8ISO

Crystal structure of extended-spectrum class A beta-lactamase, CESS-1

Summary for 8ISO

• Entry DOI: 10.2210/pdb8iso/pdb
• Related: 1O7E
• Descriptor: Beta-lactamase, 1,2-ETHANEDIOL, 1-METHOXY-2-[2-(2-METHOXY-ETHOXY]-ETHANE, ... (4 entities in total)
• Functional Keywords: hydrolase, extended-spectrum class a beta-lactamase
• Biological source: Stenotrophomonas sp. KCTC 12332
• Total number of polymer chains: 1
• Total formula weight: 29886.65

Authors

Jeong, B.G.,Kim, M.Y.,Jeong, C.S.,Do, H.W.,Lee, J.H.,Cha, S.S. (deposition date: 2023-03-21, release date: 2024-05-15)

• Primary citation: Jeong, B.G.,Kim, M.Y.,Jeong, C.S.,Do, H.,Hwang, J.,Lee, J.H.,Cha, S.S.; Characterization of the extended substrate spectrum of the class A beta-lactamase CESS-1 from Stenotrophomonas sp. and structure-based investigation into its substrate preference.; Int J Antimicrob Agents, 63:107171-107171, 2024; PubMed: 38588869; DOI: 10.1016/j.ijantimicag.2024.107171

Experimental method

X-RAY DIFFRACTION (1.29 Å)