6RYU
 
 | | Nucleosome-CHD4 complex structure (two CHD4 copies) | | Descriptor: | Chromodomain-helicase-DNA-binding protein 4,CHD4,Chromodomain-helicase-DNA-binding protein 4, DNA (149-MER), Histone H2A type 1, ... | | Authors: | Farnung, L, Ochmann, M, Cramer, P. | | Deposit date: | 2019-06-12 | | Release date: | 2020-07-15 | | Last modified: | 2024-05-22 | | Method: | ELECTRON MICROSCOPY (4 Å) | | Cite: | Nucleosome-CHD4 chromatin remodeller structure maps human disease mutations.
Elife, 9, 2020
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6J4Z
 | | RNA polymerase II elongation complex bound with Spt4/5 and foreign DNA, stalled at SHL(-1) of the nucleosome | | Descriptor: | DNA (198-MER), DNA (42-MER), DNA-directed RNA polymerase subunit, ... | | Authors: | Ehara, H, Kujirai, T, Fujino, Y, Shirouzu, M, Kurumizaka, H, Sekine, S. | | Deposit date: | 2019-01-10 | | Release date: | 2019-02-20 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (4.1 Å) | | Cite: | Structural insight into nucleosome transcription by RNA polymerase II with elongation factors.
Science, 363, 2019
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7BXT
 | | The cryo-EM structure of CENP-A nucleosome in complex with CENP-C peptide and CENP-N N-terminal domain | | Descriptor: | CENP-C, DNA (145-mer), Histone H2A type 1-B/E, ... | | Authors: | Ariyoshi, M, Makino, F, Fukagawa, T. | | Deposit date: | 2020-04-20 | | Release date: | 2021-02-10 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (4.2 Å) | | Cite: | Cryo-EM structure of the CENP-A nucleosome in complex with phosphorylated CENP-C.
Embo J., 40, 2021
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9CG9
 | | Cryo-EM structure of an HMGB1 box bound to nucleosome at SHL-2 | | Descriptor: | High mobility group protein B1, Histone H2A type 1, Histone H2B, ... | | Authors: | Chio, U.S, Saunders, H.S, Narlikar, G.J, Cheng, Y. | | Deposit date: | 2024-06-28 | | Release date: | 2025-07-02 | | Method: | ELECTRON MICROSCOPY (2.94 Å) | | Cite: | Competition between HMGB1 and H1 on nucleosomes tunes dynamics within condensed chromatin
To Be Published
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6J51
 | | RNA polymerase II elongation complex bound with Spt4/5 and foreign DNA, stalled at SHL(-1) of the nucleosome, weak Elf1 (+1 position) | | Descriptor: | DNA (198-MER), DNA (36-MER), DNA-directed RNA polymerase subunit, ... | | Authors: | Ehara, H, Kujirai, T, Fujino, Y, Shirouzu, M, Kurumizaka, H, Sekine, S. | | Deposit date: | 2019-01-10 | | Release date: | 2019-02-20 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (4.2 Å) | | Cite: | Structural insight into nucleosome transcription by RNA polymerase II with elongation factors.
Science, 363, 2019
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6J4Y
 | | RNA polymerase II elongation complex bound with Elf1 and Spt4/5, stalled at SHL(-1) of the nucleosome (+1B) | | Descriptor: | DNA (198-MER), DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, ... | | Authors: | Ehara, H, Kujirai, T, Fujino, Y, Shirouzu, M, Kurumizaka, H, Sekine, S. | | Deposit date: | 2019-01-10 | | Release date: | 2019-02-20 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (4.3 Å) | | Cite: | Structural insight into nucleosome transcription by RNA polymerase II with elongation factors.
