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3KLR
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BU of 3klr by Molmil
Bovine H-protein at 0.88 angstrom resolution
Descriptor: GLYCEROL, Glycine cleavage system H protein, SULFATE ION
Authors:Higashiura, A, Kurakane, T, Matsuda, M, Suzuki, M, Inaka, K, Sato, M, Tanaka, H, Fujiwara, K, Nakagawa, A.
Deposit date:2009-11-09
Release date:2010-06-09
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (0.88 Å)
Cite:High-resolution X-ray crystal structure of bovine H-protein at 0.88 A resolution
Acta Crystallogr.,Sect.D, 66, 2010
5W3F
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BU of 5w3f by Molmil
Yeast tubulin polymerized with GTP in vitro
Descriptor: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Howes, S.C, Geyer, E.A, LaFrance, B, Zhang, R, Kellogg, E.H, Westermann, S, Rice, L.M, Nogales, E.
Deposit date:2017-06-07
Release date:2017-07-19
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structural differences between yeast and mammalian microtubules revealed by cryo-EM.
J. Cell Biol., 216, 2017
2LP8
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BU of 2lp8 by Molmil
SOLUTION STRUCTURE OF AN APOPTOSIS ACTIVATING PHOTOSWITCHABLE BAK PEPTIDE BOUND to BCL-XL
Descriptor: 3,3'-(E)-diazene-1,2-diylbis{6-[(chloroacetyl)amino]benzenesulfonic acid}, Bcl-2 homologous antagonist/killer, Bcl-2-like protein 1
Authors:Wysoczanski, P, Mart, R.J, Loveridge, J.E, Williams, C, Whittaker, S.B.-M, Crump, M.P, Allemann, R.K.
Deposit date:2012-02-03
Release date:2012-04-18
Last modified:2021-08-18
Method:SOLUTION NMR
Cite:NMR Solution Structure of a Photoswitchable Apoptosis Activating Bak Peptide Bound to Bcl-x(L).
J.Am.Chem.Soc., 134, 2012
4O2C
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BU of 4o2c by Molmil
An Nt-acetylated peptide complexed with HLA-B*3901
Descriptor: Beta-2-microglobulin, HLA class I histocompatibility antigen, B-39 alpha chain, ...
Authors:Sun, M, Liu, J, Qi, J, Tefsen, B, Shi, Y, Yan, J, Gao, G.F.
Deposit date:2013-12-17
Release date:2014-07-23
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.802 Å)
Cite:N alpha-terminal acetylation for T cell recognition: molecular basis of MHC class I-restricted n alpha-acetylpeptide presentation
J.Immunol., 192, 2014
2FZ1
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BU of 2fz1 by Molmil
Structure of Empty Head Turnip Yellow Mosaic Virus (ATC) at 100 K
Descriptor: Coat protein
Authors:Larson, S.B, Lucas, R.W, McPherson, A.
Deposit date:2006-02-08
Release date:2006-02-21
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:The RNA of turnip yellow mosaic virus exhibits icosahedral order.
Virology, 334, 2005
3KPC
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BU of 3kpc by Molmil
Crystal Structure of the CBS domain pair of protein MJ0100 in complex with 5 -methylthioadenosine and S-adenosyl-L-methionine
Descriptor: 5'-DEOXY-5'-METHYLTHIOADENOSINE, S-ADENOSYLMETHIONINE, Uncharacterized protein MJ0100
Authors:Lucas, M, Oyenarte, I, Garcia, I.G, Arribas, E.A, Encinar, J.A, Kortazar, D, Fernandez, J.A, Mato, J.M, Martinez-Chantar, M.L, Martinez-Cruz, L.A.
Deposit date:2009-11-16
Release date:2010-01-12
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:Binding of S-Methyl-5'-Thioadenosine and S-Adenosyl-l-Methionine to Protein MJ0100 Triggers an Open-to-Closed Conformational Change in Its CBS Motif Pair.
J.Mol.Biol., 396, 2010
3KPU
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BU of 3kpu by Molmil
Crystal Structure of hPNMT in Complex AdoHcy and 4-quinolinol
Descriptor: Phenylethanolamine N-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE, quinolin-4-ol
Authors:Drinkwater, N, Martin, J.L.
Deposit date:2009-11-17
Release date:2010-09-29
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Fragment-based screening by X-ray crystallography, MS and isothermal titration calorimetry to identify PNMT (phenylethanolamine N-methyltransferase) inhibitors.
Biochem.J., 431, 2010
5VNO
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BU of 5vno by Molmil
Crystal structure of Sec23a/Sec24a/Sec22
Descriptor: Protein transport protein Sec23A, Protein transport protein Sec24A, Vesicle-trafficking protein SEC22b, ...
Authors:Ma, W, Goldberg, J.
Deposit date:2017-05-01
Release date:2017-07-05
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.905 Å)
Cite:ER retention is imposed by COPII protein sorting and attenuated by 4-phenylbutyrate.
