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3REK
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BU of 3rek by Molmil
2.6 Angstrom Crystal Structure of the Nucleosome Core Particle Assembled with a 146 bp Alpha-Satellite DNA (NCP146b) Derivatized with Oxaliplatin
Descriptor: DNA (146-MER), Histone H2A type1, Histone H2B 1.1, ...
Authors:Wu, B, Davey, C.A.
Deposit date:2011-04-04
Release date:2012-03-14
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Specific DNA structural attributes modulate platinum anticancer drug site selection and cross-link generation.
Nucleic Acids Res., 39, 2011
3REJ
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BU of 3rej by Molmil
2.55 Angstrom Crystal Structure of the Nucleosome Core Particle Assembled with a 146 bp Alpha-Satellite DNA (NCP146b)
Descriptor: DNA (146-MER), Histone H2A type 1, Histone H2B 1.1, ...
Authors:Wu, B, Davey, C.A.
Deposit date:2011-04-04
Release date:2012-03-14
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Specific DNA structural attributes modulate platinum anticancer drug site selection and cross-link generation.
Nucleic Acids Res., 39, 2011
1MUF
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BU of 1muf by Molmil
Structure of histone H3 K4-specific methyltransferase SET7/9
Descriptor: SET9
Authors:Jacobs, S.A, Harp, J.M, Devarakonda, S, Kim, Y, Rastinejad, F, Khorasanizadeh, S.
Deposit date:2002-09-23
Release date:2002-11-06
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:The active site of the SET domain is constructed on a knot
Nat.Struct.Biol., 9, 2002
3REL
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BU of 3rel by Molmil
2.7 Angstrom Crystal Structure of the Nucleosome Core Particle Assembled with a 146 bp Alpha-Satellite DNA (NCP146b) Derivatized with Triamminechloroplatinum(II) Chloride
Descriptor: DNA (146-MER), Histone H2A, Histone H2B 1.1, ...
Authors:Wu, B, Davey, C.A.
Deposit date:2011-04-04
Release date:2012-03-14
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Specific DNA structural attributes modulate platinum anticancer drug site selection and cross-link generation.
Nucleic Acids Res., 39, 2011
1MT6
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BU of 1mt6 by Molmil
Structure of histone H3 K4-specific methyltransferase SET7/9 with AdoHcy
Descriptor: S-ADENOSYL-L-HOMOCYSTEINE, SET9
Authors:Jacobs, S.A, Harp, J.M, Devarakonda, S, Kim, Y, Rastinejad, F, Khorasanizadeh, S.
Deposit date:2002-09-20
Release date:2002-11-06
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The active site of the SET domain is constructed on a knot
Nat.Struct.Biol., 9, 2002
3REI
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BU of 3rei by Molmil
2.65 Angstrom Crystal Structure of the Nucleosome Core Particle Assembled with a 145 bp Alpha-Satellite DNA (NCP145) Derivatized with Triamminechloroplatinum(II) Chloride
Descriptor: DNA (145-MER), Histone H2A type1, Histone H2B 1.1, ...
Authors:Wu, B, Davey, C.A.
Deposit date:2011-04-04
Release date:2012-03-14
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Specific DNA structural attributes modulate platinum anticancer drug site selection and cross-link generation.
Nucleic Acids Res., 39, 2011
2L7P
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BU of 2l7p by Molmil
ASHH2 a CW domain
Descriptor: Histone-lysine N-methyltransferase ASHH2, ZINC ION
Authors:Kristiansen, P, Hoppmann, V, Thorstensen, T, Aalen, R.B, Aasland, R, Finne, K, Veiseth, S.
Deposit date:2010-12-16
Release date:2011-05-11
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:The CW domain, a new histone recognition module in chromatin proteins.
Embo J., 30, 2011
3REH
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BU of 3reh by Molmil
2.5 Angstrom Crystal Structure of the Nucleosome Core Particle Assembled with a 145 bp Alpha-Satellite DNA (NCP145)
Descriptor: DNA (145-MER), Histone H2A type 1, Histone H2B 1.1, ...
Authors:Wu, B, Davey, C.A.
Deposit date:2011-04-04
Release date:2012-03-14
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Specific DNA structural attributes modulate platinum anticancer drug site selection and cross-link generation.
Nucleic Acids Res., 39, 2011
7VBM
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BU of 7vbm by Molmil
The mouse nucleosome structure containing H3mm18 aided by PL2-6 scFv
Descriptor: DNA (126-MER), Histone H2A type 1-B, Histone H2B type 3-A, ...
Authors:Hirai, S, Takizawa, Y, Kujirai, T, Kurumizaka, H.
Deposit date:2021-08-31
Release date:2022-01-19
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Unusual nucleosome formation and transcriptome influence by the histone H3mm18 variant.
