2LP8

SOLUTION STRUCTURE OF AN APOPTOSIS ACTIVATING PHOTOSWITCHABLE BAK PEPTIDE BOUND to BCL-XL

Summary for 2LP8

• Entry DOI: 10.2210/pdb2lp8/pdb
• Related: 2LPC
• NMR Information: BMRB: 18238
• Descriptor: Bcl-2-like protein 1, Bcl-2 homologous antagonist/killer, 3,3'-(E)-diazene-1,2-diylbis{6-[(chloroacetyl)amino]benzenesulfonic acid} (3 entities in total)
• Functional Keywords: apoptosis, azobenzene, photoswitch, photocontrol, apoptosis inhibitor, apoptosis-apoptosis activator complex, apoptosis/apoptosis activator
• Biological source: Homo sapiens (human); More
• Cellular location: Mitochondrion membrane; Single-pass membrane protein: Q07817; Mitochondrion membrane; Single-pass membrane protein (Potential): Q16611
• Total number of polymer chains: 2
• Total formula weight: 23629.80

Authors

Wysoczanski, P.,Mart, R.J.,Loveridge, J.E.,Williams, C.,Whittaker, S.B.-M.,Crump, M.P.,Allemann, R.K. (deposition date: 2012-02-03, release date: 2012-04-18, Last modification date: 2021-08-18)

• Primary citation: Wysoczanski, P.,Mart, R.J.,Loveridge, E.J.,Williams, C.,Whittaker, S.B.,Crump, M.P.,Allemann, R.K.; NMR Solution Structure of a Photoswitchable Apoptosis Activating Bak Peptide Bound to Bcl-x(L).; J.Am.Chem.Soc., 134:7644-7647, 2012; PubMed: 22515821; DOI: 10.1021/ja302390a

Experimental method

SOLUTION NMR