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5BOJ

Crystal Structure of Human Transthyretin in Complex with Gemfibrozil

Summary for 5BOJ
Entry DOI10.2210/pdb5boj/pdb
Related4qxv
DescriptorTransthyretin, 5-(2,5-dimethylphenoxy)-2,2-dimethylpentanoic acid, SODIUM ION, ... (4 entities in total)
Functional Keywordstransport protein, thyroxine binding, gemfibrozil complex
Biological sourceHomo sapiens (Human)
Cellular locationSecreted: P02766
Total number of polymer chains2
Total formula weight28078.38
Authors
Begum, A.,Olofsson, A.,Sauer-Eriksson, A.E. (deposition date: 2015-05-27, release date: 2015-08-05, Last modification date: 2024-01-10)
Primary citationIakovleva, I.,Brannstrom, K.,Nilsson, L.,Gharibyan, A.L.,Begum, A.,Anan, I.,Walfridsson, M.,Sauer-Eriksson, A.E.,Olofsson, A.
Enthalpic Forces Correlate with the Selectivity of Transthyretin-Stabilizing Ligands in Human Plasma.
J.Med.Chem., 58:6507-6515, 2015
Cited by
PubMed: 26214366
DOI: 10.1021/acs.jmedchem.5b00544
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.75 Å)
Structure validation

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