PDB: 72150 resultsInfo pagesStatus searchChemie searchBIRD

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3QO0	Monoclinic form of IgG1 Fab fragment (in complex with antigenic peptide) sharing same Fv as IgA Descriptor: Fab fragment of IMMUNOGLOBULIN G1 HEAVY CHAIN, Fab fragment of IMMUNOGLOBULIN G1 LIGHT CHAIN, GLYCEROL, ... Authors: Trajtenberg, F, Correa-Bove, A, Buschiazzo, A. Deposit date: 2011-02-09 Release date: 2012-02-15 Last modified: 2017-11-08 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Crystal structures of human IGA1 and IGG1 fab fragments sharing the same variable domains To be published
4BAZ	Structure of a putative epoxide hydrolase Q244E mutant from Pseudomonas aeruginosa. Descriptor: CHLORIDE ION, GLYCEROL, PROBABLE EPOXIDE HYDROLASE, ... Authors: Schmidberger, J.W, Schnell, R, Schneider, G. Deposit date: 2012-09-17 Release date: 2013-10-02 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (1.35 Å) Cite: Structure of a Putative Epoxide Hydrolase Q244E Mutant from Pseudomonas Aeruginosa To be Published
4BB5	Free-Wilson and Structural Approaches to Co-optimising Human and Rodent Isoform Potency for 11b-Hydroxysteroid Dehydrogenase Type 1 11b-HSD1 Inhibitors Descriptor: 4-cyclopentyl-N-[(1S,3R)-5-oxidanyl-2-adamantyl]-2-[[(3S)-oxolan-3-yl]amino]pyrimidine-5-carboxamide, CORTICOSTEROID 11-BETA-DEHYDROGENASE ISOZYME 1, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE Authors: Goldberg, F.W, Leach, A.G, Scott, J.S, Snelson, W.L, Groombridge, S.D, Donald, C.S, Bennett, S.N.L, Bodin, C, Morentin Gutierrez, P, Gyte, A.C. Deposit date: 2012-09-20 Release date: 2012-11-28 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Free-Wilson and Structural Approaches to Co-Optimising Human and Rodent Isoform Potency for 11Beta-Hydroxysteroid Dehydrogenase Type 1 (11Beta-Hsd1) Inhibitors J.Med.Chem., 55, 2012
4BB6	Free-Wilson and Structural Approaches to Co-optimising Human and Rodent Isoform Potency for 11b-Hydroxysteroid Dehydrogenase Type 1 11b-HSD1 Inhibitors Descriptor: 6-(4-methylpiperazin-1-yl)-N-[(1R,3S)-5-oxidanyl-2-adamantyl]-2-propylsulfanyl-pyridine-3-carboxamide, CHLORIDE ION, CORTICOSTEROID 11-BETA-DEHYDROGENASE ISOZYME 1, ... Authors: Goldberg, F.W, Leach, A.G, Scott, J.S, Snelson, W.L, Groombridge, S.D, Donald, C.S, Bennett, S.N.L, Bodin, C, Morentin Gutierrez, P, Gyte, A.C. Deposit date: 2012-09-20 Release date: 2012-11-28 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (2.55 Å) Cite: Free-Wilson and Structural Approaches to Co- Optimising Human and Rodent Isoform Potency for 11Beta-Hydroxysteroid Dehydrogenase Type 1 (11Beta-Hsd1) Inhibitors J.Med.Chem., 55, 2012
5UQO	Crystal structure of 2-methylcitrate synthase from Aspergillus fumigatus Descriptor: 2-methylcitrate synthase, mitochondrial Authors: Schlachter, C, Chruszcz, M. Deposit date: 2017-02-08 Release date: 2018-02-14 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Comparative studies of Aspergillus fumigatus 2-methylcitrate synthase and human citrate synthase. Biol.Chem., 400, 2019
5OA5	CELLOBIOHYDROLASE I (CEL7A) FROM HYPOCREA JECORINA WITH IMPROVED THERMAL STABILITY Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Exoglucanase 1, GLYCEROL Authors: Goedegebuur, F, Hansson, H, Karkehabadi, S, Mikkelsen, N, Stahlberg, J, Sandgren, M. Deposit date: 2017-06-20 Release date: 2017-09-06 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Improving the thermal stability of cellobiohydrolase Cel7A from Hypocrea jecorina by directed evolution. J. Biol. Chem., 292, 2017
5UQQ	Crystal structure of 2-methylcitrate synthase from Aspergillus fumigatus Descriptor: 2-methylcitrate synthase, mitochondrial, S,R MESO-TARTARIC ACID Authors: Schlachter, C, Chruszcz, M. Deposit date: 2017-02-08 Release date: 2018-02-14 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Comparative studies of Aspergillus fumigatus 2-methylcitrate synthase and human citrate synthase. Biol.Chem., 400, 2019
