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1EUQ
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BU of 1euq by Molmil
CRYSTAL STRUCTURE OF GLUTAMINYL-TRNA SYNTHETASE COMPLEXED WITH A TRNA-GLN MUTANT AND AN ACTIVE-SITE INHIBITOR
Descriptor: 5'-O-[N-(L-GLUTAMINYL)-SULFAMOYL]ADENOSINE, GLUTAMINYL TRNA, GLUTAMINYL-TRNA SYNTHETASE
Authors:Sherlin, L.D, Bullock, T.L, Newberry, K.J, Lipman, R.S.A, Hou, Y.-M, Beijer, B, Sproat, B.S, Perona, J.J.
Deposit date:2000-04-17
Release date:2000-06-04
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Influence of transfer RNA tertiary structure on aminoacylation efficiency by glutaminyl and cysteinyl-tRNA synthetases.
J.Mol.Biol., 299, 2000
1FDI
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BU of 1fdi by Molmil
OXIDIZED FORM OF FORMATE DEHYDROGENASE H FROM E. COLI COMPLEXED WITH THE INHIBITOR NITRITE
Descriptor: 2-AMINO-5,6-DIMERCAPTO-7-METHYL-3,7,8A,9-TETRAHYDRO-8-OXA-1,3,9,10-TETRAAZA-ANTHRACEN-4-ONE GUANOSINE DINUCLEOTIDE, FORMATE DEHYDROGENASE H, IRON/SULFUR CLUSTER, ...
Authors:Sun, P.D, Boyington, J.C.
Deposit date:1997-01-28
Release date:1997-08-20
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal structure of formate dehydrogenase H: catalysis involving Mo, molybdopterin, selenocysteine, and an Fe4S4 cluster.
Science, 275, 1997
1FDO
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BU of 1fdo by Molmil
OXIDIZED FORM OF FORMATE DEHYDROGENASE H FROM E. COLI
Descriptor: 2-AMINO-5,6-DIMERCAPTO-7-METHYL-3,7,8A,9-TETRAHYDRO-8-OXA-1,3,9,10-TETRAAZA-ANTHRACEN-4-ONE GUANOSINE DINUCLEOTIDE, FORMATE DEHYDROGENASE H, IRON/SULFUR CLUSTER, ...
Authors:Sun, P.D, Boyington, J.C.
Deposit date:1997-01-27
Release date:1997-08-20
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of formate dehydrogenase H: catalysis involving Mo, molybdopterin, selenocysteine, and an Fe4S4 cluster.
Science, 275, 1997
3UAK
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BU of 3uak by Molmil
Crystal Structure of De Novo designed cysteine esterase ECH14, Northeast Structural Genomics Consortium Target OR54
Descriptor: De Novo designed cysteine esterase ECH14
Authors:Kuzin, A, Su, M, Seetharaman, J, Sahdev, S, Xiao, R, Ciccosanti, C, Richter, F, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Baker, D, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG)
Deposit date:2011-10-21
Release date:2011-12-07
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (3.232 Å)
Cite:Computational design of catalytic dyads and oxyanion holes for ester hydrolysis.
J.Am.Chem.Soc., 134, 2012
1M9O
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BU of 1m9o by Molmil
NMR structure of the first Zinc Binding domain of Nup475/TTP/TIS11
Descriptor: Tristetraproline, ZINC ION
Authors:Amann, B.T, Worthington, M.T, Berg, J.M.