Science, 363, 2019
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5B40
 | | The nucleosome structure containing H2B-K120 and H4-K31 monoubiquitinations | | Descriptor: | DNA (146-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ... | | Authors: | Machida, S, Sekine, S, Nishiyama, Y, Horikoshi, N, Kurumizaka, H. | | Deposit date: | 2016-03-22 | | Release date: | 2016-06-22 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (3.33 Å) | | Cite: | Monoubiquitination of histones H2B and H4 changes the nucleosome stability without affecting the nucleosome structure
To Be Published
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1XQH
 | | Crystal structure of a ternary complex of the methyltransferase SET9 (also known as SET7/9) with a P53 peptide and SAH | | Descriptor: | 9-mer peptide from tumor protein p53, Histone-lysine N-methyltransferase, H3 lysine-4 specific, ... | | Authors: | Chuikov, S, Kurash, J.K, Wilson, J.R, Xiao, B, Justin, N, Ivanov, G.S, McKinney, K, Tempst, P, Prives, C, Gamblin, S.J, Barlev, N.A, Reinberg, D. | | Deposit date: | 2004-10-12 | | Release date: | 2004-11-23 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | Regulation of p53 activity through lysine methylation
Nature, 432, 2004
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6UXW
 | | SWI/SNF nucleosome complex with ADP-BeFx | | Descriptor: | 601 sequence bottom strand, 601 sequence top strand, ADENOSINE-5'-DIPHOSPHATE, ... | | Authors: | He, Y, Han, Y. | | Deposit date: | 2019-11-08 | | Release date: | 2020-03-18 | | Last modified: | 2025-05-21 | | Method: | ELECTRON MICROSCOPY (8.96 Å) | | Cite: | Cryo-EM structure of SWI/SNF complex bound to a nucleosome.
Nature, 579, 2020
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7QRD
 | | Crystal structure of mouse CARM1 in complex with histone H3_10-25 | | Descriptor: | (2~{R},3~{R},4~{S},5~{R})-2-(6-aminopurin-9-yl)-5-[(~{E})-prop-1-enyl]oxolane-3,4-diol, 1,2-ETHANEDIOL, Histone-arginine methyltransferase CARM1, ... | | Authors: | Marechal, N, Cura, V, Troffer-Charlier, N, Bonnefond, L, Cavarelli, J. | | Deposit date: | 2022-01-11 | | Release date: | 2022-12-28 | | Last modified: | 2024-10-09 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | CARM1 Transition State Mimics
To Be Published
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2RFI
 | | Crystal structure of catalytic domain of human euchromatic histone methyltransferase 1 in complex with SAH and dimethylated H3K9 peptide | | Descriptor: | Histone H3, Histone-lysine N-methyltransferase, H3 lysine-9 specific 5, ... | | Authors: | Min, J, Wu, H, Loppnau, P, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Plotnikov, A.N, Structural Genomics Consortium (SGC) | | Deposit date: | 2007-09-30 | | Release date: | 2007-10-23 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.59 Å) | | Cite: | Structural biology of human H3K9 methyltransferases
Plos One, 5, 2010
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2CU9
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5XMY
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4UBD
 | | Crystal structure of a neutralizing human monoclonal antibody with 1968 H3 HA | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, ... | | Authors: | Shore, D.A, Yang, H, Cho, M, Donis, R.O, Stevens, J. | | Deposit date: | 2014-08-12 | | Release date: | 2015-06-24 | | Last modified: | 2024-11-13 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | A potent broad-spectrum protective human monoclonal antibody crosslinking two haemagglutinin monomers of influenza A virus.
Nat Commun, 6, 2015
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5Y20
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7M1X
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5X0X
 | | Complex of Snf2-Nucleosome complex with Snf2 bound to position +6 of the nucleosome | | Descriptor: | DNA (167-MER), Histone H2A, Histone H2B 1.1, ... | | Authors: | Li, M, Liu, X, Xia, X, Chen, Z, Li, X. | | Deposit date: | 2017-01-23 | | Release date: | 2017-04-19 | | Last modified: | 2025-07-02 | | Method: | ELECTRON MICROSCOPY (3.97 Å) | | Cite: | Mechanism of chromatin remodelling revealed by the Snf2-nucleosome structure.
Nature, 544, 2017
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5X0Y
 | | Complex of Snf2-Nucleosome complex with Snf2 bound to SHL2 of the nucleosome | | Descriptor: | DNA (167-MER), Histone H2A, Histone H2B 1.1, ... | | Authors: | Li, M, Liu, X, Xia, X, Chen, Z, Li, X. | | Deposit date: | 2017-01-23 | | Release date: | 2017-04-19 | | Last modified: | 2025-07-02 | | Method: | ELECTRON MICROSCOPY (4.69 Å) | | Cite: | Mechanism of chromatin remodelling revealed by the Snf2-nucleosome structure.