Elife, 6, 2017
2G06
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BU of 2g06 by Molmil
X-ray structure of mouse pyrimidine 5'-nucleotidase type 1, with bound magnesium(II)
Descriptor: Cytosolic 5'-nucleotidase III, MAGNESIUM ION, PIPERAZINE-N,N'-BIS(2-ETHANESULFONIC ACID)
Authors:Bitto, E, Bingman, C.A, Wesenberg, G.E, Phillips Jr, G.N, Center for Eukaryotic Structural Genomics (CESG)
Deposit date:2006-02-11
Release date:2006-04-04
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structure of pyrimidine 5'-nucleotidase type 1. Insight into mechanism of action and inhibition during lead poisoning.
J.Biol.Chem., 281, 2006
3KR0
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BU of 3kr0 by Molmil
Crystal Structure of hPNMT in Complex AdoHcy and 2-amino-1H-benzo[d]imidazol-6-ol
Descriptor: 2-AMINO-5-HYDROXY-BENZIMIDAZOLE, Phenylethanolamine N-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Drinkwater, N, Martin, J.L.
Deposit date:2009-11-17
Release date:2010-09-29
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Fragment-based screening by X-ray crystallography, MS and isothermal titration calorimetry to identify PNMT (phenylethanolamine N-methyltransferase) inhibitors.
Biochem.J., 431, 2010
3KQK
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BU of 3kqk by Molmil
Three Conformational Snapshots of the Hepatitis C Virus NS3 Helicase Reveal a Ratchet Translocation Mechanism
Descriptor: 5'-D(*TP*TP*TP*TP*TP*T)-3', Serine protease/NTPase/helicase NS3
Authors:Gu, M, Rice, C.M.
Deposit date:2009-11-17
Release date:2010-01-26
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Three conformational snapshots of the hepatitis C virus NS3 helicase reveal a ratchet translocation mechanism.
Proc.Natl.Acad.Sci.USA, 107, 2010
4O32
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BU of 4o32 by Molmil
Structure of a malarial protein
Descriptor: CHLORIDE ION, Thioredoxin
Authors:Egea, P.F, Koehl, A, Peng, M, Cascio, D.
Deposit date:2013-12-17
Release date:2014-12-24
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.196 Å)
Cite:Crystal structure and solution characterization of the thioredoxin-2 from Plasmodium falciparum, a constituent of an essential parasitic protein export complex.
Biochem.Biophys.Res.Commun., 456, 2015
3KQT
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BU of 3kqt by Molmil
Crystal Structure of hPNMT in Complex AdoHcy and 2-Amino-1-methylbenzimidazole
Descriptor: 1-methyl-1H-benzimidazol-2-amine, Phenylethanolamine N-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Drinkwater, N, Martin, J.L.
Deposit date:2009-11-17
Release date:2010-09-29
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.399 Å)
Cite:Fragment-based screening by X-ray crystallography, MS and isothermal titration calorimetry to identify PNMT (phenylethanolamine N-methyltransferase) inhibitors.
Biochem.J., 431, 2010
4O3F
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BU of 4o3f by Molmil
Crystal Structure of mouse PGK1 3PG and terazosin(TZN) ternary complex
Descriptor: 3-PHOSPHOGLYCERIC ACID, Phosphoglycerate kinase 1, [4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl][(2R)-tetrahydrofuran-2-yl]methanone
Authors:Li, X.L, Finci, I.L, Wang, J.H.
Deposit date:2013-12-18
Release date:2014-10-29
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.106 Å)
Cite:Terazosin activates Pgk1 and Hsp90 to promote stress resistance.
Nat.Chem.Biol., 11, 2015
2FQZ
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BU of 2fqz by Molmil
Metal-depleted Ecl18kI in complex with uncleaved DNA
Descriptor: DNA STRAND 1, DNA STRAND 2, R.Ecl18kI
Authors:Bochtler, M, Szczepanowski, R.H, Tamulaitis, G, Grazulis, S, Czapinska, H, Manakova, E, Siksnys, V.
Deposit date:2006-01-18
Release date:2006-06-20
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:Nucleotide flips determine the specificity of the Ecl18kI restriction endonuclease
Embo J., 25, 2006
7SI3
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BU of 7si3 by Molmil
Consensus structure of ATP7B
Descriptor: MAGNESIUM ION, P-type Cu(+) transporter, TETRAFLUOROALUMINATE ION
Authors:Bitter, R.M, Oh, S.C, Hite, R.K, Yuan, P.
Deposit date:2021-10-12
Release date:2022-03-16
Method:ELECTRON MICROSCOPY (3.19 Å)
Cite:Structure of the Wilson disease copper transporter ATP7B.
