7CKV
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![BU of 7ckv by Molmil](/molmil-images/mine/7ckv) | Crystal structure of Cyanobacteriochrome GAF domain in Pr state | Descriptor: | MAGNESIUM ION, PHYCOCYANOBILIN, RcaE | Authors: | Nagae, T, Koizumi, T, Hirose, Y, Mishima, M. | Deposit date: | 2020-07-19 | Release date: | 2021-05-05 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.63 Å) | Cite: | Structural basis of the protochromic green/red photocycle of the chromatic acclimation sensor RcaE. Proc.Natl.Acad.Sci.USA, 118, 2021
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1YKD
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![BU of 1ykd by Molmil](/molmil-images/mine/1ykd) | Crystal Structure of the Tandem GAF Domains from a Cyanobacterial Adenylyl Cyclase: Novel Modes of Ligand-Binding and Dimerization | Descriptor: | ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, adenylate cyclase | Authors: | Martinez, S.E, Bruder, S, Schultz, A, Zheng, N, Schultz, J.E, Beavo, J.A, Linder, J.U. | Deposit date: | 2005-01-17 | Release date: | 2005-02-22 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structure of the tandem GAF domains from a cyanobacterial adenylyl cyclase: Modes of ligand binding and dimerization Proc.Natl.Acad.Sci.USA, 102, 2005
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1F5M
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![BU of 1f5m by Molmil](/molmil-images/mine/1f5m) | STRUCTURE OF THE GAF DOMAIN | Descriptor: | BROMIDE ION, GAF | Authors: | Ho, Y.S, Burden, L.M, Hurley, J.H. | Deposit date: | 2000-06-15 | Release date: | 2000-11-10 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structure of the GAF domain, a ubiquitous signaling motif and a new class of cyclic GMP receptor. EMBO J., 19, 2000
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2KLI
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![BU of 2kli by Molmil](/molmil-images/mine/2kli) | Structural Basis for the Photoconversion of A Phytochrome to the Activated FAR-RED LIGHT-ABSORBING Form | Descriptor: | PHYCOCYANOBILIN, Sensor protein | Authors: | Cornilescu, C.C, Cornilescu, G, Ulijasz, A.T, Zhang, J, Rivera, M, Vierstra, R.D, Markley, J.L, Center for Eukaryotic Structural Genomics (CESG) | Deposit date: | 2009-07-03 | Release date: | 2009-11-03 | Last modified: | 2022-03-16 | Method: | SOLUTION NMR | Cite: | Structural basis for the photoconversion of a phytochrome to the activated Pfr form Nature, 463, 2010
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3CI6
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![BU of 3ci6 by Molmil](/molmil-images/mine/3ci6) | Crystal structure of the GAF domain from Acinetobacter phosphoenolpyruvate-protein phosphotransferase | Descriptor: | 1-ETHOXY-2-(2-ETHOXYETHOXY)ETHANE, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | Authors: | Cuff, M.E, Shackelford, G, Kim, Y, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2008-03-10 | Release date: | 2008-05-13 | Last modified: | 2017-10-25 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Crystal structure of the GAF domain from Acinetobacter phosphoenolpyruvate-protein phosphotransferase. TO BE PUBLISHED
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2KOI
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![BU of 2koi by Molmil](/molmil-images/mine/2koi) | Refined solution structure of a cyanobacterial phytochrome GAF domain in the red light-absorbing ground state | Descriptor: | PHYCOCYANOBILIN, Sensor protein | Authors: | Cornilescu, C.C, Cornilescu, G, Ulijasz, A.T, Vierstra, R.D, Markley, J.L, Center for Eukaryotic Structural Genomics (CESG) | Deposit date: | 2009-09-22 | Release date: | 2009-11-03 | Last modified: | 2011-07-13 | Method: | SOLUTION NMR | Cite: | Structural basis for the photoconversion of a phytochrome to the activated Pfr form Nature, 463, 2010
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3DBA
