PDB: 45953 resultsInfo pagesStatus searchChemie searchBIRD

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7ENC	TFIID-based PIC-Mediator holo-complex in fully-assembled state (hPIC-MED) Descriptor: CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ... Authors: Chen, X, Qi, Y, Wang, X, Wu, Z, Yin, X, Li, J, Liu, W, Xu, Y. Deposit date: 2021-04-16 Release date: 2021-05-26 Last modified: 2021-06-16 Method: ELECTRON MICROSCOPY (4.13 Å) Cite: Structures of the human Mediator and Mediator-bound preinitiation complex. Science, 372, 2021
5SVA	Mediator-RNA Polymerase II Pre-Initiation Complex Descriptor: 108bp HIS4 Promoter Non-template Strand (-92/+16), 108bp HIS4 Promoter Template Strand (+16/-92), DNA repair helicase RAD25, ... Authors: Robinson, P.J, Bushnell, D.A, Kornberg, R.D. Deposit date: 2016-08-05 Release date: 2016-09-28 Last modified: 2019-11-27 Method: ELECTRON MICROSCOPY (15.3 Å) Cite: Structure of a Complete Mediator-RNA Polymerase II Pre-Initiation Complex. Cell, 166, 2016
7UBM	Transcription antitermination complex: "pre-engaged" Qlambda-loading complex Descriptor: Antitermination protein Q, DNA (52-MER), DNA (53-MER), ... Authors: Yin, Z, Ebright, R.H. Deposit date: 2022-03-15 Release date: 2022-09-28 Last modified: 2024-06-12 Method: ELECTRON MICROSCOPY (3.13 Å) Cite: In transcription antitermination by Q lambda , NusA induces refolding of Q lambda to form a nozzle that extends the RNA polymerase RNA-exit channel. Proc.Natl.Acad.Sci.USA, 119, 2022
4UIG	Structure of the copper sensitive operon repressor from Streptomyces lividans at pH6 Descriptor: COPPER SENSITIVE OPERON REPRESSOR, SULFATE ION Authors: Porto, T, Hough, M.A, Worrall, J.A.R. Deposit date: 2015-03-30 Release date: 2015-09-09 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2 Å) Cite: Structural Insights Into Conformational Switching in the Copper Metalloregulator Csor from Streptomyces Lividans Acta Crystallogr.,Sect.D, 71, 2015
7DOG	Crystal structure of a nuclease and capping domain of SbcD from Staphylococcus aureus Descriptor: MANGANESE (II) ION, Nuclease SbcCD subunit D Authors: Lee, J, Ha, N.-C. Deposit date: 2020-12-14 Release date: 2021-05-05 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.91 Å) Cite: Crystal structure of the nuclease and capping domain of SbcD from Staphylococcus aureus. J.Microbiol, 59, 2021
7SZK	Cryo-EM structure of 27a bound to E. coli RNAP and rrnBP1 promoter complex Descriptor: (2S,7R,7aR,13aP,16Z,18E,20S,21S,22R,23R,24R,25S,26R,27S,28E)-5,21,23-trihydroxy-27-methoxy-2,4,16,20,22,24,26-heptamethyl-10-[4-(2-methylpropyl)piperazin-1-yl]-12-({4-[(morpholin-4-yl)methyl]phenyl}methoxy)-1,6,15-trioxo-1,2,7,7a-tetrahydro-6H-2,7-(epoxypentadeca[1,11,13]trienoimino)[1]benzofuro[4,5-a]phenoxazin-25-yl acetate, DNA (5'-D(P*CP*TP*CP*GP*TP*AP*GP*AP*GP*TP*CP*CP*GP*TP*GP*TP*CP*A)-3'), DNA-directed RNA polymerase subunit alpha, ... Authors: Shin, Y, Murakami, K.S. Deposit date: 2021-11-28 Release date: 2022-07-13 Last modified: 2024-02-28 Method: ELECTRON MICROSCOPY (2.94 Å) Cite: Optimization of Benzoxazinorifamycins to Improve Mycobacterium tuberculosis RNA Polymerase Inhibition and Treatment of Tuberculosis. Acs Infect Dis., 8, 2022
7ML0	RNA polymerase II pre-initiation complex (PIC1) Descriptor: BJ4_G0050160.mRNA.1.CDS.1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB3, ... Authors: Yang, C, Fujiwara, R, Kim, H.J, Gorbea Colon, J.J, Steimle, S, Garcia, B.A, Murakami, K. Deposit date: 2021-04-27 Release date: 2022-02-02 Last modified: 2022-02-16 Method: ELECTRON MICROSCOPY (3 Å) Cite: Structural visualization of de novo transcription initiation by Saccharomyces cerevisiae RNA polymerase II. Mol.Cell, 82, 2022
7ML1	RNA polymerase II pre-initiation complex (PIC2) Descriptor: BJ4_G0050160.mRNA.1.CDS.1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB3, ... Authors: Yang, C, Fujiwara, R, Kim, H.J, Gorbea Colon, J.J, Steimle, S, Garcia, B.A, Murakami, K. Deposit date: 2021-04-27 Release date: 2022-02-02 Last modified: 2022-02-16 Method: ELECTRON MICROSCOPY (4 Å) Cite: Structural visualization of de novo transcription initiation by Saccharomyces cerevisiae RNA polymerase II. Mol.Cell, 82, 2022
