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4HGA
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BU of 4hga by Molmil
Structure of the variant histone H3.3-H4 heterodimer in complex with its chaperone DAXX
Descriptor: Death domain-associated protein 6, Histone H3.3, Histone H4, ...
Authors:Liu, C.P, Xiong, C.Y, Wang, M.Z, Yu, Z.L, Yang, N, Chen, P, Zhang, Z.G, Li, G.H, Xu, R.M.
Deposit date:2012-10-07
Release date:2012-11-07
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.799 Å)
Cite:Structure of the variant histone H3.3-H4 heterodimer in complex with its chaperone DAXX.
Nat.Struct.Mol.Biol., 19, 2012
4H9N
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BU of 4h9n by Molmil
Complex structure 1 of DAXX/H3.3(sub5)/H4
Descriptor: Death domain-associated protein 6, Histone H3.3, Histone H4, ...
Authors:Elsasser, S.J, Huang, H, Lewis, P.W, Chin, J.W, Allis, D.C, Patel, D.J.
Deposit date:2012-09-24
Release date:2012-10-10
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:DAXX chaperone envelops an H3.3/H4 dimer dictating H3.3-specific read out
To be Published
4J8V
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BU of 4j8v by Molmil
X-ray structure of NCP145 with bound chlorido(eta-6-p-cymene)(N-phenyl-2-pyridinecarbothioamide)ruthenium(II)
Descriptor: DNA (145-MER), Histone H2A, Histone H2B 1.1, ...
Authors:Adhireksan, Z, Davey, C.A.
Deposit date:2013-02-15
Release date:2013-05-08
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.58 Å)
Cite:Novel metal(II) arene 2-pyridinecarbothioamides: a rationale to orally active organometallic anticancer agents
CHEM SCI, 4, 2013
4KHA
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BU of 4kha by Molmil
Structural basis of histone H2A-H2B recognition by the essential chaperone FACT
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, Histone H2A, ...
Authors:Hondele, M, Halbach, F, Hassler, M, Ladurner, A.G.
Deposit date:2013-04-30
Release date:2013-05-29
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structural basis of histone H2A-H2B recognition by the essential chaperone FACT.
Nature, 499, 2013
4KGC
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BU of 4kgc by Molmil
Nucleosome Core Particle Containing (ETA6-P-CYMENE)-(1, 2-ETHYLENEDIAMINE)-RUTHENIUM
Descriptor: (ethane-1,2-diamine-kappa~2~N,N')[(1,2,3,4,5,6-eta)-1-methyl-4-(propan-2-yl)cyclohexane-1,2,3,4,5,6-hexayl]ruthenium, DNA (145-mer), Histone H2A, ...
Authors:Adhireksan, Z, Davey, C.A.
Deposit date:2013-04-29
Release date:2014-03-26
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.69 Å)
Cite:Ligand substitutions between ruthenium-cymene compounds can control protein versus DNA targeting and anticancer activity
Nat Commun, 5, 2014
4KUD
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BU of 4kud by Molmil
Crystal structure of N-terminal acetylated Sir3 BAH domain D205N mutant in complex with yeast nucleosome core particle
Descriptor: Histone H2A.2, Histone H2B.1, Histone H3, ...
Authors:Yang, D, Fang, Q, Wang, M, Ren, R, Wang, H, He, M, Sun, Y, Yang, N, Xu, R.M.
Deposit date:2013-05-22
Release date:2013-08-07
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (3.203 Å)
Cite:N alpha-acetylated Sir3 stabilizes the conformation of a nucleosome-binding loop in the BAH domain.
Nat.Struct.Mol.Biol., 20, 2013
6WZ5
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BU of 6wz5 by Molmil
Bridging of double-strand DNA break activates PARP2/HPF1 to modify chromatin
Descriptor: DNA (153-MER), Histone H2A, Histone H2B 1.1, ...
Authors:Halic, M, Bilokapic, S.
Deposit date:2020-05-13
Release date:2020-09-16
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (2.2 Å)
Cite:Bridging of DNA breaks activates PARP2-HPF1 to modify chromatin.
Nature, 585, 2020
6X0N
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BU of 6x0n by Molmil
Bridging of double-strand DNA break activates PARP2/HPF1 to modify chromatin
Descriptor: DNA (167-MER), Histone H2A, Histone H2B 1.1, ...
Authors:Halic, M, Bilokapic, S.
Deposit date:2020-05-16
Release date:2020-09-16
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (10 Å)
Cite:Bridging of DNA breaks activates PARP2-HPF1 to modify chromatin.
Nature, 585, 2020
6X59
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BU of 6x59 by Molmil
The mouse cGAS catalytic domain binding to human assembled nucleosome
Descriptor: Cyclic GMP-AMP synthase, DNA, Histone H2A type 1, ...
