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5B38
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BU of 5b38 by Molmil
KIR3DL1*005 in complex with HLA-B*57:01
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, HLA class I histocompatibility antigen, ...
Authors:Vivian, J.P, Rossjohn, J.
Deposit date:2016-02-12
Release date:2016-03-30
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Killer cell immunoglobulin-like receptor 3DL1 polymorphism defines distinct hierarchies of HLA class I recognition
J.Exp.Med., 213, 2016
3IMT
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BU of 3imt by Molmil
Transthyretin in complex with (E)-4-(4-aminostyryl)-2,6-dibromophenol
Descriptor: 4-[(E)-2-(4-aminophenyl)ethenyl]-2,6-dibromophenol, Transthyretin
Authors:Connelly, S, Wilson, I.
Deposit date:2009-08-11
Release date:2010-01-12
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:A substructure combination strategy to create potent and selective transthyretin kinetic stabilizers that prevent amyloidogenesis and cytotoxicity.
J.Am.Chem.Soc., 132, 2010
7N6E
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BU of 7n6e by Molmil
TCR peptide HLA-A2 complex
Descriptor: Beta-2-microglobulin, MHC class I antigen, Spike protein S1, ...
Authors:Chaurasia, P, Rossjohn, J, Petersen, J.
Deposit date:2021-06-08
Release date:2021-07-28
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural basis of biased T cell receptor recognition of an immunodominant HLA-A2 epitope of the SARS-CoV-2 spike protein.
J.Biol.Chem., 297, 2021
7N6D
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BU of 7n6d by Molmil
HLA peptide complex
Descriptor: 1,2-ETHANEDIOL, Beta-2-microglobulin, MHC class I antigen, ...
Authors:Chaurasia, P, Petersen, J, Rossjohn, J.
Deposit date:2021-06-08
Release date:2021-07-28
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis of biased T cell receptor recognition of an immunodominant HLA-A2 epitope of the SARS-CoV-2 spike protein.
J.Biol.Chem., 297, 2021
3IPV
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BU of 3ipv by Molmil
Crystal structure of Spatholobus parviflorus seed lectin
Descriptor: CALCIUM ION, Lectin alpha chain, Lectin beta chain, ...
Authors:Geethanandan, K, Bharath, S.R, Abhilash, J, Sadasivan, C, Haridas, M.
Deposit date:2009-08-18
Release date:2009-09-08
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.04 Å)
Cite:X-ray structure of a galactose-specific lectin from Spatholobous parviflorous
Int.J.Biol.Macromol., 49, 2011
6B5H
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BU of 6b5h by Molmil
ALDH1A2 liganded with NAD and 1-(4-cyanophenyl)-N-(3-fluorophenyl)-3-[4-(methylsulfonyl)phenyl]-1H-pyrazole-4-carboxamide (compound CM121)
Descriptor: 1-(4-cyanophenyl)-N-(3-fluorophenyl)-3-[4-(methylsulfonyl)phenyl]-1H-pyrazole-4-carboxamide, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Retinal dehydrogenase 2
Authors:Chen, Y, Zhu, J.-Y, Schonbrunn, E.
Deposit date:2017-09-29
Release date:2018-01-10
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural Basis of ALDH1A2 Inhibition by Irreversible and Reversible Small Molecule Inhibitors.
ACS Chem. Biol., 13, 2018
5XZI
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BU of 5xzi by Molmil
Crystal structure of the Zn-directed tetramer of the engineered cyt cb562 variant, AB5
Descriptor: CHLORIDE ION, HEME C, Soluble cytochrome b562, ...
Authors:Song, W.J, Tezcan, F.A.
Deposit date:2017-07-12
Release date:2017-12-20
Last modified:2019-10-02
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Importance of Scaffold Flexibility/Rigidity in the Design and Directed Evolution of Artificial Metallo-beta-lactamases.