7ML4	RNA polymerase II initially transcribing complex (ITC) Descriptor: BJ4_G0050160.mRNA.1.CDS.1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB3, ... Authors: Yang, C, Fujiwara, R, Kim, H.J, Gorbea Colon, J.J, Steimle, S, Garcia, B.A, Murakami, K. Deposit date: 2021-04-27 Release date: 2022-02-02 Last modified: 2022-03-09 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: Structural visualization of de novo transcription initiation by Saccharomyces cerevisiae RNA polymerase II. Mol.Cell, 82, 2022
1VY5	Crystal structure of the Thermus thermophilus 70S ribosome in the post-catalysis state of peptide bond formation containing dipeptydil-tRNA in the A site and deacylated tRNA in the P site. Descriptor: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... Authors: Polikanov, Y.S, Steitz, T.A, Innis, C.A. Deposit date: 2014-05-13 Release date: 2014-08-20 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (2.55 Å) Cite: A proton wire to couple aminoacyl-tRNA accommodation and peptide-bond formation on the ribosome. Nat.Struct.Mol.Biol., 21, 2014
1VY4	Crystal structure of the Thermus thermophilus 70S ribosome in the pre-attack state of peptide bond formation containing acylated tRNA-substrates in the A and P sites. Descriptor: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... Authors: Polikanov, Y.S, Steitz, T.A, Innis, C.A. Deposit date: 2014-05-13 Release date: 2014-08-20 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (2.6 Å) Cite: A proton wire to couple aminoacyl-tRNA accommodation and peptide-bond formation on the ribosome. Nat.Struct.Mol.Biol., 21, 2014
5DK5	Crystal structure of CRN-4-MES complex Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Cell death-related nuclease 4, ISOPROPYL ALCOHOL, ... Authors: Hsiao, Y.-Y, Yuan, H.S. Deposit date: 2015-09-03 Release date: 2016-08-24 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Identification of Inhibitors for the DEDDh Family of Exonucleases and a Unique Inhibition Mechanism by Crystal Structure Analysis of CRN-4 Bound with 2-Morpholin-4-ylethanesulfonate (MES) J.Med.Chem., 59, 2016
3ULJ	Crystal structure of apo Lin28B cold shock domain Descriptor: ACETATE ION, GLYCEROL, Lin28b, ... Authors: Mayr, F, Schuetz, A, Doege, N, Heinemann, U. Deposit date: 2011-11-10 Release date: 2012-08-15 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (1.06 Å) Cite: The Lin28 cold-shock domain remodels pre-let-7 microRNA. Nucleic Acids Res., 40, 2012
6ZTN	E. coli 70S-RNAP expressome complex in NusG-coupled state (42 nt intervening mRNA) Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... Authors: Webster, M.W, Takacs, M, Weixlbaumer, A. Deposit date: 2020-07-20 Release date: 2020-09-16 Last modified: 2024-04-24 Method: ELECTRON MICROSCOPY (3.9 Å) Cite: Structural basis of transcription-translation coupling and collision in bacteria. Science, 369, 2020
6ZTL	E. coli 70S-RNAP expressome complex in collided state bound to NusG Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... Authors: Webster, M.W, Takacs, M, Weixlbaumer, A. Deposit date: 2020-07-20 Release date: 2020-09-16 Last modified: 2024-04-24 Method: ELECTRON MICROSCOPY (3.5 Å) Cite: Structural basis of transcription-translation coupling and collision in bacteria. Science, 369, 2020
6ZTJ	E. coli 70S-RNAP expressome complex in NusG-coupled state (38 nt intervening mRNA) Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S1, ... Authors: Webster, M.W, Takacs, M, Weixlbaumer, A. Deposit date: 2020-07-20 Release date: 2020-09-16 Last modified: 2024-04-24 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: Structural basis of transcription-translation coupling and collision in bacteria. Science, 369, 2020
