1K5W
| THREE-DIMENSIONAL STRUCTURE OF THE SYNAPTOTAGMIN 1 C2B-DOMAIN: SYNAPTOTAGMIN 1 AS A PHOSPHOLIPID BINDING MACHINE | Descriptor: | CALCIUM ION, Synaptotagmin I | Authors: | Fernandez, I, Arac, D, Ubach, J, Gerber, S.H, Shin, O, Gao, Y, Anderson, R.G.W, Sudhof, T.C, Rizo, J. | Deposit date: | 2001-10-12 | Release date: | 2002-01-23 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Three-dimensional structure of the synaptotagmin 1 C2B-domain: synaptotagmin 1 as a phospholipid binding machine. Neuron, 32, 2001
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4DNL
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7JOF
| Calcium-bound C2A Domain from Human Dysferlin | Descriptor: | CALCIUM ION, Isoform 6 of Dysferlin | Authors: | Tadayon, R, Wang, Y, Santamaria, L, Mercier, P, Forristal, C, Shaw, G.S. | Deposit date: | 2020-08-06 | Release date: | 2021-06-16 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Calcium binds and rigidifies the dysferlin C2A domain in a tightly coupled manner. Biochem.J., 478, 2021
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4WEE
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7K6B
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7KRB
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4Y1S
| Structural basis for Ca2+-mediated interaction of the perforin C2 domain with lipid membranes | Descriptor: | CALCIUM ION, Perforin-1 | Authors: | Conroy, P.J, Yagi, H, Whisstock, J.C, Norton, R.S. | Deposit date: | 2015-02-09 | Release date: | 2015-09-02 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.611 Å) | Cite: | Structural Basis for Ca2+-mediated Interaction of the Perforin C2 Domain with Lipid Membranes. J.Biol.Chem., 290, 2015
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5H4Z
| Crystal structure of S202G mutant of human SYT-5 C2A domain | Descriptor: | CALCIUM ION, CHLORIDE ION, Synaptotagmin-5 | Authors: | Qiu, X, Ge, J, Yan, X, Gao, Y, Teng, M, Niu, L. | Deposit date: | 2016-11-02 | Release date: | 2016-11-30 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (3.01 Å) | Cite: | Structural analysis of Ca(2+)-binding pocket of synaptotagmin 5 C2A domain Int. J. Biol. Macromol., 95, 2017
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5H4Y
| Crystal structure of human synaptotagmin 5 C2A domain | Descriptor: | ACETATE ION, CALCIUM ION, Synaptotagmin-5 | Authors: | Qiu, X, Gao, Y, Teng, M, Niu, L. | Deposit date: | 2016-11-02 | Release date: | 2016-11-30 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural analysis of Ca(2+)-binding pocket of synaptotagmin 5 C2A domain Int. J. Biol. Macromol., 95, 2017
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4TS6
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7U4Q
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7TX9
| Human Synaptotagmin-1 C2B Y312F Ca2+ bound | Descriptor: | 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, CALCIUM ION, CHLORIDE ION, ... | Authors: | Dominguez, M.J, Karmakar, S, Fuson, K.L, Sutton, R.B. | Deposit date: | 2022-02-08 | Release date: | 2023-03-29 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.34 Å) | Cite: | Human Synaptotagmin-1 C2B Y312F Ca2+ bound To Be Published
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1A25
| C2 DOMAIN FROM PROTEIN KINASE C (BETA) | Descriptor: | CALCIUM ION, O-PHOSPHOETHANOLAMINE, PROTEIN KINASE C (BETA) | Authors: | Sutton, R.B, Sprang, S.R. | Deposit date: | 1998-01-16 | Release date: | 1998-05-06 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structure of the protein kinase Cbeta phospholipid-binding C2 domain complexed with Ca2+. Structure, 6, 1998
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7TUA
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3TWY
| RAT PKC C2 DOMAIN BOUND TO PB | Descriptor: | LEAD (II) ION, Protein kinase C alpha type, SULFATE ION | Authors: | Li, P. | Deposit date: | 2011-09-22 | Release date: | 2011-11-02 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Pb2+ as Modulator of Protein-Membrane Interactions. J.Am.Chem.Soc., 133, 2011
