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5EDK
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BU of 5edk by Molmil
Crystal structure of prothrombin deletion mutant residues 146-167 ( Form II ).
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, MAGNESIUM ION, ...
Authors:Pozzi, N, Chen, Z, Di Cera, E.
Deposit date:2015-10-21
Release date:2016-01-20
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (3.214 Å)
Cite:How the Linker Connecting the Two Kringles Influences Activation and Conformational Plasticity of Prothrombin.
J.Biol.Chem., 291, 2016
8BQ6
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BU of 8bq6 by Molmil
Cryo-EM structure of the Arabidopsis thaliana I+III2 supercomplex (Complete conformation 2 composition)
Descriptor: 2,3-DIMETHOXY-5-METHYL-6-(3,11,15,19-TETRAMETHYL-EICOSA-2,6,10,14,18-PENTAENYL)-[1,4]BENZOQUINONE, AT3G07480.1, Acyl carrier protein 1, ...
Authors:Klusch, N, Kuehlbrandt, W.
Deposit date:2022-11-18
Release date:2023-05-10
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Cryo-EM structure of the respiratory I + III 2 supercomplex from Arabidopsis thaliana at 2 angstrom resolution.
Nat.Plants, 9, 2023
6OV3
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BU of 6ov3 by Molmil
Crystal structure of human claudin-9 in complex with Clostridium perfringens entertoxin C-terminal domain in open form
Descriptor: Claudin-9, Heat-labile enterotoxin B chain
Authors:Vecchio, A.J, Stroud, R.M.
Deposit date:2019-05-06
Release date:2019-09-04
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.25 Å)
Cite:Claudin-9 structures reveal mechanism for toxin-induced gut barrier breakdown.
Proc.Natl.Acad.Sci.USA, 116, 2019
8BGU
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BU of 8bgu by Molmil
human MDM2-5S RNP
Descriptor: 5S rRNA, 60S ribosomal protein L11, 60S ribosomal protein L5, ...
Authors:Castillo, N, Thoms, M, Flemming, D, Hammaren, H.M, Buschauer, R, Ameismeier, M, Bassler, J, Beck, M, Beckmann, R, Hurt, E.
Deposit date:2022-10-28
Release date:2023-06-14
Last modified:2023-08-30
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Structure of nascent 5S RNPs at the crossroad between ribosome assembly and MDM2-p53 pathways.
Nat.Struct.Mol.Biol., 30, 2023
5DTO
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BU of 5dto by Molmil
Dengue virus full length NS5 complexed with viral Cap 0-RNA and SAH
Descriptor: 7N-METHYL-8-HYDROGUANOSINE-5'-DIPHOSPHATE, ACETATE ION, MAGNESIUM ION, ...
Authors:Zhao, Y, Soh, T.S, Lim, S.P, Chung, K.Y, Swaminathan, K, Vasudevan, S.G, Shi, P.-Y, Lescar, J, Luo, D.
Deposit date:2015-09-18
Release date:2015-11-25
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.603 Å)
Cite:Molecular basis for specific viral RNA recognition and 2'-O-ribose methylation by the dengue virus nonstructural protein 5 (NS5)
Proc.Natl.Acad.Sci.USA, 112, 2015
6OWD
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BU of 6owd by Molmil
Arginine Containing Reengineered Coiled-Coiled Dimer to Examine the Impact of Proximal Cation Identity on Hydrophobically-Driven Assembly
Descriptor: CHLORIDE ION, R+7
Authors:Biok, N.A, Bingman, C.A, Gellman, S.H.
Deposit date:2019-05-09
Release date:2020-03-04
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Retention of Coiled-Coil Dimer Formation in the Absence of Ion Pairing at Positions Flanking the Hydrophobic Core.
Biochemistry, 58, 2019
5XEP
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BU of 5xep by Molmil
Crystal structure of BRP39, a chitinase-like protein, at 2.6 Angstorm resolution
Descriptor: 1,2-ETHANEDIOL, Chitinase-3-like protein 1
Authors:Mohanty, A.K, Fisher, A.J, Choudhary, S, Kaushik, J.K.
Deposit date:2017-04-05
Release date:2018-04-11
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal Structure of BRP39, a signalling glycoprotein expressed during mammary gland apoptosis.
To be published
8BX5
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BU of 8bx5 by Molmil
Alvinella pompejana nicotinic acetylcholine receptor Alpo4 in apo state (dataset 1)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Acetylcholine receptor
Authors:De Gieter, S, Efremov, R.G, Ulens, C.
Deposit date:2022-12-07
Release date:2023-07-12
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Sterol derivative binding to the orthosteric site causes conformational changes in an invertebrate Cys-loop receptor.
Elife, 12, 2023
5XDN
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BU of 5xdn by Molmil
Crystal structure of human voltage-dependent anion channel 1 (hVDAC1) in P22121 space group
Descriptor: DECANE, DODECANE, HEXANE, ...