8WU8	Crystal structure of the human RAD9-RAD1(F64A/M256A/F266A)-HUS1-RHINO(88-99) complex Descriptor: Cell cycle checkpoint control protein RAD9A, Cell cycle checkpoint protein RAD1, Checkpoint protein HUS1, ... Authors: Hara, K, Nagata, K, Iida, N, Hashimoto, H. Deposit date: 2023-10-20 Release date: 2024-02-14 Last modified: 2024-03-27 Method: X-RAY DIFFRACTION (2.81 Å) Cite: Structural basis for intra- and intermolecular interactions on RAD9 subunit of 9-1-1 checkpoint clamp implies functional 9-1-1 regulation by RHINO. J.Biol.Chem., 300, 2024
3LH0	Crystal structure of the 53BP1 tandem tudor domain in complex with p53K372me2 Descriptor: DIMETHYLATED p53 LYSINE 372 PEPTIDE, SULFATE ION, TRIETHYLENE GLYCOL, ... Authors: Roy, S, Kutateladze, T.G. Deposit date: 2010-01-21 Release date: 2010-03-23 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Structural insight into p53 recognition by the 53BP1 tandem Tudor domain. J.Mol.Biol., 398, 2010
6ZTO	E. coli 70S-RNAP expressome complex in uncoupled state 1 Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... Authors: Webster, M.W, Takacs, M, Weixlbaumer, A. Deposit date: 2020-07-20 Release date: 2020-09-23 Last modified: 2024-04-24 Method: ELECTRON MICROSCOPY (3 Å) Cite: Structural basis of transcription-translation coupling and collision in bacteria. Science, 369, 2020
6ZU1	E. coli 70S-RNAP expressome complex in uncoupled state 2 Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... Authors: Webster, M.W, Takacs, M, Weixlbaumer, A. Deposit date: 2020-07-21 Release date: 2020-09-16 Last modified: 2024-04-24 Method: ELECTRON MICROSCOPY (3 Å) Cite: Structural basis of transcription-translation coupling and collision in bacteria. Science, 369, 2020
8SM3	Structure of Bacillus cereus VD045 Gabija GajA-GajB Complex Descriptor: Endonuclease GajA, Gabija protein GajB, SULFATE ION Authors: Antine, S.P, Mooney, S.E, Johnson, A.G, Kranzusch, P.J. Deposit date: 2023-04-25 Release date: 2023-11-22 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (3 Å) Cite: Structural basis of Gabija anti-phage defence and viral immune evasion. Nature, 625, 2024
4UA2	Crystal structure of dual function transcriptional regulator MerR from Bacillus megaterium MB1 Descriptor: Regulatory protein Authors: Lin, L.Y, Chang, C.C, Zou, X.W, Huang, C.C, Chan, N.L. Deposit date: 2014-08-07 Release date: 2015-07-22 Last modified: 2020-01-29 Method: X-RAY DIFFRACTION (2.61 Å) Cite: Structural basis of the mercury(II)-mediated conformational switching of the dual-function transcriptional regulator MerR Nucleic Acids Res., 43, 2015
4UA1	Crystal structure of dual function transcriptional regulator MerR form Bacillus megaterium MB1 in complex with mercury (II) ion Descriptor: MERCURY (II) ION, Regulatory protein Authors: Chang, C.C, Lin, L.Y, Zou, X.W, Huang, C.C, Chan, N.L. Deposit date: 2014-08-07 Release date: 2015-07-22 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (2.56 Å) Cite: Structural basis of the mercury(II)-mediated conformational switching of the dual-function transcriptional regulator MerR Nucleic Acids Res., 43, 2015
6ZTM	E. coli 70S-RNAP expressome complex in collided state without NusG Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... Authors: Webster, M.W, Takacs, M, Weixlbaumer, A. Deposit date: 2020-07-20 Release date: 2020-09-16 Last modified: 2024-04-24 Method: ELECTRON MICROSCOPY (3.3 Å) Cite: Structural basis of transcription-translation coupling and collision in bacteria. Science, 369, 2020
6QPJ	Human CLOCK PAS-A domain Descriptor: Circadian locomoter output cycles protein kaput Authors: Kwon, H, Freeman, S.L, Moody, P.C.E, Raven, E.L, Basran, J. Deposit date: 2019-02-14 Release date: 2019-09-25 Last modified: 2024-05-15 Method: X-RAY DIFFRACTION (2.315 Å) Cite: Heme binding to human CLOCK affects interactions with the E-box. Proc.Natl.Acad.Sci.USA, 116, 2019

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