6XU1
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![BU of 6xu1 by Molmil](/molmil-images/mine/6xu1) | Crystal structure of tetrameric human H215A-SAMHD1 (residues 109-626) with GTP, dAMPNPP and Mg | Descriptor: | 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]adenosine, Deoxynucleoside triphosphate triphosphohydrolase SAMHD1, FE (III) ION, ... | Authors: | Morris, E.R, Kunzelmann, S, Caswell, S.J, Arnold, L.H, Purkiss, A.G, Kelly, G, Taylor, I.A. | Deposit date: | 2020-01-17 | Release date: | 2020-06-24 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structures of SAMHD1 inhibitor complexes reveal the mechanism of water-mediated dNTP hydrolysis. Nat Commun, 11, 2020
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7NF8
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![BU of 7nf8 by Molmil](/molmil-images/mine/7nf8) | Ovine (b0,+AT-rBAT)2 hetero-tetramer, asymmetric unit, rigid-body fitted | Descriptor: | 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Lee, Y, Kuehlbrandt, W. | Deposit date: | 2021-02-05 | Release date: | 2022-01-19 | Last modified: | 2022-06-08 | Method: | ELECTRON MICROSCOPY (2.83 Å) | Cite: | Ca 2+ -mediated higher-order assembly of heterodimers in amino acid transport system b 0,+ biogenesis and cystinuria. Nat Commun, 13, 2022
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5BOJ
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![BU of 5boj by Molmil](/molmil-images/mine/5boj) | Crystal Structure of Human Transthyretin in Complex with Gemfibrozil | Descriptor: | 5-(2,5-dimethylphenoxy)-2,2-dimethylpentanoic acid, SODIUM ION, Transthyretin | Authors: | Begum, A, Olofsson, A, Sauer-Eriksson, A.E. | Deposit date: | 2015-05-27 | Release date: | 2015-08-05 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Enthalpic Forces Correlate with the Selectivity of Transthyretin-Stabilizing Ligands in Human Plasma. J.Med.Chem., 58, 2015
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4XYJ
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![BU of 4xyj by Molmil](/molmil-images/mine/4xyj) | Crystal structure of human phosphofructokinase-1 in complex with ATP and Mg, Northeast Structural Genomics Consortium Target HR9275 | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent 6-phosphofructokinase, platelet type, ... | Authors: | Forouhar, F, Webb, B.A, Szu, F.-E, Seetharaman, J, Barber, D.L, Tong, L, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2015-02-02 | Release date: | 2015-05-20 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Structures of human phosphofructokinase-1 and atomic basis of cancer-associated mutations. Nature, 523, 2015
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6UXH
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![BU of 6uxh by Molmil](/molmil-images/mine/6uxh) | |
7D32
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![BU of 7d32 by Molmil](/molmil-images/mine/7d32) | The TBA-Pb2+ complex in P41212 space group | Descriptor: | DNA (5'-D(*GP*GP*TP*TP*GP*GP*TP*GP*TP*GP*GP*TP*TP*GP*G)-3'), LEAD (II) ION | Authors: | Liu, H.H, Gao, Y.Q, Sheng, J, Gan, J.H. | Deposit date: | 2020-09-18 | Release date: | 2021-09-22 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.707 Å) | Cite: | Structure-guided development of Pb 2+ -binding DNA aptamers. Sci Rep, 12, 2022
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7D31
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![BU of 7d31 by Molmil](/molmil-images/mine/7d31) | The TBA-Pb2+ complex in P41212 space group | Descriptor: | DNA (5'-D(*GP*GP*TP*TP*GP*GP*TP*GP*TP*GP*GP*TP*TP*GP*G)-3'), LEAD (II) ION | Authors: | Liu, H.H, Gao, Y.Q, Sheng, J, Gan, J.H. | Deposit date: | 2020-09-18 | Release date: | 2021-09-22 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (1.396 Å) | Cite: | Structure-guided development of Pb 2+ -binding DNA aptamers. Sci Rep, 12, 2022
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7D33
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![BU of 7d33 by Molmil](/molmil-images/mine/7d33) | The Pb2+ complexed structure of TBA G8C mutant | Descriptor: | DNA (5'-D(*GP*GP*TP*TP*GP*GP*TP*CP*TP*GP*GP*TP*TP*GP*G)-3'), LEAD (II) ION | Authors: | Liu, H.H, Gao, Y.Q, Sheng, J, Gan, J.H. | Deposit date: | 2020-09-18 | Release date: | 2021-09-22 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.117 Å) | Cite: | Structure-guided development of Pb 2+ -binding DNA aptamers. Sci Rep, 12, 2022
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6MGT
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![BU of 6mgt by Molmil](/molmil-images/mine/6mgt) | Crystal structure of alpha-Amino-beta-Carboxymuconate-epsilon-Semialdehyde Decarboxylase Mutant H110A | Descriptor: | 2-amino-3-carboxymuconate 6-semialdehyde decarboxylase, COBALT (II) ION | Authors: | Yang, Y, Daivs, I, Matsui, T, Rubalcava, I, Liu, A. | Deposit date: | 2018-09-14 | Release date: | 2019-06-19 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.77 Å) | Cite: | Quaternary structure of alpha-amino-beta-carboxymuconate-ε-semialdehyde decarboxylase (ACMSD) controls its activity. J.Biol.Chem., 294, 2019
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6JBZ
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![BU of 6jbz by Molmil](/molmil-images/mine/6jbz) | |
