4FMN
Structure of the C-terminal domain of the Saccharomyces cerevisiae MUTL alpha (MLH1/PMS1) heterodimer bound to a fragment of NTG2
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | DNA mismatch repair protein MLH1 | polymer | 288 | 33239.1 | 1 | UniProt (P38920) Pfam (PF16413) In PDB | Saccharomyces cerevisiae (yeast) | MutL protein homolog 1, Post meiotic segregation protein 2 |
2 | B | DNA mismatch repair protein PMS1 | polymer | 240 | 27948.2 | 1 | UniProt (P14242) Pfam (PF08676) In PDB | Saccharomyces cerevisiae (yeast) | Postmeiotic segregation protein 1 |
3 | C | DNA repair peptide | polymer | 9 | 1085.3 | 1 | UniProt (Q08214) In PDB | Saccharomyces cerevisiae | Ntg2 (DNA N-glycosylase and apurinic or apyrimidinic lyase) |
4 | A | GLYCEROL | non-polymer | 92.1 | 5 | Chemie (GOL) | |||
5 | A, B | 1,2-ETHANEDIOL | non-polymer | 62.1 | 6 | Chemie (EDO) | |||
6 | B | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
7 | water | water | 18.0 | 131 | Chemie (HOH) |
Sequence modifications
A: 485 - 769 (UniProt: P38920)
B: 635 - 873 (UniProt: P14242)
C: 22 - 29 (UniProt: Q08214)
PDB | External Database | Details |
---|---|---|
Gly 482 | - | expression tag |
Ala 483 | - | expression tag |
Met 484 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Gly 634 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Ace 21 | - | acetylation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 62272.6 | |
Non-Polymers* | Number of molecules | 13 |
Total formula weight | 963.7 | |
All* | Total formula weight | 63236.3 |