4D5L
 
 | | Cryo-EM structures of ribosomal 80S complexes with termination factors and cricket paralysis virus IRES reveal the IRES in the translocated state | | Descriptor: | 18S RRNA 2, 40S RIBOSOMAL PROTEIN ES1, 40S RIBOSOMAL PROTEIN ES10, ... | | Authors: | Muhs, M, Hilal, T, Mielke, T, Skabkin, M.A, Sanbonmatsu, K.Y, Pestova, T.V, Spahn, C.M.T. | | Deposit date: | 2014-11-05 | | Release date: | 2015-02-04 | | Last modified: | 2017-08-23 | | Method: | ELECTRON MICROSCOPY (9 Å) | | Cite: | Cryo-Em of Ribosomal 80S Complexes with Termination Factors Reveals the Translocated Cricket Paralysis Virus Ires.
Mol.Cell, 57, 2015
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4PX8
 | | Structure of P. vulgaris HigB toxin | | Descriptor: | CHLORIDE ION, Killer protein | | Authors: | Schureck, M.A, Dunkle, J.A, Maehigashi, T, Dunham, C.M. | | Deposit date: | 2014-03-22 | | Release date: | 2015-10-21 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (1.25 Å) | | Cite: | Defining the mRNA recognition signature of a bacterial toxin protein.
Proc.Natl.Acad.Sci.USA, 112, 2015
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5U5Q
 | | 12 Subunit RNA Polymerase II at Room Temperature collected using SFX | | Descriptor: | DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... | | Authors: | Bushnell, D.A, Oberthur, D, Mariani, V, Yefanov, O, Tolstikova, A, Barty, A. | | Deposit date: | 2016-12-07 | | Release date: | 2017-03-29 | | Last modified: | 2019-11-27 | | Method: | X-RAY DIFFRACTION (3.8 Å) | | Cite: | Double-flow focused liquid injector for efficient serial femtosecond crystallography.
Sci Rep, 7, 2017
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8EUI
 | | Ytm1 associated nascent 60S ribosome (-fkbp39) State 3 | | Descriptor: | 60S ribosomal protein L10-A, 60S ribosomal protein L11-A, 60S ribosomal protein L13, ... | | Authors: | Zhou, X, Bilokapic, S, Deshmukh, A.A, Halic, M. | | Deposit date: | 2022-10-18 | | Release date: | 2022-11-30 | | Last modified: | 2024-06-19 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Chromatin localization of nucleophosmin organizes ribosome biogenesis.
Mol.Cell, 82, 2022
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8EUG
 | | Ytm1 associated nascent 60S ribosome State 3 | | Descriptor: | 60S ribosomal protein L10-A, 60S ribosomal protein L11-A, 60S ribosomal protein L13, ... | | Authors: | Zhou, X, Bilokapic, S, Deshmukh, A.A, Halic, M. | | Deposit date: | 2022-10-18 | | Release date: | 2022-11-30 | | Last modified: | 2024-06-19 | | Method: | ELECTRON MICROSCOPY (2.8 Å) | | Cite: | Chromatin localization of nucleophosmin organizes ribosome biogenesis.
Mol.Cell, 82, 2022
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8C91
 | | Cryo-EM captures early ribosome assembly in action | | Descriptor: | 23S rRNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ... | | Authors: | Lauer, S, Nikolay, R, Qin, B. | | Deposit date: | 2023-01-21 | | Release date: | 2023-04-05 | | Method: | ELECTRON MICROSCOPY (4.19 Å) | | Cite: | Cryo-EM captures early ribosome assembly in action.
Nat Commun, 14, 2023
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8C93
 | | Cryo-EM captures early ribosome assembly in action | | Descriptor: | 23S rRNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ... | | Authors: | Lauer, S, Nikolay, R, Qin, B. | | Deposit date: | 2023-01-21 | | Release date: | 2023-04-05 | | Method: | ELECTRON MICROSCOPY (4.17 Å) | | Cite: | Cryo-EM captures early ribosome assembly in action.
Nat Commun, 14, 2023
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8C99
 | | Cryo-EM captures early ribosome assembly in action | | Descriptor: | 23S rRNA, 50S ribosomal protein L13, 50S ribosomal protein L15, ... | | Authors: | Nikolay, R, Qin, B, Lauer, S. | | Deposit date: | 2023-01-21 | | Release date: | 2023-04-05 | | Last modified: | 2023-04-12 | | Method: | ELECTRON MICROSCOPY (3.29 Å) | | Cite: | Cryo-EM captures early ribosome assembly in action.
