8JCC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8jcc by Molmil](/molmil-images/mine/8jcc) | |
7Y7I
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7y7i by Molmil](/molmil-images/mine/7y7i) | chicken KNL2 in complex with the CENP-A nucleosome | Descriptor: | Chains: I, Chains: J, Histone H2A type 1-B/E, ... | Authors: | Ariyoshi, M, Jiang, H, Makino, F, Fukagawa, T. | Deposit date: | 2022-06-22 | Release date: | 2022-07-13 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (3.42 Å) | Cite: | The cryo-EM structure of the CENP-A nucleosome in complex with ggKNL2. Biorxiv, 2022
|
|
3W98
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3w98 by Molmil](/molmil-images/mine/3w98) | Crystal Structure of Human Nucleosome Core Particle lacking H3.1 N-terminal region | Descriptor: | 146-mer DNA, Histone H2A type 1-B/E, Histone H2B type 1-J, ... | Authors: | Iwasaki, W, Miya, Y, Horikoshi, N, Osakabe, A, Tachiwana, H, Shibata, T, Kagawa, W, Kurumizaka, H. | Deposit date: | 2013-04-01 | Release date: | 2013-08-28 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (3.42 Å) | Cite: | Contribution of histone N-terminal tails to the structure and stability of nucleosomes FEBS Open Bio, 3, 2013
|
|
8JLA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8jla by Molmil](/molmil-images/mine/8jla) | Cryo-EM structure of the human nucleosome lacking N-terminal region of H2A, H2B, H3, and H4 | Descriptor: | DNA (193-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ... | Authors: | Oishi, T, Hatazawa, S, Kujirai, T, Kato, J, Kobayashi, Y, Ogasawara, M, Akatsu, M, Takizawa, Y, Kurumizaka, H. | Deposit date: | 2023-06-02 | Release date: | 2023-10-04 | Last modified: | 2023-11-08 | Method: | ELECTRON MICROSCOPY (3.44 Å) | Cite: | Contributions of histone tail clipping and acetylation in nucleosome transcription by RNA polymerase II. Nucleic Acids Res., 51, 2023
|
|
8IEG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8ieg by Molmil](/molmil-images/mine/8ieg) | Bre1(mRBD-RING)/Rad6-Ub/nucleosome complex | Descriptor: | DNA (147-MER), E3 ubiquitin-protein ligase BRE1, Histone H2A type 1-B/E, ... | Authors: | Ai, H, Deng, Z, Pan, M, Liu, L. | Deposit date: | 2023-02-15 | Release date: | 2023-09-06 | Last modified: | 2023-09-20 | Method: | ELECTRON MICROSCOPY (3.44 Å) | Cite: | Mechanistic insights into nucleosomal H2B monoubiquitylation mediated by yeast Bre1-Rad6 and its human homolog RNF20/RNF40-hRAD6A. Mol.Cell, 83, 2023
|
|
8ATF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8atf by Molmil](/molmil-images/mine/8atf) | Nucleosome-bound Ino80 ATPase | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, DNA (226-MER), DNA (227-MER), ... | Authors: | Kunert, F, Metzner, F.J, Eustermann, S, Jung, J, Woike, S, Schall, K, Kostrewa, D, Hopfner, K.P. | Deposit date: | 2022-08-23 | Release date: | 2022-12-14 | Last modified: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (3.45 Å) | Cite: | Structural mechanism of extranucleosomal DNA readout by the INO80 complex. Sci Adv, 8, 2022
|
|
7XD0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7xd0 by Molmil](/molmil-images/mine/7xd0) | cryo-EM structure of H2BK34ub nucleosome | Descriptor: | DNA (146-MER), Histone H2A, Histone H2B type 1-K, ... | Authors: | Ai, H.S, Liu, A.J, Lou, Z.Y, Liu, L. | Deposit date: | 2022-03-26 | Release date: | 2022-04-20 | Last modified: | 2024-06-26 | Method: | ELECTRON MICROSCOPY (3.48 Å) | Cite: | H2B Lys34 Ubiquitination Induces Nucleosome Distortion to Stimulate Dot1L Activity. Nat.Chem.Biol., 18, 2022
|
|
3AZH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3azh by Molmil](/molmil-images/mine/3azh) | Crystal Structure of Human Nucleosome Core Particle Containing H3K122Q mutation | Descriptor: | 146-MER DNA, CHLORIDE ION, Histone H2A type 1-B/E, ... | Authors: | Iwasaki, W, Tachiwana, H, Kawaguchi, K, Shibata, T, Kagawa, W, Kurumizaka, H. | Deposit date: | 2011-05-25 | Release date: | 2011-09-21 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (3.49 Å) | Cite: | Comprehensive Structural Analysis of Mutant Nucleosomes Containing Lysine to Glutamine (KQ) Substitutions in the H3 and H4 Histone-Fold Domains Biochemistry, 50, 2011
