PDB: 46200 resultsInfo pagesStatus searchChemie searchBIRD

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4XPC	Crystal structure of 5'- CTTATAAATTTATAAG in a host-guest complex Descriptor: 1,2-ETHANEDIOL, DNA (5'-D(*CP*TP*TP*AP*TP*AP*AP*A)-3'), DNA (5'-D(P*TP*TP*TP*AP*TP*AP*AP*G)-3'), ... Authors: Georgiadis, M.M, Singh, I. Deposit date: 2015-01-16 Release date: 2015-05-27 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.68 Å) Cite: Structural basis for a six nucleotide genetic alphabet. J. Am. Chem. Soc., 137, 2015
4XPE	Crystal structure of 5'-CTTATGGGCCCATAAG in a host-guest complex Descriptor: 1,2-ETHANEDIOL, DNA (5'-D(*CP*TP*TP*AP*TP*GP*GP*G)-3'), DNA (5'-D(P*CP*CP*CP*AP*TP*AP*AP*G)-3'), ... Authors: Georgiadis, M.M, Singh, I. Deposit date: 2015-01-16 Release date: 2015-05-27 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.78 Å) Cite: Structural basis for a six nucleotide genetic alphabet. J. Am. Chem. Soc., 137, 2015
4FMN	Structure of the C-terminal domain of the Saccharomyces cerevisiae MUTL alpha (MLH1/PMS1) heterodimer bound to a fragment of NTG2 Descriptor: 1,2-ETHANEDIOL, DNA mismatch repair protein MLH1, DNA mismatch repair protein PMS1, ... Authors: Gueneau, E, Legrand, P, Charbonnier, J.B. Deposit date: 2012-06-18 Release date: 2013-02-20 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.69 Å) Cite: Structure of the MutL alpha C-terminal domain reveals how Mlh1 contributes to Pms1 endonuclease site. Nat.Struct.Mol.Biol., 20, 2013
4YM5	Crystal structure of the human nucleosome containing 6-4PP (inside) Descriptor: 144 mer-DNA, 144-mer DNA, Histone H2A type 1-B/E, ... Authors: Osakabe, A, Tachiwana, H, Kagawa, W, Horikoshi, N, Matsumoto, S, Hasegawa, M, Matsumoto, N, Toga, T, Yamamoto, J, Hanaoka, F, Thoma, N.H, Sugasawa, K, Iwai, S, Kurumizaka, H. Deposit date: 2015-03-06 Release date: 2015-12-02 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (4.005 Å) Cite: Structural basis of pyrimidine-pyrimidone (6-4) photoproduct recognition by UV-DDB in the nucleosome Sci Rep, 5, 2015
2W57	Crystal structure of the Vibrio cholerae ferric uptake regulator (Fur) reveals structural rearrangement of the DNA-binding domains Descriptor: FERRIC UPTAKE REGULATION PROTEIN, ZINC ION Authors: Sheikh, M.A, Taylor, G.L. Deposit date: 2008-12-05 Release date: 2009-01-20 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Crystal Structure of the Vibrio Cholerae Ferric Uptake Regulator (Fur) Reveals Insights Into Metal Co-Ordination. Mol.Microbiol., 72, 2009
7BM2	Crystal structure of the DNA-binding protein RemA from Geobacillus thermodenitrificans Descriptor: Putative regulatory protein GTNG_1019, SULFATE ION Authors: Altegoer, F, Mrusek, D, Bange, G. Deposit date: 2021-01-19 Release date: 2021-08-25 Last modified: 2021-10-13 Method: X-RAY DIFFRACTION (2.29 Å) Cite: Structural and functional characterization of the bacterial biofilm activator RemA. Nat Commun, 12, 2021
8VCJ	CryoEM structure of the TnsC(1-503)-TnsD(1-318)-DNA complex in a 7:2:1 stoichiometry from E. coli Tn7 bound to ATPgS and ADP Descriptor: ADENOSINE-5'-DIPHOSPHATE, DNA, MAGNESIUM ION, ... Authors: Shen, Y, Guarne, A. Deposit date: 2023-12-14 Release date: 2024-07-31 Method: ELECTRON MICROSCOPY (3.32 Å) Cite: Assembly of the Tn7 targeting complex by a regulated stepwise process. Mol.Cell, 84, 2024
4GS3	Dimeric structure of the N-terminal domain of PriB protein from Thermoanaerobacter tencongensis solved ab initio Descriptor: Single-stranded DNA-binding protein Authors: Liebschner, D, Brzezinski, K, Dauter, M, Dauter, Z, Nowak, M, Kur, J, Olszewski, M. Deposit date: 2012-08-27 Release date: 2012-09-19 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.09 Å) Cite: Dimeric structure of the N-terminal domain of PriB protein from Thermoanaerobacter tengcongensis solved ab initio. Acta Crystallogr.,Sect.D, 68, 2012
