5E9K
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5e9k by Molmil](/molmil-images/mine/5e9k) | |
6XG8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6xg8 by Molmil](/molmil-images/mine/6xg8) | ISCth4 transposase, pre-cleaved complex, PCC | Descriptor: | DNA (26-MER), Mutator family transposase | Authors: | Kosek, D, Dyda, F. | Deposit date: | 2020-06-17 | Release date: | 2020-10-14 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Structures of ISCth4 transpososomes reveal the role of asymmetry in copy-out/paste-in DNA transposition. Embo J., 40, 2021
|
|
5DQY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5dqy by Molmil](/molmil-images/mine/5dqy) | A fully oxidized human thioredoxin | Descriptor: | BENZOIC ACID, CHLORIDE ION, GLYCEROL, ... | Authors: | Hwang, J. | Deposit date: | 2015-09-15 | Release date: | 2015-12-23 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Crystal structure of fully oxidized human thioredoxin. Biochem.Biophys.Res.Commun., 467, 2015
|
|
5DTK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5dtk by Molmil](/molmil-images/mine/5dtk) | Fragments bound to the OXA-48 beta-lactamase: Compound 17 | Descriptor: | 1,2-ETHANEDIOL, 3,5-di(pyridin-4-yl)benzoic acid, Beta-lactamase, ... | Authors: | Lund, B.A, Christopeit, T, Leiros, H.-K.S. | Deposit date: | 2015-09-18 | Release date: | 2016-05-25 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.60000241 Å) | Cite: | Screening and Design of Inhibitor Scaffolds for the Antibiotic Resistance Oxacillinase-48 (OXA-48) through Surface Plasmon Resonance Screening. J.Med.Chem., 59, 2016
|
|
5E9L
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5e9l by Molmil](/molmil-images/mine/5e9l) | |
7C7A
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7c7a by Molmil](/molmil-images/mine/7c7a) | Cryo-EM structure of yeast Ribonuclease MRP with substrate ITS1 | Descriptor: | Internal Transcribed Spacer 1, MAGNESIUM ION, RNases MRP/P 32.9 kDa subunit, ... | Authors: | Lan, P, Wu, J, Lei, M. | Deposit date: | 2020-05-24 | Release date: | 2020-07-08 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Structural insight into precursor ribosomal RNA processing by ribonuclease MRP. Science, 369, 2020
|
|
7CEL
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7cel by Molmil](/molmil-images/mine/7cel) | CBH1 (E217Q) IN COMPLEX WITH CELLOHEXAOSE AND CELLOBIOSE | Descriptor: | 1,4-BETA-D-GLUCAN CELLOBIOHYDROLASE I, 2-acetamido-2-deoxy-beta-D-glucopyranose, COBALT (II) ION, ... | Authors: | Divne, C, Stahlberg, J, Jones, T.A. | Deposit date: | 1997-09-24 | Release date: | 1997-12-24 | Last modified: | 2021-11-03 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | High-resolution crystal structures reveal how a cellulose chain is bound in the 50 A long tunnel of cellobiohydrolase I from Trichoderma reesei. J.Mol.Biol., 275, 1998
|
|
5E0L
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5e0l by Molmil](/molmil-images/mine/5e0l) | LC8 - Chica (415-424) Complex | Descriptor: | Dynein light chain 1, cytoplasmic, Protein Chica peptide, ... | Authors: | Clark, S.A, Barbar, E.B, Karplus, P.A. | Deposit date: | 2015-09-29 | Release date: | 2015-12-30 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.31 Å) | Cite: | The Anchored Flexibility Model in LC8 Motif Recognition: Insights from the Chica Complex. Biochemistry, 55, 2016
|
|
6XGW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6xgw by Molmil](/molmil-images/mine/6xgw) | ISCth4 transposase, pre-reaction complex, PRC | Descriptor: | DNA (32-MER), Mutator family transposase | Authors: | Kosek, D, Dyda, F. | Deposit date: | 2020-06-18 | Release date: | 2020-10-14 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Structures of ISCth4 transpososomes reveal the role of asymmetry in copy-out/paste-in DNA transposition. Embo J., 40, 2021
