3L9B

Crystal Structure of Rat Otoferlin C2A

Summary for 3L9B

Entry DOI	10.2210/pdb3l9b/pdb
Descriptor	Otoferlin, MAGNESIUM ION (3 entities in total)
Functional Keywords	otoferlin, c2-domain, beta-sheets, cell membrane, synaptic vesicle, hearing, membrane, synapse, transmembrane, membrane protein
Biological source	Rattus norvegicus (rat)
Cellular location	Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Single-pass type II membrane protein (By similarity): Q9ERC5
Total number of polymer chains	1
Total formula weight	16436.82
Authors	Helfmann, S.,Neumann, P. (deposition date: 2010-01-04, release date: 2011-01-19, Last modification date: 2023-11-01)
Primary citation	Helfmann, S.,Neumann, P.,Tittmann, K.,Moser, T.,Ficner, R.,Reisinger, E. The crystal structure of the C2A domain of otoferlin reveals an unconventional top loop region. J.Mol.Biol., 406:479-490, 2011 Cited by PubMed: 21216247 DOI: 10.1016/j.jmb.2010.12.031 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.95 Å)

Structure validation