8WJN
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![BU of 8wjn by Molmil](/molmil-images/mine/8wjn) | Cryo-EM structure of 6-subunit Smc5/6 head region | Descriptor: | Non-structural maintenance of chromosome element 3, Non-structural maintenance of chromosomes element 1, Non-structural maintenance of chromosomes element 4, ... | Authors: | Li, Q, Zhang, J, Zhang, X, Cheng, T, Wang, Z, Jin, D, Chen, Z, Wang, L. | Deposit date: | 2023-09-26 | Release date: | 2024-06-26 | Method: | ELECTRON MICROSCOPY (5.58 Å) | Cite: | Cryo-EM structures of Smc5/6 in multiple states reveal its assembly and functional mechanisms. Nat.Struct.Mol.Biol., 2024
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5YK7
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![BU of 5yk7 by Molmil](/molmil-images/mine/5yk7) | Crystal Structure of Mdm12-Mmm1 complex | Descriptor: | Maintenance of mitochondrial morphology protein 1, Mitochondrial distribution and morphology protein 12, PHOSPHATE ION | Authors: | Jeong, H, Park, J, Lee, C. | Deposit date: | 2017-10-12 | Release date: | 2018-01-10 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.799 Å) | Cite: | Crystal structures of Mmm1 and Mdm12-Mmm1 reveal mechanistic insight into phospholipid trafficking at ER-mitochondria contact sites. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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8WJO
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![BU of 8wjo by Molmil](/molmil-images/mine/8wjo) | Cryo-EM structure of 8-subunit Smc5/6 arm region | Descriptor: | DNA repair protein KRE29, E3 SUMO-protein ligase MMS21, Structural maintenance of chromosomes protein 5, ... | Authors: | Li, Q, Zhang, J, Zhang, X, Cheng, T, Wang, Z, Jin, D, Chen, Z, Wang, L. | Deposit date: | 2023-09-26 | Release date: | 2024-06-26 | Method: | ELECTRON MICROSCOPY (6.04 Å) | Cite: | Cryo-EM structures of Smc5/6 in multiple states reveal its assembly and functional mechanisms. Nat.Struct.Mol.Biol., 2024
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6K1D
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![BU of 6k1d by Molmil](/molmil-images/mine/6k1d) | Crystal structure of EXD2 exonuclease domain soaked in Mn and GMP | Descriptor: | Exonuclease 3'-5' domain-containing protein 2, MANGANESE (II) ION | Authors: | Park, J, Lee, C. | Deposit date: | 2019-05-10 | Release date: | 2019-05-22 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | The structure of human EXD2 reveals a chimeric 3' to 5' exonuclease domain that discriminates substrates via metal coordination. Nucleic Acids Res., 47, 2019
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6K1C
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![BU of 6k1c by Molmil](/molmil-images/mine/6k1c) | Crystal structure of EXD2 exonuclease domain soaked in Mg and dGMP | Descriptor: | Exonuclease 3'-5' domain-containing protein 2, MAGNESIUM ION | Authors: | Park, J, Lee, C. | Deposit date: | 2019-05-10 | Release date: | 2019-05-22 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | The structure of human EXD2 reveals a chimeric 3' to 5' exonuclease domain that discriminates substrates via metal coordination. Nucleic Acids Res., 47, 2019
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6K18
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![BU of 6k18 by Molmil](/molmil-images/mine/6k18) | Crystal structure of EXD2 exonuclease domain soaked in Mn | Descriptor: | Exonuclease 3'-5' domain-containing protein 2, MANGANESE (II) ION | Authors: | Park, J, Lee, C. | Deposit date: | 2019-05-10 | Release date: | 2019-05-22 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.303 Å) | Cite: | The structure of human EXD2 reveals a chimeric 3' to 5' exonuclease domain that discriminates substrates via metal coordination. Nucleic Acids Res., 47, 2019
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6K1A
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![BU of 6k1a by Molmil](/molmil-images/mine/6k1a) | Crystal structure of EXD2 exonuclease domain soaked in Mn and Mg | Descriptor: | Exonuclease 3'-5' domain-containing protein 2, MAGNESIUM ION, MANGANESE (II) ION | Authors: | Park, J, Lee, C. | Deposit date: | 2019-05-10 | Release date: | 2019-05-22 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.602 Å) | Cite: | The structure of human EXD2 reveals a chimeric 3' to 5' exonuclease domain that discriminates substrates via metal coordination. Nucleic Acids Res., 47, 2019
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6K19