Deposit date:2002-07-29
Release date:2003-06-03
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:A Cys3His Zinc-Binding Domain from Nup475/Tristetraproline: a Novel Fold with a Disklike Structure
Biochemistry, 42, 2003
3U1O
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BU of 3u1o by Molmil
THREE DIMENSIONAL STRUCTURE OF DE NOVO DESIGNED CYSTEINE ESTERASE ECH19, Northeast Structural Genomics Consortium Target OR49
Descriptor: De Novo design cysteine esterase ECH19, SODIUM ION, SULFATE ION
Authors:Kuzin, A, Su, M, Lew, S, Forouhar, F, Seetharaman, J, Daya, P, Xiao, R, Ciccosanti, C, Richter, F, Everett, J.K, Acton, T.B, Baker, D, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG)
Deposit date:2011-09-30
Release date:2011-10-26
Last modified:2024-11-27
Method:X-RAY DIFFRACTION (2.494 Å)
Cite:Computational design of catalytic dyads and oxyanion holes for ester hydrolysis.
J.Am.Chem.Soc., 134, 2012
3U1V
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BU of 3u1v by Molmil
X-ray Structure of De Novo design cysteine esterase FR29, Northeast Structural Genomics Consortium Target OR52
Descriptor: De Novo design cysteine esterase FR29
Authors:Kuzin, A, Su, M, Vorobiev, S.M, Seetharaman, J, Patel, D, Xiao, R, Ciccosanti, C, Richter, F, Everett, J.K, Acton, T.B, Baker, D, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG)
Deposit date:2011-09-30
Release date:2011-12-07
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.797 Å)
Cite:Computational design of catalytic dyads and oxyanion holes for ester hydrolysis.
J.Am.Chem.Soc., 134, 2012
3BWK
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BU of 3bwk by Molmil
Crystal Structure of Falcipain-3 with Its inhibitor, K11017
Descriptor: Cysteine protease falcipain-3, N~2~-(morpholin-4-ylcarbonyl)-N-[(3S)-1-phenyl-5-(phenylsulfonyl)pentan-3-yl]-L-leucinamide, SULFATE ION
Authors:Kerr, I, Lee, J.H, Brinen, L.S.
Deposit date:2008-01-09
Release date:2009-01-20
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (2.42 Å)
Cite:Vinyl sulfones as antiparasitic agents and a structural basis for drug design.
J.Biol.Chem., 284, 2009
7YEO
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BU of 7yeo by Molmil
Crystal Structure of cystathionine gamma-synthase-like protein C23A1.14c
Descriptor: MAGNESIUM ION, PYRIDOXAL-5'-PHOSPHATE, Uncharacterized trans-sulfuration enzyme C23A1.14c
Authors:Zhang, S.J.
Deposit date:2022-07-06
Release date:2023-01-11
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal Structure of cystathionine gamma-synthase-like protein C23A1.14c
To Be Published
2OE1
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BU of 2oe1 by Molmil
Crystal Structure of Mitochondrial Thioredoxin 3 from Saccharomyces cerevisiae (reduced form)
Descriptor: SULFATE ION, Thioredoxin-3
Authors:Bao, R, Zhang, Y.R, Zhou, C.Z, Chen, Y.X.
Deposit date:2006-12-28
Release date:2008-01-08
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural and mechanistic analyses of yeast mitochondrial thioredoxin Trx3 reveal putative function of its additional cysteine residues
Biochim.Biophys.Acta, 1794, 2009
8V57
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BU of 8v57 by Molmil
Complex of murine cathepsin K with bound cystatin C inhibitor
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Cathepsin K, ...
Authors:Pedersen, L.C, Xu, D.
Deposit date:2023-11-30
Release date:2024-10-09
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Heparan sulfate selectively inhibits the collagenase activity of cathepsin K.
Matrix Biol., 129, 2024
2OE0
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BU of 2oe0 by Molmil
Crystal Structure of Mitochondrial Thioredoxin 3 from Saccharomyces cerevisiae
Descriptor: Thioredoxin-3
Authors:Bao, R, Zhang, Y.R, Zhou, C.Z, Chen, Y.X.
