1FXH

MUTANT OF PENICILLIN ACYLASE IMPAIRED IN CATALYSIS WITH PHENYLACETIC ACID IN THE ACTIVE SITE

Summary for 1FXH

• Entry DOI: 10.2210/pdb1fxh/pdb
• Descriptor: PENICILLIN ACYLASE, CALCIUM ION, 2-PHENYLACETIC ACID, ... (5 entities in total)
• Functional Keywords: ntn-hydrolase fold, hydrolase
• Biological source: Escherichia coli; More
• Cellular location: Periplasm: P06875 P06875
• Total number of polymer chains: 2
• Total formula weight: 86415.55

Authors

Alkema, W.B.,Hensgens, C.M.,Kroezinga, E.H.,de Vries, E.,Floris, R.,van der Laan, J.M.,Dijkstra, B.W.,Janssen, D.B. (deposition date: 2000-09-26, release date: 2001-03-28, Last modification date: 2024-02-07)

• Primary citation: Alkema, W.B.,Hensgens, C.M.,Kroezinga, E.H.,de Vries, E.,Floris, R.,van der Laan, J.M.,Dijkstra, B.W.,Janssen, D.B.; Characterization of the beta-lactam binding site of penicillin acylase of Escherichia coli by structural and site-directed mutagenesis studies.; Protein Eng., 13:857-863, 2000; PubMed: 11239085; DOI: 10.1093/protein/13.12.857

Experimental method

X-RAY DIFFRACTION (1.97 Å)