6XF1

Nesprin-2G(aa1425-1649)-FHOD1(aa1-339) complex, H. sapiens

Summary for 6XF1

• Entry DOI: 10.2210/pdb6xf1/pdb
• Related: 6XF2
• Descriptor: Nesprin-2, FH1/FH2 domain-containing protein 1 (3 entities in total)
• Functional Keywords: spectrin repeat, fh3 domain, armadillo repeat, scaffold protein, nuclear positioning, transmembrane, actin-associated nuclear line, structural protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 4
• Total formula weight: 125048.77

Authors

Lim, S.M.,Schwartz, T.U. (deposition date: 2020-06-15, release date: 2021-02-03, Last modification date: 2023-10-18)

• Primary citation: Lim, S.M.,Cruz, V.E.,Antoku, S.,Gundersen, G.G.,Schwartz, T.U.; Structures of FHOD1-Nesprin1/2 complexes reveal alternate binding modes for the FH3 domain of formins.; Structure, 29:540-552.e5, 2021; PubMed: 33472039; DOI: 10.1016/j.str.2020.12.013

Experimental method

X-RAY DIFFRACTION (2.8 Å)