Nat Commun, 14, 2023
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8C92
 | | Cryo-EM captures early ribosome assembly in action | | Descriptor: | 23S rRNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ... | | Authors: | Lauer, S, Nikolay, R, Qin, B. | | Deposit date: | 2023-01-21 | | Release date: | 2023-04-05 | | Method: | ELECTRON MICROSCOPY (3.79 Å) | | Cite: | Cryo-EM captures early ribosome assembly in action.
Nat Commun, 14, 2023
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8C96
 | | Cryo-EM captures early ribosome assembly in action | | Descriptor: | 23S rRNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ... | | Authors: | Lauer, S, Nikolay, R, Qin, B. | | Deposit date: | 2023-01-21 | | Release date: | 2023-04-05 | | Method: | ELECTRON MICROSCOPY (4.43 Å) | | Cite: | Cryo-EM captures early ribosome assembly in action.
Nat Commun, 14, 2023
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8C98
 | | Cryo-EM captures early ribosome assembly in action | | Descriptor: | 23S rRNA, 50S ribosomal protein L13, 50S ribosomal protein L15, ... | | Authors: | Lauer, S, Nikolay, R, Qin, B. | | Deposit date: | 2023-01-21 | | Release date: | 2023-04-05 | | Method: | ELECTRON MICROSCOPY (3.66 Å) | | Cite: | Cryo-EM captures early ribosome assembly in action.
Nat Commun, 14, 2023
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8UMU
 | | Atomic model of the human CTF18-RFC-PCNA binary complex in the four-subunit binding state (state 3) | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Chromosome transmission fidelity protein 18 homolog, MAGNESIUM ION, ... | | Authors: | Wang, F, He, Q, Li, H. | | Deposit date: | 2023-10-18 | | Release date: | 2024-05-08 | | Last modified: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (3.16 Å) | | Cite: | Cryo-EM reveals a nearly complete PCNA loading process and unique features of the human alternative clamp loader CTF18-RFC.
Proc.Natl.Acad.Sci.USA, 121, 2024
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8UMT
 | | Atomic model of the human CTF18-RFC-PCNA binary complex in the three-subunit binding state (state 2) | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Chromosome transmission fidelity protein 18 homolog, MAGNESIUM ION, ... | | Authors: | Wang, F, He, Q, Li, H. | | Deposit date: | 2023-10-18 | | Release date: | 2024-05-08 | | Last modified: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (3.33 Å) | | Cite: | Cryo-EM reveals a nearly complete PCNA loading process and unique features of the human alternative clamp loader CTF18-RFC.
Proc.Natl.Acad.Sci.USA, 121, 2024
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7N84
 | | Double nuclear outer ring from the isolated yeast NPC | | Descriptor: | Nucleoporin 145c, Nucleoporin NUP120, Nucleoporin NUP133, ... | | Authors: | Akey, C.W, Rout, M.P, Ouch, C, Echevarria, I, Fernandez-Martinez, J, Nudelman, I. | | Deposit date: | 2021-06-13 | | Release date: | 2022-01-26 | | Last modified: | 2024-06-05 | | Method: | ELECTRON MICROSCOPY (11.6 Å) | | Cite: | Comprehensive structure and functional adaptations of the yeast nuclear pore complex.
Cell, 185, 2022
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5M3H
 | | Bat influenza A/H17N10 polymerase bound to four heptad repeats of serine 5 phosphorylated Pol II CTD | | Descriptor: | PHOSPHATE ION, Polymerase acidic protein, Polymerase basic protein 2, ... | | Authors: | Lukarska, M, Pflug, A, Cusack, S. | | Deposit date: | 2016-10-14 | | Release date: | 2016-12-21 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structural basis of an essential interaction between influenza polymerase and Pol II CTD.