5HOO	Crystal structure of the Mos1 Strand Transfer Complex Descriptor: MAGNESIUM ION, Mariner Mos1 transposase, Mos1 IR DNA NTS, ... Authors: Richardson, J.M, Morris, E.R. Deposit date: 2016-01-19 Release date: 2016-06-01 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (3.3 Å) Cite: A bend, flip and trap mechanism for transposon integration. Elife, 5, 2016
7LMA	Tetrahymena telomerase T3D2 structure at 3.3 Angstrom Descriptor: Telomerase La-related protein p65, Telomerase RNA, Telomerase associated protein p50, ... Authors: He, Y, Wang, Y, Liu, B, Helmling, C, Susac, L, Cheng, R, Zhou, Z.H, Feigon, J. Deposit date: 2021-02-05 Release date: 2021-05-12 Last modified: 2024-03-06 Method: ELECTRON MICROSCOPY (3.3 Å) Cite: Structures of telomerase at several steps of telomere repeat synthesis. Nature, 593, 2021
7LMB	Tetrahymena telomerase T5D5 structure at 3.8 Angstrom Descriptor: Telomerase La-related protein p65, Telomerase RNA, Telomerase associated protein p50, ... Authors: He, Y, Wang, Y, Liu, B, Helmling, C, Susac, L, Cheng, R, Zhou, Z.H, Feigon, J. Deposit date: 2021-02-05 Release date: 2021-05-12 Last modified: 2024-03-06 Method: ELECTRON MICROSCOPY (3.8 Å) Cite: Structures of telomerase at several steps of telomere repeat synthesis. Nature, 593, 2021
6ZX9	Crystal structure of SIV Vpr,fused to T4 lysozyme, isolated from moustached monkey, bound to human DDB1 and human DCAF1 (amino acid residues 1046-1396) Descriptor: DDB1- and CUL4-associated factor 1, DNA damage-binding protein 1, GLYCEROL, ... Authors: Schwefel, D, Banchenko, S. Deposit date: 2020-07-29 Release date: 2021-07-21 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.519729 Å) Cite: Structural insights into Cullin4-RING ubiquitin ligase remodelling by Vpr from simian immunodeficiency viruses. Plos Pathog., 17, 2021
5IWM	2.5A structure of GSK945237 with S.aureus DNA gyrase and DNA. Descriptor: (1R)-1-[(4-{[(6,7-dihydro[1,4]dioxino[2,3-c]pyridazin-3-yl)methyl]amino}piperidin-1-yl)methyl]-9-fluoro-1,2-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-4-one, DNA (5'-D(*AP*GP*CP*CP*GP*TP*AP*GP*GP*TP*TP*CP*AP*CP*CP*GP*CP*AP*CP*A)-3'), DNA (5'-D(*TP*GP*TP*GP*CP*GP*GP*TP*GP*AP*AP*CP*CP*TP*AP*CP*GP*GP*CP*T)-3'), ... Authors: Bax, B.D, Miles, T.J. Deposit date: 2016-03-22 Release date: 2016-05-25 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Novel tricyclics (e.g., GSK945237) as potent inhibitors of bacterial type IIA topoisomerases. Bioorg.Med.Chem.Lett., 26, 2016
8W0E	Cryo-EM structure of a human MCM2-7 single hexamer on dsDNA Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, DNA (25-MER), ... Authors: Hunker, O, Yang, R, Bleichert, F. Deposit date: 2024-02-13 Release date: 2024-10-02 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: Multiple pathways for licensing human replication origins To Be Published
8W0F	Cryo-EM structure of a human MCM2-7 double hexamer on dsDNA Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, DNA (47-MER), ... Authors: Hunker, O, Yang, R, Bleichert, F. Deposit date: 2024-02-13 Release date: 2024-10-02 Method: ELECTRON MICROSCOPY (2.8 Å) Cite: Multiple pathways for licensing human replication origins To Be Published
5ZBA	Crystal structure of Rtt109-Asf1-H3-H4-CoA complex Descriptor: COENZYME A, DNA damage response protein Rtt109, putative, ... Authors: Zhang, L, Serra-Cardona, A, Zhou, H, Wang, M, Yang, N, Zhang, Z, Xu, R.M. Deposit date: 2018-02-10 Release date: 2018-07-25 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (3.5 Å) Cite: Multisite Substrate Recognition in Asf1-Dependent Acetylation of Histone H3 K56 by Rtt109. Cell, 174, 2018
1I6H	RNA POLYMERASE II ELONGATION COMPLEX Descriptor: 5'-D(P*AP*AP*AP*TP*GP*CP*CP*TP*GP*GP*TP*CP*T)-3', 5'-R(P*GP*AP*CP*CP*AP*GP*GP*CP*A)-3', DNA-DIRECTED RNA POLYMERASE II 13.6KD POLYPEPTIDE, ... Authors: Gnatt, A.L, Cramer, P, Kornberg, R.D. Deposit date: 2001-03-02 Release date: 2001-04-23 Last modified: 2023-08-09 Method: X-RAY DIFFRACTION (3.3 Å) Cite: Structural basis of transcription: an RNA polymerase II elongation complex at 3.3 A resolution. Science, 292, 2001
