1FXH
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![BU of 1fxh by Molmil](/molmil-images/mine/1fxh) | MUTANT OF PENICILLIN ACYLASE IMPAIRED IN CATALYSIS WITH PHENYLACETIC ACID IN THE ACTIVE SITE | Descriptor: | 2-PHENYLACETIC ACID, CALCIUM ION, PENICILLIN ACYLASE | Authors: | Alkema, W.B, Hensgens, C.M, Kroezinga, E.H, de Vries, E, Floris, R, van der Laan, J.M, Dijkstra, B.W, Janssen, D.B. | Deposit date: | 2000-09-26 | Release date: | 2001-03-28 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.97 Å) | Cite: | Characterization of the beta-lactam binding site of penicillin acylase of Escherichia coli by structural and site-directed mutagenesis studies. Protein Eng., 13, 2000
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1FYZ
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![BU of 1fyz by Molmil](/molmil-images/mine/1fyz) | METHANE MONOOXYGENASE HYDROXYLASE, FORM II REDUCED BY SOAKING | Descriptor: | CALCIUM ION, FE (II) ION, METHANE MONOOXYGENASE COMPONENT A, ... | Authors: | Whittington, D.A, Lippard, S.J. | Deposit date: | 2000-10-03 | Release date: | 2001-02-21 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Crystal structures of the soluble methane monooxygenase hydroxylase from Methylococcus capsulatus (Bath) demonstrating geometrical variability at the dinuclear iron active site. J.Am.Chem.Soc., 123, 2001
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1FZH
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![BU of 1fzh by Molmil](/molmil-images/mine/1fzh) | METHANE MONOOXYGENASE HYDROXYLASE, FORM II PRESSURIZED WITH XENON GAS | Descriptor: | CALCIUM ION, FE (III) ION, METHANE MONOOXYGENASE COMPONENT A, ... | Authors: | Whittington, D.A, Rosenzweig, A.C, Frederick, C.A, Lippard, S.J. | Deposit date: | 2000-10-03 | Release date: | 2001-04-27 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Xenon and halogenated alkanes track putative substrate binding cavities in the soluble methane monooxygenase hydroxylase. Biochemistry, 40, 2001
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4WZ7
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![BU of 4wz7 by Molmil](/molmil-images/mine/4wz7) | Crystal structure of mitochondrial NADH:ubiquinone oxidoreductase from Yarrowia lipolytica. | Descriptor: | 39-kDa subunit, FE2/S2 (INORGANIC) CLUSTER, IRON/SULFUR CLUSTER, ... | Authors: | Wirth, C, Zickermann, V, Brandt, U, Hunte, C. | Deposit date: | 2014-11-18 | Release date: | 2015-03-25 | Method: | X-RAY DIFFRACTION (3.6 Å) | Cite: | Structural biology. Mechanistic insight from the crystal structure of mitochondrial complex I. Science, 347, 2015
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1SEV
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![BU of 1sev by Molmil](/molmil-images/mine/1sev) | Mature and translocatable forms of glyoxysomal malate dehydrogenase have different activities and stabilities but similar crystal structures | Descriptor: | Malate dehydrogenase, glyoxysomal precursor | Authors: | Cox, B.R, Chit, M.M, Weaver, T.M, Bailey, J, Gietl, C, Bell, E, Banaszak, L.J. | Deposit date: | 2004-02-18 | Release date: | 2005-01-25 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Organelle and translocatable forms of glyoxysomal malate dehydrogenase. The effect of the N-terminal presequence Febs J., 272, 2005
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1G0S
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![BU of 1g0s by Molmil](/molmil-images/mine/1g0s) | |
1SFG
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![BU of 1sfg by Molmil](/molmil-images/mine/1sfg) | BINDING OF HEXA-N-ACETYLCHITOHEXAOSE: A POWDER DIFFRACTION STUDY | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, LYSOZYME | Authors: | Von Dreele, R.B. | Deposit date: | 2004-02-19 | Release date: | 2004-03-02 | Last modified: | 2020-07-29 | Method: | POWDER DIFFRACTION | Cite: | Binding of N-acetylglucosamine oligosaccharides to hen egg-white lysozyme: a powder diffraction study. Acta Crystallogr.,Sect.D, 61, 2005
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7F8D
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![BU of 7f8d by Molmil](/molmil-images/mine/7f8d) | Malate Dehydrogenase from Geobacillus stearothermophilus (gs-MDH) G218Y mutant | Descriptor: | Malate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | Authors: | Shimozawa, Y, Himiyama, T, Nakamura, T, Nishiya, Y. | Deposit date: | 2021-07-02 | Release date: | 2022-02-23 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Increasing loop flexibility affords low-temperature adaptation of a moderate thermophilic malate dehydrogenase from Geobacillus stearothermophilus. Protein Eng.Des.Sel., 34, 2021
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3OIC