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![BU of 3dba by Molmil](/molmil-images/mine/3dba) | Crystal structure of the cGMP-bound GAF a domain from the photoreceptor phosphodiesterase 6C | Descriptor: | Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha', GLYCEROL, GUANOSINE-3',5'-MONOPHOSPHATE | Authors: | Martinez, S.E, Heikaus, C.C, Klevit, R.E, Beavo, J.A. | Deposit date: | 2008-05-30 | Release date: | 2008-07-01 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.57 Å) | Cite: | The Structure of the GAF A Domain from Phosphodiesterase 6C Reveals Determinants of cGMP Binding, a Conserved Binding Surface, and a Large cGMP-dependent Conformational Change. J.Biol.Chem., 283, 2008
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2K31
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![BU of 2k31 by Molmil](/molmil-images/mine/2k31) | Solution Structure of cGMP-binding GAF domain of Phosphodiesterase 5 | Descriptor: | GUANOSINE-3',5'-MONOPHOSPHATE, Phosphodiesterase 5A, cGMP-specific | Authors: | Heikaus, C.C, Stout, J.R, Sekharan, M.R, Eakin, C.M, Rajagopal, P, Brzovic, P.S, Beavo, J.A, Klevit, R.E. | Deposit date: | 2008-04-16 | Release date: | 2008-06-03 | Last modified: | 2024-05-08 | Method: | SOLUTION NMR | Cite: | Solution Structure of the cGMP Binding GAF Domain from Phosphodiesterase 5: Insights into Nucleotide Selectivity, Dimerization, and cGMP-Dependent Conformational Change. J.Biol.Chem., 283, 2008
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2K2N
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![BU of 2k2n by Molmil](/molmil-images/mine/2k2n) | Solution structure of a cyanobacterial phytochrome GAF domain in the red light-absorbing ground state | Descriptor: | PHYCOCYANOBILIN, Sensor protein | Authors: | Cornilescu, C.C, Cornilescu, G, Ulijasz, A.T, Vierstra, R.D, Markley, J.L. | Deposit date: | 2008-04-04 | Release date: | 2008-09-23 | Last modified: | 2022-03-16 | Method: | SOLUTION NMR | Cite: | Solution structure of a cyanobacterial phytochrome GAF domain in the red-light-absorbing ground state. J.Mol.Biol., 383, 2008
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6OZB
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![BU of 6ozb by Molmil](/molmil-images/mine/6ozb) | Crystal structure of the phycoerythrobilin-bound GAF domain from a cyanobacterial phytochrome | Descriptor: | PHYCOERYTHROBILIN, Two-component sensor histidine kinase | Authors: | Heewhan, S, Xiaoli, Z, Yafang, S, Zhong, R, Wolfgang, G, Kai, H.Z, Xiaojing, Y. | Deposit date: | 2019-05-15 | Release date: | 2020-05-20 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | The interplay between chromophore and protein determines the extended excited state dynamics in a single-domain phytochrome. Proc.Natl.Acad.Sci.USA, 117, 2020
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6P58
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![BU of 6p58 by Molmil](/molmil-images/mine/6p58) | Dark and Steady State-Illuminated Crystal Structure of Cyanobacteriochrome Receptor PixJ at 150K | Descriptor: | 1,2-ETHANEDIOL, MAGNESIUM ION, Methyl-accepting chemotaxis protein, ... | Authors: | Clinger, J.A, Miller, M.D, Buirgie, E.S, Vierstra, R.D, Phillips Jr, G.N. | Deposit date: | 2019-05-29 | Release date: | 2019-12-18 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.499 Å) | Cite: | Photoreversible interconversion of a phytochrome photosensory module in the crystalline state. Proc.Natl.Acad.Sci.USA, 117, 2020
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6OZA
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![BU of 6oza by Molmil](/molmil-images/mine/6oza) | Crystal structure of the phycocyanobilin-bound GAF domain from a cyanobacterial phytochrome | Descriptor: | PHYCOCYANOBILIN, Two-component sensor histidine kinase | Authors: | Heewhan, S, Xiaoli, Z, Yafang, S, Zhong, R, Wolfgang, G, Kai, H.Z, Xiaojing, Y. | Deposit date: | 2019-05-15 | Release date: | 2020-05-20 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (3.002 Å) | Cite: | The interplay between chromophore and protein determines the extended excited state dynamics in a single-domain phytochrome. Proc.Natl.Acad.Sci.USA, 117, 2020
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5W10
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![BU of 5w10 by Molmil](/molmil-images/mine/5w10) | Lcd1 GAF domain in complex with cAMP ligand | Descriptor: | ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, cGMP-specific phosphodiesterase | Authors: | Guzzo, C.R, Maciel, N.K, Barbosa, A.S, Farah, C.S. | Deposit date: | 2017-06-01 | Release date: | 2017-06-28 | Last modified: | 2020-01-01 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Structural and Enzymatic Characterization of a cAMP-Dependent Diguanylate Cyclase from Pathogenic Leptospira Species. J. Mol. Biol., 429, 2017
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5HL6
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![BU of 5hl6 by Molmil](/molmil-images/mine/5hl6) | |
5DFY
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![BU of 5dfy by Molmil](/molmil-images/mine/5dfy) | |
5DFX
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![BU of 5dfx by Molmil](/molmil-images/mine/5dfx) | |
4BWI
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![BU of 4bwi by Molmil](/molmil-images/mine/4bwi) | Structure of the phytochrome Cph2 from Synechocystis sp. PCC6803 | Descriptor: | FORMIC ACID, GLUTAMIC ACID, GLYCEROL, ... | Authors: | Anders, K, Angerer, V, Widany, G.D, Mroginski, M.A, von Stetten, D, Essen, L.-O. | Deposit date: | 2013-07-03 | Release date: | 2013-10-30 | Last modified: | 2019-05-08 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structure of the Cyanobacterial Phytochrome 2 Photosensor Implies a Tryptophan Switch for Phytochrome Signaling. J.Biol.Chem., 288, 2013
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2Y79
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![BU of 2y79 by Molmil](/molmil-images/mine/2y79) | STRUCTURE OF THE FIRST GAF DOMAIN E87A MUTANT OF MYCOBACTERIUM TUBERCULOSIS DOSS | Descriptor: | CALCIUM ION, GLYCEROL, PROTOPORPHYRIN IX CONTAINING FE, ... | Authors: | Cho, H.Y, Cho, H.J, Kang, B.S. | Deposit date: | 2011-01-30 | Release date: | 2011-02-16 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Blockage of the Channel to Heme by the E87 Side Chain in the Gaf Domain of Mycobacterium Tuberculosis Doss Confers the Unique Sensitivity of Doss to Oxygen. FEBS Lett., 585, 2011
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2XSS
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![BU of 2xss by Molmil](/molmil-images/mine/2xss) | |
2Y8H
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8W26
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![BU of 8w26 by Molmil](/molmil-images/mine/8w26) | |
3KO6
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![BU of 3ko6 by Molmil](/molmil-images/mine/3ko6) | |
3P01
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4G3K
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![BU of 4g3k by Molmil](/molmil-images/mine/4g3k) | Crystal structure of a. aeolicus nlh1 gaf domain in an inactive state | Descriptor: | Transcriptional regulator nlh1 | Authors: | Wemmer, D.E, Batchelor, J.D, Wang, A, Lee, P, Doucleff, M. | Deposit date: | 2012-07-14 | Release date: | 2013-05-29 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (3.05 Å) | Cite: | Structural mechanism of GAF-regulated delta(54) activators from Aquifex aeolicus J.Mol.Biol., 425, 2013
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4G3W
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![BU of 4g3w by Molmil](/molmil-images/mine/4g3w) | Crystal structure of a. aeolicus nlh1 gaf domain in an inactive state | Descriptor: | Transcriptional regulator nlh1 | Authors: | Batchelor, J.D, Wang, A, Lee, P, Doucleff, M, Wemmer, D.E. | Deposit date: | 2012-07-15 | Release date: | 2013-05-29 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural mechanism of GAF-regulated delta(54) activators from Aquifex aeolicus J.Mol.Biol., 425, 2013
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