Deposit date:2006-12-27
Release date:2008-01-08
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural and mechanistic analyses of yeast mitochondrial thioredoxin Trx3 reveal putative function of its additional cysteine residues
Biochim.Biophys.Acta, 1794, 2009
2OE3
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BU of 2oe3 by Molmil
Crystal Structure of Mitochondrial Thioredoxin 3 from Saccharomyces cerevisiae (oxidized form)
Descriptor: Thioredoxin-3
Authors:Bao, R, Zhang, Y.R, Zhou, C.Z, Chen, Y.X.
Deposit date:2006-12-28
Release date:2008-01-08
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural and mechanistic analyses of yeast mitochondrial thioredoxin Trx3 reveal putative function of its additional cysteine residues
Biochim.Biophys.Acta, 1794, 2009
1B8T
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BU of 1b8t by Molmil
SOLUTION STRUCTURE OF THE CHICKEN CRP1
Descriptor: PROTEIN (CRP1), ZINC ION
Authors:Yao, X, Perez-Alvarado, G.C, Louis, H.A, Pomies, P, Hatt, C, Summers, M.F, Beckerle, M.C.
Deposit date:1999-02-02
Release date:1999-05-06
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Solution structure of the chicken cysteine-rich protein, CRP1, a double-LIM protein implicated in muscle differentiation.
Biochemistry, 38, 1999
1G5Q
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BU of 1g5q by Molmil
EPID H67N COMPLEXED WITH SUBSTRATE PEPTIDE DSYTC
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, EPIDERMIN MODIFYING ENZYME EPID, FLAVIN MONONUCLEOTIDE, ...
Authors:Blaesse, M, Kupke, T, Huber, R, Steinbacher, S.
Deposit date:2000-11-02
Release date:2001-05-02
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.57 Å)
Cite:Crystal structure of the peptidyl-cysteine decarboxylase EpiD complexed with a pentapeptide substrate.
EMBO J., 19, 2000
6P0W
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BU of 6p0w by Molmil
LsfA from P. aeruginosa, a 1-Cys Prx in reduced form
Descriptor: CHLORIDE ION, Putative thiol-specific antioxidant protein
Authors:AIeixo-Silva, R.L, Domingos, R.M, Netto, L.E.S.
Deposit date:2019-05-17
Release date:2020-05-13
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure of LsfA, a 1-Cys Prx in reduced form
To Be Published
9CKY
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BU of 9cky by Molmil
X-ray diffraction structure of papain co-crystallized with novel biosynthetic inhibitor amine-65
Descriptor: (3S)-4-({(1S)-2-[(8-aminooctyl)amino]-1-cyclobutyl-2-oxoethyl}amino)-3-hydroxy-4-oxobutanoic acid, METHANOL, Papain
Authors:Vlahakis, N.W, Liu, M, Tang, Y, Rodriguez, J.A.
Deposit date:2024-07-10
Release date:2025-06-04
Last modified:2025-06-11
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Enzymatic combinatorial synthesis of E-64 and related cysteine protease inhibitors.
Nat.Chem.Biol., 2025
9CKT
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BU of 9ckt by Molmil
X-ray diffraction structure of papain co-crystallized with E-64
Descriptor: METHANOL, N-[N-[1-HYDROXYCARBOXYETHYL-CARBONYL]LEUCYLAMINO-BUTYL]-GUANIDINE, Papain
Authors:Vlahakis, N.W, Rodriguez, J.A.
Deposit date:2024-07-09
Release date:2025-06-04
Last modified:2025-06-11
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Enzymatic combinatorial synthesis of E-64 and related cysteine protease inhibitors.
Nat.Chem.Biol., 2025
9CKW
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BU of 9ckw by Molmil
X-ray diffraction structure of papain co-crystallized with E-64D
Descriptor: METHANOL, Papain, ethyl (3S)-3-hydroxy-4-({(2S)-4-methyl-1-[(3-methylbutyl)amino]-1-oxopentan-2-yl}amino)-4-oxobutanoate
Authors:Vlahakis, N.W, Rodriguez, J.A.
