PDB: 5470 resultsInfo pagesStatus searchChemie searchBIRD

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6QU1	Crystal structure of the KAP1 RBCC domain in complex with the SMARCAD1 CUE1 domain at 3.7 angstrom resolution. Descriptor: SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1, Transcription intermediary factor 1-beta,Transcription intermediary factor 1-beta, ZINC ION Authors: Newman, J.A, Aitkenhead, H, Gavard, A, Lim, M, Williams, H.L, Svejstrup, J.Q, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O. Deposit date: 2019-02-26 Release date: 2019-07-17 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (3.7 Å) Cite: A Ubiquitin-Binding Domain that Binds a Structural Fold Distinct from that of Ubiquitin. Structure, 2019
1A3S	HUMAN UBC9 Descriptor: UBC9 Authors: Naismith, J.H, Giraud, M. Deposit date: 1998-01-23 Release date: 1998-05-27 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Structure of ubiquitin-conjugating enzyme 9 displays significant differences with other ubiquitin-conjugating enzymes which may reflect its specificity for sumo rather than ubiquitin. Acta Crystallogr.,Sect.D, 54, 1998
8OX0	Structure of apo telomeric nucleosome Descriptor: Histone H2A type 1-C, Histone H2B type 1-C/E/F/G/I, Histone H3.1, ... Authors: Hu, H, van Roon, A.M.M, Ghanim, G.E, Ahsan, B, Oluwole, A, Peak-Chew, S, Robinson, C.V, Nguyen, T.H.D. Deposit date: 2023-04-28 Release date: 2023-08-30 Last modified: 2023-09-06 Method: ELECTRON MICROSCOPY (2.52 Å) Cite: Structural basis of telomeric nucleosome recognition by shelterin factor TRF1. Sci Adv, 9, 2023
8P4C	Structural insights into human co-transcriptional capping - structure 3 Descriptor: DNA (32-MER), DNA (41-MER), DNA-directed RNA polymerase II subunit E, ... Authors: Garg, G, Dienemann, C, Farnung, L, Schwarz, J, Linden, A, Urlaub, H, Cramer, P. Deposit date: 2023-05-20 Release date: 2023-08-16 Method: ELECTRON MICROSCOPY (3.8 Å) Cite: Structural insights into human co-transcriptional capping. Mol.Cell, 83, 2023
8P4D	Structural insights into human co-transcriptional capping - structure 4 Descriptor: DNA (32-MER), DNA (41-MER), DNA-directed RNA polymerase II subunit E, ... Authors: Garg, G, Dienemann, C, Farnung, L, Schwarz, J, Linden, A, Urlaub, H, Cramer, P. Deposit date: 2023-05-20 Release date: 2023-08-16 Method: ELECTRON MICROSCOPY (3.6 Å) Cite: Structural insights into human co-transcriptional capping. Mol.Cell, 83, 2023
8ONS	TAF15 amyloid fold in atypical FTLD - Individual 1 Descriptor: TATA-binding protein-associated factor 2N Authors: Tetter, S, Ryskeldi-Falcon, B. Deposit date: 2023-04-03 Release date: 2023-12-06 Last modified: 2024-02-07 Method: ELECTRON MICROSCOPY (1.97 Å) Cite: TAF15 amyloid filaments in frontotemporal lobar degeneration. Nature, 625, 2024
8OUE	The H/ACA RNP lobe of human telomerase with the dyskerin thumb loop in a semi-closed conformation Descriptor: H/ACA ribonucleoprotein complex subunit 1, H/ACA ribonucleoprotein complex subunit 2, H/ACA ribonucleoprotein complex subunit 3, ... Authors: Ghanim, G.E, Sekne, Z, van Roon, A.M.M, Balch, S, Nguyen, T.H.D. Deposit date: 2023-04-22 Release date: 2024-01-31 Last modified: 2024-02-07 Method: ELECTRON MICROSCOPY (2.7 Å) Cite: 2.7 angstrom cryo-EM structure of human telomerase H/ACA ribonucleoprotein. Nat Commun, 15, 2024
8OUF	The H/ACA RNP lobe of human telomerase with the dyskerin thumb loop in an open conformation Descriptor: H/ACA ribonucleoprotein complex subunit 1, H/ACA ribonucleoprotein complex subunit 2, H/ACA ribonucleoprotein complex subunit 3, ... Authors: Ghanim, G.E, Sekne, Z, van Roon, A.M.M, Balch, S, Nguyen, T.H.D. Deposit date: 2023-04-22 Release date: 2024-01-31 Last modified: 2024-02-07 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: 2.7 angstrom cryo-EM structure of human telomerase H/ACA ribonucleoprotein. Nat Commun, 15, 2024
