4KIB

Crystal structure of methyltransferase from Streptomyces hygroscopicus complexed with S-adenosyl-L-homocysteine and methylphenylpyruvic acid

Summary for 4KIB

Entry DOI	10.2210/pdb4kib/pdb
Related	4M6X 4M6Y 4M71 4M72 4M73 4M74 4kic 4kif 4kig
Descriptor	Methyltransferase MppJ, S-ADENOSYL-L-HOMOCYSTEINE, (3R)-2-oxo-3-phenylbutanoic acid, ... (7 entities in total)
Functional Keywords	rossmann fold, methyltransferase, sam binding ppy binding, transferase
Biological source	Streptomyces hygroscopicus
Total number of polymer chains	2
Total formula weight	81414.30
Authors	Liu, Y.C.,Zou, X.W.,Chan, H.C.,Huang, C.J.,Li, T.L. (deposition date: 2013-05-02, release date: 2014-05-07, Last modification date: 2023-11-15)
Primary citation	Zou, X.W.,Liu, Y.C.,Hsu, N.S.,Huang, C.J.,Lyu, S.Y.,Chan, H.C.,Chang, C.Y.,Yeh, H.W.,Lin, K.H.,Wu, C.J.,Tsai, M.D.,Li, T.L. Structure and mechanism of a nonhaem-iron SAM-dependent C-methyltransferase and its engineering to a hydratase and an O-methyltransferase Acta Crystallogr.,Sect.D, 70:1549-1560, 2014 Cited by PubMed: 24914966 DOI: 10.1107/S1399004714005239 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation