6NJX
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![BU of 6njx by Molmil](/molmil-images/mine/6njx) | C-terminal region of the Xanthomonas campestris pv. campestris OLD protein phased with mercury | Descriptor: | IODIDE ION, MERCURY (II) ION, Xcc_ctr_Hg | Authors: | Schiltz, C.J, Lee, A, Partlow, E.A, Hosford, C.J, Chappie, J.S. | Deposit date: | 2019-01-04 | Release date: | 2019-08-07 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Structural characterization of Class 2 OLD family nucleases supports a two-metal catalysis mechanism for cleavage. Nucleic Acids Res., 47, 2019
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6NK8
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![BU of 6nk8 by Molmil](/molmil-images/mine/6nk8) | C-terminal region of the Burkholderia pseudomallei OLD protein | Descriptor: | Class 2 OLD family nuclease, MAGNESIUM ION | Authors: | Schiltz, C.J, Lee, A, Partlow, E.A, Hosford, C.J, Chappie, J.S. | Deposit date: | 2019-01-05 | Release date: | 2019-08-07 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.24 Å) | Cite: | Structural characterization of Class 2 OLD family nucleases supports a two-metal catalysis mechanism for cleavage. Nucleic Acids Res., 47, 2019
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6NJW
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![BU of 6njw by Molmil](/molmil-images/mine/6njw) | C-terminal region of the Xanthomonas campestris pv. campestris OLD protein phased with platinum | Descriptor: | IODIDE ION, MAGNESIUM ION, PLATINUM (II) ION, ... | Authors: | Schiltz, C.J, Lee, A, Partlow, E.A, Hosford, C.J, Chappie, J.S. | Deposit date: | 2019-01-04 | Release date: | 2019-08-07 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.86 Å) | Cite: | Structural characterization of Class 2 OLD family nucleases supports a two-metal catalysis mechanism for cleavage. Nucleic Acids Res., 47, 2019
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6NJV
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![BU of 6njv by Molmil](/molmil-images/mine/6njv) | C-terminal region of the Xanthomonas campestris pv. campestris OLD protein phased with iodine | Descriptor: | IODIDE ION, MAGNESIUM ION, Xcc_CTR_I | Authors: | Schiltz, C.J, Lee, A, Partlow, E.A, Hosford, C.J, Chappie, J.S. | Deposit date: | 2019-01-04 | Release date: | 2019-08-07 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural characterization of Class 2 OLD family nucleases supports a two-metal catalysis mechanism for cleavage. Nucleic Acids Res., 47, 2019
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8DXA
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![BU of 8dxa by Molmil](/molmil-images/mine/8dxa) | [C:Hg2+/Ag+:C--pH 7] Metal-mediated DNA base pair in tensegrity triangle in Ag+ and Hg2+ solution | Descriptor: | DNA (5'-D(*GP*AP*GP*CP*AP*GP*CP*CP*TP*GP*TP*CP*TP*GP*GP*AP*CP*AP*TP*CP*A)-3'), DNA (5'-D(P*CP*CP*AP*CP*AP*CP*A)-3'), DNA (5'-D(P*CP*TP*GP*AP*TP*GP*T)-3'), ... | Authors: | Lu, B, Vecchioni, S, Seeman, N.C, Sha, R, Ohayon, Y.P. | Deposit date: | 2022-08-02 | Release date: | 2023-08-09 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (4.21 Å) | Cite: | Heterobimetallic Base Pair Programming in Designer 3D DNA Crystals. J.Am.Chem.Soc., 145, 2023
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8DXF
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![BU of 8dxf by Molmil](/molmil-images/mine/8dxf) | [C:Hg2+/Ag+:C--pH 9] Metal-mediated DNA base pair in tensegrity triangle in Ag+ and Hg2+ solution | Descriptor: | DNA (5'-D(*GP*AP*GP*CP*AP*GP*CP*CP*TP*GP*TP*CP*TP*GP*GP*AP*CP*AP*TP*CP*A)-3'), DNA (5'-D(P*CP*CP*AP*CP*AP*CP*A)-3'), DNA (5'-D(P*CP*TP*GP*AP*TP*GP*T)-3'), ... | Authors: | Lu, B, Vecchioni, S, Seeman, N.C, Sha, R, Ohayon, Y.P. | Deposit date: | 2022-08-02 | Release date: | 2023-08-09 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (4.29 Å) | Cite: | Heterobimetallic Base Pair Programming in Designer 3D DNA Crystals. J.Am.Chem.Soc., 145, 2023
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8DX7