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![BU of 3oic by Molmil](/molmil-images/mine/3oic) | Crystal Structure of Enoyl-ACP Reductases III (FabL) from B. subtilis (apo form) | Descriptor: | Enoyl-[acyl-carrier-protein] reductase [NADPH], SULFATE ION | Authors: | Kim, K.-H, Ha, B.H, Kim, S.J, Hong, S.K, Hwang, K.Y, Kim, E.E. | Deposit date: | 2010-08-19 | Release date: | 2011-01-05 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal Structures of Enoyl-ACP Reductases I (FabI) and III (FabL) from B. subtilis J.Mol.Biol., 406, 2011
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4WTV
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![BU of 4wtv by Molmil](/molmil-images/mine/4wtv) | Crystal structure of the phosphatidylinositol 4-kinase IIbeta | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Phosphatidylinositol 4-kinase type 2-beta,Endolysin,Phosphatidylinositol 4-kinase type 2-beta | Authors: | Klima, M, Baumlova, A, Chalupska, D, Boura, E. | Deposit date: | 2014-10-30 | Release date: | 2015-07-15 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | The high-resolution crystal structure of phosphatidylinositol 4-kinase II beta and the crystal structure of phosphatidylinositol 4-kinase II alpha containing a nucleoside analogue provide a structural basis for isoform-specific inhibitor design. Acta Crystallogr.,Sect.D, 71, 2015
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1S3T
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![BU of 1s3t by Molmil](/molmil-images/mine/1s3t) | BORATE INHIBITED BACILLUS PASTEURII UREASE CRYSTAL STRUCTURE | Descriptor: | BORIC ACID, NICKEL (II) ION, SULFATE ION, ... | Authors: | Benini, S, Rypniewski, W.R, Wilson, K.S, Ciurli, S, Mangani, S. | Deposit date: | 2004-01-14 | Release date: | 2004-04-06 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Molecular Details of Urease Inhibition by Boric Acid: Insights into the Catalytic Mechanism. J.Am.Chem.Soc., 126, 2004
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3OJ4
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3OJX
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![BU of 3ojx by Molmil](/molmil-images/mine/3ojx) | Disulfide crosslinked cytochrome P450 reductase inactive | Descriptor: | FLAVIN MONONUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | Authors: | Xia, C, Hamdane, D, Shen, A, Choi, V, Kasper, C, Zhang, H, Im, S.-C, Waskell, L, Kim, J.-J.P. | Deposit date: | 2010-08-23 | Release date: | 2011-02-23 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Conformational Changes of NADPH-Cytochrome P450 Oxidoreductase Are Essential for Catalysis and Cofactor Binding. J.Biol.Chem., 286, 2011
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4X3B
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![BU of 4x3b by Molmil](/molmil-images/mine/4x3b) | A micro-patterned silicon chip as sample holder for macromolecular crystallography experiments with minimal background scattering | Descriptor: | CHLORIDE ION, Lysozyme C, SODIUM ION | Authors: | Roedig, P, Vartiainen, I, Duman, R, Panneerselvam, S, Stuebe, N, Lorbeer, O, Warmer, M, Sutton, G, Stuart, D.I, Weckert, E, David, C, Wagner, A, Meents, A. | Deposit date: | 2014-11-28 | Release date: | 2015-06-10 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | A micro-patterned silicon chip as sample holder for macromolecular crystallography experiments with minimal background scattering. Sci Rep, 5, 2015
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1GK0
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![BU of 1gk0 by Molmil](/molmil-images/mine/1gk0) | Structure-based prediction of modifications in glutarylamidase to allow single-step enzymatic production of 7-aminocephalosporanic acid from cephalosporin C | Descriptor: | 1,2-ETHANEDIOL, CEPHALOSPORIN ACYLASE, PHOSPHATE ION | Authors: | Fritz-Wolf, K, Koller, K.P, Lange, G, Liesum, A, Sauber, K, Schreuder, H, Aretz, W, Kabsch, W. | Deposit date: | 2001-08-07 | Release date: | 2002-01-01 | Last modified: | 2019-05-08 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structure-Based Prediction of Modifications in Glutarylamidase to Allow Single-Step Enzymatic Production of 7-Aminocephalosporanic Acid from Cephalosporin C. Protein Sci., 11, 2002
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1GKP
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![BU of 1gkp by Molmil](/molmil-images/mine/1gkp) | D-Hydantoinase (Dihydropyrimidinase) from Thermus sp. in space group C2221 | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, HYDANTOINASE, SULFATE ION, ... | Authors: | Abendroth, J, Niefind, K, Schomburg, D. | Deposit date: | 2001-08-20 | Release date: | 2002-06-27 | Last modified: | 2019-07-24 | Method: | X-RAY DIFFRACTION (1.295 Å) | Cite: | X-Ray Structure of a Dihydropyrimidinase from Thermus Sp. At 1.3 A Resolution J.Mol.Biol., 320, 2002