J. Am. Chem. Soc., 139, 2017
3IMU
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BU of 3imu by Molmil
Transthyretin in complex with (E)-4-(3-aminostyryl)-2,6-dibromoaniline
Descriptor: 4-[(E)-2-(3-aminophenyl)ethenyl]-2,6-dibromoaniline, Transthyretin
Authors:Connelly, S, Wilson, I.A.
Deposit date:2009-08-11
Release date:2010-01-12
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:A substructure combination strategy to create potent and selective transthyretin kinetic stabilizers that prevent amyloidogenesis and cytotoxicity.
J.Am.Chem.Soc., 132, 2010
5TN2
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BU of 5tn2 by Molmil
Solution Structure of the C-terminal multimerization domain of the master biofilm-regulator SinR from Bacillus subtilis
Descriptor: HTH-type transcriptional regulator SinR
Authors:Draughn, G.L, Bobay, B.G, Stowe, S.D, Thompson, R.J, Cavanagh, J.
Deposit date:2016-10-13
Release date:2017-10-25
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:The Solution Structures and Interaction of SinR and SinI: Elucidating the Mechanism of Action of the Master Regulator Switch for Biofilm Formation in Bacillus subtilis.
J.Mol.Biol., 2019
3IGK
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BU of 3igk by Molmil
Diversity in DNA recognition by p53 revealed by crystal structures with Hoogsteen base pairs (p53-DNA complex 2)
Descriptor: Cellular tumor antigen p53, DNA (5'-D(*CP*GP*GP*GP*CP*AP*TP*GP*CP*CP*CP*G)-3'), ZINC ION
Authors:Suad, O, Rabinovich, D, Rozenberg, H, Shakked, Z.
Deposit date:2009-07-28
Release date:2010-03-31
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Diversity in DNA recognition by p53 revealed by crystal structures with Hoogsteen base pairs
Nat.Struct.Mol.Biol., 17, 2010
6B5G
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BU of 6b5g by Molmil
ALDH1A2 liganded with NAD and (3-ethoxythiophen-2-yl){4-[4-nitro-3-(pyrrolidin-1-yl)phenyl]piperazin-1-yl}methanone (compound 6-118)
Descriptor: (3-ethoxythiophen-2-yl){4-[4-nitro-3-(pyrrolidin-1-yl)phenyl]piperazin-1-yl}methanone, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Retinal dehydrogenase 2
Authors:Chen, Y, Zhu, J.-Y, Schonbrunn, E.
Deposit date:2017-09-29
Release date:2018-01-10
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural Basis of ALDH1A2 Inhibition by Irreversible and Reversible Small Molecule Inhibitors.
ACS Chem. Biol., 13, 2018
6AYV
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BU of 6ayv by Molmil
Crystal structure of fructose-1,6-bisphosphatase T84A from Mycobacterium tuberculosis
Descriptor: 6-O-phosphono-beta-D-fructofuranose, Fructose-1,6-bisphosphatase class 2, GLYCEROL, ...
Authors:Abad-Zapatero, C, Wolf, N, Gutka, H.J, Movahedzadeh, F.
Deposit date:2017-09-08
Release date:2018-03-14
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structures of the Mycobacterium tuberculosis GlpX protein (class II fructose-1,6-bisphosphatase): implications for the active oligomeric state, catalytic mechanism and citrate inhibition.
Acta Crystallogr D Struct Biol, 74, 2018
3ITW
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BU of 3itw by Molmil
Crystal structure of TioX from Micromonospora sp. ML1
Descriptor: Protein tioX
Authors:Biswas, T, Garneau-Tsodikova, S, Tsodikov, O.V.
Deposit date:2009-08-28
Release date:2010-02-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:A New Scaffold of an Old Protein Fold Ensures Binding to the Bisintercalator Thiocoraline.