Authors:Pengbiao, X, Pingwei, L, Baoyu, Z.
Deposit date:2020-05-25
Release date:2020-09-16
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (2.98 Å)
Cite:The molecular basis of tight nuclear tethering and inactivation of cGAS.
Nature, 587, 2020
3W99
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BU of 3w99 by Molmil
Crystal Structure of Human Nucleosome Core Particle lacking H4 N-terminal region
Descriptor: 146-mer DNA, Histone H2A type 1-B/E, Histone H2B type 1-J, ...
Authors:Iwasaki, W, Miya, Y, Horikoshi, N, Osakabe, A, Tachiwana, H, Shibata, T, Kagawa, W, Kurumizaka, H.
Deposit date:2013-04-01
Release date:2013-08-28
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (3 Å)
Cite:Contribution of histone N-terminal tails to the structure and stability of nucleosomes
FEBS Open Bio, 3, 2013
3W98
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BU of 3w98 by Molmil
Crystal Structure of Human Nucleosome Core Particle lacking H3.1 N-terminal region
Descriptor: 146-mer DNA, Histone H2A type 1-B/E, Histone H2B type 1-J, ...
Authors:Iwasaki, W, Miya, Y, Horikoshi, N, Osakabe, A, Tachiwana, H, Shibata, T, Kagawa, W, Kurumizaka, H.
Deposit date:2013-04-01
Release date:2013-08-28
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (3.42 Å)
Cite:Contribution of histone N-terminal tails to the structure and stability of nucleosomes
FEBS Open Bio, 3, 2013
3W97
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BU of 3w97 by Molmil
Crystal Structure of Human Nucleosome Core Particle lacking H2B N-terminal region
Descriptor: 146-mer DNA, Histone H2A type 1-B/E, Histone H2B type 1-J, ...
Authors:Iwasaki, W, Miya, Y, Horikoshi, N, Osakabe, A, Tachiwana, H, Shibata, T, Kagawa, W, Kurumizaka, H.
Deposit date:2013-04-01
Release date:2013-08-28
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Contribution of histone N-terminal tails to the structure and stability of nucleosomes
FEBS Open Bio, 3, 2013
6XWT
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BU of 6xwt by Molmil
drosophila melanogaster CENP-A/H4 bound to N-terminal CAL1 fragment
Descriptor: Chromosome alignment defect 1, Histone H3-like centromeric protein cid, Histone H4
Authors:Jeyaprakash, A.A, Medina-Pritchard, B, Lazou, V, Zou, J, Byron, O, Abad, M.A, Rappsilber, J, Heun, P.
Deposit date:2020-01-24
Release date:2020-04-01
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3.47 Å)
Cite:Structural basis for centromere maintenance by Drosophila CENP-A chaperone CAL1.
Embo J., 39, 2020
3WA9
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BU of 3wa9 by Molmil
The nucleosome containing human H2A.Z.1
Descriptor: DNA (146-MER), Histone H2A.Z, Histone H2B type 1-J, ...
Authors:Horikoshi, N, Sato, K, Shimada, K, Arimura, Y, Osakabe, A, Tachiwana, H, Iwasaki, W, Kagawa, W, Harata, M, Kimura, H, Kurumizaka, H.
Deposit date:2013-04-30
Release date:2013-12-18
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (3.07 Å)
Cite:Structural polymorphism in the L1 loop regions of human H2A.Z.1 and H2A.Z.2
Acta Crystallogr.,Sect.D, 69, 2013
3W96
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BU of 3w96 by Molmil
Crystal Structure of Human Nucleosome Core Particle lacking H2A N-terminal region
Descriptor: 146-mer DNA, CHLORIDE ION, Histone H2A type 1-B/E, ...
Authors:Iwasaki, W, Miya, Y, Horikoshi, N, Osakabe, A, Tachiwana, H, Shibata, T, Kagawa, W, Kurumizaka, H.
Deposit date:2013-04-01
Release date:2013-08-28
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (3 Å)
Cite:Contribution of histone N-terminal tails to the structure and stability of nucleosomes
FEBS Open Bio, 3, 2013
3WAA
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BU of 3waa by Molmil
The nucleosome containing human H2A.Z.2
Descriptor: DNA (146-MER), Histone H2A.V, Histone H2B type 1-J, ...
Authors:Horikoshi, N, Sato, K, Shimada, K, Arimura, Y, Osakabe, A, Tachiwana, H, Iwasaki, W, Kagawa, W, Harata, M, Kimura, H, Kurumizaka, H.