|
|
6T93
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6t93 by Molmil](/molmil-images/mine/6t93) | Nucleosome with OCT4-SOX2 motif at SHL-6 | Descriptor: | DNA (153-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ... | Authors: | Michael, A.K, Kempf, G, Cavadini, S, Bunker, R.D, Thoma, N.H. | Deposit date: | 2019-10-25 | Release date: | 2020-05-06 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (3.49 Å) | Cite: | Mechanisms of OCT4-SOX2 motif readout on nucleosomes. Science, 368, 2020
|
|
7Y5W
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7y5w by Molmil](/molmil-images/mine/7y5w) | Cryo-EM structure of the left-handed Di-tetrasome | Descriptor: | Histone H3.1, Histone H4, Widom 601 DNA (147-MER) | Authors: | Liu, C.P, Yu, Z.Y, Yu, C, Xu, R.M. | Deposit date: | 2022-06-17 | Release date: | 2023-08-16 | Last modified: | 2023-09-06 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structural insights into histone binding and nucleosome assembly by chromatin assembly factor-1. Science, 381, 2023
|
|
7SCZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7scz by Molmil](/molmil-images/mine/7scz) | Nuc147 bound to multiple BRCTs | Descriptor: | DNA (147-MER), Histone H2A, Histone H2B type 1-J, ... | Authors: | Muthurajan, U.M, Rudolph, J. | Deposit date: | 2021-09-29 | Release date: | 2022-01-19 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | The BRCT domain of PARP1 binds intact DNA and mediates intrastrand transfer. Mol.Cell, 81, 2021
|
|
8OL1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8ol1 by Molmil](/molmil-images/mine/8ol1) | |
7NL0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7nl0 by Molmil](/molmil-images/mine/7nl0) | Cryo-EM structure of the Lin28B nucleosome core particle | Descriptor: | DNA (131-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ... | Authors: | Roberts, G.A, Ozkan, B, Gachulincova, I, O Dwyer, M.R, Hall-Ponsele, E, Saxena, M, Robinson, P.J, Soufi, A. | Deposit date: | 2021-02-19 | Release date: | 2021-08-11 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Dissecting OCT4 defines the role of nucleosome binding in pluripotency. Nat.Cell Biol., 23, 2021
|
|
5C3I
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5c3i by Molmil](/molmil-images/mine/5c3i) | Crystal structure of the quaternary complex of histone H3-H4 heterodimer with chaperone ASF1 and the replicative helicase subunit MCM2 | Descriptor: | DNA replication licensing factor MCM2,MCM2, Histone H3.1, Histone H4, ... | Authors: | Wang, H, Wang, M, Yang, N, Xu, R.M. | Deposit date: | 2015-06-17 | Release date: | 2015-07-29 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Structure of the quaternary complex of histone H3-H4 heterodimer with chaperone ASF1 and the replicative helicase subunit MCM2 Protein Cell, 6, 2015
|
|
6SE6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6se6 by Molmil](/molmil-images/mine/6se6) | Class2 : CENP-A nucleosome in complex with CENP-C central region | Descriptor: | Centromere protein C, DNA (145-MER), Histone H2A type 2-A, ... | Authors: | Ali-Ahmad, A, Bilokapic, S, Schafer, I.B, Halic, M, Sekulic, N. | Deposit date: | 2019-07-29 | Release date: | 2019-08-14 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | CENP-C unwraps the human CENP-A nucleosome through the H2A C-terminal tail. Embo Rep., 20, 2019
|
|
6R94
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6r94 by Molmil](/molmil-images/mine/6r94) | Cryo-EM structure of NCP_THF2(-3) | Descriptor: | Histone H2A type 1-B/E, Histone H2B type 1-J, Histone H3.1, ... | Authors: | Matsumoto, S, Cavadini, S, Bunker, R.D, Thoma, N.H. | Deposit date: | 2019-04-02 | Release date: | 2019-06-12 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | DNA damage detection in nucleosomes involves DNA register shifting. Nature, 571, 2019
|
|