Deposit date:2024-07-10
Release date:2025-06-04
Last modified:2025-06-11
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Enzymatic combinatorial synthesis of E-64 and related cysteine protease inhibitors.
Nat.Chem.Biol., 2025
5WLW
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BU of 5wlw by Molmil
Crystal Structure of the Human Mitochondrial Cysteine Desulfurase with active Cysteine Loop within ISCU1 active site, coordinating Zn ion. Complexed with human ISD11 and E. coli ACP1 at 3.3A.
Descriptor: Acyl carrier protein, Cysteine desulfurase, mitochondrial, ...
Authors:Boniecki, M.T, Cygler, M.
Deposit date:2017-07-27
Release date:2017-11-15
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.317 Å)
Cite:Structure and functional dynamics of the mitochondrial Fe/S cluster synthesis complex.
Nat Commun, 8, 2017
9EG7
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BU of 9eg7 by Molmil
X-ray diffraction structure of papain co-crystallized with E64-C
Descriptor: N-[1-HYDROXYCARBOXYETHYL-CARBONYL]LEUCYLAMINO-2-METHYL-BUTANE, Papain
Authors:Vlahakis, N.W, Rodriguez, J.A, Tang, Y.
Deposit date:2024-11-20
Release date:2025-06-04
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Enzymatic combinatorial synthesis of E-64 and related cysteine protease inhibitors.
Nat.Chem.Biol., 2025
5WKP
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BU of 5wkp by Molmil
Crystal Structure of the Human mitochondrial Cysteine Desulfurase in complex with ISD11 and Iron-Sulfur Cluster Scaffold Protein ISCU1, and E. coli ACP1 protein at 3.15A
Descriptor: Acyl carrier protein, Cysteine desulfurase, mitochondrial, ...
Authors:Boniecki, M.T, Cygler, M.
Deposit date:2017-07-25
Release date:2017-11-15
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:Structure and functional dynamics of the mitochondrial Fe/S cluster synthesis complex.
Nat Commun, 8, 2017
5WGB
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BU of 5wgb by Molmil
Crystal Structure of the Human mitochondrial Cysteine Desulfurase in complex with ISD11 and E. coli ACP1 protein at 2.75A
Descriptor: Acyl carrier protein, Cysteine desulfurase, mitochondrial, ...
Authors:Boniecki, M.T, Cygler, M.
Deposit date:2017-07-13
Release date:2017-07-26
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Structure and functional dynamics of the mitochondrial Fe/S cluster synthesis complex.
Nat Commun, 8, 2017
1CB5
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BU of 1cb5 by Molmil
HUMAN BLEOMYCIN HYDROLASE.
Descriptor: BLEOMYCIN HYDROLASE
Authors:O'Farrell, P.A, Gonzalez, F, Zheng, W, Johnston, S.A, Joshua-Tor, L.
Deposit date:1999-03-01
Release date:2000-03-01
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.59 Å)
Cite:Crystal structure of human bleomycin hydrolase, a self-compartmentalizing cysteine protease.
Structure Fold.Des., 7, 1999
4DVH
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BU of 4dvh by Molmil
Crystal structure of Trypanosoma cruzi mitochondrial iron superoxide dismutase
Descriptor: FE (III) ION, Superoxide dismutase
Authors:Larrieux, N, Buschiazzo, A.
Deposit date:2012-02-23
Release date:2013-03-27
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.23 Å)
Cite:Structural and Molecular Basis of the Peroxynitrite-mediated Nitration and Inactivation of Trypanosoma cruzi Iron-Superoxide Dismutases (Fe-SODs) A and B: DISPARATE SUSCEPTIBILITIES DUE TO THE REPAIR OF TYR35 RADICAL BY CYS83 IN Fe-SODB THROUGH INTRAMOLECULAR ELECTRON TRANSFER.
J.Biol.Chem., 289, 2014

238582

數據於2025-07-09公開中

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