8WU8

Crystal structure of the human RAD9-RAD1(F64A/M256A/F266A)-HUS1-RHINO(88-99) complex

Summary for 8WU8

Entry DOI	10.2210/pdb8wu8/pdb
Descriptor	Cell cycle checkpoint control protein RAD9A, Checkpoint protein HUS1, Cell cycle checkpoint protein RAD1, ... (4 entities in total)
Functional Keywords	dna damage, checkpoint, dna repair, dna binding clamp, cell cycle
Biological source	Homo sapiens (human) More
Total number of polymer chains	4
Total formula weight	95341.58
Authors	Hara, K.,Nagata, K.,Iida, N.,Hashimoto, H. (deposition date: 2023-10-20, release date: 2024-02-14, Last modification date: 2024-03-27)
Primary citation	Hara, K.,Tatsukawa, K.,Nagata, K.,Iida, N.,Hishiki, A.,Ohashi, E.,Hashimoto, H. Structural basis for intra- and intermolecular interactions on RAD9 subunit of 9-1-1 checkpoint clamp implies functional 9-1-1 regulation by RHINO. J.Biol.Chem., 300:105751-105751, 2024 Cited by PubMed: 38354779 DOI: 10.1016/j.jbc.2024.105751 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.81 Å)

Structure validation