J.Mol.Biol., 397, 2010
5C6V
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BU of 5c6v by Molmil
Crystal structure of the rice Topless related protein 2 (TPR2) N-terminal domain (1-209) in complex with Arabidopsis NINJA peptide
Descriptor: AFP homolog 2, ASPR2 protein
Authors:Ke, J, Ma, H, Gu, X, Brunzelle, J.S, Xu, H.E, Melcher, K.
Deposit date:2015-06-23
Release date:2015-08-05
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural basis for recognition of diverse transcriptional repressors by the TOPLESS family of corepressors.
Sci Adv, 1, 2015
5C7F
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BU of 5c7f by Molmil
Crystal structure of the rice Topless related protein 2 (TPR2) N-terminal domain (1-209) in complex with Arabidopsis IAA1 peptide
Descriptor: ASPR2 protein, Auxin-responsive protein IAA1, ZINC ION
Authors:Ke, J, Ma, H, Gu, X, Brunzelle, J.S, Xu, H.E, Melcher, K.
Deposit date:2015-06-24
Release date:2015-08-05
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural basis for recognition of diverse transcriptional repressors by the TOPLESS family of corepressors.
Sci Adv, 1, 2015
6B5I
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BU of 6b5i by Molmil
ALDH1A2 liganded with 1-(4-cyanophenyl)-N-(3-fluorophenyl)-3-[4-(methylsulfonyl)phenyl]-1H-pyrazole-4-carboxamide (compound CM121)
Descriptor: 1-(4-cyanophenyl)-N-(3-fluorophenyl)-3-[4-(methylsulfonyl)phenyl]-1H-pyrazole-4-carboxamide, Retinal dehydrogenase 2
Authors:Chen, Y, Zhu, J.-Y, Schonbrunn, E.
Deposit date:2017-09-29
Release date:2018-01-10
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural Basis of ALDH1A2 Inhibition by Irreversible and Reversible Small Molecule Inhibitors.
ACS Chem. Biol., 13, 2018
3IGL
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BU of 3igl by Molmil
Diversity in DNA recognition by p53 revealed by crystal structures with Hoogsteen base pairs (p53-DNA complex 1)
Descriptor: 1,2-ETHANEDIOL, Cellular tumor antigen p53, DNA (5'-D(*CP*GP*GP*GP*CP*AP*TP*GP*CP*CP*CP*G)-3'), ...
Authors:Kitayner, M, Suad, O, Rozenberg, H, Shakked, Z.
Deposit date:2009-07-28
Release date:2010-03-31
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Diversity in DNA recognition by p53 revealed by crystal structures with Hoogsteen base pairs
Nat.Struct.Mol.Biol., 17, 2010
3IMV
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BU of 3imv by Molmil
Transthyretin in complex with (E)-4-(4-aminostyryl)-2,6-dibromoaniline
Descriptor: 4-[(E)-2-(4-aminophenyl)ethenyl]-2,6-dibromoaniline, Transthyretin
Authors:Connelly, S, Wilson, I.A.
Deposit date:2009-08-11
Release date:2010-01-12
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.47 Å)
Cite:A substructure combination strategy to create potent and selective transthyretin kinetic stabilizers that prevent amyloidogenesis and cytotoxicity.
J.Am.Chem.Soc., 132, 2010
5C8F
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BU of 5c8f by Molmil
Crystal structure of light-exposed full-length Thermus thermophilus CarH bound to cobalamin
Descriptor: CHLORIDE ION, COBALAMIN, GLYCEROL, ...
Authors:Jost, M, Drennan, C.L.
Deposit date:2015-06-25
Release date:2015-09-30
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Structural basis for gene regulation by a B12-dependent photoreceptor.
Nature, 526, 2015
3IXQ
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BU of 3ixq by Molmil
Structure of ribose 5-phosphate isomerase a from methanocaldococcus jannaschii
Descriptor: ACETATE ION, CHLORIDE ION, Ribose-5-phosphate isomerase A, ...