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4V11
| Structure of Synaptotagmin-1 with SV2A peptide phosphorylated at Thr84 | Descriptor: | CALCIUM ION, GLYCEROL, SYNAPTIC VESICLE GLYCOPROTEIN 2A, ... | Authors: | Zhang, N, Gordon, S.L, Fritsch, M.J, Esoof, N, Campbell, D, Gourlay, R, Velupillai, S, Macartney, T, Peggie, M, vanAalten, D.M.F, Cousin, M.A, Alessi, D.R. | Deposit date: | 2014-09-22 | Release date: | 2015-02-25 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Phosphorylation of Synaptic Vesicle Protein 2A at Thr84 by Casein Kinase 1 Family Kinases Controls the Specific Retrieval of Synaptotagmin-1. J.Neurosci., 35, 2015
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1BCI
| C2 DOMAIN OF CYTOSOLIC PHOSPHOLIPASE A2, NMR, MINIMIZED AVERAGE STRUCTURE | Descriptor: | CALCIUM ION, CYTOSOLIC PHOSPHOLIPASE A2 | Authors: | Xu, G.Y, Mcdonagh, T, Yu, H.A, Nalefski, E.A, Clark, J.D, Cumming, D.A. | Deposit date: | 1998-04-30 | Release date: | 1998-11-25 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Solution structure and membrane interactions of the C2 domain of cytosolic phospholipase A2. J.Mol.Biol., 280, 1998
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4V29
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1BYN
| SOLUTION STRUCTURE OF THE CALCIUM-BOUND FIRST C2-DOMAIN OF SYNAPTOTAGMIN I | Descriptor: | CALCIUM ION, PROTEIN (SYNAPTOTAGMIN I) | Authors: | Shao, X, Fernandez, I, Sudhof, T.C, Rizo, J. | Deposit date: | 1998-10-18 | Release date: | 1998-10-21 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Solution structures of the Ca2+-free and Ca2+-bound C2A domain of synaptotagmin I: does Ca2+ induce a conformational change? Biochemistry, 37, 1998
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2YOA
| Synaptotagmin-1 C2B domain with phosphoserine | Descriptor: | CALCIUM ION, PHOSPHOSERINE, SYNAPTOTAGMIN-1, ... | Authors: | Honigmann, A, van den Bogaart, G, Iraheta, E, Risselada, H.J, Milovanovic, D, Mueller, V, Muellar, S, Diederichsen, U, Fasshauer, D, Grubmuller, H, Hell, S.W, Eggeling, C, Kuhnel, K, Jahn, R. | Deposit date: | 2012-10-22 | Release date: | 2013-03-20 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Phosphatidylinositol 4,5-Bisphosphate Clusters Act as Molecular Beacons for Vesicle Recruitment Nat.Struct.Mol.Biol., 20, 2013
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2Z0U
| Crystal structure of C2 domain of KIBRA protein | Descriptor: | WW domain-containing protein 1 | Authors: | Murayama, K, Kato-Murayama, M, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2007-05-07 | Release date: | 2008-05-13 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structure of C2 domain of KIBRA protein To be Published
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3W56
| Structure of a C2 domain | Descriptor: | C2 domain protein | Authors: | Traore, D.A.K, Whisstock, J.C. | Deposit date: | 2013-01-24 | Release date: | 2013-10-23 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Defining the interaction of perforin with calcium and the phospholipid membrane. Biochem.J., 456, 2013
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3W57
| Structure of a C2 domain | Descriptor: | C2 domain protein, CALCIUM ION | Authors: | Traore, D.A.K, Whisstock, J.C. | Deposit date: | 2013-01-24 | Release date: | 2013-10-23 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.662 Å) | Cite: | Defining the interaction of perforin with calcium and the phospholipid membrane. Biochem.J., 456, 2013
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3HN8
| Crystal structure of synaptotagmin | Descriptor: | CALCIUM ION, Synaptotagmin-3, ZINC ION | Authors: | Strop, P, Vrljic, M, Ernst, J, Brunger, A.T. | Deposit date: | 2009-05-30 | Release date: | 2010-02-23 | Last modified: | 2017-11-01 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Molecular mechanism of the synaptotagmin-SNARE interaction in Ca2+-triggered vesicle fusion. Nat.Struct.Mol.Biol., 17, 2010
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7A1R
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