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7EPM
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![BU of 7epm by Molmil](/molmil-images/mine/7epm) | human LDHC complexed with NAD+ and ethylamino acetic acid | Descriptor: | 2-(ethylamino)-2-oxidanylidene-ethanoic acid, L-lactate dehydrogenase C chain, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... | Authors: | Yu, Y, Chen, Q. | Deposit date: | 2021-04-27 | Release date: | 2022-03-02 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Identification of human LDHC4 as a potential target for anticancer drug discovery. Acta Pharm Sin B, 12, 2022
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3OKF
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![BU of 3okf by Molmil](/molmil-images/mine/3okf) | 2.5 Angstrom Resolution Crystal Structure of 3-Dehydroquinate Synthase (aroB) from Vibrio cholerae | Descriptor: | 3-dehydroquinate synthase, CHLORIDE ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... | Authors: | Minasov, G, Light, S.H, Shuvalova, L, Papazisi, L, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2010-08-24 | Release date: | 2010-09-08 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | 2.5 Angstrom Resolution Crystal Structure of 3-Dehydroquinate Synthase (aroB) from Vibrio cholerae. TO BE PUBLISHED
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5K97
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![BU of 5k97 by Molmil](/molmil-images/mine/5k97) | Flap endonuclease 1 (FEN1) D233N with cleaved product fragment and Sm3+ | Descriptor: | 1,2-ETHANEDIOL, DNA (5'-D(*AP*CP*CP*GP*TP*CP*C)-3'), DNA (5'-D(*AP*CP*TP*CP*TP*GP*CP*CP*TP*CP*AP*AP*GP*AP*CP*GP*GP*T)-3'), ... | Authors: | Tsutakawa, S.E, Arvai, A.S, Tainer, J.A. | Deposit date: | 2016-05-31 | Release date: | 2017-06-28 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.102 Å) | Cite: | Phosphate steering by Flap Endonuclease 1 promotes 5'-flap specificity and incision to prevent genome instability. Nat Commun, 8, 2017
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1G7L
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![BU of 1g7l by Molmil](/molmil-images/mine/1g7l) | CRYSTAL STRUCTURE OF HEN EGG WHITE LYSOZYME (HEL) COMPLEXED WITH THE MUTANT ANTI-HEL MONOCLONAL ANTIBODY D1.3 (VLW92S) | Descriptor: | ANTI-HEN EGG WHITE LYSOZYME MONOCLONAL ANTIBODY D1.3, LYSOZYME C | Authors: | Sundberg, E.J, Urrutia, M, Braden, B.C, Isern, J, Mariuzza, R.A. | Deposit date: | 2000-11-10 | Release date: | 2000-11-22 | Last modified: | 2021-10-27 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Estimation of the hydrophobic effect in an antigen-antibody protein-protein interface. Biochemistry, 39, 2000
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4X4T
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![BU of 4x4t by Molmil](/molmil-images/mine/4x4t) | |
1SIR
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![BU of 1sir by Molmil](/molmil-images/mine/1sir) | The Crystal Structure and Mechanism of Human Glutaryl-CoA Dehydrogenase | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, Glutaryl-CoA dehydrogenase, S-4-NITROBUTYRYL-COA | Authors: | Wang, M, Fu, Z, Paschke, R, Goodman, S.L, Frerman, F.E, Kim, J.J. | Deposit date: | 2004-03-01 | Release date: | 2004-09-07 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Crystal Structures of Human Glutaryl-CoA Dehydrogenase with and without an Alternate Substrate: Structural Bases of Dehydrogenation and Decarboxylation Reactions Biochemistry, 43, 2004
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1GES
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![BU of 1ges by Molmil](/molmil-images/mine/1ges) | |
3OLT
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![BU of 3olt by Molmil](/molmil-images/mine/3olt) | |
1S5L
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![BU of 1s5l by Molmil](/molmil-images/mine/1s5l) | Architecture of the photosynthetic oxygen evolving center | Descriptor: | 2,3-DIMETHYL-5-(3,7,11,15,19,23,27,31,35-NONAMETHYL-2,6,10,14,18,22,26,30,34-HEXATRIACONTANONAENYL-2,5-CYCLOHEXADIENE-1,4-DIONE-2,3-DIMETHYL-5-SOLANESYL-1,4-BENZOQUINONE, BETA-CAROTENE, BICARBONATE ION, ... | Authors: | Ferreira, K.N, Iverson, T.M, Maghlaoui, K, Barber, J, Iwata, S. | Deposit date: | 2004-01-21 | Release date: | 2004-02-24 | Last modified: | 2021-03-03 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Architecture of the Photosynthetic Oxygen-Evolving Center Science, 303, 2004
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