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7MFB
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Crystal structure of antibody 10E8v4 Fab - light chain H31F variant
Descriptor: Antibody 10E8v4 Fab heavy chain, Antibody 10E8v4 Fab light chain
Authors:Kwon, Y.D, Kwong, P.D.
Deposit date:2021-04-08
Release date:2021-07-14
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:Structures of HIV-1 Neutralizing Antibody 10E8 Delineate the Mechanistic Basis of Its Multi-Peak Behavior on Size-Exclusion Chromatography.
Antibodies, 10, 2021
7MFA
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BU of 7mfa by Molmil
Crystal structure of antibody 10E8v4-P100fA+P100gA Fab
Descriptor: Antibody 10E8v4 Fab heavy chain, Antibody 10E8v4 Fab light chain
Authors:Kwon, Y.D, Kwong, P.D.
Deposit date:2021-04-08
Release date:2021-07-14
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structures of HIV-1 Neutralizing Antibody 10E8 Delineate the Mechanistic Basis of Its Multi-Peak Behavior on Size-Exclusion Chromatography.
Antibodies, 10, 2021
7MF7
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BU of 7mf7 by Molmil
Crystal structure of antibody 10E8v4-P100gA Fab
Descriptor: Antibody 10E8v4 Fab heavy chain, Antibody 10E8v4 Fab light chain
Authors:Kwon, Y.D, Kwong, P.D.
Deposit date:2021-04-08
Release date:2021-07-14
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structures of HIV-1 Neutralizing Antibody 10E8 Delineate the Mechanistic Basis of Its Multi-Peak Behavior on Size-Exclusion Chromatography.
Antibodies, 10, 2021
7MF8
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BU of 7mf8 by Molmil
Crystal structure of antibody 10E8v4-P100fA Fab in space group P6422
Descriptor: Antibody 10E8v4 Fab heavy chain, Antibody 10E8v4 Fab light chain
Authors:Kwon, Y.D, Kwong, P.D.
Deposit date:2021-04-08
Release date:2021-07-14
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structures of HIV-1 Neutralizing Antibody 10E8 Delineate the Mechanistic Basis of Its Multi-Peak Behavior on Size-Exclusion Chromatography.
Antibodies, 10, 2021
7MF9
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BU of 7mf9 by Molmil
Crystal structure of antibody 10E8v4-P100fA Fab in space group C2
Descriptor: Antibody 10E8v4 Fab heavy chain, Antibody 10E8v4 Fab light chain
Authors:Kwon, Y.D, Kwong, P.D.
Deposit date:2021-04-08
Release date:2021-07-14
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.7 Å)
Cite:Structures of HIV-1 Neutralizing Antibody 10E8 Delineate the Mechanistic Basis of Its Multi-Peak Behavior on Size-Exclusion Chromatography.
Antibodies, 10, 2021
7KQY
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BU of 7kqy by Molmil
Crystal Structure and Characterization of Human Heavy-Chain only Antibodies reveals a novel, stable dimeric structure similar to Monoclonal Antibodies
Descriptor: Heavy-Chain only Human Antibodies
Authors:Bahmanjah, S, Mieczkowski, C, Yu, Y, Baker, J, Raghunathan, G, Tomazela, D, Hsieh, M, Mccoy, M, Strickland, C, Fayadat-Dilman, L.
Deposit date:2020-11-18
Release date:2020-12-16
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.913 Å)
Cite:Crystal Structure and Characterization of Human Heavy-Chain Only Antibodies Reveals a Novel, Stable Dimeric Structure Similar to Monoclonal Antibodies.
Antibodies, 9, 2020
6VRT
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BU of 6vrt by Molmil
LT1009 humanized antibody Fab fragment in complex with calcium
Descriptor: CALCIUM ION, SULFATE ION, Sonepcizumab antibody Fab fragment, ...
Authors:Fleming, J.K, Huxford, T.
Deposit date:2020-02-09
Release date:2020-04-29
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.555 Å)
Cite:Ion binding properties of a naturally occurring metalloantibody
Antibodies, 9, 2020
5WKO
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BU of 5wko by Molmil
Crystal structure of antibody 27F3 recognizing the HA from A/California/04/2009 (H1N1) influenza virus
Descriptor: Antibody 27F3 heavy chain, Antibody 27F3 light chain, Hemagglutinin
Authors:Wilson, I.A, Lang, S, Zhu, X.
Deposit date:2017-07-25
Release date:2017-10-25
Last modified:2024-05-15
Method:X-RAY DIFFRACTION (3.492 Å)
Cite:Antibody 27F3 Broadly Targets Influenza A Group 1 and 2 Hemagglutinins through a Further Variation in VH1-69 Antibody Orientation on the HA Stem.