Nature, 544, 2017
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7LKA
 | | Crystal structure of SARS-CoV-2 RBD-targeting antibody COV107-23 | | Descriptor: | ACETATE ION, COV107-23 heavy chain, COV107-23 light chain | | Authors: | Yuan, M, Zhu, X, Wilson, I.A, Wu, N.C. | | Deposit date: | 2021-02-02 | | Release date: | 2021-02-10 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (1.981 Å) | | Cite: | Sequence signatures of two public antibody clonotypes that bind SARS-CoV-2 receptor binding domain.
Nat Commun, 12, 2021
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7Y8R
 | | The nucleosome-bound human PBAF complex | | Descriptor: | ACTB protein (Fragment), ADENOSINE-5'-DIPHOSPHATE, AT-rich interactive domain-containing protein 2, ... | | Authors: | Wang, L, Yu, J, Yu, Z, Wang, Q, He, S, Xu, Y. | | Deposit date: | 2022-06-24 | | Release date: | 2022-12-07 | | Last modified: | 2024-07-03 | | Method: | ELECTRON MICROSCOPY (4.4 Å) | | Cite: | Structure of nucleosome-bound human PBAF complex.
Nat Commun, 13, 2022
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7XFN
 | | Structure of nucleosome-DI complex (-55I, Apo state) | | Descriptor: | DNA (152-MER), Histone H2A type 1, Histone H2B 1.1, ... | | Authors: | Zheng, L, Tsai, B, Gao, N. | | Deposit date: | 2022-04-01 | | Release date: | 2023-04-19 | | Last modified: | 2025-07-02 | | Method: | ELECTRON MICROSCOPY (2.8 Å) | | Cite: | Structural and mechanistic insights into the DNA glycosylase AAG-mediated base excision in nucleosome.
Cell Discov, 9, 2023
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7XFI
 | | Structure of nucleosome-DI complex (-50I, Apo state) | | Descriptor: | DNA (152-MER), Histone H2A type 1, Histone H2B 1.1, ... | | Authors: | Zheng, L, Tsai, B, Gao, N. | | Deposit date: | 2022-04-01 | | Release date: | 2023-04-19 | | Last modified: | 2025-06-25 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Structural and mechanistic insights into the DNA glycosylase AAG-mediated base excision in nucleosome.
Cell Discov, 9, 2023
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7XFH
 | | Structure of nucleosome-AAG complex (A-30I, post-catalytic state) | | Descriptor: | DNA (152-MER), DNA-3-methyladenine glycosylase, Histone H2A type 1, ... | | Authors: | Zheng, L, Tsai, B, Gao, N. | | Deposit date: | 2022-04-01 | | Release date: | 2023-04-19 | | Last modified: | 2025-06-25 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Structural and mechanistic insights into the DNA glycosylase AAG-mediated base excision in nucleosome.
Cell Discov, 9, 2023
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7XFM
 | | Structure of nucleosome-AAG complex (A-53I, post-catalytic state) | | Descriptor: | DNA (152-MER), DNA-3-methyladenine glycosylase, Histone H2A type 1, ... | | Authors: | Zheng, L, Tsai, B, Gao, N. | | Deposit date: | 2022-04-01 | | Release date: | 2023-04-19 | | Last modified: | 2025-06-25 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Structural and mechanistic insights into the DNA glycosylase AAG-mediated base excision in nucleosome.
Cell Discov, 9, 2023
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7XFC
 | | Structure of nucleosome-DI complex (-30I, Apo state) | | Descriptor: | DNA (152-MER), Histone H2A type 1, Histone H2B 1.1, ... | | Authors: | Zheng, L, Tsai, B, Gao, N. | | Deposit date: | 2022-04-01 | | Release date: | 2023-04-19 | | Last modified: | 2025-07-02 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Structural and mechanistic insights into the DNA glycosylase AAG-mediated base excision in nucleosome.
Cell Discov, 9, 2023
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