3TN9
 
 | | X-ray structure of the HRV2 empty capsid (B-particle) | | Descriptor: | Protein VP1, Protein VP2, Protein VP3 | | Authors: | Garriga, D, Pickl-Herk, A, Luque, D, Wruss, J, Caston, J.R, Blaas, D, Verdaguer, N. | | Deposit date: | 2011-09-01 | | Release date: | 2012-03-28 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Insights into minor group rhinovirus uncoating: the X-ray structure of the HRV2 empty capsid.
Plos Pathog., 8, 2012
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7BG6
 | | HRV14 native particle solved by cryoEM | | Descriptor: | Genome polyprotein, RNA-octamer (5'-R(P*UP*GP*UP*UP*UP*UP*UP*A)-3') | | Authors: | Hrebik, D, Fuzik, T, Plevka, P. | | Deposit date: | 2021-01-06 | | Release date: | 2021-05-19 | | Last modified: | 2024-07-10 | | Method: | ELECTRON MICROSCOPY (2.6 Å) | | Cite: | ICAM-1 induced rearrangements of capsid and genome prime rhinovirus 14 for activation and uncoating.
Proc.Natl.Acad.Sci.USA, 118, 2021
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8K2A
 | | Cryo-EM structure of the human 55S mitoribosome with Tigecycline | | Descriptor: | 12S rRNA, 16S rRNA, 39S ribosomal protein L22, ... | | Authors: | Li, X, Wang, M, Cheng, J. | | Deposit date: | 2023-07-12 | | Release date: | 2024-07-10 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline.
Nat Commun, 15, 2024
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1AKH
 | | MAT A1/ALPHA2/DNA TERNARY COMPLEX | | Descriptor: | DNA (5'-D(*TP*AP*CP*AP*TP*GP*TP*AP*AP*AP*AP*AP*TP*TP*TP*AP*C P*AP*TP*CP*A)-3'), DNA (5'-D(*TP*AP*TP*GP*AP*TP*GP*TP*AP*AP*AP*TP*TP*TP*TP*TP*A P*CP*AP*TP*G)-3'), PROTEIN (MATING-TYPE PROTEIN A-1), ... | | Authors: | Li, T, Jin, Y, Vershon, A.K, Wolberger, C. | | Deposit date: | 1997-05-19 | | Release date: | 1998-05-20 | | Last modified: | 2023-08-02 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Crystal structure of the MATa1/MATalpha2 homeodomain heterodimer in complex with DNA containing an A-tract.
Nucleic Acids Res., 26, 1998
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4A4I
 | | Crystal structure of the human Lin28b cold shock domain | | Descriptor: | GLYCEROL, PROTEIN LIN-28 HOMOLOG B, SULFATE ION | | Authors: | Mayr, F, Schuetz, A, Doege, N, Heinemann, U. | | Deposit date: | 2011-10-14 | | Release date: | 2012-08-08 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | The Lin28 Cold-Shock Domain Remodels Pre-Let-7 Microrna.
Nucleic Acids Res., 40, 2012
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3U0J
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6B4G
 | | Crystal structure of Chaetomium thermophilum Gle1 CTD-Nup42 GBM complex | | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Nucleoporin AMO1, Nucleoporin GLE1 | | Authors: | Lin, D.H, Correia, A.R, Cai, S.W, Huber, F.M, Jette, C.A, Hoelz, A. | | Deposit date: | 2017-09-26 | | Release date: | 2018-06-20 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2.648 Å) | | Cite: | Structural and functional analysis of mRNA export regulation by the nuclear pore complex.
