6T29
 
 | | Crystal structure of human calmodulin-dependent protein kinase 1D (CAMK1D) bound to compound 18 (CS587) | | Descriptor: | 1,2-ETHANEDIOL, 2-[(3~{S})-3-azanylpiperidin-1-yl]-4-[[3,5-bis(2-cyanopropan-2-yl)phenyl]amino]pyrimidine-5-carboxamide, Calcium/calmodulin-dependent protein kinase type 1D, ... | | Authors: | Kraemer, A, Sorrell, F, Butterworth, S, Edwards, A.M, Arrowsmith, C.H, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) | | Deposit date: | 2019-10-08 | | Release date: | 2019-11-13 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (1.484 Å) | | Cite: | Discovery of Highly Selective Inhibitors of Calmodulin-Dependent Kinases That Restore Insulin Sensitivity in the Diet-Induced Obesityin VivoMouse Model.
J.Med.Chem., 63, 2020
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6MUD
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6MUE
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2RO8
 | | Solution structure of calcium bound soybean calmodulin isoform 1 N-terminal domain | | Descriptor: | CALCIUM ION, Calmodulin | | Authors: | Ishida, H, Huang, H, Yamniuk, A.P, Takaya, Y, Vogel, H.J. | | Deposit date: | 2008-03-14 | | Release date: | 2008-04-08 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | The solution structures of two soybean calmodulin isoforms provide a structural basis for their selective target activation properties
J.Biol.Chem., 283, 2008
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6PJX
 | | Crystal Structure of G Protein-Coupled Receptor Kinase 5 (GRK5) in Complex with Calmodulin (CaM) | | Descriptor: | CALCIUM ION, Calmodulin, G protein-coupled receptor kinase 5, ... | | Authors: | Bhardwaj, A, Komolov, K.E, Sulon, S, Benovic, J.L. | | Deposit date: | 2019-06-28 | | Release date: | 2020-12-09 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (1.96 Å) | | Cite: | Structure of a GRK5-Calmodulin Complex Reveals Molecular Mechanism of GRK Activation and Substrate Targeting.
Mol.Cell, 81, 2021
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7L8V
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1DEG
 | | THE LINKER OF DES-GLU84 CALMODULIN IS BENT AS SEEN IN THE CRYSTAL STRUCTURE | | Descriptor: | CALCIUM ION, CALMODULIN | | Authors: | Raghunathan, S, Chandross, R, Cheng, B.P, Persechini, A, Sobottk, S.E, Kretsinger, R.H. | | Deposit date: | 1993-06-07 | | Release date: | 1994-05-31 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | The linker of des-Glu84-calmodulin is bent.
Proc.Natl.Acad.Sci.Usa, 90, 1993
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1MUX
 | | SOLUTION NMR STRUCTURE OF CALMODULIN/W-7 COMPLEX: THE BASIS OF DIVERSITY IN MOLECULAR RECOGNITION, 30 STRUCTURES | | Descriptor: | CALCIUM ION, CALMODULIN, N-(6-AMINOHEXYL)-5-CHLORO-1-NAPHTHALENESULFONAMIDE | | Authors: | Osawa, M, Swindells, M.B, Tanikawa, J, Tanaka, T, Mase, T, Furuya, T, Ikura, M. | | Deposit date: | 1997-09-06 | | Release date: | 1998-10-14 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Solution structure of calmodulin-W-7 complex: the basis of diversity in molecular recognition.
J.Mol.Biol., 276, 1998
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3CLN
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1NIW
 | | Crystal structure of endothelial nitric oxide synthase peptide bound to calmodulin | | Descriptor: | 1,2-ETHANEDIOL, CALCIUM ION, Nitric-oxide synthase, ... | | Authors: | Aoyagi, M, Arvai, A.S, Tainer, J.A, Getzoff, E.D. | | Deposit date: | 2002-12-26 | | Release date: | 2003-02-18 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.05 Å) | | Cite: | Structural basis for endothelial nitric oxide synthase binding to calmodulin
Embo J., 22, 2003
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2BBM
 | | SOLUTION STRUCTURE OF A CALMODULIN-TARGET PEPTIDE COMPLEX BY MULTIDIMENSIONAL NMR | | Descriptor: | CALCIUM ION, CALMODULIN, MYOSIN LIGHT CHAIN KINASE | | Authors: | Clore, G.M, Bax, A, Ikura, M, Gronenborn, A.M. | | Deposit date: | 1992-07-16 | | Release date: | 1994-01-31 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Solution structure of a calmodulin-target peptide complex by multidimensional NMR.
