1H2Z

PROLYL OLIGOPEPTIDASE FROM PORCINE BRAIN, S554A MUTANT WITH BOUND PEPTIDE LIGAND SUC-GLY-PRO

Summary for 1H2Z
Related1E5T 1E8M 1E8N 1H2W 1H2X 1H2Y 1O6F 1O6G 1QFM 1QFS
DescriptorPROLYL ENDOPEPTIDASE, GLYCINE, PROLINE, ... (6 entities in total)
Functional Keywordshydrolase, prolyl oligopeptidase, amnesia, alpha/ beta-hydrolase, beta-propeller, serine protease
Biological sourceSUS SCROFA (PIG)
Total number of polymer chains1
Total formula weight81432.91
Authors
Rea, D.,Fulop, V. (deposition date: 2002-08-20, release date: 2002-11-11, Last modification date: 2018-06-20)
Primary citationFulop, V.,Polgar, L.,Rea, D.,Renner, V.,Szeltner, Z.
Electrostatic Effects and Binding Determinants in the Catalysis of Prolyl Oligopeptidase: Site Specific Mutagenesis at the Oxyanion Binding Site
J.Biol.Chem., 277:42613-, 2002
PubMed: 12202494
DOI: 110.1074/JBC.M208043200
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.65 Å)
Structure validation
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PDB entries from 2021-06-16