6QBC
structure of anti-Mcl1 Fab
Summary for 6QBC
Entry DOI | 10.2210/pdb6qbc/pdb |
Related | 6FS0 |
Descriptor | Anti-Mcl1 Fab Heavy Chain, Anti-Mcl1 Fab Light Chain (3 entities in total) |
Functional Keywords | mcl1, fab, azd5991, apoptosis |
Biological source | Homo sapiens More |
Total number of polymer chains | 2 |
Total formula weight | 47983.18 |
Authors | Luptak, J. (deposition date: 2018-12-20, release date: 2019-11-06, Last modification date: 2019-11-13) |
Primary citation | Luptak, J.,Bista, M.,Fisher, D.,Flavell, L.,Gao, N.,Wickson, K.,Kazmirski, S.L.,Howard, T.,Rawlins, P.B.,Hargreaves, D. Antibody fragments structurally enable a drug-discovery campaign on the cancer target Mcl-1. Acta Crystallogr D Struct Biol, 75:1003-1014, 2019 Cited by PubMed: 31692474DOI: 10.1107/S2059798319014116 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.56 Å) |
Structure validation
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