Science, 256, 1992
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2BBN
 | | SOLUTION STRUCTURE OF A CALMODULIN-TARGET PEPTIDE COMPLEX BY MULTIDIMENSIONAL NMR | | Descriptor: | CALCIUM ION, CALMODULIN, MYOSIN LIGHT CHAIN KINASE | | Authors: | Clore, G.M, Bax, A, Ikura, M, Gronenborn, A.M. | | Deposit date: | 1992-07-16 | | Release date: | 1994-01-31 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Solution structure of a calmodulin-target peptide complex by multidimensional NMR.
Science, 256, 1992
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1CDL
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1CTR
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3IF7
 | | Structure of Calmodulin complexed with its first endogenous inhibitor, sphingosylphosphorylcholine | | Descriptor: | 2-{[(R)-{[(2S,3R,4E)-2-amino-3-hydroxyoctadec-4-en-1-yl]oxy}(hydroxy)phosphoryl]oxy}-N,N,N-trimethylethanaminium, CALCIUM ION, Calmodulin | | Authors: | Kovacs, E, Harmat, V, Toth, J, Vertessy, B.G, Modos, K, Kardos, J, Liliom, K. | | Deposit date: | 2009-07-24 | | Release date: | 2010-06-30 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Structure and mechanism of calmodulin binding to a signaling sphingolipid reveal new aspects of lipid-protein interactions
Faseb J., 24, 2010
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5TP6
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3G43
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2LV6
 | | The complex between Ca-Calmodulin and skeletal muscle myosin light chain kinase from combination of NMR and aqueous and contrast-matched SAXS data | | Descriptor: | CALCIUM ION, Calmodulin, Myosin light chain kinase 2, ... | | Authors: | Grishaev, A.V, Anthis, N.J, Clore, G.M. | | Deposit date: | 2012-06-29 | | Release date: | 2013-02-20 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR, SOLUTION SCATTERING | | Cite: | Contrast-matched small-angle X-ray scattering from a heavy-atom-labeled protein in structure determination: application to a lead-substituted calmodulin-peptide complex.
J.Am.Chem.Soc., 134, 2012
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2L7L
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3EWV
 | | Crystal Structure of calmodulin complexed with a peptide | | Descriptor: | CALCIUM ION, Calmodulin, Tumor necrosis factor receptor superfamily member 16 | | Authors: | Jiang, T, Cao, P, Gong, Y, Yu, H.J, Gui, W.J, Zhang, W.T. | | Deposit date: | 2008-10-16 | | Release date: | 2009-10-20 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Structural insights into the mechanism of calmodulin binding to death receptors.
Acta Crystallogr.,Sect.D, 70, 2014
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2N27
 | | Competitive inhibition of TRPV1 calmodulin interaction by vanilloids | | Descriptor: | (6E)-N-(4-hydroxy-3-methoxybenzyl)-8-methylnon-6-enamide, CALCIUM ION, Calmodulin | | Authors: | Hetenyi, A, Nemeth, L, Weber, E, Szakonyi, G, Winter, Z, Josvay, K, Bartus, E, Olah, Z, Martinek, T.A. | | Deposit date: | 2015-04-29 | | Release date: | 2016-07-06 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Competitive inhibition of TRPV1-calmodulin interaction by vanilloids.
Febs Lett., 590, 2016
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2KN2
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2LQC
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2KDU
 | | Structural basis of the Munc13-1/Ca2+-Calmodulin interaction: A novel 1-26 calmodulin binding motif with a bipartite binding mode | | Descriptor: | CALCIUM ION, Calmodulin, Protein unc-13 homolog A | | Authors: | Rodriguez-Castaneda, F.A, Maestre-Martinez, M, Coudevylle, N, Dimova, K, Jahn, O, Junge, H, Becker, S, Brose, N, Carlomagno, T, Griesinger, C. | | Deposit date: | 2009-01-19 | | Release date: | 2009-12-15 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Modular architecture of Munc13/calmodulin complexes: dual regulation by Ca2+ and possible function in short-term synaptic plasticity.
Embo J., 29, 2010
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2LGF
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