|
|
5E9I
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5e9i by Molmil](/molmil-images/mine/5e9i) | |
5E9M
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5e9m by Molmil](/molmil-images/mine/5e9m) | |
6XGX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6xgx by Molmil](/molmil-images/mine/6xgx) | ISCth4 transposase, strand transfer complex 1, STC1 | Descriptor: | DNA (21-MER), DNA (25-MER), DNA (47-MER), ... | Authors: | Kosek, D, Dyda, F. | Deposit date: | 2020-06-18 | Release date: | 2020-10-14 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Structures of ISCth4 transpososomes reveal the role of asymmetry in copy-out/paste-in DNA transposition. Embo J., 40, 2021
|
|
3ECA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3eca by Molmil](/molmil-images/mine/3eca) | CRYSTAL STRUCTURE OF ESCHERICHIA COLI L-ASPARAGINASE, AN ENZYME USED IN CANCER THERAPY (ELSPAR) | Descriptor: | ASPARTIC ACID, L-asparaginase 2 | Authors: | Swain, A.L, Jaskolski, M, Housset, D, Rao, J.K.M, Wlodawer, A. | Deposit date: | 1993-07-02 | Release date: | 1993-10-31 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal structure of Escherichia coli L-asparaginase, an enzyme used in cancer therapy. Proc.Natl.Acad.Sci.USA, 90, 1993
|
|
6XF1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6xf1 by Molmil](/molmil-images/mine/6xf1) | |
3ENL
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3enl by Molmil](/molmil-images/mine/3enl) | |
2INE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2ine by Molmil](/molmil-images/mine/2ine) | |
6XIP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6xip by Molmil](/molmil-images/mine/6xip) | The 1.5 A Crystal Structure of the Co-factor Complex of NSP7 and the C-terminal Domain of NSP8 from SARS CoV-2 | Descriptor: | 1,2-ETHANEDIOL, Non-structural protein 7, Non-structural protein 8 | Authors: | Wilamowski, M, Kim, Y, Jedrzejczak, R, Maltseva, N, Endres, M, Godzik, A, Michalska, K, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2020-06-20 | Release date: | 2020-07-01 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Transient and stabilized complexes of Nsp7, Nsp8, and Nsp12 in SARS-CoV-2 replication. Biophys.J., 120, 2021
|
|
5EOZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5eoz by Molmil](/molmil-images/mine/5eoz) | Mutagenicity of 7-Benzyl guanine lesion and Replication by Human DNA Polymerase beta | Descriptor: | 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine, DNA (5'-D(*CP*CP*GP*AP*CP*(GFL)P*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3'), ... | Authors: | Koag, M.C, Lee, S. | Deposit date: | 2015-11-10 | Release date: | 2016-11-23 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.088 Å) | Cite: | Structural and kinetic studies of the effect of guanine-N7 alkylation and metal cofactors on DNA replication. Biochemistry, 2018
|
|
2IS7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2is7 by Molmil](/molmil-images/mine/2is7) | Crystal Structure of Aldose Reductase complexed with Dichlorophenylacetic acid | Descriptor: | (2,6-DICHLOROPHENYL)ACETIC ACID, Aldose reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | Authors: | Harrison, D.H.T, Milne, A, Brownlee, J.M. | Deposit date: | 2006-10-16 | Release date: | 2006-11-21 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural and thermodynamic studies of simple aldose reductase-inhibitor complexes. Bioorg.Chem., 34, 2006
|
|
6XYZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6xyz by Molmil](/molmil-images/mine/6xyz) | Crystal structure of the GH18 chitinase ChiB from the chitin utilization locus of Flavobacterium johnsoniae | Descriptor: | 1,2-ETHANEDIOL, Candidate chitinase Glycoside hydrolase family 18, FORMIC ACID | Authors: | Mazurkewich, S, Helland, R, MacKenzie, A, Eijsink, V, Pope, P, Branden, G, Larsbrink, J. | Deposit date: | 2020-01-31 | Release date: | 2020-09-02 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.63 Å) | Cite: | Structural insights of the enzymes from the chitin utilization locus of Flavobacterium johnsoniae. Sci Rep, 10, 2020
|
|
2DSV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2dsv by Molmil](/molmil-images/mine/2dsv) | Interactions of protective signalling factor with chitin-like polysaccharide: Crystal structure of the complex between signalling protein from sheep (SPS-40) and a hexasaccharide at 2.5A resolution | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Chitinase-3-like protein 1, alpha-D-mannopyranose-(1-4)-alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | Authors: | Srivastava, D.B, Ethayathulla, A.S, Kumar, J, Singh, N, Sharma, S, Bhushan, A, Srinivasan, A, Singh, T.P. | Deposit date: | 2006-07-07 | Release date: | 2006-08-01 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.54 Å) | Cite: | Carbohydrate binding properties and carbohydrate induced conformational switch in sheep secretory glycoprotein (SPS-40): crystal structures of four complexes of SPS-40 with chitin-like oligosaccharides J.Struct.Biol., 158, 2007
|
|
2ZM5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2zm5 by Molmil](/molmil-images/mine/2zm5) | Crystal structure of tRNA modification enzyme MiaA in the complex with tRNA(Phe) | Descriptor: | MAGNESIUM ION, tRNA delta(2)-isopentenylpyrophosphate transferase, tRNA(Phe) | Authors: | Sakai, J, Yao, M, Chimnaronk, S, Tanaka, I. | Deposit date: | 2008-04-11 | Release date: | 2009-04-14 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Snapshots of dynamics in synthesizing N(6)-isopentenyladenosine at the tRNA anticodon Biochemistry, 48, 2009
|
|
5ENM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5enm by Molmil](/molmil-images/mine/5enm) | Compound 10 | Descriptor: | (2~{R},4~{S},6~{S})-4-[2,4-bis(fluoranyl)-5-pyrimidin-5-yl-phenyl]-6-(3,5-dimethyl-1,2-oxazol-4-yl)-1,3-thiazinan-2-amine, Beta-secretase 1, GLYCEROL, ... | Authors: | Lewis, H.A. | Deposit date: | 2015-11-09 | Release date: | 2016-10-05 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.98 Å) | Cite: | Targeting the BACE1 Active Site Flap Leads to a Potent Inhibitor That Elicits Robust Brain A beta Reduction in Rodents. Acs Med.Chem.Lett., 7, 2016
|
|
5ENV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5env by Molmil](/molmil-images/mine/5env) | YEAST ALCOHOL DEHYDROGENASE WITH BOUND COENZYME | Descriptor: | Alcohol dehydrogenase 1, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, TRIFLUOROETHANOL, ... | Authors: | Plapp, B.V, Charlier Jr, H.A, Ramaswamy, S. | Deposit date: | 2015-11-09 | Release date: | 2015-11-25 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Mechanistic implications from structures of yeast alcohol dehydrogenase complexed with coenzyme and an alcohol. Arch.Biochem.Biophys., 591, 2015
|
|
7C79
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7c79 by Molmil](/molmil-images/mine/7c79) | Cryo-EM structure of yeast Ribonuclease MRP | Descriptor: | MAGNESIUM ION, RNases MRP/P 32.9 kDa subunit, Ribonuclease MRP RNA subunit NME1, ... | Authors: | Lan, P, Wu, J, Lei, M. | Deposit date: | 2020-05-24 | Release date: | 2020-07-08 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (2.5 Å) | Cite: | Structural insight into precursor ribosomal RNA processing by ribonuclease MRP. Science, 369, 2020
|
|