5NYP	Anbu from Hyphomicrobium sp. strain MC1 - SG: R32 Descriptor: Anbu, PHOSPHATE ION, SODIUM ION Authors: Vielberg, M.-T, Groll, M. Deposit date: 2017-05-11 Release date: 2017-05-24 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.9 Å) Cite: On the Trails of the Proteasome Fold: Structural and Functional Analysis of the Ancestral beta-Subunit Protein Anbu. J. Mol. Biol., 430, 2018
5NYF	Selenomethionine labelled Anbu (Gly-1) mutant from Hyphomicrobium sp. strain MC1 Descriptor: Anbu, PHOSPHATE ION, SODIUM ION Authors: Vielberg, M.-T, Groll, M. Deposit date: 2017-05-11 Release date: 2017-05-24 Last modified: 2018-03-07 Method: X-RAY DIFFRACTION (2.2 Å) Cite: On the Trails of the Proteasome Fold: Structural and Functional Analysis of the Ancestral beta-Subunit Protein Anbu. J. Mol. Biol., 430, 2018
5NYG	Anbu (Gly-1) mutant from Hyphomicrobium sp. strain MC1 - SG P2(1)2(1)2(1) Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Anbu Authors: Vielberg, M.-T, Groll, M. Deposit date: 2017-05-11 Release date: 2017-05-24 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (2.4 Å) Cite: On the Trails of the Proteasome Fold: Structural and Functional Analysis of the Ancestral beta-Subunit Protein Anbu. J. Mol. Biol., 430, 2018
5V60	Phospho-ERK2 bound to AMP-PCP Descriptor: GLYCEROL, MAGNESIUM ION, Mitogen-activated protein kinase 1, ... Authors: Lechtenberg, B.C, Riedl, S.J. Deposit date: 2017-03-15 Release date: 2017-07-26 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (2.18 Å) Cite: Structure-Guided Strategy for the Development of Potent Bivalent ERK Inhibitors. ACS Med Chem Lett, 8, 2017
5V62	Phospho-ERK2 bound to bivalent inhibitor SBP3 Descriptor: 5-(2-PHENYLPYRAZOLO[1,5-A]PYRIDIN-3-YL)-1H-PYRAZOLO[3,4-C]PYRIDAZIN-3-AMINE, GLYCEROL, Mitogen-activated protein kinase 1, ... Authors: Lechtenberg, B.C, Riedl, S.J. Deposit date: 2017-03-15 Release date: 2017-07-26 Last modified: 2024-07-10 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Structure-Guided Strategy for the Development of Potent Bivalent ERK Inhibitors. ACS Med Chem Lett, 8, 2017
5V61	Phospho-ERK2 bound to bivalent inhibitor SBP2 Descriptor: 2-oxo-6,9,12,15-tetraoxa-3-azaoctadecan-18-oic acid, 5-(2-PHENYLPYRAZOLO[1,5-A]PYRIDIN-3-YL)-1H-PYRAZOLO[3,4-C]PYRIDAZIN-3-AMINE, GLYCEROL, ... Authors: Lechtenberg, B.C, Riedl, S.J. Deposit date: 2017-03-15 Release date: 2017-07-26 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Structure-Guided Strategy for the Development of Potent Bivalent ERK Inhibitors. ACS Med Chem Lett, 8, 2017
5TVP	SUMO2 bound to Mouse Tdp2 catalytic domain with a 5'-phosphorylated DNA ternary complex Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, DNA (5'-D(P*CP*CP*GP*AP*AP*TP*TP*CP*G)-3'), ... Authors: Schellenberg, M.J, Williams, R.S. Deposit date: 2016-11-09 Release date: 2017-10-11 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.399 Å) Cite: ZATT (ZNF451)-mediated resolution of topoisomerase 2 DNA-protein cross-links. Science, 357, 2017
5VAC	Crystal Structure of ATXR5 SET domain in complex with K36me3 histone H3 peptide Descriptor: DIMETHYL SULFOXIDE, Histone H3.2, Probable Histone-lysine N-methyltransferase ATXR5, ... Authors: Bergamin, E, Sarvan, S, Malette, J, Eram, M, Yeung, S, Mongeon, V, Joshi, M, Brunzelle, J.S, Michaels, S.D, Blais, A, Vedadi, M, Couture, J.F. Deposit date: 2017-03-24 Release date: 2017-04-19 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.949 Å) Cite: Molecular basis for the methylation specificity of ATXR5 for histone H3. Nucleic Acids Res., 45, 2017
5OPF	Structure of LPMO10B from from Micromonospora aurantiaca Descriptor: COPPER (II) ION, Chitin-binding domain 3 protein Authors: Forsberg, Z, Bissaro, B, Gullesen, J, Dalhus, B, Vaaje-Kolstad, G, Eijsink, V.G.H. Deposit date: 2017-08-09 Release date: 2017-12-13 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.081 Å) Cite: Structural determinants of bacterial lytic polysaccharide monooxygenase functionality. J. Biol. Chem., 293, 2018
5TVQ	Mouse Tdp2 catalytic domain bound to SUMO2 Descriptor: ACETATE ION, CALCIUM ION, Small ubiquitin-related modifier 2, ... Authors: Schellenberg, M.J, Williams, R.S. Deposit date: 2016-11-09 Release date: 2017-09-27 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.35 Å) Cite: ZATT (ZNF451)-mediated resolution of topoisomerase 2 DNA-protein cross-links. Science, 357, 2017
