Loading
PDBj
MenuPDBj@FacebookPDBj@X(formerly Twitter)PDBj@BlueSkyPDBj@YouTubewwPDB FoundationwwPDBDonate
RCSB PDBPDBeBMRBAdv. SearchSearch help

5KS7
DownloadVisualize
BU of 5ks7 by Molmil
Crystal structure of Listeria monocytogenes OpuCA CBS domain dimer in complex with cyclic-di-AMP
Descriptor: (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide, Carnitine transport ATP-binding protein OpuCA
Authors:Choi, P.H, Tong, L.
Deposit date:2016-07-07
Release date:2016-07-20
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Cyclic di-AMP targets the cystathionine beta-synthase domain of the osmolyte transporter OpuC.
Mol.Microbiol., 102, 2016
8IDW
DownloadVisualize
BU of 8idw by Molmil
Crystal structure of Fic protein from Mycoplasma mycoides in complex with AMPPNP
Descriptor: AMP PHOSPHORAMIDATE, Cell filamentation protein Fic, GLYCEROL, ...
Authors:Zhang, H, Zhao, H.F.
Deposit date:2023-02-14
Release date:2024-08-14
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.304 Å)
Cite:Crystal structure of Fic protein from Mycoplasma mycoides in complex with AMPPNP
To Be Published
7PZA
DownloadVisualize
BU of 7pza by Molmil
Structure of the Clr-cAMP-DNA complex
Descriptor: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, DNA (5'-D(*CP*TP*AP*GP*GP*TP*AP*AP*CP*AP*TP*TP*AP*CP*TP*CP*GP)-3'), DNA (5'-D(*GP*CP*GP*AP*GP*TP*AP*AP*TP*GP*TP*TP*AP*C)-3'), ...
Authors:Werel, L, Essen, L.-O.
Deposit date:2021-10-11
Release date:2022-11-02
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.72 Å)
Cite:Structural Basis of Dual Specificity of Sinorhizobium meliloti Clr, a cAMP and cGMP Receptor Protein.
Mbio, 14, 2023
3IED
DownloadVisualize
BU of 3ied by Molmil
Crystal structure of N-terminal domain of Plasmodium falciparum Hsp90 (PF14_0417) in complex with AMPPN
Descriptor: AMP PHOSPHORAMIDATE, Heat shock protein
Authors:Pizarro, J.C, Wernimont, A.K, Lew, J, Hutchinson, A, Artz, J.D, Amaya, M.F, Plotnikova, O, Vedadi, M, Kozieradzki, I, Weigelt, J, Edwards, A.M, Arrowsmith, C.H, Bountra, C, Botchkarev, A, Hui, R, Hills, T, Structural Genomics Consortium (SGC)
Deposit date:2009-07-22
Release date:2009-08-25
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Crystal structure of N-terminal domain of Plasmodium falciparum Hsp90 (PF14_0417) in complex with AMPPN
TO BE PUBLISHED
8VUX
DownloadVisualize
BU of 8vux by Molmil
Cryo-EM structure of human ABC transporter (hABCC1) bound to cGAMP
Descriptor: CHOLESTEROL HEMISUCCINATE, Multidrug resistance-associated protein 1, cGAMP
Authors:Shinde, O, Li, P.
Deposit date:2024-01-30
Release date:2024-12-25
Last modified:2025-01-29
Method:ELECTRON MICROSCOPY (3.54 Å)
Cite:Structures of ATP-binding cassette transporter ABCC1 reveal the molecular basis of cyclic dinucleotide cGAMP export.
Immunity, 58, 2025
1T8S
DownloadVisualize
BU of 1t8s by Molmil
Crystal Structure of E.coli AMP Nucleosidase complexed with formicin 5'-monophosphate
Descriptor: AMP nucleosidase, FORMYCIN-5'-MONOPHOSPHATE
Authors:Zhang, Y, Cottet, S.E, Ealick, S.E.
Deposit date:2004-05-13
Release date:2004-08-17
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure of Escherichia coli AMP Nucleosidase Reveals Similarity to Nucleoside Phosphorylases
STRUCTURE, 12, 2004
1T8W
DownloadVisualize
BU of 1t8w by Molmil
Crystal Structure of E. coli AMP Nucleosidase
Descriptor: AMP nucleosidase
Authors:Zhang, Y, Cottet, S.E, Ealick, S.E.
Deposit date:2004-05-13
Release date:2004-08-17
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of Escherichia coli AMP Nucleosidase Reveals Similarity to Nucleoside Phosphorylases
STRUCTURE, 12, 2004
1T8R
DownloadVisualize
BU of 1t8r by Molmil
Crystal Structure of E. coli AMP Nucleosidase
Descriptor: AMP nucleosidase
Authors:Zhang, Y, Cottet, S.E, Ealick, S.E.
Deposit date:2004-05-13
Release date:2004-08-17
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure of Escherichia coli AMP Nucleosidase Reveals Similarity to Nucleoside Phosphorylases
STRUCTURE, 12, 2004
1T8Y
DownloadVisualize
BU of 1t8y by Molmil
Crystal Structure of E.coli AMP Nucleosidase complexed with phosphate
Descriptor: AMP nucleosidase, PHOSPHATE ION
Authors:Zhang, Y, Cottet, S.E, Ealick, S.E.
