4FMN
Structure of the C-terminal domain of the Saccharomyces cerevisiae MUTL alpha (MLH1/PMS1) heterodimer bound to a fragment of NTG2
Summary for 4FMN
Entry DOI | 10.2210/pdb4fmn/pdb |
Related | 4E4W 4FMO |
Descriptor | DNA mismatch repair protein MLH1, DNA mismatch repair protein PMS1, DNA repair peptide, ... (7 entities in total) |
Functional Keywords | mismatch repair, mutl, endonuclease, zn-binding protein, dna damage, dna repair, hydrolase |
Biological source | Saccharomyces cerevisiae (yeast) More |
Cellular location | Nucleus: P38920 P14242 Q08214 |
Total number of polymer chains | 3 |
Total formula weight | 63236.33 |
Authors | Gueneau, E.,Legrand, P.,Charbonnier, J.B. (deposition date: 2012-06-18, release date: 2013-02-20, Last modification date: 2023-09-13) |
Primary citation | Gueneau, E.,Dherin, C.,Legrand, P.,Tellier-Lebegue, C.,Gilquin, B.,Bonnesoeur, P.,Londino, F.,Quemener, C.,Le Du, M.H.,Marquez, J.A.,Moutiez, M.,Gondry, M.,Boiteux, S.,Charbonnier, J.B. Structure of the MutL alpha C-terminal domain reveals how Mlh1 contributes to Pms1 endonuclease site. Nat.Struct.Mol.Biol., 20:461-468, 2013 Cited by PubMed: 23435383DOI: 10.1038/nsmb.2511 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.69 Å) |
Structure validation
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