Nucleic Acids Res., 50, 2022
7S7F
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BU of 7s7f by Molmil
STRUCTURE OF HLA-B*07:02 IN COMPLEX WITH DOT1L(998-1006) PHOSPHOPEPTIDE
Descriptor: Beta-2-microglobulin, HLA class I histocompatibility antigen, B-7 alpha chain, ...
Authors:Patskovska, L, Patskovsky, Y, Nyovanie, S, Natarajan, A, Joshi, B, Morin, B, Brittsan, C, Huber, O, Gordon, S, Michelet, X, Schmitzberger, F, Stein, R, Findeis, M, Hurwitz, A, Van Dijk, M, Buell, J, Underwood, D, Krogsgaard, M.
Deposit date:2021-09-15
Release date:2022-11-02
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:Molecular mechanism of phosphopeptide neoantigen immunogenicity.
Nat Commun, 14, 2023
7S7E
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BU of 7s7e by Molmil
STRUCTURE OF HLA-B*07:02 IN COMPLEX WITH DOT1L(998-1006) PEPTIDE
Descriptor: Beta-2-microglobulin, HLA class I histocompatibility antigen, B-7 alpha chain, ...
Authors:Patskovska, L, Patskovsky, Y, Nyovanie, S, Natarajan, A, Joshi, B, Morin, B, Brittsan, C, Huber, O, Gordon, S, Michelet, X, Schmitzberger, F, Stein, R, Findeis, M, Hurwitz, A, Van Dijk, M, Buell, J, Underwood, D, Krogsgaard, M.
Deposit date:2021-09-15
Release date:2022-11-02
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.04 Å)
Cite:Molecular mechanism of phosphopeptide neoantigen immunogenicity.
Nat Commun, 14, 2023
8IHN
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BU of 8ihn by Molmil
Cryo-EM structure of the Rpd3S core complex
Descriptor: CALCIUM ION, Chromatin modification-related protein EAF3, Histone H3, ...
Authors:Zhang, Y, Gang, C.
Deposit date:2023-02-23
Release date:2024-03-20
Method:ELECTRON MICROSCOPY (3.37 Å)
Cite:Structural basis for nucleosome binding and catalysis by the yeast Rpd3S/HDAC holoenzyme.
Cell Res., 33, 2023
6FQ8
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BU of 6fq8 by Molmil
Class 3 : translocated nucleosome
Descriptor: DNA (147-MER), Histone H2A, Histone H2B, ...
Authors:Bilokapic, S, Halic, M.
Deposit date:2018-02-13
Release date:2018-04-18
Last modified:2025-07-02
Method:ELECTRON MICROSCOPY (4.8 Å)
Cite:Structural rearrangements of the histone octamer translocate DNA.
Nat Commun, 9, 2018
8UT3
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BU of 8ut3 by Molmil
CryoEM structure of A/Perth/16/2009 H3 in complex with flu HA central stem VH1-18 antibody UCA6
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ...
Authors:Huang, J, Han, J, Ward, A.B.
Deposit date:2023-10-30
Release date:2024-05-08
Last modified:2024-11-20
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Eliciting a single amino acid change by vaccination generates antibody protection against group 1 and group 2 influenza A viruses.
Immunity, 57, 2024
6FQ6
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BU of 6fq6 by Molmil
Class 2 : distorted nucleosome
Descriptor: DNA (147-MER), Histone H2A, Histone H2B, ...
Authors:Bilokapic, S, Halic, M.
Deposit date:2018-02-13
Release date:2018-04-18
Last modified:2025-07-02
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Structural rearrangements of the histone octamer translocate DNA.
Nat Commun, 9, 2018
6FQ5
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BU of 6fq5 by Molmil
Class 1 : canonical nucleosome
Descriptor: DNA (147-MER), Histone H2A, Histone H2B, ...
Authors:Bilokapic, S, Halic, M.
Deposit date:2018-02-13
Release date:2018-04-18
Last modified:2025-07-02
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structural rearrangements of the histone octamer translocate DNA.
Nat Commun, 9, 2018
5I1A
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BU of 5i1a by Molmil
CRYSTAL STRUCTURE OF HUMAN GERMLINE ANTIBODY IGHV3-23/IGKV3-11
Descriptor: ACETATE ION, CNTO388 HEAVY CHAIN, CNTO388 LIGHT CHAIN, ...
Authors:Teplyakov, A, Obmolova, G, Malia, T, Luo, J, Gilliland, G.
Deposit date:2016-02-05
Release date:2016-06-08
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural diversity in a human antibody germline library.