Cell Rep, 20, 2017
8Q6K
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BU of 8q6k by Molmil
Human IgD Fab in complex with an orthosteric inhibitor of Phl p 7
Descriptor: 1,2-ETHANEDIOL, ACETATE ION, Human IgD Fab heavy chain, ...
Authors:Davies, A.M, Vester, S.K, McDonnell, J.M.
Deposit date:2023-08-11
Release date:2023-12-06
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Expanding the Anti-Phl p 7 Antibody Toolkit: An Anti-Idiotype Nanobody Inhibitor.
Antibodies, 12, 2023
7KFG
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BU of 7kfg by Molmil
Antibody Fab BDBV-289
Descriptor: Antibody Fab BDBV-289 heavy chain, Antibody Fab BDBV-289 light chain, DI(HYDROXYETHYL)ETHER
Authors:Murin, C.D, Bruhn, J.F, Ward, A.B.
Deposit date:2020-10-13
Release date:2021-04-28
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (3.002 Å)
Cite:Convergence of a common solution for broad ebolavirus neutralization by glycan cap-directed human antibodies.
Cell Rep, 35, 2021
5LDN
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BU of 5ldn by Molmil
A viral capsid:antibody complex
Descriptor: Hexon protein,hexon capsid, antibody
Authors:James, L.
Deposit date:2016-06-27
Release date:2017-07-12
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Antibody-antigen kinetics constrain intracellular humoral immunity.
Sci Rep, 6, 2016
5E94
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BU of 5e94 by Molmil
Antibody-bound Glucagon-like Peptide-1 receptor extracellular domain
Descriptor: Antibody Fab fragment heavy chain, Antibody Fab fragment light chain, Glucagon-like peptide 1 receptor
Authors:Soroka, V, Schluckebier, G, Reedtz-Runge, S.
Deposit date:2015-10-14
Release date:2016-08-24
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural insight into antibody-mediated antagonism of the Glucagon-like peptide-1 Receptor.
Sci Rep, 6, 2016
6OSV
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BU of 6osv by Molmil
Potent and Selective Antitumor Antibody Targeting a Membrane-Proximal Epitope of ROR2
Descriptor: Antibody heavy chain variable region, Antibody light chain variable region, Tyrosine-protein kinase transmembrane receptor ROR2
Authors:Park, H, Rader, C.
Deposit date:2019-05-02
Release date:2020-04-01
Last modified:2020-05-13
Method:X-RAY DIFFRACTION (1.34 Å)
Cite:Affinity maturation, humanization, and co-crystallization of a rabbit anti-human ROR2 monoclonal antibody for therapeutic applications.
J.Biol.Chem., 295, 2020
6OSH
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BU of 6osh by Molmil
Potent and Selective Antitumor Antibody Targeting a Membrane-Proximal Epitope of ROR2
Descriptor: Antibody Light chain variable region, Antibody heavy chain variable region, Tyrosine-protein kinase transmembrane receptor ROR2
Authors:Park, H, Rader, C.
Deposit date:2019-05-01
Release date:2020-04-01
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.117 Å)
Cite:Affinity maturation, humanization, and co-crystallization of a rabbit anti-human ROR2 monoclonal antibody for therapeutic applications.
J.Biol.Chem., 295, 2020
2AK1
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BU of 2ak1 by Molmil
Crystal Structure of Cocaine catalytic Antibody 7A1 Fab' in Complex with benzoic acid
Descriptor: Antibody 7A1 Fab', BENZOIC ACID, ZINC ION
Authors:Zhu, X, Wilson, I.A.
Deposit date:2005-08-02
Release date:2006-02-14
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Complete reaction cycle of a cocaine catalytic antibody at atomic resolution.
Structure, 14, 2006
2AJU
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BU of 2aju by Molmil
Cyrstal structure of cocaine catalytic antibody 7A1 Fab'
Descriptor: ANTIBODY 7A1 FAB'
Authors:Zhu, X, Wilson, I.A.
Deposit date:2005-08-02
Release date:2006-02-14
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Complete reaction cycle of a cocaine catalytic antibody at atomic resolution.
Structure, 14, 2006
2AJV
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BU of 2ajv by Molmil
Crystal Structure of Cocaine catalytic Antibody 7A1 Fab' in Complex with Cocaine
Descriptor: Antibody 7A1 Fab', COCAINE
Authors:Zhu, X, Wilson, I.A.
Deposit date:2005-08-02
Release date:2006-02-14
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Complete reaction cycle of a cocaine catalytic antibody at atomic resolution.
Structure, 14, 2006
5CCK
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BU of 5cck by Molmil
Crystal structure of Human anti-HIV-1 broadly neutralizing antibody 3BC315 Fab
Descriptor: 3-CYCLOHEXYL-1-PROPYLSULFONIC ACID, Antibody 3BC315 Fab heavy chain, Antibody 3BC315 Fab light chain
Authors:Lee, J.H, Ward, A.B, Wilson, I.A.