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![BU of 6k19 by Molmil](/molmil-images/mine/6k19) | Crystal structure of EXD2 exonuclease domain soaked in Mg | Descriptor: | Exonuclease 3'-5' domain-containing protein 2, MAGNESIUM ION | Authors: | Park, J, Lee, C. | Deposit date: | 2019-05-10 | Release date: | 2019-05-22 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.202 Å) | Cite: | The structure of human EXD2 reveals a chimeric 3' to 5' exonuclease domain that discriminates substrates via metal coordination. Nucleic Acids Res., 47, 2019
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6K17
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![BU of 6k17 by Molmil](/molmil-images/mine/6k17) | Crystal structure of EXD2 exonuclease domain | Descriptor: | Exonuclease 3'-5' domain-containing protein 2, SODIUM ION | Authors: | Park, J, Lee, C. | Deposit date: | 2019-05-10 | Release date: | 2019-05-22 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.602 Å) | Cite: | The structure of human EXD2 reveals a chimeric 3' to 5' exonuclease domain that discriminates substrates via metal coordination. Nucleic Acids Res., 47, 2019
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6K1E
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![BU of 6k1e by Molmil](/molmil-images/mine/6k1e) | Crystal structure of EXD2 exonuclease domain soaked in Mg and GMP | Descriptor: | Exonuclease 3'-5' domain-containing protein 2, MAGNESIUM ION | Authors: | Park, J, Lee, C. | Deposit date: | 2019-05-10 | Release date: | 2019-05-22 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | The structure of human EXD2 reveals a chimeric 3' to 5' exonuclease domain that discriminates substrates via metal coordination. Nucleic Acids Res., 47, 2019
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6K1B
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![BU of 6k1b by Molmil](/molmil-images/mine/6k1b) | Crystal structure of EXD2 exonuclease domain soaked in Mn and dGMP | Descriptor: | Exonuclease 3'-5' domain-containing protein 2, MANGANESE (II) ION | Authors: | Park, J, Lee, C. | Deposit date: | 2019-05-10 | Release date: | 2019-05-22 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.605 Å) | Cite: | The structure of human EXD2 reveals a chimeric 3' to 5' exonuclease domain that discriminates substrates via metal coordination. Nucleic Acids Res., 47, 2019
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7X15
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![BU of 7x15 by Molmil](/molmil-images/mine/7x15) | Crystal structure of MIGA2 LD targeting domain | Descriptor: | DI-PALMITOYL-3-SN-PHOSPHATIDYLETHANOLAMINE, FORMIC ACID, Mitoguardin 2 | Authors: | Kim, H, Lee, C. | Deposit date: | 2022-02-23 | Release date: | 2022-09-14 | Method: | X-RAY DIFFRACTION (2.852 Å) | Cite: | Structural basis for mitoguardin-2 mediated lipid transport at ER-mitochondrial membrane contact sites. Nat Commun, 13, 2022
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7X14
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![BU of 7x14 by Molmil](/molmil-images/mine/7x14) | Crystal structure of phospho-FFAT motif of MIGA2 bound to VAPB | Descriptor: | MIGA2 phospho FFAT motif, SULFATE ION, Vesicle-associated membrane protein-associated protein B | Authors: | Kim, H, Lee, C. | Deposit date: | 2022-02-23 | Release date: | 2022-09-14 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.675 Å) | Cite: | Structural basis for mitoguardin-2 mediated lipid transport at ER-mitochondrial membrane contact sites. Nat Commun, 13, 2022
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6I0B
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![BU of 6i0b by Molmil](/molmil-images/mine/6i0b) | Human butyrylcholinesterase in complex with the S enantiomer of a chlorotacrine-tryptophan multi-target inhibitor. | Descriptor: | (2~{S})-2-azanyl-~{N}-[6-[(6-chloranyl-1,2,3,4-tetrahydroacridin-9-yl)amino]hexyl]-3-(1~{H}-indol-3-yl)propanamide, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Brazzolotto, X, Nachon, F. | Deposit date: | 2018-10-25 | Release date: | 2019-03-27 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.384 Å) | Cite: | Novel tacrine-tryptophan hybrids: Multi-target directed ligands as potential treatment for Alzheimer's disease. Eur.J.Med.Chem., 168, 2019
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6I0C
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![BU of 6i0c by Molmil](/molmil-images/mine/6i0c) | Human butyrylcholinesterase in complex with the R enantiomer of a chlorotacrine-tryptophan multi-target inhibitor. | Descriptor: | (2~{R})-2-azanyl-~{N}-[6-[(6-chloranyl-1,2,3,4-tetrahydroacridin-9-yl)amino]hexyl]-3-(1~{H}-indol-3-yl)propanamide, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Brazzolotto, X, Nachon, F. | Deposit date: | 2018-10-25 | Release date: | 2019-03-27 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.675 Å) | Cite: | Novel tacrine-tryptophan hybrids: Multi-target directed ligands as potential treatment for Alzheimer's disease. Eur.J.Med.Chem., 168, 2019
