-isoleucine tRNA elucidate the mechanism of AUG avoidance.
Nat.Struct.Mol.Biol., 31, 2024
8T5D
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BU of 8t5d by Molmil
Cryo-EM studies of the interplay between uS2 ribosomal protein and leaderless mRNA during bacterial translation initiation
Descriptor: 16s RNA, 23S RNA, 30S ribosomal protein S10, ...
Authors:Bhattacharjee, S, Gottesman, M.E, Frank, J.
Deposit date:2023-06-13
Release date:2024-08-28
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:How Dedicated Ribosomes Translate a Leaderless mRNA.
J.Mol.Biol., 436, 2024
8UQL
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BU of 8uql by Molmil
Escherichia coli transcription-translation coupled complex class B (TTC-B) containing RfaH in loaded state, mRNA with a 24 nt long spacer, and fMet-tRNAs in E-site and P-site of the ribosome
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S1, ...
Authors:Molodtsov, V, Wang, C, Ebright, R.H.
Deposit date:2023-10-24
Release date:2024-05-29
Last modified:2024-08-28
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structural basis of RfaH-mediated transcription-translation coupling.
Nat.Struct.Mol.Biol., 2024
8FZF
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BU of 8fzf by Molmil
Cryo-EM structure of an E. coli rotated ribosome complex bound with RF3-ppGpp and p/E-tRNAPhe (Composite state I-C)
Descriptor: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Rybak, M.Y, Li, L, Lin, J, Gagnon, M.G.
Deposit date:2023-01-28
Release date:2024-06-26
Last modified:2024-08-07
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:The ribosome termination complex remodels release factor RF3 and ejects GDP.
Nat.Struct.Mol.Biol., 2024
8G38
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BU of 8g38 by Molmil
Time-resolved cryo-EM study of the 70S recycling by the HflX:3rd Intermediate
Descriptor: 16S, 23S, 30S ribosomal protein S10, ...
Authors:Bhattacharjee, S, Brown, P.Z, Frank, J.
Deposit date:2023-02-07
Release date:2023-12-06
Last modified:2024-02-14
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Time resolution in cryo-EM using a PDMS-based microfluidic chip assembly and its application to the study of HflX-mediated ribosome recycling.
Cell, 187, 2024
8T5H
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BU of 8t5h by Molmil
Cryo-EM studies of the interplay between uS2 ribosomal protein and leaderless mRNA during bacterial translation initiation
Descriptor: 16S, 23S, 30S ribosomal protein S10, ...
Authors:Bhattacharjee, S, Gottesman, M.E, Frank, J.
Deposit date:2023-06-13
Release date:2024-08-28
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:How Dedicated Ribosomes Translate a Leaderless mRNA.
J.Mol.Biol., 436, 2024

 

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