8QU1
| mt-LSU assembly intermediate in GTPBP8 knock-out cells, state 1 | Descriptor: | 16S ribosomal RNA, 39S ribosomal protein L10, mitochondrial, ... | Authors: | Valentin Gese, G, Cipullo, M, Rorbach, J, Hallberg, B.M. | Deposit date: | 2023-10-13 | Release date: | 2024-06-26 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (2.74 Å) | Cite: | GTPBP8 plays a role in mitoribosome formation in human mitochondria. Nat Commun, 15, 2024
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7PO3
| Human mitochondrial ribosome small subunit | Descriptor: | 12S mitochondrial rRNA, 28S ribosomal protein S10, mitochondrial, ... | Authors: | Itoh, Y, Khawaja, A, Rorbach, J, Amunts, A. | Deposit date: | 2021-09-08 | Release date: | 2022-06-15 | Last modified: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (2.92 Å) | Cite: | Mechanism of mitoribosomal small subunit biogenesis and preinitiation. Nature, 606, 2022
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7PNW
| Mouse mitochondrial ribosome small subunit lacking m5U modification | Descriptor: | 12S mitochondrial rRNA, 28S ribosomal protein S10, mitochondrial, ... | Authors: | Itoh, Y, Khawaja, A, Laptev, I, Sergiev, P, Rorbach, J, Amunts, A. | Deposit date: | 2021-09-08 | Release date: | 2022-06-15 | Last modified: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (3.09 Å) | Cite: | Mechanism of mitoribosomal small subunit biogenesis and preinitiation. Nature, 606, 2022
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7PO1
| Initiation complex of human mitochondrial ribosome small subunit with IF3 | Descriptor: | 12S mitochondrial rRNA, 28S ribosomal protein S10, mitochondrial, ... | Authors: | Itoh, Y, Khawaja, A, Rorbach, J, Amunts, A. | Deposit date: | 2021-09-08 | Release date: | 2022-06-15 | Last modified: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (2.92 Å) | Cite: | Mechanism of mitoribosomal small subunit biogenesis and preinitiation. Nature, 606, 2022
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3MWW
| Crystal structure of HCV NS5B polymerase | Descriptor: | 1-[2-(4-carboxypiperidin-1-yl)-2-oxoethyl]-3-cyclohexyl-2-furan-3-yl-1H-indole-6-carboxylic acid, Genome polyprotein, SULFATE ION | Authors: | Coulombe, R. | Deposit date: | 2010-05-06 | Release date: | 2010-10-27 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Importance of ligand bioactive conformation in the discovery of potent indole-diamide inhibitors of the hepatitis C virus NS5B. J.Am.Chem.Soc., 132, 2010
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8B8V
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7XWX
| Crystal structure of SARS-CoV-2 N-CTD | Descriptor: | Nucleoprotein, PHOSPHATE ION | Authors: | Luan, X.D, Li, X.M, Li, Y.F. | Deposit date: | 2022-05-27 | Release date: | 2023-02-08 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Antiviral drug design based on structural insights into the N-terminal domain and C-terminal domain of the SARS-CoV-2 nucleocapsid protein. Sci Bull (Beijing), 67, 2022
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5DZM
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1XNR
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1QJX
| HUMAN RHINOVIRUS 16 COAT PROTEIN IN COMPLEX WITH ANTIVIRAL COMPOUND WIN68934 | Descriptor: | 2,6-DIMETHYL-1-(3-[3-METHYL-5-ISOXAZOLYL]-PROPANYL)-4-[4-METHYL-2H-TETRAZOL-2-YL]-PHENOL, MYRISTIC ACID, PROTEIN VP1, ... | Authors: | Hadfield, A.T, Diana, G.D, Rossmann, M.G. | Deposit date: | 1999-07-06 | Release date: | 1999-07-20 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Analysis of Three Structurally Related Antiviral Compounds in Complex with Human Rhinovirus 16 Proc.Natl.Acad.Sci.USA, 96, 1999
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7MRX
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7XX1
| Crystal structure of SARS-CoV-2 N-NTD | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Nucleoprotein, ZINC ION | Authors: | Luan, X.D, Li, X.M, Li, Y.F. | Deposit date: | 2022-05-27 | Release date: | 2023-02-08 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Antiviral drug design based on structural insights into the N-terminal domain and C-terminal domain of the SARS-CoV-2 nucleocapsid protein. Sci Bull (Beijing), 67, 2022
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1QJU
| HUMAN RHINOVIRUS 16 COAT PROTEIN IN COMPLEX WITH ANTIVIRAL COMPOUND VP61209 | Descriptor: | 2,6-DIMETHYL-1-(3-[3-METHYL-5-ISOXAZOLYL]-PROPANYL)-4-[2N-METHYL-2H-TETRAZOL-5-YL]-PHENOL, MYRISTIC ACID, PROTEIN VP1, ... | Authors: | Hadfield, A.T, Minor, I, Diana, G.D, Rossmann, M.G. | Deposit date: | 1999-07-05 | Release date: | 1999-07-20 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Analysis of Three Structurally Related Antiviral Compounds in Complex with Human Rhinovirus 16 Proc.Natl.Acad.Sci.USA, 96, 1999
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1QJY
