1FXH
MUTANT OF PENICILLIN ACYLASE IMPAIRED IN CATALYSIS WITH PHENYLACETIC ACID IN THE ACTIVE SITE
Summary for 1FXH
Entry DOI | 10.2210/pdb1fxh/pdb |
Descriptor | PENICILLIN ACYLASE, CALCIUM ION, 2-PHENYLACETIC ACID, ... (5 entities in total) |
Functional Keywords | ntn-hydrolase fold, hydrolase |
Biological source | Escherichia coli More |
Cellular location | Periplasm: P06875 P06875 |
Total number of polymer chains | 2 |
Total formula weight | 86415.55 |
Authors | Alkema, W.B.,Hensgens, C.M.,Kroezinga, E.H.,de Vries, E.,Floris, R.,van der Laan, J.M.,Dijkstra, B.W.,Janssen, D.B. (deposition date: 2000-09-26, release date: 2001-03-28, Last modification date: 2024-02-07) |
Primary citation | Alkema, W.B.,Hensgens, C.M.,Kroezinga, E.H.,de Vries, E.,Floris, R.,van der Laan, J.M.,Dijkstra, B.W.,Janssen, D.B. Characterization of the beta-lactam binding site of penicillin acylase of Escherichia coli by structural and site-directed mutagenesis studies. Protein Eng., 13:857-863, 2000 Cited by PubMed: 11239085DOI: 10.1093/protein/13.12.857 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.97 Å) |
Structure validation
Download full validation report