8P09	48S late-stage initiation complex with non methylated mRNA Descriptor: 18S ribosomal RNA, 40S ribosomal protein S11, 40S ribosomal protein S12, ... Authors: Guca, E, Lima, L.H.F, Boissier, F, Hashem, Y. Deposit date: 2023-05-09 Release date: 2024-03-20 Method: ELECTRON MICROSCOPY (3.3 Å) Cite: N 6 -methyladenosine in 5' UTR does not promote translation initiation. Mol.Cell, 84, 2024
8P03	48S late-stage initiation complex with m6A mRNA Descriptor: 18S ribosomal RNA, 40S ribosomal protein S11, 40S ribosomal protein S12, ... Authors: Guca, E, Lima, L.H.F, Boissier, F, Hashem, Y. Deposit date: 2023-05-09 Release date: 2024-03-20 Last modified: 2024-04-24 Method: ELECTRON MICROSCOPY (3.04 Å) Cite: N 6 -methyladenosine in 5' UTR does not promote translation initiation. Mol.Cell, 84, 2024
1L3K	UP1, THE TWO RNA-RECOGNITION MOTIF DOMAIN OF HNRNP A1 Descriptor: HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN A1 Authors: Vitali, J, Ding, J, Jiang, J, Zhang, Y, Krainer, A.R, Xu, R.-M. Deposit date: 2002-02-27 Release date: 2002-04-17 Last modified: 2023-08-16 Method: X-RAY DIFFRACTION (1.1 Å) Cite: Correlated alternative side chain conformations in the RNA-recognition motif of heterogeneous nuclear ribonucleoprotein A1. Nucleic Acids Res., 30, 2002
6H3A	Crystal structure of the KAP1 RBCC domain in complex with the SMARCAD1 CUE1 domain. Descriptor: SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1, Transcription intermediary factor 1-beta, ZINC ION Authors: Newman, J.A, Aitkenhead, H, Lim, M, Williams, H.L, Svejstrup, J.Q, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O. Deposit date: 2018-07-17 Release date: 2019-06-26 Last modified: 2024-05-15 Method: X-RAY DIFFRACTION (5.505 Å) Cite: A Ubiquitin-Binding Domain that Binds a Structural Fold Distinct from that of Ubiquitin. Structure, 27, 2019
7Q3L	Human 17S U2 snRNP 5' domain Descriptor: HIV Tat-specific factor 1, PHD finger-like domain-containing protein 5A, Probable ATP-dependent RNA helicase DDX46, ... Authors: Tholen, J, Galej, W.P. Deposit date: 2021-10-28 Release date: 2022-03-30 Last modified: 2024-07-17 Method: ELECTRON MICROSCOPY (2.21 Å) Cite: Structural basis of branch site recognition by the human spliceosome. Science, 375, 2022
7R5K	Human nuclear pore complex (constricted) Descriptor: Aladin, E3 SUMO-protein ligase RanBP2, Nuclear pore complex protein Nup107, ... Authors: Mosalaganti, S, Obarska-Kosinska, A, Siggel, M, Taniguchi, R, Turonova, B, Zimmerli, C.E, Buczak, K, Schmidt, F.H, Margiotta, E, Mackmull, M.T, Hagen, W.J.H, Hummer, G, Kosinski, J, Beck, M. Deposit date: 2022-02-10 Release date: 2022-06-22 Last modified: 2024-07-17 Method: ELECTRON MICROSCOPY (12 Å) Cite: AI-based structure prediction empowers integrative structural analysis of human nuclear pores. Science, 376, 2022
7R5J	Human nuclear pore complex (dilated) Descriptor: Aladin, E3 SUMO-protein ligase RanBP2, Nuclear pore complex protein Nup107, ... Authors: Mosalaganti, S, Obarska-Kosinska, A, Siggel, M, Taniguchi, R, Turonova, B, Zimmerli, C.E, Buczak, K, Schmidt, F.H, Margiotta, E, Mackmull, M.T, Hagen, W.J.H, Hummer, G, Kosinski, J, Beck, M. Deposit date: 2022-02-10 Release date: 2022-09-21 Last modified: 2024-07-17 Method: ELECTRON MICROSCOPY (50 Å) Cite: AI-based structure prediction empowers integrative structural analysis of human nuclear pores Science, 376, 2022
6JLB	Crystal structure of lamin A/C fragment and assembly mechanisms of intermediate filaments Descriptor: Lamin A/C Authors: Ahn, J, Jo, I, Ha, N.C. Deposit date: 2019-03-04 Release date: 2019-09-11 Method: X-RAY DIFFRACTION (3.205 Å) Cite: Structural basis for lamin assembly at the molecular level. Nat Commun, 10, 2019
1PGZ	Crystal Structure of UP1 Complexed With d(TTAGGGTTAG(6-MI)G); A Human Telomeric Repeat Containing 6-methyl-8-(2-deoxy-beta-ribofuranosyl)isoxanthopteridine (6-MI) Descriptor: 5'-D(*T*TP*AP*GP*GP*GP*TP*TP*AP*GP*(6MI)P*G)-3', Heterogeneous nuclear ribonucleoprotein A1 Authors: Myers, J.C, Moore, S.A, Shamoo, Y. Deposit date: 2003-05-28 Release date: 2003-11-11 Last modified: 2023-08-16 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Structure-based incorporation of 6-methyl-8-(2-deoxy-beta-ribofuranosyl)isoxanthopteridine into the human telomeric repeat DNA as a probe for UP1 binding and destabilization of G-tetrad structures J.Biol.Chem., 278, 2003