Mabs, 8, 2016
7T7L
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BU of 7t7l by Molmil
Structure of human G9a SET-domain (EHMT2) in complex with covalent inhibitor (Compound 1)
Descriptor: Histone-lysine N-methyltransferase EHMT2, N-(6-methoxy-4-{[1-(propan-2-yl)piperidin-4-yl]amino}-7-[3-(pyrrolidin-1-yl)propoxy]quinazolin-2-yl)prop-2-enamide, N-(6-methoxy-4-{[1-(propan-2-yl)piperidin-4-yl]amino}-7-[3-(pyrrolidin-1-yl)propoxy]quinazolin-2-yl)propanamide, ...
Authors:Park, K.-S, Kumar, P.
Deposit date:2021-12-15
Release date:2022-07-06
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Discovery of the First-in-Class G9a/GLP Covalent Inhibitors.
J.Med.Chem., 65, 2022
7XCT
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BU of 7xct by Molmil
Cryo-EM structure of Dot1L and H2BK34ub-H3K79Nle nucleosome 2:1 complex
Descriptor: DNA (145-MER), Histone H2A, Histone H2B type 1-K, ...
Authors:Ai, H.S, Liu, A.J, Lou, Z.Y, Liu, L.
Deposit date:2022-03-25
Release date:2022-04-20
Last modified:2024-11-06
Method:ELECTRON MICROSCOPY (2.72 Å)
Cite:H2B Lys34 Ubiquitination Induces Nucleosome Distortion to Stimulate Dot1L Activity.
Nat.Chem.Biol., 18, 2022
7XCR
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BU of 7xcr by Molmil
Cryo-EM structure of Dot1L and H2BK34ub-H3K79Nle nucleosome 1:1 complex
Descriptor: DNA (146-MER), Histone H2A, Histone H2B type 1-K, ...
Authors:Ai, H.S, Liu, A.J, Lou, Z.Y, Liu, L.
Deposit date:2022-03-25
Release date:2022-04-20
Last modified:2025-06-25
Method:ELECTRON MICROSCOPY (2.57 Å)
Cite:H2B Lys34 Ubiquitination Induces Nucleosome Distortion to Stimulate Dot1L Activity.
Nat.Chem.Biol., 18, 2022
7XD1
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BU of 7xd1 by Molmil
cryo-EM structure of unmodified nucleosome
Descriptor: DNA (147-MER), Histone H2A type 1-B/E, Histone H2B type 1-K, ...
Authors:Ai, H.S, Liu, A.J, Lou, Z.Y, Liu, L.
Deposit date:2022-03-26
Release date:2022-04-20
Last modified:2024-06-26
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:H2B Lys34 Ubiquitination Induces Nucleosome Distortion to Stimulate Dot1L Activity.
Nat.Chem.Biol., 18, 2022
7T7M
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BU of 7t7m by Molmil
Structure of human GLP SET-domain (EHMT1) in complex with covalent inhibitor (Compound 1)
Descriptor: Histone-lysine N-methyltransferase EHMT1, N-(6-methoxy-4-{[1-(propan-2-yl)piperidin-4-yl]amino}-7-[3-(pyrrolidin-1-yl)propoxy]quinazolin-2-yl)prop-2-enamide, N-(6-methoxy-4-{[1-(propan-2-yl)piperidin-4-yl]amino}-7-[3-(pyrrolidin-1-yl)propoxy]quinazolin-2-yl)propanamide, ...
Authors:Park, K.-S, Kumar, P.
Deposit date:2021-12-15
Release date:2022-07-06
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Discovery of the First-in-Class G9a/GLP Covalent Inhibitors.
J.Med.Chem., 65, 2022
3EG6
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BU of 3eg6 by Molmil
Structure of WDR5 bound to MLL1 peptide
Descriptor: MLL-1 peptide, SULFATE ION, WD repeat-containing protein 5
Authors:Patel, A, Dharmarajan, V, Cosgrove, M.S.
Deposit date:2008-09-10
Release date:2008-09-30
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:Structure of WDR5 bound to mixed lineage leukemia protein-1 peptide.
J.Biol.Chem., 283, 2008
7TRM
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BU of 7trm by Molmil
Crystal structure of human BIRC2 BIR3 domain in complex with inhibitor LCL-161
Descriptor: 1,2-ETHANEDIOL, Baculoviral IAP repeat-containing protein 2, LCL-161, ...
Authors:Tencer, A.H, Klein, B.J, Kutateladze, T.G.
Deposit date:2022-01-29
Release date:2023-08-02
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Molecular basis for nuclear accumulation and targeting of the inhibitor of apoptosis BIRC2.
Nat.Struct.Mol.Biol., 30, 2023
5T1G
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BU of 5t1g by Molmil
chromo shadow domain of CBX1 in complex with a histone peptide
Descriptor: Chromobox protein homolog 1, Histone H3.1, UNKNOWN ATOM OR ION
Authors:Liu, Y, Tempel, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
Deposit date:2016-08-19
Release date:2016-09-14
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:chromo shadow domain of CBX1 in complex with a histone peptide
To Be Published

238582

數據於2025-07-09公開中

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