8IQG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8iqg by Molmil](/molmil-images/mine/8iqg) | Cryo-EM structure of the monomeric human CAF1-H3-H4 complex | Descriptor: | Chromatin assembly factor 1 subunit A, Chromatin assembly factor 1 subunit B, Histone H3.1, ... | Authors: | Liu, C.P, Yu, Z.Y, Xu, R.M. | Deposit date: | 2023-03-16 | Release date: | 2023-08-16 | Last modified: | 2023-09-06 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structural insights into histone binding and nucleosome assembly by chromatin assembly factor-1. Science, 381, 2023
|
|
5KDM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5kdm by Molmil](/molmil-images/mine/5kdm) | |
7V90
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7v90 by Molmil](/molmil-images/mine/7v90) | Telomeric mononucleosome | Descriptor: | DNA (145-mer), Histone H2A type 1-B/E, Histone H2B type 1-K, ... | Authors: | Soman, A. | Deposit date: | 2021-08-24 | Release date: | 2022-07-27 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Columnar structure of human telomeric chromatin. Nature, 609, 2022
|
|
6MUP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6mup by Molmil](/molmil-images/mine/6mup) | |
7XVL
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7xvl by Molmil](/molmil-images/mine/7xvl) | Crystal Structure of Nucleosome-H1.0 Linker Histone Assembly (sticky-169an DNA fragment) | Descriptor: | DNA (169-MER), Histone H1.0, Histone H2A type 1-B/E, ... | Authors: | Adhireksan, Z, Qiuye, B, Lee, P.L, Sharma, D, Padavattan, S, Davey, C.A. | Deposit date: | 2022-05-24 | Release date: | 2023-05-24 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (3.506 Å) | Cite: | Crystal Structure of Nucleosome-H1.0 Linker Histone Assembly (sticky-169an DNA fragment) To Be Published
|
|
4YM6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4ym6 by Molmil](/molmil-images/mine/4ym6) | Crystal structure of the human nucleosome containing 6-4PP (outside) | Descriptor: | 145-MER DNA, Histone H2A type 1-B/E, Histone H2B type 1-J, ... | Authors: | Osakabe, A, Tachiwana, H, Kagawa, W, Horikoshi, N, Matsumoto, S, Hasegawa, M, Matsumoto, N, Toga, T, Yamamoto, J, Hanaoka, F, Thoma, N.H, Sugasawa, K, Iwai, S, Kurumizaka, H. | Deposit date: | 2015-03-06 | Release date: | 2015-12-02 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (3.514 Å) | Cite: | Structural basis of pyrimidine-pyrimidone (6-4) photoproduct recognition by UV-DDB in the nucleosome Sci Rep, 5, 2015
|
|
8JHG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8jhg by Molmil](/molmil-images/mine/8jhg) | Native SUV420H1 bound to 167-bp nucleosome | Descriptor: | DNA (160-MER), Histone H2A type 1-B/E, Histone H2B type 1-K, ... | Authors: | Lin, F, Li, W. | Deposit date: | 2023-05-23 | Release date: | 2023-11-22 | Last modified: | 2023-12-20 | Method: | ELECTRON MICROSCOPY (3.58 Å) | Cite: | Structural basis of nucleosomal H4K20 recognition and methylation by SUV420H1 methyltransferase. Cell Discov, 9, 2023
|
|
8SN2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8sn2 by Molmil](/molmil-images/mine/8sn2) | Cryo-EM structure of the human nucleosome core particle in complex with RNF168 and UbcH5c (UbcH5c chemically conjugated to histone H2A) | Descriptor: | DNA (147-MER), E3 ubiquitin-protein ligase RNF168, Histone H2A type 1-B/E, ... | Authors: | Hu, Q, Botuyan, M.V, Zhao, D, Cui, G, Mer, G. | Deposit date: | 2023-04-26 | Release date: | 2024-01-17 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Mechanisms of RNF168 nucleosome recognition and ubiquitylation. Mol.Cell, 84, 2024
|
|
8TXW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8txw by Molmil](/molmil-images/mine/8txw) | Cryo-EM structure of the human nucleosome core particle ubiquitylated at histone H2A K15 in complex with RNF168 (Class 2) | Descriptor: | DNA (147-MER), E3 ubiquitin-protein ligase RNF168, Histone H2A type 1-B/E, ... | Authors: | Hu, Q, Botuyan, M.V, Zhao, D, Cui, G, Mer, G. | Deposit date: | 2023-08-24 | Release date: | 2024-01-17 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Mechanisms of RNF168 nucleosome recognition and ubiquitylation. Mol.Cell, 84, 2024
|
|