Deposit date:2004-05-13
Release date:2004-08-17
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure of Escherichia coli AMP Nucleosidase Reveals Similarity to Nucleoside Phosphorylases
STRUCTURE, 12, 2004
8T00
DownloadVisualize
BU of 8t00 by Molmil
Reconstituted E. coli RNA polymerase post-termination complex on negatively-supercoiled DNA: closed duplex DNA (rPTCc)
Descriptor: DNA (26-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Brewer, J.J, Darst, S.A, Campbell, E.A.
Deposit date:2023-05-31
Release date:2025-04-02
Last modified:2025-06-04
Method:ELECTRON MICROSCOPY (4.69 Å)
Cite:RapA opens the RNA polymerase clamp to disrupt post-termination complexes and prevent cytotoxic R-loop formation.
Nat.Struct.Mol.Biol., 32, 2025
8T0L
DownloadVisualize
BU of 8t0l by Molmil
E. coli Sw2/Snf2 ATPase RapA bound to both ADP-AlF3 and reconstituted E. coli RNA polymerase post-termination complex on negatively-supercoiled DNA
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, DNA (29-MER), ...
Authors:Brewer, J.J, Darst, S.A, Campbell, E.A.
Deposit date:2023-06-01
Release date:2025-04-02
Last modified:2025-04-30
Method:ELECTRON MICROSCOPY (3.62 Å)
Cite:RapA opens the RNA polymerase clamp to disrupt post-termination complexes and prevent cytotoxic R-loop formation.
Nat.Struct.Mol.Biol., 32, 2025
8T02
DownloadVisualize
BU of 8t02 by Molmil
Reconstituted E. coli RNA polymerase post-termination complex on negatively-supercoiled DNA: unwinding duplex DNA (rPTCi)
Descriptor: DNA (25-MER), DNA (26-MER), DNA-directed RNA polymerase subunit alpha, ...
Authors:Brewer, J.J, Darst, S.A, Campbell, E.A.
Deposit date:2023-05-31
Release date:2025-04-02
Last modified:2025-05-28
Method:ELECTRON MICROSCOPY (3.79 Å)
Cite:RapA opens the RNA polymerase clamp to disrupt post-termination complexes and prevent cytotoxic R-loop formation.
Nat.Struct.Mol.Biol., 32, 2025
1STC
DownloadVisualize
BU of 1stc by Molmil
CAMP-DEPENDENT PROTEIN KINASE, ALPHA-CATALYTIC SUBUNIT IN COMPLEX WITH STAUROSPORINE
Descriptor: CAMP-DEPENDENT PROTEIN KINASE, PROTEIN KINASE INHIBITOR, STAUROSPORINE
Authors:Prade, L, Engh, R.A, Girod, A, Kinzel, V, Huber, R, Bossemeyer, D.
Deposit date:1997-10-10
Release date:1998-02-25
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Staurosporine-induced conformational changes of cAMP-dependent protein kinase catalytic subunit explain inhibitory potential.
Structure, 5, 1997
5O4P
DownloadVisualize
BU of 5o4p by Molmil
Crystal structure of AMPylated GRP78
Descriptor: 78 kDa glucose-regulated protein, ADENOSINE MONOPHOSPHATE, SULFATE ION
Authors:Yan, Y, Chen, R, Ron, D, Read, R.
Deposit date:2017-05-30
Release date:2017-11-01
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:AMPylation targets the rate-limiting step of BiP's ATPase cycle for its functional inactivation.
Elife, 6, 2017
8SI0
DownloadVisualize
BU of 8si0 by Molmil
Structure of binary complex of human cGAS and bound cGAMP
Descriptor: Cyclic GMP-AMP synthase, ZINC ION, cGAMP
Authors:Wu, S, Sohn, J.
Deposit date:2023-04-14
Release date:2024-04-24
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:The structural basis for 2'-5'/3'-5'-cGAMP synthesis by cGAS.
Nat Commun, 15, 2024
1TXR
DownloadVisualize
BU of 1txr by Molmil
X-ray crystal structure of bestatin bound to AAP
Descriptor: 2-(3-AMINO-2-HYDROXY-4-PHENYL-BUTYRYLAMINO)-4-METHYL-PENTANOIC ACID, Bacterial leucyl aminopeptidase, ZINC ION
Authors:Stamper, C.C, Holz, R.C, Ringe, D, Petsko, G.A.
Deposit date:2004-07-06
Release date:2004-07-20
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:Spectroscopic and X-ray Crystallographic Characterization of Bestatin Bound to the Aminopeptidase from Aeromonas (Vibrio) proteolytica.
Biochemistry, 43, 2004
8SZW
DownloadVisualize
BU of 8szw by Molmil
Reconstituted E. coli RNA polymerase post-termination complex on negatively-supercoiled DNA: open duplex DNA (rPTCo)
Descriptor: DNA (25-MER), DNA (27-MER), DNA-directed RNA polymerase subunit alpha, ...