Deposit date:2015-07-02
Release date:2015-10-07
Last modified:2019-12-11
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Antibodies to a conformational epitope on gp41 neutralize HIV-1 by destabilizing the Env spike.
Nat Commun, 6, 2015
3I75
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BU of 3i75 by Molmil
Antibody Structure
Descriptor: Antibody heavy chain, Antibody light chain, CHLORIDE ION, ...
Authors:Isaacs, N.W, Riboldi-Tunnicliffe, A.
Deposit date:2009-07-08
Release date:2010-07-21
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Antibody Structure
To be Published
6N16
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BU of 6n16 by Molmil
Vaccine-elicited NHP FP-targeting neutralizing antibody 0PV-b.01 in complex with HIV fusion peptide (residue 512-519)
Descriptor: HIV fusion peptide (512-519), antibody 0PV-b.01 Fab heavy chain, antibody 0PV-b.01 Fab light chain
Authors:Xu, K, Wang, Y, Kwong, P.D.
Deposit date:2018-11-08
Release date:2019-07-31
Last modified:2019-11-13
Method:X-RAY DIFFRACTION (2.302 Å)
Cite:Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization.
Cell, 178, 2019
1CFV
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BU of 1cfv by Molmil
MONOCLONAL ANTIBODY FRAGMENT FV4155 FROM E. COLI
Descriptor: ESTRONE BETA-D-GLUCURONIDE, MONOCLONAL ANTIBODY FV4155, ZINC ION
Authors:Trinh, C.H, Phillips, S.E.V.
Deposit date:1997-04-11
Release date:1997-10-15
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Antibody fragment Fv4155 bound to two closely related steroid hormones: the structural basis of fine specificity.
Structure, 5, 1997
6MQC
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BU of 6mqc by Molmil
Vaccine-elicited NHP FP-targeting neutralizing antibody 0PV-c.01 in complex with FP (residue 512-519)
Descriptor: 0PV-C.01 antibody Fab heavy chain, 0PV-C.01 antibody Fab light chain, HIV fusion peptide residue 512-519
Authors:Xu, K, Wang, Y, Kwong, P.D.
Deposit date:2018-10-09
Release date:2019-07-31
Last modified:2019-11-13
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization.
Cell, 178, 2019
4QF1
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BU of 4qf1 by Molmil
Crystal structure of unliganded CH59UA, the inferred unmutated ancestor of the RV144 anti-HIV antibody lineage producing CH59
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CH59UA Fab fragment of heavy chain, CHLORIDE ION, ...
Authors:Wiehe, K, Easterhoff, D, Luo, K, Nicely, N.I, Bradley, T, Jaeger, F.H, Dennison, S.M, Zhang, R, Lloyd, K.E, Stolarchuk, C, Parks, R, Sutherland, L.L, Scearce, R.M, Morris, L, Kaewkungwal, J, Nitayaphan, S, Pitisuttithum, P, Rerks-Ngarm, S, Michael, N, Kim, J, Kelsoe, G, Montefiori, D.C, Tomaras, G, Bonsignori, M, Santra, S, Kepler, T.B, Alam, S.M, Moody, M.A, Liao, H.-X, Haynes, B.F.
Deposit date:2014-05-19
Release date:2015-02-18
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Antibody Light-Chain-Restricted Recognition of the Site of Immune Pressure in the RV144 HIV-1 Vaccine Trial Is Phylogenetically Conserved.
Immunity, 41, 2014
6MQM
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BU of 6mqm by Molmil
Vaccine-elicited NHP FP-targeting neutralizing antibody DF1W-a.01 in complex with HIV fusion peptide (residue 512-519)
Descriptor: HIV Env fusion peptide residue 512-519, antibody Fab heavy chain, antibody Fab light chain
Authors:Xu, K, Wang, Y, Kwong, P.D.
Deposit date:2018-10-10
Release date:2019-07-31
Last modified:2019-11-13
Method:X-RAY DIFFRACTION (3.484 Å)
Cite:Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization.
Cell, 178, 2019
6MQR
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BU of 6mqr by Molmil
Vaccine-elicited NHP FP-targeting neutralizing antibody 0PV-a.01 in complex with FP (residue 512-519)
Descriptor: CALCIUM ION, HIV fusion peptide residue 512-519, SULFATE ION, ...
Authors:Xu, K, Wang, Y, Kwong, P.D.
Deposit date:2018-10-10
Release date:2019-07-31
Last modified:2019-11-13
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization.
Cell, 178, 2019

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數據於2024-07-24公開中

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