Deposit date:2013-04-30
Release date:2013-12-18
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural polymorphism in the L1 loop regions of human H2A.Z.1 and H2A.Z.2
Acta Crystallogr.,Sect.D, 69, 2013
6Y36
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BU of 6y36 by Molmil
CCAAT-binding complex from Aspergillus fumigatus with cccA DNA
Descriptor: CCAAT-binding factor complex subunit HapC, CCAAT-binding factor complex subunit HapE, CCAAT-binding transcription factor subunit HAPB, ...
Authors:Groll, M, Huber, E.M.
Deposit date:2020-02-17
Release date:2020-05-27
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis of HapE P88L -linked antifungal triazole resistance in Aspergillus fumigatus .
Life Sci Alliance, 3, 2020
6Y5E
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BU of 6y5e by Molmil
Structure of human cGAS (K394E) bound to the nucleosome (focused refinement of cGAS-NCP subcomplex)
Descriptor: Cyclic GMP-AMP synthase, DNA (153-MER), Histone H2A type 2-C, ...
Authors:Pathare, G.R, Cavadini, S, Kempf, G, Thoma, N.H.
Deposit date:2020-02-25
Release date:2020-09-23
Last modified:2020-12-09
Method:ELECTRON MICROSCOPY (3.15 Å)
Cite:Structural mechanism of cGAS inhibition by the nucleosome.
Nature, 587, 2020
3X1U
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BU of 3x1u by Molmil
Crystal structure of nucleosome core particle in the presence of histone variants involved in reprogramming
Descriptor: CHLORIDE ION, DNA (146-MER), Histone H2A, ...
Authors:Sivaraman, P, Kumarevel, T.S.
Deposit date:2014-11-28
Release date:2015-09-23
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (3.25 Å)
Cite:Structural and functional analyses of nucleosome complexes with mouse histone variants TH2a and TH2b, involved in reprogramming.
Biochem.Biophys.Res.Commun., 464, 2015
3X1V
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BU of 3x1v by Molmil
Crystal structure of nucleosome core particle in the presence of histone variant involved in reprogramming
Descriptor: CHLORIDE ION, DNA (146-MER), Histone H2A type 1-B/E, ...
Authors:Sivaraman, P, Kumarevel, T.S.
Deposit date:2014-11-28
Release date:2015-09-23
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.921 Å)
Cite:Structural and functional analyses of nucleosome complexes with mouse histone variants TH2a and TH2b, involved in reprogramming
Biochem.Biophys.Res.Commun., 464, 2015
3X1T
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BU of 3x1t by Molmil
Crystal structure of nucleosome core particle consisting of mouse testis specific histone variants H2aa and H2ba
Descriptor: CHLORIDE ION, DNA (146-MER), Histone H2A, ...
Authors:Sivaraman, P, Kumarevel, T.S.
Deposit date:2014-11-27
Release date:2015-09-23
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.808 Å)
Cite:Structural and functional analyses of nucleosome complexes with mouse histone variants TH2a and TH2b, involved in reprogramming
Biochem.Biophys.Res.Commun., 464, 2015
6ESG
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BU of 6esg by Molmil
Nucleosome breathing : Class 2
Descriptor: DNA (141-MER), Histone H2A, Histone H2B 1.1, ...
Authors:Bilokapic, S, Halic, M.
Deposit date:2017-10-20
Release date:2017-12-20
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (5.4 Å)
Cite:Histone octamer rearranges to adapt to DNA unwrapping.
Nat. Struct. Mol. Biol., 25, 2018
3X1S
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BU of 3x1s by Molmil
Crystal structure of the nucleosome core particle
Descriptor: CHLORIDE ION, DNA (146-MER), Histone H2A type 1-B/E, ...
Authors:Sivaraman, P, Kumarevel, T.S.
Deposit date:2014-11-27
Release date:2015-09-23
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.805 Å)
Cite:Structural and functional analyses of nucleosome complexes with mouse histone variants TH2a and TH2b, involved in reprogramming
Biochem.Biophys.Res.Commun., 464, 2015
6XJD
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BU of 6xjd by Molmil
Two mouse cGAS catalytic domain binding to human assembled nucleosome
Descriptor: Cyclic GMP-AMP synthase, DNA (145-MER), Histone H2A type 1, ...
Authors:Xu, P, Li, P, Zhao, B.
Deposit date:2020-06-23
Release date:2020-09-16
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (6.8 Å)
Cite:The molecular basis of tight nuclear tethering and inactivation of cGAS.
Nature, 587, 2020
6ESH
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BU of 6esh by Molmil
Nucleosome breathing : Class 3
Descriptor: DNA (137-MER), Histone H2A, Histone H2B 1.1, ...
Authors:Bilokapic, S, Halic, M.
Deposit date:2017-10-20
Release date:2017-12-20
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (5.1 Å)
Cite:Histone octamer rearranges to adapt to DNA unwrapping.
Nat. Struct. Mol. Biol., 25, 2018

222036

數據於2024-07-03公開中

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