Authors:Brewer, J.J, Darst, S.A, Campbell, E.A.
Deposit date:2023-05-30
Release date:2025-04-02
Last modified:2025-04-30
Method:ELECTRON MICROSCOPY (3.63 Å)
Cite:RapA opens the RNA polymerase clamp to disrupt post-termination complexes and prevent cytotoxic R-loop formation.
Nat.Struct.Mol.Biol., 32, 2025
2I9D
DownloadVisualize
BU of 2i9d by Molmil
chloramphenicol acetyltransferase
Descriptor: Chloramphenicol acetyltransferase
Authors:Duke, N.E.C, Li, H, Abdullah, J, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
Deposit date:2006-09-05
Release date:2006-10-17
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:chloramphenicol acetyltransferase
To be Published
2VHE
DownloadVisualize
BU of 2vhe by Molmil
PglD-CoA complex: An acetyl transferase from Campylobacter jejuni
Descriptor: ACETYLTRANSFERASE, COENZYME A, SULFATE ION
Authors:Rangarajan, E.S, Ruane, K.M, Sulea, T, Watson, D.C, Proteau, A, Leclerc, S, Cygler, M, Matte, A, Young, N.M.
Deposit date:2007-11-21
Release date:2008-01-29
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure and Active Site Residues of Pgld, an N-Acetyltransferase from the Bacillosamine Synthetic Pathway Required for N-Glycan Synthesis in Campylobacter Jejuni
Biochemistry, 47, 2008
6F9V
DownloadVisualize
BU of 6f9v by Molmil
Crystal structure of human Angiotensin-1 converting enzyme N-domain in complex with Sampatrilat.
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Cozier, G.E, Acharya, K.R.
Deposit date:2017-12-15
Release date:2018-03-07
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (1.69 Å)
Cite:Crystal structures of sampatrilat and sampatrilat-Asp in complex with human ACE - a molecular basis for domain selectivity.
FEBS J., 285, 2018
7MWZ
DownloadVisualize
BU of 7mwz by Molmil
Structure of drosophila STING in complex with 3'2'-cGAMP
Descriptor: 3'2'-cGAMP, STING
Authors:Slavik, K.M, Ragucci, A.E, Kranzusch, P.J.
Deposit date:2021-05-17
Release date:2021-07-21
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2 Å)
Cite:cGAS-like receptors sense RNA and control 3'2'-cGAMP signalling in Drosophila.
Nature, 597, 2021
7RWS
DownloadVisualize
BU of 7rws by Molmil
Structure of SAVED domain of Cap5 from Lactococcus lactis in complex with cGAMP
Descriptor: 3'2'-cGAMP, SAVED domain-containing protein
Authors:Huang, R.H, Chakravarti, A, Fatma, S.
Deposit date:2021-08-20
Release date:2021-11-10
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Molecular mechanisms of the CdnG-Cap5 antiphage defense system employing 3',2'-cGAMP as the second messenger.
Nat Commun, 12, 2021
6E68
DownloadVisualize
BU of 6e68 by Molmil
NAMPT co-crystal with inhibitor compound 2
Descriptor: (2E)-N-{4-[1-(3-aminobenzene-1-carbonyl)piperidin-4-yl]butyl}-3-(pyridin-3-yl)prop-2-enamide, Nicotinamide phosphoribosyltransferase, PHOSPHATE ION
Authors:Waight, A.B, Neumann, C.S.
Deposit date:2018-07-24
Release date:2018-08-08
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:NAMPT co-crystal with inhibitor compound 2
to be published
7RQD
DownloadVisualize
BU of 7rqd by Molmil
Crystal structure of the Thermus thermophilus 70S ribosome in complex with protein Y, A-site deacylated tRNA analog CACCA, P-site MTI-tripeptidyl-tRNA analog ACCA-ITM, and chloramphenicol at 2.50A resolution
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 16S Ribosomal RNA, 23S Ribosomal RNA, ...
Authors:Syroegin, E.A, Flemmich, L, Klepacki, D, Vazquez-Laslop, N, Micura, R, Polikanov, Y.S.
Deposit date:2021-08-06
Release date:2022-01-26
Last modified:2025-03-19
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis for the context-specific action of the classic peptidyl transferase inhibitor chloramphenicol.
Nat.Struct.Mol.Biol., 29, 2022
6X80
DownloadVisualize
BU of 6x80 by Molmil
Structure of the Campylobacter jejuni G508A Flagellar Filament
Descriptor: 5,7-diamino-3,5,7,9-tetradeoxy-L-glycero-alpha-L-manno-non-2-ulopyranosonic acid, Flagellin A
Authors:Kreutzberger, M.A.B, Wang, F, Egelman, E.H.
Deposit date:2020-06-01
Release date:2020-07-08
Last modified:2025-06-04
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Atomic structure of the Campylobacter jejuni flagellar filament reveals how epsilon Proteobacteria escaped Toll-like receptor 5 surveillance.
Proc.Natl.Acad.Sci.USA, 117, 2020

238582

數據於2025-07-09公開中

PDB statisticsPDBj update infoContact PDBjnumon