8PZB
 
 | | crystal structure of VDR in complex with D-Bishomo-1a,25-dihydroxyvitamin D3 Analog 49 | | Descriptor: | (1~{R},3~{S},5~{Z})-5-[(2~{E})-2-[(4~{a}~{R},5~{S},9~{a}~{S})-4~{a}-methyl-5-[(2~{R})-6-methyl-6-oxidanyl-heptan-2-yl]-3,4,5,6,7,8,9,9~{a}-octahydro-2~{H}-benzo[7]annulen-1-ylidene]ethylidene]-4-methylidene-cyclohexane-1,3-diol, Nuclear receptor coactivator 2, Vitamin D3 receptor A | | Authors: | Rochel, N. | | Deposit date: | 2023-07-27 | | Release date: | 2024-04-24 | | Last modified: | 2024-05-22 | | Method: | X-RAY DIFFRACTION (2.73 Å) | | Cite: | Design, synthesis, and biological activity of D-bishomo-1 alpha ,25-dihydroxyvitamin D 3 analogs and their crystal structures with the vitamin D nuclear receptor.
Eur.J.Med.Chem., 271, 2024
|
|
8PNP
 | |
8QAE
 | | X-ray crystal structure of a de novo designed single-chain antiparallel 6-helix alpha-helical barrel, sc-apCC-6-SLLA | | Descriptor: | 2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-(2-hydroxyethyloxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanol, PENTAETHYLENE GLYCOL, sc-apCC-6-SLLA | | Authors: | Albanese, K.I, Petrenas, R, Woolfson, D.N. | | Deposit date: | 2023-08-22 | | Release date: | 2024-07-03 | | Last modified: | 2024-08-07 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Rationally seeded computational protein design of ɑ-helical barrels.
Nat.Chem.Biol., 20, 2024
|
|
8QAG
 | | X-ray crystal structure of a de novo designed single-chain parallel coiled-coil alpha-helical barrel with 6 inner helices, sc-CC-6-95 | | Descriptor: | DI(HYDROXYETHYL)ETHER, TETRAETHYLENE GLYCOL, sc-CC-6-95 | | Authors: | Petrenas, R, Albanese, K.I, Woolfson, D.N. | | Deposit date: | 2023-08-22 | | Release date: | 2024-07-03 | | Last modified: | 2024-08-07 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Rationally seeded computational protein design of ɑ-helical barrels.
Nat.Chem.Biol., 20, 2024
|
|
8PSH
 | | HIGH RESOLUTION NMR STRUCTURE OF THE STEREOREGULAR (ALL-RP)-PHOSPHOROTHIOATE-DNA/RNA HYBRID D (G*PS*C*PS*G*PS*T*PS*C*PS*A*PS*G*PS*G)R(CCUGACGC), MINIMIZED AVERAGE STRUCTURE | | Descriptor: | DNA (5'-D(*DGP*(SC)P*(GS)P*(PST)P*(SC)P*(AS)P*(GS)P*(GS))-3'), RNA (5'-R(*CP*CP*UP*GP*AP*CP*GP*C)-3') | | Authors: | Bachelin, M, Hessler, G, Kurz, G, Hacia, J.G, Dervan, P.B, Kessler, H. | | Deposit date: | 1997-10-13 | | Release date: | 1998-05-27 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Structure of a Stereoregular Phosphorothioate DNA/RNA Duplex
Nat.Struct.Biol., 5, 1998
|
|
8PRN
 | | E1M, K50A, R52A, D97A, E99A MUTANT OF RH. BLASTICA PORIN | | Descriptor: | (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, PORIN | | Authors: | Maveyraud, L, Schmid, B, Schulz, G.E. | | Deposit date: | 1998-06-12 | | Release date: | 1998-08-12 | | Last modified: | 2024-05-22 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Porin mutants with new channel properties.
Protein Sci., 7, 1998
|
|
7D77
 | | Cryo-EM structure of the cortisol-bound adhesion receptor GPR97-Go complex | | Descriptor: | (11alpha,14beta)-11,17,21-trihydroxypregn-4-ene-3,20-dione, Adhesion G protein-coupled receptor G3; GPR97, CHOLESTEROL, ... | | Authors: | Ping, Y, Mao, C, Xiao, P, Zhao, R, Jiang, Y, Yang, Z, An, W, Shen, D, Yang, F, Zhang, H, Qu, C, Shen, Q, Tian, C, Li, Z, Li, S, Wang, G, Tao, X, Wen, X, Zhong, Y, Yang, J, Yi, F, Yu, X, Xu, E, Zhang, Y, Sun, J. | | Deposit date: | 2020-10-03 | | Release date: | 2021-02-03 | | Last modified: | 2021-02-10 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Structures of the glucocorticoid-bound adhesion receptor GPR97-G o complex.