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![BU of 8dx7 by Molmil](/molmil-images/mine/8dx7) | [C:Hg2+/Ag+:C--pH 6] Metal-mediated DNA base pair in tensegrity triangle in Ag+ and Hg2+ solution | Descriptor: | DNA (5'-D(*GP*AP*GP*CP*AP*GP*CP*CP*TP*GP*TP*CP*TP*GP*GP*AP*CP*AP*TP*CP*A)-3'), DNA (5'-D(P*CP*CP*AP*CP*AP*CP*A)-3'), DNA (5'-D(P*CP*TP*GP*AP*TP*GP*T)-3'), ... | Authors: | Lu, B, Vecchioni, S, Seeman, N.C, Sha, R, Ohayon, Y.P. | Deposit date: | 2022-08-02 | Release date: | 2023-08-09 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (4.92 Å) | Cite: | Heterobimetallic Base Pair Programming in Designer 3D DNA Crystals. J.Am.Chem.Soc., 145, 2023
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8DXC
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![BU of 8dxc by Molmil](/molmil-images/mine/8dxc) | [C:Hg2+/Ag+:C--pH 7.5] Metal-mediated DNA base pair in tensegrity triangle in Ag+ and Hg2+ solution | Descriptor: | DNA (5'-D(*GP*AP*GP*CP*AP*GP*CP*CP*TP*GP*TP*CP*TP*GP*GP*AP*CP*AP*TP*CP*A)-3'), DNA (5'-D(P*CP*CP*AP*CP*AP*CP*A)-3'), DNA (5'-D(P*CP*TP*GP*AP*TP*GP*T)-3'), ... | Authors: | Lu, B, Vecchioni, S, Seeman, N.C, Sha, R, Ohayon, Y.P. | Deposit date: | 2022-08-02 | Release date: | 2023-08-09 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (5.04 Å) | Cite: | Heterobimetallic Base Pair Programming in Designer 3D DNA Crystals. J.Am.Chem.Soc., 145, 2023
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8DX5
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![BU of 8dx5 by Molmil](/molmil-images/mine/8dx5) | [C:Hg2+/Ag+:C--pH 5] Metal-mediated DNA base pair in tensegrity triangle in Ag+ and Hg2+ solution | Descriptor: | DNA (5'-D(*GP*AP*GP*CP*AP*GP*CP*CP*TP*GP*TP*CP*TP*GP*GP*AP*CP*AP*TP*CP*A)-3'), DNA (5'-D(P*CP*CP*AP*CP*AP*CP*A)-3'), DNA (5'-D(P*CP*TP*GP*AP*TP*GP*T)-3'), ... | Authors: | Lu, B, Vecchioni, S, Seeman, N.C, Sha, R, Ohayon, Y.P. | Deposit date: | 2022-08-02 | Release date: | 2023-08-09 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (5.9 Å) | Cite: | Heterobimetallic Base Pair Programming in Designer 3D DNA Crystals. J.Am.Chem.Soc., 145, 2023
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8DX9
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![BU of 8dx9 by Molmil](/molmil-images/mine/8dx9) | [C:Hg2+/Ag+:C--pH 6.5] Metal-mediated DNA base pair in tensegrity triangle in Ag+ and Hg2+ solution | Descriptor: | DNA (5'-D(*GP*AP*GP*CP*AP*GP*CP*CP*TP*GP*TP*CP*TP*GP*GP*AP*CP*AP*TP*CP*A)-3'), DNA (5'-D(P*CP*CP*AP*CP*AP*CP*A)-3'), DNA (5'-D(P*CP*TP*GP*AP*TP*GP*T)-3'), ... | Authors: | Lu, B, Vecchioni, S, Seeman, N.C, Sha, R, Ohayon, Y.P. | Deposit date: | 2022-08-02 | Release date: | 2023-08-09 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (4.55 Å) | Cite: | Heterobimetallic Base Pair Programming in Designer 3D DNA Crystals. J.Am.Chem.Soc., 145, 2023
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8DXD
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![BU of 8dxd by Molmil](/molmil-images/mine/8dxd) | [C:Hg2+/Ag+:C--pH 8] Metal-mediated DNA base pair in tensegrity triangle in Ag+ and Hg2+ solution | Descriptor: | DNA (5'-D(*GP*AP*GP*CP*AP*GP*CP*CP*TP*GP*TP*CP*TP*GP*GP*AP*CP*AP*TP*CP*A)-3'), DNA (5'-D(P*CP*CP*AP*CP*AP*CP*A)-3'), DNA (5'-D(P*CP*TP*GP*AP*TP*GP*T)-3'), ... | Authors: | Lu, B, Vecchioni, S, Seeman, N.C, Sha, R, Ohayon, Y.P. | Deposit date: | 2022-08-02 | Release date: | 2023-08-09 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (4.28 Å) | Cite: | Heterobimetallic Base Pair Programming in Designer 3D DNA Crystals. J.Am.Chem.Soc., 145, 2023
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8DX1
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![BU of 8dx1 by Molmil](/molmil-images/mine/8dx1) | [C:Hg2+/Ag+:C--pH 7 MOPS] Metal-mediated DNA base pair in tensegrity triangle in Ag+ and Hg2+ solution in MOPS | Descriptor: | DNA (5'-D(*GP*AP*GP*CP*AP*GP*CP*CP*TP*GP*TP*CP*TP*GP*GP*AP*CP*AP*TP*CP*A)-3'), DNA (5'-D(P*CP*CP*AP*CP*AP*CP*A)-3'), DNA (5'-D(P*CP*TP*GP*AP*TP*GP*T)-3'), ... | Authors: | Lu, B, Vecchioni, S, Seeman, N.C, Sha, R, Ohayon, Y.P. | Deposit date: | 2022-08-02 | Release date: | 2023-08-09 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (4.79 Å) | Cite: | Heterobimetallic Base Pair Programming in Designer 3D DNA Crystals. J.Am.Chem.Soc., 145, 2023
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8DX6
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![BU of 8dx6 by Molmil](/molmil-images/mine/8dx6) | [C:Hg2+/Ag+:C--pH 5.5] Metal-mediated DNA base pair in tensegrity triangle in Ag+ and Hg2+ solution | Descriptor: | DNA (5'-D(*GP*AP*GP*CP*AP*GP*CP*CP*TP*GP*TP*CP*TP*GP*GP*AP*CP*AP*TP*CP*A)-3'), DNA (5'-D(P*CP*CP*AP*CP*AP*CP*A)-3'), DNA (5'-D(P*CP*TP*GP*AP*TP*GP*T)-3'), ... | Authors: | Lu, B, Vecchioni, S, Seeman, N.C, Sha, R, Ohayon, Y.P. | Deposit date: | 2022-08-02 | Release date: | 2023-08-09 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (5.34 Å) | Cite: | Heterobimetallic Base Pair Programming in Designer 3D DNA Crystals. J.Am.Chem.Soc., 145, 2023
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4U5J
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![BU of 4u5j by Molmil](/molmil-images/mine/4u5j) | C-Src in complex with Ruxolitinib | Descriptor: | (3R)-3-cyclopentyl-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl]propanenitrile, Proto-oncogene tyrosine-protein kinase Src | Authors: | Chen, Y, Duan, Y, Chen, L. | Deposit date: | 2014-07-25 | Release date: | 2014-09-17 | Last modified: | 2024-06-26 | Method: | X-RAY DIFFRACTION (2.26 Å) | Cite: | c-Src Binds to the Cancer Drug Ruxolitinib with an Active Conformation Plos One, 9, 2014
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6GYZ
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![BU of 6gyz by Molmil](/molmil-images/mine/6gyz) | |
8OSE
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![BU of 8ose by Molmil](/molmil-images/mine/8ose) | C. perfringens chitinase CP4_3455 in complex with inhibitor bisdionin C | Descriptor: | 1,1'-PROPANE-1,3-DIYLBIS(3,7-DIMETHYL-3,7-DIHYDRO-1H-PURINE-2,6-DIONE), 1,2-ETHANEDIOL, Chitodextrinase, ... | Authors: | Bloch, Y, Savvides, S.N. | Deposit date: | 2023-04-18 | Release date: | 2023-07-12 | Last modified: | 2024-06-19 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | C. perfringens chitinase CP4_3455 in complex with inhibitor bisdionin C To Be Published
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7VE5
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![BU of 7ve5 by Molmil](/molmil-images/mine/7ve5) | C-terminal domain of VraR | Descriptor: | DNA-binding response regulator, MAGNESIUM ION, R1-DNA | Authors: | Kumar, J.V, Chen, C, Hsu, C.H. | Deposit date: | 2021-09-08 | Release date: | 2022-05-18 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural insights into DNA binding domain of vancomycin-resistance-associated response regulator in complex with its promoter DNA from Staphylococcus aureus. Protein Sci., 31, 2022
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6XIY
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![BU of 6xiy by Molmil](/molmil-images/mine/6xiy) | Crystal Structure of the Carbohydrate Recognition Domain of the Human Macrophage Galactose C-Type Lectin Bound to methyl 2-(acetylamino)-2-deoxy-1-thio-alpha-D-galactopyranose | Descriptor: | C-type lectin domain family 10 member A, CALCIUM ION, CHLORIDE ION, ... | Authors: | Birrane, G, Murphy, P.V, Gabba, A, Luz, J.G. | Deposit date: | 2020-06-22 | Release date: | 2021-03-31 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.307 Å) | Cite: | Crystal Structure of the Carbohydrate Recognition Domain of the Human Macrophage Galactose C-Type Lectin Bound to GalNAc and the Tumor-Associated Tn Antigen. Biochemistry, 60, 2021
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7SD7