Authors:Antonyuk, S.V, Ellis, M.J, Strange, R.W, Hasnain, S.S, Bessho, Y, Kuramitsu, S, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2009-09-04
Release date:2009-10-06
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:The structure of an archaeal ribose-5-phosphate isomerase from Methanocaldococcus jannaschii (MJ1603).
Acta Crystallogr.,Sect.F, 65, 2009
7KJX
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BU of 7kjx by Molmil
Structure of HIV-1 reverse transcriptase initiation complex core with nevirapine
Descriptor: 11-CYCLOPROPYL-5,11-DIHYDRO-4-METHYL-6H-DIPYRIDO[3,2-B:2',3'-E][1,4]DIAZEPIN-6-ONE, HIV-1 viral RNA fragment, MAGNESIUM ION, ...
Authors:Ha, B, Larsen, K.P, Zhang, J, Fu, Z, Montabana, E, Jackson, L.N, Chen, D.H, Puglisi, E.V.
Deposit date:2020-10-26
Release date:2021-03-17
Last modified:2021-05-12
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:High-resolution view of HIV-1 reverse transcriptase initiation complexes and inhibition by NNRTI drugs.
Nat Commun, 12, 2021
7KJV
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BU of 7kjv by Molmil
Structure of HIV-1 reverse transcriptase initiation complex core
Descriptor: HIV-1 viral RNA fragment, MAGNESIUM ION, Reverse transcriptase/ribonuclease H, ...
Authors:Ha, B, Larsen, K.P, Zhang, J, Fu, Z, Montabana, E, Jackson, L.N, Chen, D.H, Puglisi, E.V.
Deposit date:2020-10-26
Release date:2021-03-17
Last modified:2021-05-12
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:High-resolution view of HIV-1 reverse transcriptase initiation complexes and inhibition by NNRTI drugs.
Nat Commun, 12, 2021
7KJW
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BU of 7kjw by Molmil
Structure of HIV-1 reverse transcriptase initiation complex core with efavirenz
Descriptor: (-)-6-CHLORO-4-CYCLOPROPYLETHYNYL-4-TRIFLUOROMETHYL-1,4-DIHYDRO-2H-3,1-BENZOXAZIN-2-ONE, HIV-1 viral RNA fragment, MAGNESIUM ION, ...
Authors:Ha, B, Larsen, K.P, Zhang, J, Fu, Z, Montabana, E, Jackson, L.N, Chen, D.H, Puglisi, E.V.
Deposit date:2020-10-26
Release date:2021-03-17
Last modified:2021-05-12
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:High-resolution view of HIV-1 reverse transcriptase initiation complexes and inhibition by NNRTI drugs.
Nat Commun, 12, 2021
5XZJ
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BU of 5xzj by Molmil
Crystal structure of the Zn-directed tetramer of the engineered cyt cb562 variant, C96T/AB5
Descriptor: CHLORIDE ION, HEME C, Soluble cytochrome b562, ...
Authors:Song, W.J, Tezcan, F.A.
Deposit date:2017-07-12
Release date:2017-12-20
Last modified:2022-03-23
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Importance of Scaffold Flexibility/Rigidity in the Design and Directed Evolution of Artificial Metallo-beta-lactamases.
J. Am. Chem. Soc., 139, 2017
3WLV
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BU of 3wlv by Molmil
Thermostable urate oxidase from Bacillus sp. TB-90
Descriptor: 8-AZAXANTHINE, CHLORIDE ION, POTASSIUM ION, ...
Authors:Hibi, T, Hayashi, Y, Itoh, T.
Deposit date:2013-11-14
Release date:2014-06-18
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (1.747 Å)
Cite:Intersubunit salt bridges with a sulfate anion control subunit dissociation and thermal stabilization of Bacillus sp. TB-90 urate oxidase.
Biochemistry, 53, 2014

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數據於2024-07-17公開中

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