6UXL
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![BU of 6uxl by Molmil](/molmil-images/mine/6uxl) | |
2GQV
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![BU of 2gqv by Molmil](/molmil-images/mine/2gqv) | |
6JC0
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![BU of 6jc0 by Molmil](/molmil-images/mine/6jc0) | |
3A4D
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![BU of 3a4d by Molmil](/molmil-images/mine/3a4d) | Crystal structure of Human Transthyretin (wild-type) | Descriptor: | GLYCEROL, SULFATE ION, Transthyretin | Authors: | Miyata, M. | Deposit date: | 2009-07-06 | Release date: | 2009-12-22 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Role of the Glutamic Acid 54 Residue in Transthyretin Stability and Thyroxine Binding Biochemistry, 2009
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7DLM
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![BU of 7dlm by Molmil](/molmil-images/mine/7dlm) | Short chain dehydrogenase (SCR) crystal structure with NADPH | Descriptor: | Carbonyl Reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | Authors: | Li, Y.H, Zhang, R.Z, Forouhar, F, Wang, C, Montelione, G.T, Szyperski, T, Xu, Y, Hunt, J.F. | Deposit date: | 2020-11-28 | Release date: | 2022-04-06 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.59 Å) | Cite: | Oligomeric interactions maintain active-site structure in a noncooperative enzyme family. Embo J., 41, 2022
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4XYK
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![BU of 4xyk by Molmil](/molmil-images/mine/4xyk) | Crystal structure of human phosphofructokinase-1 in complex with ADP, Northeast Structural Genomics Consortium Target HR9275 | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent 6-phosphofructokinase, platelet type, ... | Authors: | Forouhar, F, Webb, B.A, Szu, F.-E, Seetharaman, J, Barber, D.L, Tong, L, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2015-02-02 | Release date: | 2015-05-06 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | Structures of human phosphofructokinase-1 and atomic basis of cancer-associated mutations. Nature, 523, 2015
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6T6W
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![BU of 6t6w by Molmil](/molmil-images/mine/6t6w) | |
3A4F
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![BU of 3a4f by Molmil](/molmil-images/mine/3a4f) | Crystal Structure of Human Transthyretin (E54K) | Descriptor: | GLYCEROL, SULFATE ION, Transthyretin | Authors: | Miyata, M, Sato, T, Nakamura, T, Ikemizu, S, Yamagata, Y, Kai, H. | Deposit date: | 2009-07-06 | Release date: | 2009-12-22 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.99 Å) | Cite: | Role of the glutamic acid 54 residue in transthyretin stability and thyroxine binding Biochemistry, 49, 2010
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6TGL
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![BU of 6tgl by Molmil](/molmil-images/mine/6tgl) | |
1XA9
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![BU of 1xa9 by Molmil](/molmil-images/mine/1xa9) | Crystal structure of yellow fluorescent protein zFP538 K66M green mutant | Descriptor: | BETA-MERCAPTOETHANOL, fluorescent protein FP538 | Authors: | Remington, S.J, Wachter, R.M, Yarbrough, D.K, Branchaud, B, Anderson, D.C, Kallio, K, Lukyanov, K.A. | Deposit date: | 2004-08-25 | Release date: | 2005-02-08 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | zFP538, a yellow-fluorescent protein from Zoanthus, contains a novel three-ring chromophore. Biochemistry, 44, 2005
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7QRE
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![BU of 7qre by Molmil](/molmil-images/mine/7qre) | Structure of the hetero-tetramer complex between precursor membrane protein fragment (pr) and envelope protein (E) from tick-borne encephalitis virus | Descriptor: | ACETATE ION, Envelope protein E, Genome polyprotein, ... | Authors: | Vaney, M.C, Dellarole, M, Rey, F.A. | Deposit date: | 2022-01-11 | Release date: | 2022-05-25 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Evolution and activation mechanism of the flavivirus class II membrane-fusion machinery. Nat Commun, 13, 2022
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6MGS
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![BU of 6mgs by Molmil](/molmil-images/mine/6mgs) | Crystal structure of alpha-Amino-beta-Carboxymuconate-epsilon-Semialdehyde-Decarboxylase with Space Group of C2221 | Descriptor: | 2-amino-3-carboxymuconate 6-semialdehyde decarboxylase, COBALT (II) ION | Authors: | Yang, Y, Davis, I, Matsui, T, Rubalcava, I, Liu, A. | Deposit date: | 2018-09-14 | Release date: | 2019-06-19 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (3.131 Å) | Cite: | Quaternary structure of alpha-amino-beta-carboxymuconate-ε-semialdehyde decarboxylase (ACMSD) controls its activity. J.Biol.Chem., 294, 2019
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6T2I
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6T4E
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6T5R
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![BU of 6t5r by Molmil](/molmil-images/mine/6t5r) | |