8HO2
 
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1H2Z
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5OL1
 | | Crystal structure of an inactivated Ssp SICLOPPS intein with a CAFHPQ extein | | Descriptor: | 1,2-ETHANEDIOL, BETA-MERCAPTOETHANOL, DNA polymerase III subunit alpha,DNA polymerase III subunit alpha, ... | | Authors: | Kick, L.M, Schneider, S. | | Deposit date: | 2017-07-26 | | Release date: | 2017-09-27 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (1.751 Å) | | Cite: | Mechanistic Insights into Cyclic Peptide Generation by DnaE Split-Inteins through Quantitative and Structural Investigation.
Chembiochem, 18, 2017
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5OC2
 | | Crystal structure of Asp295Cys/Lys303Cys Amadoriase I mutant from Aspergillus Fumigatus | | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, Fructosyl amine:oxygen oxidoreductase | | Authors: | Rigoldi, F, Donini, S, Gautieri, A, Parisini, E. | | Deposit date: | 2017-06-29 | | Release date: | 2018-02-28 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.85 Å) | | Cite: | Thermal stabilization of the deglycating enzyme Amadoriase I by rational design.
Sci Rep, 8, 2018
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2XBF
 | | Nedd4 HECT structure | | Descriptor: | 1,2-ETHANEDIOL, CALCIUM ION, E3 UBIQUITIN-PROTEIN LIGASE NEDD4 | | Authors: | Maspero, E, Cecatiello, V, Musacchio, A, Polo, S, Pasqualato, S. | | Deposit date: | 2010-04-09 | | Release date: | 2011-03-23 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.503 Å) | | Cite: | Structure of the Hect:Ubiquitin Complex and its Role in Ubiquitin Chain Elongation
Embo Rep., 12, 2011
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7ND1
 | | First-in-class small molecule inhibitors of Polycomb Repressive Complex 1 (PRC1) RING domain | | Descriptor: | 3-(2-chlorophenyl)-4-ethyl-5-(1~{H}-indol-4-yl)-1~{H}-pyrrole-2-carboxylic acid, E3 ubiquitin-protein ligase RING2, Polycomb complex protein BMI-1, ... | | Authors: | Cierpicki, T, Lund, G, Jaremko, L. | | Deposit date: | 2021-01-29 | | Release date: | 2021-06-16 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Small-molecule inhibitors targeting Polycomb repressive complex 1 RING domain.
Nat.Chem.Biol., 17, 2021
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8ISQ
 | | Crystal structure of extended-spectrum class A beta-lactamase, CESS-1 E166Q acylated by ampicillin | | Descriptor: | (2R,4S)-2-[(R)-{[(2R)-2-amino-2-phenylacetyl]amino}(carboxy)methyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Beta-lactamase, ... | | Authors: | Jeong, B.G, Kim, M.Y, Jeong, C.S, Do, H.W, Lee, J.H, Cha, S.S. | | Deposit date: | 2023-03-21 | | Release date: | 2024-05-15 | | Method: | X-RAY DIFFRACTION (2.24 Å) | | Cite: | Characterization of the extended substrate spectrum of the class A beta-lactamase CESS-1 from Stenotrophomonas sp. and structure-based investigation into its substrate preference.
Int J Antimicrob Agents, 63, 2024
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8ISP
 | | Crystal structure of extended-spectrum class A beta-lactamase, CESS-1 E166Q acylated by cephalexin | | Descriptor: | (R)-2-((R)-((R)-2-amino-2-phenylacetamido)(carboxy)methyl)-5-methyl-3,6-dihydro-2H-1,3-thiazine-4-carboxylic acid, Beta-lactamase | | Authors: | Jeong, B.G, Kim, M.Y, Jeong, C.S, Do, H.W, Lee, J.H, Cha, S.S. | | Deposit date: | 2023-03-21 | | Release date: | 2024-05-15 | | Method: | X-RAY DIFFRACTION (2.11 Å) | | Cite: | Characterization of the extended substrate spectrum of the class A beta-lactamase CESS-1 from Stenotrophomonas sp. and structure-based investigation into its substrate preference.