Authors:Hosaka, T, Kimura-Someya, T, Shirouzu, M.
Deposit date:2017-03-28
Release date:2017-06-28
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:Crystal structural characterization reveals novel oligomeric interactions of human voltage-dependent anion channel 1
Protein Sci., 26, 2017
5X2R
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BU of 5x2r by Molmil
Direct Observation of Conformational Population Shifts in Hemoglobin: Crystal Structure of Half-Liganded Hemoglobin after Adding 10 mM phosphate pH 6.9.
Descriptor: Hemoglobin subunit alpha, Hemoglobin subunit beta, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Ohki, M, Park, S.-Y.
Deposit date:2017-02-02
Release date:2017-09-20
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Direct observation of conformational population shifts in crystalline human hemoglobin.
J. Biol. Chem., 292, 2017
5DUI
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BU of 5dui by Molmil
Identification of a new FoxO1 binding site that precludes CREB binding at the glucose-6-phosphatase catalytic subunit gene promoter
Descriptor: DNA (5'-D(*AP*TP*GP*AP*TP*TP*TP*AP*CP*GP*TP*AP*AP*AP*AP*TP*AP*GP*AP*AP*A)-3'), DNA (5'-D(*TP*TP*TP*TP*CP*TP*AP*TP*TP*TP*TP*AP*CP*GP*TP*AP*AP*AP*TP*CP*A)-3'), Forkhead box protein O1
Authors:Singh, P, Endrizzi, J.A, Chi, Y.-I.
Deposit date:2015-09-18
Release date:2016-09-21
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.306 Å)
Cite:Crystal structures reveal a new and novel FoxO1 binding site within the human glucose-6-phosphatase catalytic subunit 1 gene promoter.
J. Struct. Biol., 198, 2017
5XFY
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BU of 5xfy by Molmil
Crystal structure of a novel PET hydrolase S131A mutant from Ideonella sakaiensis 201-F6
Descriptor: GLYCEROL, Poly(ethylene terephthalate) hydrolase, SULFATE ION
Authors:Han, X, Liu, W.D, Zheng, Y.Y, Chen, C.C, Guo, R.T.
Deposit date:2017-04-11
Release date:2017-12-20
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structural insight into catalytic mechanism of PET hydrolase
Nat Commun, 8, 2017
5XG0
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BU of 5xg0 by Molmil
Crystal structure of a novel PET hydrolase from Ideonella sakaiensis 201-F6
Descriptor: Poly(ethylene terephthalate) hydrolase
Authors:Han, X, Liu, W.D, Zheng, Y.Y, Chen, C.C, Guo, R.T.
Deposit date:2017-04-11
Release date:2017-12-20
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:Structural insight into catalytic mechanism of PET hydrolase
Nat Commun, 8, 2017
8B7V
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BU of 8b7v by Molmil
Automated simulation-based refinement of maltoporin into a cryo-EM density
Descriptor: Maltoporin
Authors:Yvonnesdotter, L, Rovsnik, U, Blau, C, Lycksell, M, Howard, R.J, Lindahl, E.
Deposit date:2022-10-03
Release date:2023-06-21
Last modified:2023-07-26
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Automated simulation-based membrane protein refinement into cryo-EM data.
Biophys.J., 122, 2023
8BXD
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BU of 8bxd by Molmil
Alvinella pompejana nicotinic acetylcholine receptor Alpo4 in apo state (Alpo4_LMNG_Serotonin dataset 4)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Acetylcholine receptor
Authors:De Gieter, S, Efremov, R.G, Ulens, C.
Deposit date:2022-12-08
Release date:2023-07-12
Method:ELECTRON MICROSCOPY (6.2 Å)
Cite:Sterol derivative binding to the orthosteric site causes conformational changes in an invertebrate Cys-loop receptor.
Elife, 12, 2023
8BXF
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BU of 8bxf by Molmil
Alvinella pompejana nicotinic acetylcholine receptor Alpo4 in apo state (Alpo4_apo, dataset 1)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Acetylcholine receptor
Authors:De Gieter, S, Efremov, R.G, Ulens, C.
Deposit date:2022-12-08
Release date:2023-07-12
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Sterol derivative binding to the orthosteric site causes conformational changes in an invertebrate Cys-loop receptor.
Elife, 12, 2023
8BXB
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BU of 8bxb by Molmil
Alvinella pompejana nicotinic acetylcholine receptor Alpo in apo state (dataset 2)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Acetylcholine receptor
Authors:De Gieter, S, Efremov, R.G, Ulens, C.
Deposit date:2022-12-08
Release date:2023-07-12
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Sterol derivative binding to the orthosteric site causes conformational changes in an invertebrate Cys-loop receptor.