| HUMAN RHINOVIRUS 16 COAT PROTEIN IN COMPLEX WITH ANTIVIRAL COMPOUND VP65099 | Descriptor: | 2,6-DIMETHYL-1-(3-[3-METHYL-5-ISOXAZOLYL]-PROPANYL)-4-[2-METHYL-4-ISOXAZOLYL]-PHENOL, MYRISTIC ACID, PROTEIN VP1, ... | Authors: | Hadfield, A.T, Diana, G.D, Rossmann, M.G. | Deposit date: | 1999-07-06 | Release date: | 1999-07-20 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Analysis of Three Structurally Related Antiviral Compounds in Complex with Human Rhinovirus 16 Proc.Natl.Acad.Sci.USA, 96, 1999
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6AIX
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5W71
| X-ray structure of BtrR from Bacillus circulans in the presence of the 2-DOS external aldimine | Descriptor: | CHLORIDE ION, L-glutamine:2-deoxy-scyllo-inosose aminotransferase, PYRIDOXAL-5'-PHOSPHATE, ... | Authors: | Zachman-Brockmeyer, T.R, Thoden, J.B, Holden, H.M. | Deposit date: | 2017-06-19 | Release date: | 2017-07-12 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | The structure of RbmB from Streptomyces ribosidificus, an aminotransferase involved in the biosynthesis of ribostamycin. Protein Sci., 26, 2017
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5VTM
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5VU8
| TNA polymerase, closed ternary complex | Descriptor: | DNA polymerase, DNA template, DNA/TNA hybrid primer, ... | Authors: | Chim, N, Chaput, J.C. | Deposit date: | 2017-05-18 | Release date: | 2017-12-06 | Last modified: | 2017-12-13 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Structural basis for TNA synthesis by an engineered TNA polymerase. Nat Commun, 8, 2017
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6AIY
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5W21
| Crystal Structure of a 1:1:1 FGF23-FGFR1c-aKlotho Ternary Complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Fibroblast growth factor 23, Fibroblast growth factor receptor 1, ... | Authors: | Mohammadi, M. | Deposit date: | 2017-06-05 | Release date: | 2018-01-24 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | alpha-Klotho is a non-enzymatic molecular scaffold for FGF23 hormone signalling. Nature, 553, 2018
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7YSU
| Cryo-EM Structure of FGF23-FGFR3c-aKlotho-HS Quaternary Complex | Descriptor: | 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid, COPPER (II) ION, Fibroblast growth factor 23, ... | Authors: | Mohammadi, M, Chen, L. | Deposit date: | 2022-08-13 | Release date: | 2023-04-19 | Last modified: | 2023-07-05 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structural basis for FGF hormone signalling. Nature, 618, 2023
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7YSH
| Cryo-EM Structure of FGF23-FGFR1c-aKlotho-HS Quaternary Complex | Descriptor: | 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose, COPPER (II) ION, Fibroblast growth factor 23, ... | Authors: | Mohammadi, M, Chen, L. | Deposit date: | 2022-08-12 | Release date: | 2023-04-19 | Last modified: | 2023-07-05 | Method: | ELECTRON MICROSCOPY (2.74 Å) | Cite: | Structural basis for FGF hormone signalling. Nature, 618, 2023
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7YSW
| Cryo-EM Structure of FGF23-FGFR4-aKlotho-HS Quaternary Complex | Descriptor: | 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid, COPPER (II) ION, Fibroblast growth factor 23, ... | Authors: | Mohammadi, M, Chen, L. | Deposit date: | 2022-08-13 | Release date: | 2023-06-14 | Last modified: | 2023-07-05 | Method: | ELECTRON MICROSCOPY (3.03 Å) | Cite: | Structural basis for FGF hormone signalling. Nature, 618, 2023
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1X0T
| Crystal structure of ribonuclease P protein Ph1601p from Pyrococcus horikoshii OT3 | Descriptor: | Ribonuclease P protein component 4, ZINC ION | Authors: | Kakuta, Y, Ishimatsu, I, Numata, T, Kimura, K, Yao, M, Tanaka, I, Kimura, M. | Deposit date: | 2005-03-29 | Release date: | 2005-11-15 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Crystal Structure of a Ribonuclease P Protein Ph1601p from Pyrococcus horikoshii OT3: An Archaeal Homologue of Human Nuclear Ribonuclease P Protein Rpp21(,) Biochemistry, 44, 2005
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7AMV
| Atomic structure of the poxvirus transcription pre-initiation complex in the initially melted state | Descriptor: | ATP-dependent helicase VETFS, DNA-directed RNA polymerase, DNA-directed RNA polymerase 147 kDa polypeptide, ... | Authors: | Grimm, C, Bartuli, J, Fischer, U. | Deposit date: | 2020-10-09 | Release date: | 2021-10-06 | Last modified: | 2021-10-20 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Structural basis of the complete poxvirus transcription initiation process. Nat.Struct.Mol.Biol., 28, 2021
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