Int J Antimicrob Agents, 63, 2024
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8ISO
 | | Crystal structure of extended-spectrum class A beta-lactamase, CESS-1 | | Descriptor: | 1,2-ETHANEDIOL, 1-METHOXY-2-[2-(2-METHOXY-ETHOXY]-ETHANE, Beta-lactamase | | Authors: | Jeong, B.G, Kim, M.Y, Jeong, C.S, Do, H.W, Lee, J.H, Cha, S.S. | | Deposit date: | 2023-03-21 | | Release date: | 2024-05-15 | | Method: | X-RAY DIFFRACTION (1.29 Å) | | Cite: | Characterization of the extended substrate spectrum of the class A beta-lactamase CESS-1 from Stenotrophomonas sp. and structure-based investigation into its substrate preference.
Int J Antimicrob Agents, 63, 2024
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8ISR
 | | Crystal structure of extended-spectrum class A beta-lactamase, CESS-1 E166Q acylated by cefaclor | | Descriptor: | (R)-2-((R)-((R)-2-amino-2-phenylacetamido)(carboxy)methyl)-5-chloro-3,6-dihydro-2H-1,3-thiazine-4-carboxylic acid, 1,2-ETHANEDIOL, Beta-lactamase | | Authors: | Jeong, B.G, Kim, M.Y, Jeong, C.S, Do, H.W, Lee, J.H, Cha, S.S. | | Deposit date: | 2023-03-21 | | Release date: | 2024-05-15 | | Method: | X-RAY DIFFRACTION (2.09 Å) | | Cite: | Characterization of the extended substrate spectrum of the class A beta-lactamase CESS-1 from Stenotrophomonas sp. and structure-based investigation into its substrate preference.
Int J Antimicrob Agents, 63, 2024
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6XP9
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5OL7
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8THO
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8IJM
 | | Cyo-EM structure of K794A non-gastric proton pump in Na+ bound E1AMPPCP state | | Descriptor: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL, ... | | Authors: | Abe, K. | | Deposit date: | 2023-02-27 | | Release date: | 2023-08-02 | | Last modified: | 2023-08-09 | | Method: | ELECTRON MICROSCOPY (3.13 Å) | | Cite: | An unusual conformation from Na + -sensitive non-gastric proton pump mutants reveals molecular mechanisms of cooperative Na + -binding.
Biochim Biophys Acta Mol Cell Res, 1870, 2023
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3UG3
 | | Crystal structure of alpha-L-arabinofuranosidase from Thermotoga maritima ligand free form | | Descriptor: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Alpha-L-arabinofuranosidase, ... | | Authors: | Im, D.-H, Miyazaki, K, Wakagi, T, Fushinobu, S. | | Deposit date: | 2011-11-02 | | Release date: | 2012-03-07 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Crystal Structures of Glycoside Hydrolase Family 51 alpha-L-Arabinofuranosidase from Thermotoga maritima
Biosci.Biotechnol.Biochem., 76, 2012
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8IJL
 | | Cyo-EM structure of wildtype non-gastric proton pump in the presence of Na+, AlF and ADP | | Descriptor: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-{[(4-O-alpha-D-glucopyranosyl-alpha-D-glucopyranosyl)oxy]methyl}-4-{[(3beta,9beta,14beta,17beta,25R)-spirost-5-en-3-yl]oxy}butyl 4-O-alpha-D-glucopyranosyl-alpha-D-glucopyranoside, ... | | Authors: | Abe, K. | | Deposit date: | 2023-02-27 | | Release date: | 2023-10-18 | | Method: | ELECTRON MICROSCOPY (2.62 Å) | | Cite: | An unusual conformation from Na + -sensitive non-gastric proton pump mutants reveals molecular mechanisms of cooperative Na + -binding.