5ZBB	Crystal structure of Rtt109-Asf1-H3-H4 complex Descriptor: DI(HYDROXYETHYL)ETHER, DNA damage response protein Rtt109, putative, ... Authors: Zhang, L, Serra-Cardona, A, Zhou, H, Wang, M, Yang, N, Zhang, Z, Xu, R.M. Deposit date: 2018-02-10 Release date: 2018-07-25 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (3.6 Å) Cite: Multisite Substrate Recognition in Asf1-Dependent Acetylation of Histone H3 K56 by Rtt109. Cell, 174, 2018
1PVR	BASIS FOR A SWITCH IN SUBSTRATE SPECIFICITY: CRYSTAL STRUCTURE OF SELECTED VARIANT OF CRE SITE-SPECIFIC RECOMBINASE, LNSGG BOUND TO THE LOXP (WILDTYPE) RECOGNITION SITE Descriptor: 34-MER, Recombinase CRE Authors: Baldwin, E.P, Martin, S.S, Abel, J, Gelato, K.A, Kim, H, Schultz, P.G, Santoro, S.W. Deposit date: 2003-06-28 Release date: 2004-02-17 Last modified: 2023-08-16 Method: X-RAY DIFFRACTION (2.65 Å) Cite: A specificity switch in selected cre recombinase variants is mediated by macromolecular plasticity and water. Chem.Biol., 10, 2003
1PVP	BASIS FOR A SWITCH IN SUBSTRATE SPECIFICITY: CRYSTAL STRUCTURE OF SELECTED VARIANT OF CRE SITE-SPECIFIC RECOMBINASE, ALSHG BOUND TO THE ENGINEERED RECOGNITION SITE LOXM7 Descriptor: 34-MER, Recombinase cre Authors: Baldwin, E.P, Martin, S.S, Abel, J, Gelato, K.A, Kim, H, Schultz, P.G, Santoro, S.W. Deposit date: 2003-06-28 Release date: 2004-02-17 Last modified: 2023-08-16 Method: X-RAY DIFFRACTION (2.35 Å) Cite: A specificity switch in selected cre recombinase variants is mediated by macromolecular plasticity and water. Chem.Biol., 10, 2003
1MYK	CRYSTAL STRUCTURE, FOLDING, AND OPERATOR BINDING OF THE HYPERSTABLE ARC REPRESSOR MUTANT PL8 Descriptor: ARC REPRESSOR Authors: Schildbach, J.F, Milla, M.E, Jeffrey, P.D, Raumann, B.E, Sauer, R.T. Deposit date: 1994-10-12 Release date: 1995-01-26 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Crystal structure, folding, and operator binding of the hyperstable Arc repressor mutant PL8. Biochemistry, 34, 1995
2BJ8	NIKR IN CLOSED CONFORMATION AND NICKEL BOUND TO HIGH and LOW-AFFINITY SITES Descriptor: 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CHLORIDE ION, ... Authors: Tahirov, T.H. Deposit date: 2005-01-31 Release date: 2005-04-08 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Structure of Pyrococcus Horikoshii Nikr: Nickel Sensing and Implications for the Regulation of DNA Recognition J.Mol.Biol., 348, 2005
1EYF	REFINED STRUCTURE OF THE DNA METHYL PHOSPHOTRIESTER REPAIR DOMAIN OF E. COLI ADA Descriptor: ADA REGULATORY PROTEIN, ZINC ION Authors: Lin, Y, Dotsch, V, Wintner, T, Peariso, K, Myers, L.C, Penner-Hahn, J.E, Verdine, G.L, Wagner, G. Deposit date: 2000-05-06 Release date: 2003-09-09 Last modified: 2024-05-22 Method: SOLUTION NMR Cite: Structural basis for the functional switch of the E. coli Ada protein Biochemistry, 40, 2001
6URS	Sleeping Beauty transposase PAI subdomain mutant - H19Y Descriptor: Sleeping Beauty transposase PAI subdomain Authors: Nesmelova, I.V, Leighton, G.O, Yan, C, Lustig, J, Corona, R.I, Guo, J.T, Ivics, Z. Deposit date: 2019-10-24 Release date: 2020-10-28 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: H19Y mutation in the primary DNA-recognition subdomain of the Sleeping Beauty transposase improves structural stability, transposon DNA-binding and transposition To Be Published
2BJ7	NIKR IN CLOSED CONFORMATION AND NICKEL BOUND TO HIGH-AFFINITY SITES Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, NICKEL (II) ION, ... Authors: Tahirov, T.H. Deposit date: 2005-01-31 Release date: 2005-04-08 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Structure of Pyrococcus Horikoshii Nikr: Nickel Sensing and Implications for the Regulation of DNA Recognition J.Mol.Biol., 348, 2005

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