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8GW7
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![BU of 8gw7 by Molmil](/molmil-images/mine/8gw7) | AtSLAC1 6D mutant in open state | Descriptor: | CHLORIDE ION, CHOLESTEROL HEMISUCCINATE, Guard cell S-type anion channel SLAC1,Green fluorescent protein (Fragment) | Authors: | Lee, Y, Lee, S. | Deposit date: | 2022-09-16 | Release date: | 2023-11-15 | Last modified: | 2023-11-29 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Cryo-EM structures of the plant anion channel SLAC1 from Arabidopsis thaliana suggest a combined activation model. Nat Commun, 14, 2023
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8GW6
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![BU of 8gw6 by Molmil](/molmil-images/mine/8gw6) | AtSLAC1 6D mutant in closed state | Descriptor: | CHLORIDE ION, CHOLESTEROL HEMISUCCINATE, Guard cell S-type anion channel SLAC1,Green fluorescent protein (Fragment) | Authors: | Lee, Y, Lee, S. | Deposit date: | 2022-09-16 | Release date: | 2023-11-15 | Last modified: | 2023-11-29 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Cryo-EM structures of the plant anion channel SLAC1 from Arabidopsis thaliana suggest a combined activation model. Nat Commun, 14, 2023
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7YCJ
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![BU of 7ycj by Molmil](/molmil-images/mine/7ycj) | |
3EIO
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![BU of 3eio by Molmil](/molmil-images/mine/3eio) | Crystal Structure Analysis of DPPIV Inhibitor | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4-({4-[(3R)-3-amino-4-(2,4,5-trifluorophenyl)butanoyl]-1,4-diazepan-1-yl}carbonyl)benzoic acid, ... | Authors: | Ahn, J.H, Lee, J.-O. | Deposit date: | 2008-09-17 | Release date: | 2008-11-04 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Synthesis and biological evaluation of homopiperazine derivatives with beta-aminoacyl group as dipeptidyl peptidase IV inhibitors Bioorg.Med.Chem.Lett., 18, 2008
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4LYI
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![BU of 4lyi by Molmil](/molmil-images/mine/4lyi) | Crystal Structure of apo-BRD4(1) | Descriptor: | 1,2-ETHANEDIOL, Bromodomain-containing protein 4, IODIDE ION, ... | Authors: | Wohlwend, D. | Deposit date: | 2013-07-31 | Release date: | 2014-01-15 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | 4-Acyl pyrroles: mimicking acetylated lysines in histone code reading. Angew.Chem.Int.Ed.Engl., 52, 2013
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1JY2
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![BU of 1jy2 by Molmil](/molmil-images/mine/1jy2) | Crystal Structure of the Central Region of Bovine Fibrinogen (E5 fragment) at 1.4 Angstroms Resolution | Descriptor: | FIBRINOGEN ALPHA CHAIN, FIBRINOGEN BETA CHAIN, FIBRINOGEN GAMMA-B CHAIN | Authors: | Madrazo, J, Brown, J.H, Litvinovich, S, Dominguez, R, Yakovlev, S, Medved, L, Cohen, C. | Deposit date: | 2001-09-10 | Release date: | 2001-10-17 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Crystal structure of the central region of bovine fibrinogen (E5 fragment) at 1.4-A resolution. Proc.Natl.Acad.Sci.USA, 98, 2001
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1JY3
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![BU of 1jy3 by Molmil](/molmil-images/mine/1jy3) | Crystal Structure of the Central Region of Bovine Fibrinogen (E5 Fragment) at 1.4 Angstroms Resolution | Descriptor: | FIBRINOGEN ALPHA CHAIN, FIBRINOGEN BETA CHAIN, FIBRINOGEN GAMMA-B CHAIN | Authors: | Madrazo, J, Brown, J.H, Litvinovich, S, Dominguez, R, Yakovlev, S, Medved, L, Cohen, C. | Deposit date: | 2001-09-10 | Release date: | 2001-10-17 | Last modified: | 2017-10-04 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Crystal structure of the central region of bovine fibrinogen (E5 fragment) at 1.4-A resolution. Proc.Natl.Acad.Sci.USA, 98, 2001
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1LGR
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![BU of 1lgr by Molmil](/molmil-images/mine/1lgr) | |
3CMJ
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![BU of 3cmj by Molmil](/molmil-images/mine/3cmj) | |
7YO8
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![BU of 7yo8 by Molmil](/molmil-images/mine/7yo8) | |