Sci Adv, 8, 2022
4NUV
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BU of 4nuv by Molmil
Heterotetramer structure of Region II from Plasmodium vivax Duffy Binding Protein (PvDBP) bound to the ectodomain of the Duffy Antigen Receptor for Chemokines (DARC)
Descriptor: Duffy antigen/chemokine receptor, Duffy receptor, GLYCEROL
Authors:Tolia, N.H.
Deposit date:2013-12-04
Release date:2014-02-05
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Red Blood Cell Invasion by Plasmodium vivax: Structural Basis for DBP Engagement of DARC.
Plos Pathog., 10, 2014
3KTW
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BU of 3ktw by Molmil
Crystal structure of the SRP19/S-domain SRP RNA complex of Sulfolobus solfataricus
Descriptor: MAGNESIUM ION, POTASSIUM ION, SRP RNA, ...
Authors:Wild, K, Bange, G, Bozkurt, G, Sinning, I.
Deposit date:2009-11-26
Release date:2010-02-16
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural insights into the assembly of the human and archaeal signal recognition particles.
Acta Crystallogr.,Sect.D, 66, 2010
5VL7
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BU of 5vl7 by Molmil
PCSK9 complex with Fab33
Descriptor: Fab33 heavy chain, Fab33 light chain, Proprotein convertase subtilisin/kexin type 9
Authors:Eigenbrot, C, Shia, S.
Deposit date:2017-04-25
Release date:2017-08-16
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Discovery of a cryptic peptide-binding site on PCSK9 and design of antagonists.
Nat. Struct. Mol. Biol., 24, 2017
3KW9
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BU of 3kw9 by Molmil
X-ray structure of Cathepsin K covalently bound to a triazine ligand
Descriptor: 4-(cyclohexylamino)-6-piperazin-1-yl-1,3,5-triazine-2-carbonitrile, Cathepsin K, trifluoroacetic acid
Authors:Uitdehaag, J.C.M, van Zeeland, M.
Deposit date:2009-12-01
Release date:2010-03-02
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Design and optimization of a series of novel 2-cyano-pyrimidines as cathepsin K inhibitors.
Bioorg.Med.Chem.Lett., 20, 2010
7SB2
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BU of 7sb2 by Molmil
Structure of the periplasmic domain of GldM from Capnocytophaga canimorsus
Descriptor: GldM
Authors:Hennell James, R, Deme, J.C, Lea, S.M.
Deposit date:2021-09-23
Release date:2022-03-23
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structures of the Type IX Secretion/Gliding Motility Motor from across the Phylum Bacteroidetes.
Mbio, 13, 2022
4NXK
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BU of 4nxk by Molmil
Crystal structure of Abp-D197A, a catalytic mutant of a GH27-b-L-arabinopyranosidase from Geobacillus stearothermophilus
Descriptor: Abp, a GH27 beta-L-arabinopyranosidase, CITRIC ACID, ...
Authors:Lansky, S, Solomon, H.V, Salama, R, Belrhali, H, Shoham, Y, Shoham, G.
Deposit date:2013-12-09
Release date:2014-12-03
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure-specificity relationships in Abp, a GH27 beta-L-arabinopyranosidase from Geobacillus stearothermophilus T6
Acta Crystallogr.,Sect.D, 70, 2014
7SAT
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BU of 7sat by Molmil
Structure of PorLM, the proton-powered motor that drives Type IX protein secretion
Descriptor: Por secretion system protein porL/gldL, Por secretion system protein porM/gldM
Authors:Hennell James, R, Deme, J.C, Lea, S.M.
Deposit date:2021-09-23
Release date:2022-03-23
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structures of the Type IX Secretion/Gliding Motility Motor from across the Phylum Bacteroidetes.
Mbio, 13, 2022
3KWZ
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BU of 3kwz by Molmil
Cathepsin K in complex with a non-selective 2-cyano-pyrimidine inhibitor
Descriptor: 4-(3-piperidin-1-ylpropyl)-6-[3-(trifluoromethyl)phenyl]pyrimidine-2-carbonitrile, Cathepsin K, SULFATE ION
Authors:Fradera, X, Uitdehaag, J.C.M, van Zeeland, M.
Deposit date:2009-12-02
Release date:2010-03-02
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.49 Å)
Cite:Design and optimization of a series of novel 2-cyano-pyrimidines as cathepsin K inhibitors
Bioorg.Med.Chem.Lett., 20, 2010
5VNF
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BU of 5vnf by Molmil
Crystal structure of Sec23a/Sec24a/Sec22 complexed with a C-terminal VV sorting motif
Descriptor: C-terminal VV Sorting motif: VAL-THR-SER-VAL-VAL, Protein transport protein Sec23A, Protein transport protein Sec24A, ...
Authors:Ma, W, Goldberg, J.
Deposit date:2017-04-30
Release date:2017-07-05
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.407 Å)
Cite:ER retention is imposed by COPII protein sorting and attenuated by 4-phenylbutyrate.
Elife, 6, 2017

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數據於2024-09-04公開中

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