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PDB: 7 results

6QB6
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BU of 6qb6 by Molmil
Mcl1 in complex with a Fab
Descriptor: Fab Heavy Chain, Fab Light Chain, Induced myeloid leukemia cell differentiation protein Mcl-1
Authors:Hargreaves, D.
Deposit date:2018-12-20
Release date:2019-11-06
Last modified:2019-11-13
Method:X-RAY DIFFRACTION (2.24 Å)
Cite:Antibody fragments structurally enable a drug-discovery campaign on the cancer target Mcl-1.
Acta Crystallogr D Struct Biol, 75, 2019
6QB3
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BU of 6qb3 by Molmil
Apo Mcl1 in a complex with a scFv
Descriptor: Induced myeloid leukemia cell differentiation protein Mcl-1, scFv55
Authors:Kazmirski, S, Hargreaves, D.
Deposit date:2018-12-20
Release date:2019-11-06
Last modified:2019-11-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Antibody fragments structurally enable a drug-discovery campaign on the cancer target Mcl-1.
Acta Crystallogr D Struct Biol, 75, 2019
6QB4
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BU of 6qb4 by Molmil
Mcl1-scFv complex with an indole acid inhibitor
Descriptor: 3-[3-[[(1~{R})-1,2,3,4-tetrahydronaphthalen-1-yl]oxy]propyl]-7-(1,3,5-trimethylpyrazol-4-yl)-1~{H}-indole-2-carboxylic acid, Induced myeloid leukemia cell differentiation protein Mcl-1, scFv55
Authors:Hargreaves, D.
Deposit date:2018-12-20
Release date:2019-11-06
Last modified:2019-11-13
Method:X-RAY DIFFRACTION (2.38 Å)
Cite:Antibody fragments structurally enable a drug-discovery campaign on the cancer target Mcl-1.
Acta Crystallogr D Struct Biol, 75, 2019
6QB9
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BU of 6qb9 by Molmil
Structure of an anti-Mcl1 scFv
Descriptor: L(+)-TARTARIC ACID, scFv55
Authors:Hargreaves, D.
Deposit date:2018-12-20
Release date:2019-11-06
Last modified:2019-11-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Antibody fragments structurally enable a drug-discovery campaign on the cancer target Mcl-1.
Acta Crystallogr D Struct Biol, 75, 2019
6QF9
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BU of 6qf9 by Molmil
Structure of an anti-Mcl1 scFv
Descriptor: scFv
Authors:Luptak, J.
Deposit date:2019-01-09
Release date:2019-11-06
Last modified:2019-11-13
Method:X-RAY DIFFRACTION (1.43 Å)
Cite:Antibody fragments structurally enable a drug-discovery campaign on the cancer target Mcl-1.
Acta Crystallogr D Struct Biol, 75, 2019
6QFC
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BU of 6qfc by Molmil
Structure of an anti-Mcl1 scFv
Descriptor: DIMETHYL SULFOXIDE, Induced myeloid leukemia cell differentiation protein Mcl-1, scFv55
Authors:Luptak, J.
Deposit date:2019-01-09
Release date:2019-11-06
Last modified:2019-11-13
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:Antibody fragments structurally enable a drug-discovery campaign on the cancer target Mcl-1.
Acta Crystallogr D Struct Biol, 75, 2019
6QBC
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BU of 6qbc by Molmil
structure of anti-Mcl1 Fab
Descriptor: Anti-Mcl1 Fab Heavy Chain, Anti-Mcl1 Fab Light Chain
Authors:Luptak, J.
Deposit date:2018-12-20
Release date:2019-11-06
Last modified:2019-11-13
Method:X-RAY DIFFRACTION (1.56 Å)
Cite:Antibody fragments structurally enable a drug-discovery campaign on the cancer target Mcl-1.
Acta Crystallogr D Struct Biol, 75, 2019

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