Nat Commun, 9, 2018
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5G5P
 | | Structure of the Saccharomyces cerevisiae TREX-2 complex | | Descriptor: | 26S PROTEASOME COMPLEX SUBUNIT SEM1, NUCLEAR MRNA EXPORT PROTEIN SAC3, NUCLEAR MRNA EXPORT PROTEIN THP1 | | Authors: | Aibara, S, Bai, X.C, Stewart, M. | | Deposit date: | 2016-05-26 | | Release date: | 2016-11-23 | | Last modified: | 2024-05-08 | | Method: | ELECTRON MICROSCOPY (5.3 Å) | | Cite: | The Sac3 Tpr-Like Region in the Saccharomyces Cerevisiae Trex-2 Complex is More Extensive But Independent of the Cid Region
J.Struct.Biol., 195, 2016
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6GZP
 | | Llama nanobody PorM_02 structure determined at room temperature by in-situ diffraction in ChipX microfluidic device | | Descriptor: | Nanobody | | Authors: | Roche, J, Gaubert, A, Desmyter, A, De Wijn, R, Sauter, C, Roussel, A. | | Deposit date: | 2018-07-04 | | Release date: | 2018-07-18 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | A simple and versatile microfluidic device for efficient biomacromolecule crystallization and structural analysis by serial crystallography.
Iucrj, 6, 2019
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4KE5
 | | HCV NS5B GT1B N316Y with GSK5852 | | Descriptor: | HCV Polymerase, [4-({[5-cyclopropyl-2-(4-fluorophenyl)-3-(methylcarbamoyl)-1-benzofuran-6-yl](methylsulfonyl)amino}methyl)-2-fluorophenyl]boronic acid | | Authors: | Williams, S.P, Kahler, K.M, Shotwell, J.B. | | Deposit date: | 2013-04-25 | | Release date: | 2013-05-15 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2.11 Å) | | Cite: | Discovery of a Potent Boronic Acid Derived Inhibitor of the HCV RNA-Dependent RNA Polymerase.
J.Med.Chem., 57, 2014
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1YVR
 | | Ro autoantigen | | Descriptor: | 60-kDa SS-A/Ro ribonucleoprotein | | Authors: | Stein, A.J, Fuchs, G, Fu, C, Wolin, S.L, Reinisch, K.M. | | Deposit date: | 2005-02-16 | | Release date: | 2005-06-07 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Structural Insights into RNA Quality Control: The Ro Autoantigen Binds Misfolded RNAs via Its Central Cavity
Cell(Cambridge,Mass.), 121, 2005
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6AE4
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4KBI
 | | HCV NS5B GT1B N316Y with CMPD 4 | | Descriptor: | 5-cyclopropyl-6-{[(7-fluoro-1-hydroxy-1,3-dihydro-2,1-benzoxaborol-5-yl)methyl](methylsulfonyl)amino}-2-(4-fluorophenyl)-N-methyl-1-benzofuran-3-carboxamide, HCV Polymerase | | Authors: | Williams, S.P, Kahler, K.M, Shotwell, J.B. | | Deposit date: | 2013-04-23 | | Release date: | 2013-05-08 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2.06 Å) | | Cite: | Discovery of a Potent Boronic Acid Derived Inhibitor of the HCV RNA-Dependent RNA Polymerase.
J.Med.Chem., 57, 2014
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3US5
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3HFO
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1OHK
 | | HUMAN DIHYDROFOLATE REDUCTASE, ORTHORHOMBIC (P21 21 21) CRYSTAL FORM | | Descriptor: | DIHYDROFOLATE REDUCTASE, N-(4-CARBOXY-4-{4-[(2,4-DIAMINO-PTERIDIN-6-YLMETHYL)-AMINO]-BENZOYLAMINO}-BUTYL)-PHTHALAMIC ACID, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | | Authors: | Cody, V, Galitsky, N, Luft, J.R, Pangborn, W. | | Deposit date: | 1997-09-17 | | Release date: | 1998-05-27 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Comparison of two independent crystal structures of human dihydrofolate reductase ternary complexes reduced with nicotinamide adenine dinucleotide phosphate and the very tight-binding inhibitor PT523.
