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PDB: 11 results
4U89
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BU of 4u89 by Molmil
4'-phosphopantetheinyl transferase PptT from Mycobacterium tuberculosis
Descriptor: COENZYME A, IMIDAZOLE, PHOSPHATE ION, ...
Authors:Faille, A, Mourey, L, Pedelacq, J.D.
Deposit date:2014-08-01
Release date:2015-08-26
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:X-ray structure of the 4'-phosphopantetheinyl transferase PptT from Mycobacterium tuberculosis
to be published
7N8M
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BU of 7n8m by Molmil
PptT PAP(CoA) 8978B complex
Descriptor: 4'-phosphopantetheinyl transferase PptT, COENZYME A, DIMETHYL SULFOXIDE, ...
Authors:Mosior, J.W, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC)
Deposit date:2021-06-15
Release date:2022-02-02
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.57 Å)
Cite:In Vitro and In Vivo Inhibition of the Mycobacterium tuberculosis Phosphopantetheinyl Transferase PptT by Amidinoureas.
J.Med.Chem., 65, 2022
4QJK
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Crystal structure of M. tuberculosis phosphopantetheinyl transferase PptT
Descriptor: COENZYME A, Phosphopantetheinyl transferase PptT, SULFATE ION
Authors:Noel, J.P, Burkart, M.D, Vickery, C.R.
Deposit date:2014-06-04
Release date:2014-07-16
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.59 Å)
Cite:Structure, biochemistry, and inhibition of essential 4'-phosphopantetheinyl transferases from two species of mycobacteria.
Acs Chem.Biol., 9, 2014
7ED0
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BU of 7ed0 by Molmil
Transferase from Mycobacterium tuberculosis
Descriptor: 4'-phosphopantetheinyl transferase superfamily protein, COENZYME A, SULFATE ION
Authors:Kim, D.-G, Lee, B.-J, Lee, S.J.
Deposit date:2021-03-15
Release date:2022-03-16
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Transferase from Mycobacterium tuberculosis
To Be Published
8QZH
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BU of 8qzh by Molmil
Crystal structure of apo-PptT from Mycobacterium tuberculosis
Descriptor: 4'-phosphopantetheinyl transferase PptT, ACETATE ION, MAGNESIUM ION
Authors:Gavalda, S, Carivenc, C, Mourey, L, Pedelacq, J.D.
Deposit date:2023-10-27
Release date:2024-06-19
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Catalytic Cycle of Type II 4'-Phosphopantetheinyl Transferases
Acs Catalysis, 14, 2024
7N8E
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BU of 7n8e by Molmil
PptT PAP(CoA) 9056 complex
Descriptor: 4'-phosphopantetheinyl transferase PptT, COENZYME A, DIMETHYL SULFOXIDE, ...
Authors:Mosior, J.W, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC)
Deposit date:2021-06-14
Release date:2022-02-02
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:In Vitro and In Vivo Inhibition of the Mycobacterium tuberculosis Phosphopantetheinyl Transferase PptT by Amidinoureas.
J.Med.Chem., 65, 2022
4QVH
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BU of 4qvh by Molmil
Crystal structure of the essential Mycobacterium tuberculosis phosphopantetheinyl transferase PptT, solved as a fusion protein with maltose binding protein
Descriptor: CITRATE ANION, COENZYME A, GLYCEROL, ...
Authors:Jung, J, Bashiri, G, Johnston, J.M, Baker, E.N.
Deposit date:2014-07-15
Release date:2014-12-17
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Crystal structure of the essential Mycobacterium tuberculosis phosphopantetheinyl transferase PptT, solved as a fusion protein with maltose binding protein.
J.Struct.Biol., 188, 2014
8QZJ
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BU of 8qzj by Molmil
Crystal structure of PptT-ADP from Mycobacterium tuberculosis
Descriptor: 4'-phosphopantetheinyl transferase PptT, ADENOSINE-3'-5'-DIPHOSPHATE, MANGANESE (II) ION
Authors:Gavalda, S, Mourey, L, Pedelacq, J.D.
Deposit date:2023-10-27
Release date:2024-06-19
Method:X-RAY DIFFRACTION (2 Å)
Cite:Catalytic Cycle of Type II 4'-Phosphopantetheinyl Transferases
Acs Catalysis, 14, 2024
7N8L
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BU of 7n8l by Molmil
PptT PAP(CoA) 9016 complex
Descriptor: 4'-phosphopantetheinyl transferase PptT, COENZYME A, DIMETHYL SULFOXIDE, ...
Authors:Mosior, J.W, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC)
Deposit date:2021-06-15
Release date:2022-02-02
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:In Vitro and In Vivo Inhibition of the Mycobacterium tuberculosis Phosphopantetheinyl Transferase PptT by Amidinoureas.
J.Med.Chem., 65, 2022
8GKF
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BU of 8gkf by Molmil
Phosphopantetheinyl transferase PptT from Mycobacterium tuberculosis in complex with Raltitrexed.
Descriptor: 4'-phosphopantetheinyl transferase PptT, TOMUDEX
Authors:Krieger, I.V, Singh, A, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC)
Deposit date:2023-03-18
Release date:2024-03-20
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Redirecting raltitrexed from cancer cell thymidylate synthase to Mycobacterium tuberculosis phosphopantetheinyl transferase.
Sci Adv, 10, 2024
8QZI
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BU of 8qzi by Molmil
Crystal structure of PptT-ACP from Mycobacterium tuberculosis
Descriptor: 4'-phosphopantetheinyl transferase PptT, COENZYME A, ISOPROPYL ALCOHOL, ...
Authors:Gavalda, S, Mourey, L, Pedelacq, J.D.
Deposit date:2023-10-27
Release date:2024-06-19
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Catalytic Cycle of Type II 4'-Phosphopantetheinyl Transferases
Acs Catalysis, 14, 2024

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