5VAH	Crystal structure of ATXR5 SET domain in complex with histone H3 di-methylated on R26 Descriptor: Histone H3.2, Probable Histone-lysine N-methyltransferase ATXR5, S-ADENOSYL-L-HOMOCYSTEINE Authors: Bergamin, E, Sarvan, S, Malette, J, Eram, M, Yeung, S, Mongeon, V, Joshi, M, Brunzelle, J.S, Michaels, S.D, Blais, A, Vedadi, M, Couture, J.-F. Deposit date: 2017-03-26 Release date: 2017-04-05 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Molecular basis for the methylation specificity of ATXR5 for histone H3. Nucleic Acids Res., 45, 2017
5VAB	Crystal structure of ATXR5 PHD domain in complex with histone H3 Descriptor: ATXR5 PHD domain, Histone H3 peptide, ZINC ION Authors: Bergamin, E, Sarvan, S, Malette, J, Eram, M, Yeung, S, Mongeon, V, Joshi, M, Brunzelle, J.S, Michaels, S.D, Blais, A, Vedadi, M, Couture, J.-F. Deposit date: 2017-03-24 Release date: 2017-04-19 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.702 Å) Cite: Molecular basis for the methylation specificity of ATXR5 for histone H3. Nucleic Acids Res., 45, 2017
5VA6	CRYSTAL STRUCTURE OF ATXR5 IN COMPLEX WITH HISTONE H3.1 MONO-METHYLATED ON R26 Descriptor: Histone H3.1, Probable Histone-lysine N-methyltransferase ATXR5, S-ADENOSYL-L-HOMOCYSTEINE Authors: Bergamin, E, Sarvan, S, Malette, J, Eram, M, Yeung, S, Mongeon, V, Joshi, M, Brunzelle, J.S, Michaels, S.D, Blais, A, Vedadi, M, Couture, J.-F. Deposit date: 2017-03-24 Release date: 2017-04-19 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Molecular basis for the methylation specificity of ATXR5 for histone H3. Nucleic Acids Res., 45, 2017
5VYB	Structure of the carbohydrate recognition domain of Dectin-2 complexed with a mammalian-type high mannose Man9GlcNAc2 oligosaccharide Descriptor: C-type lectin domain family 6 member A, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ... Authors: Feinberg, H, Jegouzo, S.A.F, Rex, M.J, Drickamer, K, Taylor, M.E, Weis, W.I. Deposit date: 2017-05-24 Release date: 2017-07-05 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Mechanism of pathogen recognition by human dectin-2. J. Biol. Chem., 292, 2017
2AIB	beta-cinnamomin in complex with ergosterol Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Beta-elicitin cinnamomin, ERGOSTEROL, ... Authors: Rodrigues, M.L, Archer, M, Martel, P, Miranda, S, Thomaz, M, Enguita, F.J, Baptista, R.P, Melo, E.P, Sousa, N, Cravador, A, Carrondo, M.A. Deposit date: 2005-07-29 Release date: 2006-01-17 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (1.1 Å) Cite: Crystal structures of the free and sterol-bound forms of beta-cinnamomin Biochim.Biophys.Acta, 1764, 2006
1LGL	Solution structure of HERG-specific scorpion toxin BeKm-1 Descriptor: BeKm-1 toxin Authors: Korolokova, Y.V, Bocharov, E.V, Angelo, K, Maslennikov, I.V, Grinenko, O.V, Lipkin, A.V, Nosireva, E.D, Pluzhnikov, K.A, Olesen, S.-P, Arseniev, A.S, Grishin, E.V. Deposit date: 2002-04-16 Release date: 2002-11-20 Last modified: 2022-02-23 Method: SOLUTION NMR Cite: New binding site on common molecular scaffold provides HERG channel specificity of scorpion toxin BeKm-1. J.Biol.Chem., 277, 2002
2N7G	Structure of the cyclic nucleotide-binding homology domain of the hERG channel Descriptor: Potassium voltage-gated channel subfamily H member 2 Authors: Li, Y, Ng, H, Li, Q, Kang, C. Deposit date: 2015-09-10 Release date: 2016-05-18 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: Structure of the Cyclic Nucleotide-Binding Homology Domain of the hERG Channel and Its Insight into Type 2 Long QT Syndrome Sci Rep, 6, 2016
1J5J	Solution structure of HERG-specific scorpion toxin BeKm-1 Descriptor: BeKm-1 toxin Authors: Korolokova, Y.V, Bocharov, E.V, Angelo, K, Maslennikov, I.V, Grinenko, O.V, Lipkin, A.V, Nosireva, E.D, Pluzhnikov, K.A, Olesen, S.-P, Arseniev, A.S, Grishin, E.V. Deposit date: 2002-04-16 Release date: 2002-11-20 Last modified: 2023-12-27 Method: SOLUTION NMR Cite: New binding site on common molecular scaffold provides HERG channel specificity of scorpion toxin BeKm-1. J.Biol.Chem., 277, 2002

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