Biochemistry, 36, 1997
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4QFC
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4QFD
 | | Co-crystal structure of compound 2 (3-(7-hydroxy-2-oxo-4-phenyl-2H-chromen-6-yl)propanoic acid) and FAD bound to human DAAO at 2.85A | | Descriptor: | 3-(7-hydroxy-2-oxo-4-phenyl-2H-chromen-6-yl)propanoic acid, D-amino-acid oxidase, FLAVIN-ADENINE DINUCLEOTIDE, ... | | Authors: | Edwards, T.E, Chun, L, Arakaki, T.L. | | Deposit date: | 2014-05-20 | | Release date: | 2014-07-16 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.85 Å) | | Cite: | Novel human D-amino acid oxidase inhibitors stabilize an active-site lid-open conformation.
Biosci.Rep., 34, 2014
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5MUW
 | | Atomic structure of P4 packaging enzyme fitted into a localized reconstruction of bacteriophage phi6 vertex | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, Packaging enzyme P4 | | Authors: | Sun, Z, El Omari, K, Sun, X, Ilca, S, Kotecha, A, Stuart, D.I, Poranen, M.M, Huiskonen, J.T. | | Deposit date: | 2017-01-14 | | Release date: | 2017-03-22 | | Last modified: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (9.1 Å) | | Cite: | Double-stranded RNA virus outer shell assembly by bona fide domain-swapping.
Nat Commun, 8, 2017
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7X7H
 | | Crystal structure of Fructose regulator/Histidine phosphocarrier protein complex from Vibrio cholerae | | Descriptor: | CALCIUM ION, Catabolite repressor/activator, HPr family phosphocarrier protein | | Authors: | Kim, M.-K, Zhang, J, Yoon, C.-K, Seok, Y.-J. | | Deposit date: | 2022-03-09 | | Release date: | 2023-03-15 | | Last modified: | 2024-05-29 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | HPr prevents FruR-mediated facilitation of RNA polymerase binding to the fru promoter in Vibrio cholerae.
Nucleic Acids Res., 51, 2023
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8R8P
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5MUV
 | | Atomic structure fitted into a localized reconstruction of bacteriophage phi6 packaging hexamer P4 | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, Packaging enzyme P4 | | Authors: | Sun, Z, El Omari, K, Sun, X, Ilca, S, Kotecha, A, Stuart, D.I, Poranen, M.M, Huiskonen, J.T. | | Deposit date: | 2017-01-14 | | Release date: | 2017-03-22 | | Last modified: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (9.1 Å) | | Cite: | Double-stranded RNA virus outer shell assembly by bona fide domain-swapping.
Nat Commun, 8, 2017
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3IZY
 | | Mammalian mitochondrial translation initiation factor 2 | | Descriptor: | Translation initiation factor IF-2, mitochondrial, tRNA-Phe | | Authors: | Yassin, A.S, Haque, E, Datta, P.P, Elmore, K, Banavali, N.K, Spremulli, L.L, Agrawal, R.K. | | Deposit date: | 2011-01-19 | | Release date: | 2011-03-23 | | Last modified: | 2024-02-21 | | Method: | ELECTRON MICROSCOPY (10.8 Å) | | Cite: | Insertion domain within mammalian mitochondrial translation initiation factor 2 serves the role of eubacterial initiation factor 1
Proc.Natl.Acad.Sci.USA, 108, 2011
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6D3L
 | | Crystal structure of unphosphorylated human PKR | | Descriptor: | Interferon-induced, double-stranded RNA-activated protein kinase | | Authors: | Erlandsen, H, Mayo, C, Robinson, V.L, Cole, J.L. | | Deposit date: | 2018-04-16 | | Release date: | 2019-07-10 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | Structural Basis of Protein Kinase R Autophosphorylation.
Biochemistry, 58, 2019
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5L7O
 | | X-ray structure of Triatoma virus empty capsid | | Descriptor: | Capsid protein | | Authors: | Sanchez-Eugenia, R. | | Deposit date: | 2016-06-03 | | Release date: | 2016-08-31 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (3.6 Å) | | Cite: | X-ray structure of Triatoma virus empty capsid: insights into the mechanism of uncoating and RNA release in dicistroviruses.
J.Gen.Virol., 97, 2016
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