Elife, 12, 2023
8BXE
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BU of 8bxe by Molmil
Alvinella pompejana nicotinic acetylcholine receptor Alpo4 in apo state (Alpo4_comb dataset 3)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Acetylcholine receptor
Authors:De Gieter, S, Efremov, R.G, Ulens, C.
Deposit date:2022-12-08
Release date:2023-07-12
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Sterol derivative binding to the orthosteric site causes conformational changes in an invertebrate Cys-loop receptor.
Elife, 12, 2023
5E13
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BU of 5e13 by Molmil
Crystal structure of Eosinophil-derived neurotoxin in complex with the triazole double-headed ribonucleoside 11c
Descriptor: 3'-{4-[(4-amino-2-oxopyrimidin-1(2H)-yl)methyl]-1H-1,2,3-triazol-1-yl}-3'-deoxyadenosine, Non-secretory ribonuclease
Authors:Chatzileontiadou, D.S.M, Stravodimos, G.A, Kantsadi, A.L, Leonidas, D.D.
Deposit date:2015-09-29
Release date:2015-11-18
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.34 Å)
Cite:Triazole double-headed ribonucleosides as inhibitors of eosinophil derived neurotoxin.
Bioorg.Chem., 63, 2015
6OS0
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BU of 6os0 by Molmil
Structure of synthetic nanobody-stabilized angiotensin II type 1 receptor bound to angiotensin II
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensinogen, CHLORIDE ION, ...
Authors:Wingler, L.M, Staus, D.P, Skiba, M.A, McMahon, C, Kleinhenz, A.L.W, Lefkowitz, R.J, Kruse, A.C.
Deposit date:2019-05-01
Release date:2020-02-19
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Angiotensin and biased analogs induce structurally distinct active conformations within a GPCR.
Science, 367, 2020
5XD0
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BU of 5xd0 by Molmil
Apo Structure of Beta-1,3-1,4-glucanase from Paenibacillus sp.X4
Descriptor: DI(HYDROXYETHYL)ETHER, Glucanase, TRIETHYLENE GLYCOL
Authors:Baek, S.C, Ho, T.-H, Kang, L.-W, Kim, H.
Deposit date:2017-03-24
Release date:2017-04-19
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:Improvement of enzyme activity of beta-1,3-1,4-glucanase from Paenibacillus sp. X4 by error-prone PCR and structural insights of mutated residues.
Appl. Microbiol. Biotechnol., 101, 2017
5DW8
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BU of 5dw8 by Molmil
Crystal structure of 2'AMP bound SaIMPase-II
Descriptor: ADENOSINE-2'-MONOPHOSPHATE, CALCIUM ION, GLYCEROL, ...
Authors:Dutta, A, Bhattacharyya, S, Das, A.K.
Deposit date:2015-09-22
Release date:2015-12-09
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of 2'AMP bound SaIMPase-II
To Be Published
6OT3
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BU of 6ot3 by Molmil
RF2 accommodated state bound Release complex 70S at 24 ms
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Fu, Z, Indrisiunaite, G, Kaledhonkar, S, Shah, B, Sun, M, Chen, B, Grassucci, R.A, Ehrenberg, M, Frank, J.
Deposit date:2019-05-02
Release date:2019-06-19
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:The structural basis for release-factor activation during translation termination revealed by time-resolved cryogenic electron microscopy.
Nat Commun, 10, 2019
6OWI
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BU of 6owi by Molmil
Crystal structure of MYST acetyltransferase domain in complex with inhibitor 85
Descriptor: GLYCEROL, Histone acetyltransferase KAT8, N'-[(2-fluorophenyl)sulfonyl]benzohydrazide, ...
Authors:Hermans, S.J, Chung, M.C, Parker, M.W, Thomas, T, Baell, J.B.
Deposit date:2019-05-09
Release date:2020-04-01
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Discovery of Acylsulfonohydrazide-Derived Inhibitors of the Lysine Acetyltransferase, KAT6A, as Potent Senescence-Inducing Anti-Cancer Agents.
J.Med.Chem., 63, 2020
6OWM
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BU of 6owm by Molmil
Horse liver F93W alcohol dehydrogenase complexed with NAD and pentafluorobenzyl alcohol
Descriptor: (4R)-2-METHYLPENTANE-2,4-DIOL, 2,3,4,5,6-PENTAFLUOROBENZYL ALCOHOL, Alcohol dehydrogenase E chain, ...
Authors:Plapp, B.V.
Deposit date:2019-05-10
Release date:2019-05-22
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Substitutions of Amino Acid Residues in the Substrate Binding Site of Horse Liver Alcohol Dehydrogenase Have Small Effects on the Structures but Significantly Affect Catalysis of Hydrogen Transfer.
Biochemistry, 59, 2020

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數據於2024-07-31公開中

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