Biochim Biophys Acta Mol Cell Res, 1870, 2023
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7QEK
 | | Structure of the ligand binding domain of the antibiotic biosynthesis regulator AdmX from the rhizobacterium Serratia plymuthica A153 bound to the auxin indole-3-piruvic acid (IPA). | | Descriptor: | 3-(1H-INDOL-3-YL)-2-OXOPROPANOIC ACID, MAGNESIUM ION, regulator AdmX | | Authors: | Gavira, J.A, Rico-Jimenez, M, Castellvi, A, Krell, T, Matilla, M.A. | | Deposit date: | 2021-12-03 | | Release date: | 2022-12-14 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.25 Å) | | Cite: | Emergence of an Auxin Sensing Domain in Plant-Associated Bacteria.
Mbio, 14, 2023
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8I6U
 | | The cryo-EM structure of OsCyc1 dimer state | | Descriptor: | Syn-copalyl diphosphate synthase, chloroplastic | | Authors: | Ma, X.L, Xu, H.F, Tong, Y.R, Luo, Y.F, Dong, Q.H, Jiang, T. | | Deposit date: | 2023-01-29 | | Release date: | 2023-12-06 | | Method: | ELECTRON MICROSCOPY (7.9 Å) | | Cite: | Structural and functional investigations of syn-copalyl diphosphate synthase from Oryza sativa.
Commun Chem, 6, 2023
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7BEA
 | | Structure of human Programmed cell death 1 ligand 1 (PD-L1) with inhibitor | | Descriptor: | 2-(aminomethyl)-6-[(2-methyl-3-phenyl-phenyl)methoxy]-~{N}-(2-phenylethyl)imidazo[1,2-a]pyridin-3-amine, Programmed cell death 1 ligand 1 | | Authors: | Magiera-Mularz, K, Butera, R, Wazynska, M, Holak, T, Domling, A. | | Deposit date: | 2020-12-22 | | Release date: | 2021-06-09 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (2.45 Å) | | Cite: | Design, Synthesis, and Biological Evaluation of Imidazopyridines as PD-1/PD-L1 Antagonists.
Acs Med.Chem.Lett., 12, 2021
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8I6T
 | | The cryo-EM structure of OsCyc1 hexamer state | | Descriptor: | Syn-copalyl diphosphate synthase, chloroplastic | | Authors: | Ma, X.L, Xu, H.F, Tong, Y.R, Luo, Y.F, Dong, Q.H, Jiang, T. | | Deposit date: | 2023-01-29 | | Release date: | 2023-12-06 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | Structural and functional investigations of syn-copalyl diphosphate synthase from Oryza sativa.
Commun Chem, 6, 2023
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8I6P
 | | The cryo-EM structure of OsCyc1 tetramer state | | Descriptor: | Syn-copalyl diphosphate synthase, chloroplastic | | Authors: | Ma, X.L, Xu, H.F, Tong, Y.R, Luo, Y.F, Dong, Q.H, Jiang, T. | | Deposit date: | 2023-01-29 | | Release date: | 2023-12-06 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Structural and functional investigations of syn-copalyl diphosphate synthase from Oryza sativa.
Commun Chem, 6, 2023
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8IH5
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5FG0
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8RAJ
 | | NMR structure of PKS docking domains | | Descriptor: | Beta-ketoacyl synthase, Trimethylamine monooxygenase | | Authors: | Scat, S, Weissman, K.J, Chagot, B. | | Deposit date: | 2023-12-01 | | Release date: | 2024-06-05 | | Last modified: | 2024-07-17 | | Method: | SOLUTION NMR | | Cite: | Insights into docking in megasynthases from the investigation of the toblerol trans -AT polyketide synthase: many alpha-helical means to an end.
Rsc Chem Biol, 5, 2024
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5OL6
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