7L8V
NMR Structure of half-calcified calmodulin mutant (CaMEF12) bound to the IQ-motif of CaV1.2
Summary for 7L8V
Entry DOI | 10.2210/pdb7l8v/pdb |
NMR Information | BMRB: 27692 |
Descriptor | Calmodulin-1, Voltage-dependent L-type calcium channel subunit alpha-1C, CALCIUM ION (3 entities in total) |
Functional Keywords | cav1.2, l-type channel, ef-hand, metal binding protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 19344.85 |
Authors | Ames, J.B. (deposition date: 2021-01-01, release date: 2022-07-06, Last modification date: 2024-05-15) |
Primary citation | Bartels, P.,Salveson, I.,Coleman, A.M.,Anderson, D.E.,Jeng, G.,Estrada-Tobar, Z.M.,Man, K.N.M.,Yu, Q.,Kuzmenkina, E.,Nieves-Cintron, M.,Navedo, M.F.,Horne, M.C.,Hell, J.W.,Ames, J.B. Half-calcified calmodulin promotes basal activity and inactivation of the L-type calcium channel Ca V 1.2. J.Biol.Chem., 298:102701-102701, 2022 Cited by PubMed: 36395884DOI: 10.1016/j.jbc.2022.102701 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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