Nature, 589, 2021
|
|
8PKH
 | | Borrelia bacteriophage BB1 procapsid, fivefold-symmetrized outer shell | | Descriptor: | Decorator protein P03, Decorator protein P04, Decorator protein P05, ... | | Authors: | Rumnieks, J, Fuzik, T, Tars, K. | | Deposit date: | 2023-06-26 | | Release date: | 2023-07-12 | | Last modified: | 2023-11-15 | | Method: | ELECTRON MICROSCOPY (3.35 Å) | | Cite: | Structure of the Borrelia Bacteriophage phi BB1 Procapsid.
J.Mol.Biol., 435, 2023
|
|
8PII
 | | VHH Z70 mutant 3 in interaction with PHF6 Tau peptide | | Descriptor: | Microtubule-associated protein tau, VHH Z70 Mutant 3 | | Authors: | Dupre, E, Mortelecque, J, NGuyen, M, Hanoulle, X, Landrieu, I. | | Deposit date: | 2023-06-21 | | Release date: | 2023-07-05 | | Last modified: | 2024-04-24 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | A selection and optimization strategy for single-domain antibodies targeting the PHF6 linear peptide within the tau intrinsically disordered protein.
J.Biol.Chem., 300, 2024
|
|
7SPT
 | | Crystal structure of exofacial state human glucose transporter GLUT3 | | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Solute carrier family 2, facilitated glucose transporter member 3, ... | | Authors: | Wang, N, Jiang, X, Yan, N. | | Deposit date: | 2021-11-03 | | Release date: | 2022-05-18 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Molecular basis for inhibiting human glucose transporters by exofacial inhibitors.
Nat Commun, 13, 2022
|
|
8PHQ
 | | Top cap of the Borrelia bacteriophage BB1 procapsid, fivefold-symmetrized outer shell | | Descriptor: | Decorator protein P03, Decorator protein P05, Major capsid protein, ... | | Authors: | Rumnieks, J, Fuzik, T, Tars, K. | | Deposit date: | 2023-06-20 | | Release date: | 2023-07-19 | | Last modified: | 2023-11-15 | | Method: | ELECTRON MICROSCOPY (2.69 Å) | | Cite: | Structure of the Borrelia Bacteriophage phi BB1 Procapsid.
J.Mol.Biol., 435, 2023
|
|
4WMX
 | | The structure of MBP-MCL1 bound to ligand 6 at 2.0A | | Descriptor: | 4-ethenyl-2-[(phenylsulfonyl)amino]benzoic acid, FORMIC ACID, MAGNESIUM ION, ... | | Authors: | Clifton, M.C, Dranow, D.M. | | Deposit date: | 2014-10-09 | | Release date: | 2015-05-06 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | A Maltose-Binding Protein Fusion Construct Yields a Robust Crystallography Platform for MCL1.
Plos One, 10, 2015
|
|
8PHS
 | | Bottom cap of the Borrelia bacteriophage BB1 procapsid, fivefold-symmetrized outer shell | | Descriptor: | Decorator protein P03, Decorator protein P04, Decorator protein P05, ... | | Authors: | Rumnieks, J, Fuzik, T, Tars, K. | | Deposit date: | 2023-06-20 | | Release date: | 2023-07-19 | | Last modified: | 2023-11-15 | | Method: | ELECTRON MICROSCOPY (2.82 Å) | | Cite: | Structure of the Borrelia Bacteriophage phi BB1 Procapsid.
J.Mol.Biol., 435, 2023
|
|
8PHR
 | | Middle part of the Borrelia bacteriophage BB1 procapsid, tenfold-symmetrized outer shell | | Descriptor: | Decorator protein P03, Decorator protein P05, Major capsid protein, ... | | Authors: | Rumnieks, J, Fuzik, T, Tars, K. | | Deposit date: | 2023-06-20 | | Release date: | 2023-07-19 | | Last modified: | 2023-11-15 | | Method: | ELECTRON MICROSCOPY (2.65 Å) | | Cite: | Structure of the Borrelia Bacteriophage phi BB1 Procapsid.
