Structure of Calmodulin complexed with its first endogenous inhibitor, sphingosylphosphorylcholine

Summary for 3IF7

DescriptorCalmodulin, CALCIUM ION, 2-{[(R)-{[(2S,3R,4E)-2-amino-3-hydroxyoctadec-4-en-1-yl]oxy}(hydroxy)phosphoryl]oxy}-N,N,N-trimethylethanaminium, ... (4 entities in total)
Functional Keywordsef-hand, phospholipid, calcium binding protein, isopeptide bond, methylation, phosphoprotein
Biological sourceBos taurus (Bovine)
Cellular locationCytoplasm P62157
Total number of polymer chains1
Total molecular weight18744.17
Kovacs, E.,Harmat, V.,Toth, J.,Vertessy, B.G.,Modos, K.,Kardos, J.,Liliom, K. (deposition date: 2009-07-24, release date: 2010-06-30, Last modification date: 2011-07-13)
Primary citation
Kovacs, E.,Harmat, V.,Toth, J.,Vertessy, B.G.,Modos, K.,Kardos, J.,Liliom, K.
Structure and mechanism of calmodulin binding to a signaling sphingolipid reveal new aspects of lipid-protein interactions
Faseb J., 24:3829-3839, 2010
PubMed: 20522785 (PDB entries with the same primary citation)
DOI: 10.1096/fj.10-155614
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.244170 0.9% 2.8%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
PDB entries from 2020-10-14