4M38	Crystal structure of Trypanosoma brucei protein arginine methyltransferase 7 complex with AdoHcy and histone H4 peptide Descriptor: Histone H4, Protein arginine N-methyltransferase 7, S-ADENOSYL-L-HOMOCYSTEINE Authors: Wang, C, Zhu, Y, Shi, Y. Deposit date: 2013-08-06 Release date: 2014-04-23 Last modified: 2024-05-29 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Structural determinants for the strict monomethylation activity by trypanosoma brucei protein arginine methyltransferase 7. Structure, 22, 2014
2KRR	Solution structure of the RBD1,2 domains from human nucleolin Descriptor: Nucleolin Authors: Arumugam, N, Miller, C, Maliekal, J, Bates, P.J, Trent, J.O, Lane, A.N. Deposit date: 2009-12-22 Release date: 2010-05-05 Last modified: 2024-05-08 Method: SOLUTION NMR Cite: Solution structure of the RBD1,2 domains from human nucleolin. J.Biomol.Nmr, 47, 2010
2N1V	Solution structure of human SUMO1 Descriptor: Small ubiquitin-related modifier 1 Authors: Naik, M.T, Naik, N, Shih, H, Huang, T. Deposit date: 2015-04-24 Release date: 2016-04-20 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: Structures of human SUMO To Be Published
7SYN	Structure of the HCV IRES bound to the 40S ribosomal subunit, head opening. Structure 8(delta dII) Descriptor: 18S rRNA, 40S ribosomal protein S2, HCV IRES, ... Authors: Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J. Deposit date: 2021-11-25 Release date: 2022-07-13 Method: ELECTRON MICROSCOPY (4 Å) Cite: Molecular architecture of 40S initiation complexes on the Hepatitis C virus IRES: from ribosomal attachment to eIF5B-mediated reorientation of initiator tRNA To Be Published
7SYG	Structure of the HCV IRES binding to the 40S ribosomal subunit, closed conformation. Structure 1(delta dII) Descriptor: 18S rRNA, 40S ribosomal protein S2, 40S ribosomal protein S24, ... Authors: Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J. Deposit date: 2021-11-25 Release date: 2022-07-13 Last modified: 2024-02-28 Method: ELECTRON MICROSCOPY (4.3 Å) Cite: Molecular architecture of 40S initiation complexes on the Hepatitis C virus IRES: from ribosomal attachment to eIF5B-mediated reorientation of initiator tRNA To Be Published
7SYM	Structure of the HCV IRES bound to the 40S ribosomal subunit, head opening. Structure 7(delta dII) Descriptor: 18S rRNA, 40S ribosomal protein S2, 40S ribosomal protein S21, ... Authors: Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J. Deposit date: 2021-11-25 Release date: 2022-07-13 Last modified: 2024-02-28 Method: ELECTRON MICROSCOPY (4.8 Å) Cite: Comprehensive structural overview of the HCV IRES-mediated translation initiation pathway To Be Published
7SYU	Structure of the delta dII IRES w/o eIF2 48S initiation complex, closed conformation. Structure 13(delta dII) Descriptor: 18S rRNA, 40S ribosomal protein S21, 40S ribosomal protein S24, ... Authors: Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J. Deposit date: 2021-11-25 Release date: 2022-07-13 Last modified: 2023-02-01 Method: ELECTRON MICROSCOPY (4.6 Å) Cite: Molecular architecture of 40S translation initiation complexes on the hepatitis C virus IRES. Embo J., 41, 2022
7SYT	Structure of the wt IRES w/o eIF2 48S initiation complex, closed conformation. Structure 13(wt) Descriptor: 18S rRNA, 40S ribosomal protein S21, 40S ribosomal protein S24, ... Authors: Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J. Deposit date: 2021-11-25 Release date: 2022-07-13 Last modified: 2023-02-01 Method: ELECTRON MICROSCOPY (4.4 Å) Cite: Molecular architecture of 40S translation initiation complexes on the hepatitis C virus IRES. Embo J., 41, 2022

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