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![BU of 7sd7 by Molmil](/molmil-images/mine/7sd7) | [C:Hg2+:T] Metal-mediated DNA base pair in a self-assembling rhombohedral lattice | Descriptor: | DNA (5'-D(*GP*AP*GP*CP*AP*GP*CP*CP*TP*GP*TP*CP*TP*GP*GP*AP*CP*AP*TP*CP*A)-3'), DNA (5'-D(*TP*CP*TP*GP*AP*TP*GP*T)-3'), DNA (5'-D(P*CP*CP*AP*TP*AP*CP*A)-3'), ... | Authors: | Vecchioni, S, Lu, B, Seeman, N.C, Sha, R, Ohayon, Y.P. | Deposit date: | 2021-09-29 | Release date: | 2022-10-05 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (3.68 Å) | Cite: | Metal-Mediated DNA Nanotechnology in 3D: Structural Library by Templated Diffraction. Adv Mater, 2023
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8FK8
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![BU of 8fk8 by Molmil](/molmil-images/mine/8fk8) | Crystal Structure of the Tick Evasin EVA-AAM1001(L39P) Complexed to Human Chemokine CCL7 | Descriptor: | C-C motif chemokine 7, Evasin P1243 | Authors: | Devkota, S.R, Bhusal, R.P, Aryal, P, Wilce, M.C.J, Stone, M.J. | Deposit date: | 2022-12-20 | Release date: | 2023-03-29 | Last modified: | 2023-07-26 | Method: | X-RAY DIFFRACTION (1.96 Å) | Cite: | Engineering broad-spectrum inhibitors of inflammatory chemokines from subclass A3 tick evasins. Nat Commun, 14, 2023
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8FK6
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![BU of 8fk6 by Molmil](/molmil-images/mine/8fk6) | Crystal Structure of the Tick Evasin EVA-AAM1001(Y44A) Complexed to Human Chemokine CCL7 | Descriptor: | C-C motif chemokine 7, Evasin P1243 | Authors: | Devkota, S.R, Bhusal, R.P, Aryal, P, Wilce, M.C.J, Stone, M.J. | Deposit date: | 2022-12-20 | Release date: | 2023-03-29 | Last modified: | 2023-08-02 | Method: | X-RAY DIFFRACTION (1.74 Å) | Cite: | Engineering broad-spectrum inhibitors of inflammatory chemokines from subclass A3 tick evasins. Nat Commun, 14, 2023
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8FJ2
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![BU of 8fj2 by Molmil](/molmil-images/mine/8fj2) | Crystal Structure of the Tick Evasin EVA-AAM1001(C8) Complexed to Human Chemokine CCL17 | Descriptor: | C-C motif chemokine 17, Evasin P1243 | Authors: | Devkota, S.R, Bhusal, R.P, Aryal, P, Wilce, M.C.J, Stone, M.J. | Deposit date: | 2022-12-19 | Release date: | 2023-03-29 | Last modified: | 2023-07-26 | Method: | X-RAY DIFFRACTION (2.07 Å) | Cite: | Engineering broad-spectrum inhibitors of inflammatory chemokines from subclass A3 tick evasins. Nat Commun, 14, 2023
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8JAH
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![BU of 8jah by Molmil](/molmil-images/mine/8jah) | Crystal structure of human CLEC12A C-type lectin domain | Descriptor: | C-type lectin domain family 12 member A, POTASSIUM ION, SULFATE ION | Authors: | Lei, Q, Tang, H, Dong, X. | Deposit date: | 2023-05-06 | Release date: | 2024-03-13 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.58 Å) | Cite: | Mechanistic insights into the C-type lectin receptor CLEC12A-mediated immune recognition of monosodium urate crystal. J.Biol.Chem., 300, 2024
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1BV4
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![BU of 1bv4 by Molmil](/molmil-images/mine/1bv4) | APO-MANNOSE-BINDING PROTEIN-C | Descriptor: | PROTEIN (MANNOSE-BINDING PROTEIN-C) | Authors: | Ng, K.K.-S, Weis, W.I. | Deposit date: | 1998-09-22 | Release date: | 1999-01-13 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Ca2+-dependent structural changes in C-type mannose-binding proteins. Biochemistry, 37, 1998
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8D4Y
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![BU of 8d4y by Molmil](/molmil-images/mine/8d4y) | C-terminal SANT-SLIDE domain of human Chromodomain-helicase-DNA-binding protein 4 (CHD4) | Descriptor: | Chromodomain-helicase-DNA-binding protein 4 | Authors: | Moghaddas Sani, H, Deshpande, C.N, Panjikar, S, Patel, K, Mackay, J.P. | Deposit date: | 2022-06-03 | Release date: | 2022-12-21 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | The role of auxiliary domains in modulating CHD4 activity suggests mechanistic commonality between enzyme families. Nat Commun, 13, 2022
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