1FXH
MUTANT OF PENICILLIN ACYLASE IMPAIRED IN CATALYSIS WITH PHENYLACETIC ACID IN THE ACTIVE SITE
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | PENICILLIN ACYLASE | polymer | 209 | 23838.8 | 1 | UniProt (P06875) In PDB | Escherichia coli | |
| 2 | B | PENICILLIN ACYLASE | polymer | 557 | 62400.5 | 1 | UniProt (P06875) Pfam (PF01804) In PDB | Escherichia coli | |
| 3 | B | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
| 4 | B | 2-PHENYLACETIC ACID | non-polymer | 136.1 | 1 | Chemie (PAC) | |||
| 5 | water | water | 18.0 | 653 | Chemie (HOH) |
Sequence modifications
B: 1 - 557 (UniProt: P06875)
| PDB | External Database | Details |
|---|---|---|
| Leu 148 | Val 437 | engineered mutation |
| Ala 241 | Asn 530 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 86239.3 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 176.2 | |
| All* | Total formula weight | 86415.5 |