Nature, 541, 2017
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5EWR
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6HIX
 | | Cryo-EM structure of the Trypanosoma brucei mitochondrial ribosome - This entry contains the large mitoribosomal subunit | | Descriptor: | 12S rRNA, 50S ribosomal protein L13, putative, ... | | Authors: | Ramrath, D.J.F, Niemann, M, Leibundgut, M, Bieri, P, Prange, C, Horn, K, Leitner, A, Boehringer, D, Schneider, A, Ban, N. | | Deposit date: | 2018-08-31 | | Release date: | 2018-09-26 | | Last modified: | 2019-02-06 | | Method: | ELECTRON MICROSCOPY (3.39 Å) | | Cite: | Evolutionary shift toward protein-based architecture in trypanosomal mitochondrial ribosomes.
Science, 362, 2018
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7AZY
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5M3J
 | | Influenza B polymerase bound to four heptad repeats of serine 5 phosphorylated Pol II CTD | | Descriptor: | DNA-directed RNA polymerase subunit, Polymerase acidic protein, Polymerase basic protein 2, ... | | Authors: | Lukarska, M, Pflug, A, Cusack, S. | | Deposit date: | 2016-10-14 | | Release date: | 2016-12-21 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | Structural basis of an essential interaction between influenza polymerase and Pol II CTD.
Nature, 541, 2017
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5YU6
 | | CRYSTAL STRUCTURE OF EXPORTIN-5:RANGTP COMPLEX | | Descriptor: | 13-mer peptide, Exportin-5, GTP-binding nuclear protein Ran, ... | | Authors: | Yamazawa, R, Jiko, C, Lee, S.J, Yamashita, E. | | Deposit date: | 2017-11-20 | | Release date: | 2018-08-29 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.997 Å) | | Cite: | Structural Basis for Selective Binding of Export Cargoes by Exportin-5
Structure, 26, 2018
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8IT9
 | | Co-crystal structure of FTO bound to 22 | | Descriptor: | 2-OXOGLUTARIC ACID, 2-[(2,6-diethyl-4-pyridin-4-yl-phenyl)amino]-6-(1,4-oxazepan-4-ylmethyl)benzoic acid, Alpha-ketoglutarate-dependent dioxygenase FTO | | Authors: | Yang, C.-G, Gan, J.H. | | Deposit date: | 2023-03-22 | | Release date: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.14 Å) | | Cite: | Rational Design of RNA Demethylase FTO Inhibitors with Enhanced Antileukemia Drug-Like Properties.
J.Med.Chem., 66, 2023
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1NKW
 | | Crystal Structure Of The Large Ribosomal Subunit From Deinococcus Radiodurans | | Descriptor: | 23S ribosomal RNA, 50S ribosomal protein L11, 50S ribosomal protein L13, ... | | Authors: | Harms, J.M, Schluenzen, F, Zarivach, R, Bashan, A, Gat, S, Agmon, I, Bartels, H, Franceschi, F, Yonath, A. | | Deposit date: | 2003-01-05 | | Release date: | 2003-02-11 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | High resolution structure of the large ribosomal subunit from a mesophilic eubacterium
Cell(Cambridge,Mass.), 107, 2001
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5AA0
 | | Complex of Thermous thermophilus ribosome (A-and P-site tRNA) bound to BipA-GDPCP | | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 3'-amino-3'-deoxyadenosine 5'-(dihydrogen phosphate), ... | | Authors: | Kumar, V, Chen, Y, Ahmed, T, Tan, J, Ero, R, Bhushan, S, Gao, Y.-G. | | Deposit date: | 2015-07-23 | | Release date: | 2015-10-14 | | Last modified: | 2019-12-18 | | Method: | ELECTRON MICROSCOPY (5 Å) | | Cite: | Structure of Bipa in GTP Form Bound to the Ratcheted Ribosome.
Proc.Natl.Acad.Sci.USA, 112, 2015
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8Q63
 | | Cryo-EM structure of IC8', a second state of yeast mitochondrial RNA polymerase transcription initiation complex with 8-mer RNA, pppGpGpUpApApApUpG | | Descriptor: | DNA-directed RNA polymerase, mitochondrial, GUANOSINE-5'-TRIPHOSPHATE, ... | | Authors: | Goovaerts, Q, Shen, J, Patel, S.S, Das, K. | | Deposit date: | 2023-08-10 | | Release date: | 2023-08-30 | | Last modified: | 2023-11-01 | | Method: | ELECTRON MICROSCOPY (3.68 Å) | | Cite: | Structures illustrate step-by-step mitochondrial transcription initiation.
Nature, 622, 2023
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8VT7
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