J.Mol.Biol., 435, 2023
|
|
6Y68
 | |
8PHU
 | | Asymmetric structure of the portal-containing cap of the Borrelia bacteriophage BB1 procapsid | | Descriptor: | Decorator protein P03, Decorator protein P04, Decorator protein P05, ... | | Authors: | Rumnieks, J, Fuzik, T, Tars, K. | | Deposit date: | 2023-06-20 | | Release date: | 2023-07-19 | | Last modified: | 2023-11-15 | | Method: | ELECTRON MICROSCOPY (7.41 Å) | | Cite: | Structure of the Borrelia Bacteriophage phi BB1 Procapsid.
J.Mol.Biol., 435, 2023
|
|
4WMV
 | | STRUCTURE OF MBP-MCL1 BOUND TO ligand 4 AT 2.4A | | Descriptor: | 3-chloro-6-fluoro-1-benzothiophene-2-carboxylic acid, CHLORIDE ION, MAGNESIUM ION, ... | | Authors: | Clifton, M.C, Moulin, A. | | Deposit date: | 2014-10-09 | | Release date: | 2015-05-06 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | A Maltose-Binding Protein Fusion Construct Yields a Robust Crystallography Platform for MCL1.
Plos One, 10, 2015
|
|
8PFE
 | |
8POP
 | | HK97 small terminase in complex with DNA | | Descriptor: | DNA (31-MER), Terminase small subunit | | Authors: | Chechik, M, Greive, S.J, Antson, A.A, Jenkins, H.T. | | Deposit date: | 2023-07-05 | | Release date: | 2023-08-09 | | Last modified: | 2024-08-21 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Structural basis for DNA recognition by a viral genome-packaging machine.
Proc.Natl.Acad.Sci.USA, 121, 2024
|
|
7AQ1
 | | Crystal structure of human mature meprin beta in complex with the specific inhibitor MWT-S-270 | | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Linnert, M, Parthier, C, Fritz, C. | | Deposit date: | 2020-10-20 | | Release date: | 2021-03-03 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (2.413 Å) | | Cite: | Structure and Dynamics of Meprin beta in Complex with a Hydroxamate-Based Inhibitor.
Int J Mol Sci, 22, 2021
|
|
8PU7
 | | Structure of immature HTLV-1 CA-NTD from in vitro assembled MA126-CANC tubes: axis angle -20 degrees | | Descriptor: | Gag protein (Fragment) | | Authors: | Obr, M, Percipalle, M, Chernikova, D, Yang, H, Thader, A, Pinke, G, Porley, D, Mansky, L.M, Dick, R.A, Schur, F.K.M. | | Deposit date: | 2023-07-17 | | Release date: | 2023-08-23 | | Method: | ELECTRON MICROSCOPY (4.8 Å) | | Cite: | Unconventional stabilization of the human T-cell leukemia virus type 1 immature Gag lattice.
Biorxiv, 2023
|
|
8FHD
 | | Cryo-EM structure of human voltage-gated sodium channel Nav1.6 | | Descriptor: | (3beta,14beta,17beta,25R)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-en, (5E,17R,20S)-23-amino-20-hydroxy-14,20-dioxo-15,19,21-trioxa-20lambda~5~-phosphatricos-5-en-17-yl hexadecanoate, 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, ... | | Authors: | Fan, X, Huang, J, Yan, N. | | Deposit date: | 2022-12-14 | | Release date: | 2023-02-08 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Cryo-EM structure of human voltage-gated sodium channel Na v 1.6.
Proc.Natl.Acad.Sci.USA, 120, 2023
|
|
6YA0
 | | Crystal structure of TSWV glycoprotein N ectodomain (Trypsin treated) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, AMMONIUM ION, ... | | Authors: | Dessau, M, Bahat, Y. | | Deposit date: | 2020-03-11 | | Release date: | 2020-09-30 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (2.86 Å) | | Cite: | Crystal structure of tomato spotted wilt virus G N reveals a dimer complex formation and evolutionary link to animal-infecting viruses
Proc.Natl.Acad.Sci.USA, 117, 2020
|
|
8PU8
 | | Structure of immature HTLV-1 CA-NTD from in vitro assembled MA126-CANC tubes: axis angle -15 degrees | | Descriptor: | Gag protein (Fragment) | | Authors: | Obr, M, Percipalle, M, Chernikova, D, Yang, H, Thader, A, Pinke, G, Porley, D, Mansky, L.M, Dick, R.A, Schur, F.K.M. | | Deposit date: | 2023-07-17 | | Release date: | 2023-08-23 | | Method: | ELECTRON MICROSCOPY (4 Å) | | Cite: | Unconventional stabilization of the human T-cell leukemia virus type 1 immature Gag lattice.
Biorxiv, 2023
|
|
8Q2M
 | |
