PDB: 35140 resultsInfo pagesStatus searchChemie searchBIRD

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5LSY	Structure of the Epigenetic Oncogene MMSET and inhibition by N-Alkyl Sinefungin Derivatives Descriptor: Histone-lysine N-methyltransferase SETD2, THIOCYANATE ION, ZINC ION, ... Authors: Tisi, D, Pathuri, P, Heightman, T. Deposit date: 2016-09-05 Release date: 2016-10-12 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.62 Å) Cite: Structure of the Epigenetic Oncogene MMSET and Inhibition by N-Alkyl Sinefungin Derivatives. ACS Chem. Biol., 11, 2016
5LT6	Structure of the Epigenetic Oncogene MMSET and inhibition by N-Alkyl Sinefungin Derivatives Descriptor: Histone-lysine N-methyltransferase SETD2, THIOCYANATE ION, ZINC ION, ... Authors: Tisi, D, Pathuri, P, Heightman, T. Deposit date: 2016-09-06 Release date: 2016-10-05 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (2.05 Å) Cite: Structure of the Epigenetic Oncogene MMSET and Inhibition by N-Alkyl Sinefungin Derivatives. ACS Chem. Biol., 11, 2016
2DUD	Crystal structure of human mitochondrial single-stranded DNA-binding protein(hmtSSB) Descriptor: Single-stranded DNA-binding protein Authors: Dong, X, Bessho, Y, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) Deposit date: 2006-07-21 Release date: 2007-01-21 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Crystal structure of human mitochondrial single-stranded DNA-binding protein(hmtSSB) To be Published
6ANV	Crystal structure of anti-CRISPR protein AcrF1 Descriptor: 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, DI(HYDROXYETHYL)ETHER, ... Authors: Yang, H, Patel, D.J. Deposit date: 2017-08-14 Release date: 2017-10-25 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.265 Å) Cite: Cryo-EM Structures Reveal Mechanism and Inhibition of DNA Targeting by a CRISPR-Cas Surveillance Complex. Cell, 171, 2017
8HCK	NMR fragment-based screening against the two PDZ do-mains of MDA-9 Descriptor: 4-BUTYL-1,2-DIPHENYL-PYRAZOLIDINE-3,5-DIONE, GLYCEROL, SULFATE ION, ... Authors: Tang, H. Deposit date: 2022-11-01 Release date: 2023-11-08 Method: X-RAY DIFFRACTION (2 Å) Cite: NMR fragment-based screening against the two PDZ do-mains of MDA-9 To Be Published
7E7Z	CryoEM structure of the human Kv4.2-KChIP1 complex, transmembrane region Descriptor: Potassium voltage-gated channel subfamily D member 2 Authors: Kise, Y, Nureki, O. Deposit date: 2021-02-28 Release date: 2021-10-06 Last modified: 2024-06-05 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: Structural basis of gating modulation of Kv4 channel complexes. Nature, 599, 2021
5LSS	Structure of the Epigenetic Oncogene MMSET and inhibition by N-Alkyl Sinefungin Derivatives Descriptor: Histone-lysine N-methyltransferase SETD2, THIOCYANATE ION, ZINC ION, ... Authors: Tisi, D, Pathuri, P. Deposit date: 2016-09-05 Release date: 2016-10-05 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (1.79 Å) Cite: Structure of the Epigenetic Oncogene MMSET and Inhibition by N-Alkyl Sinefungin Derivatives. ACS Chem. Biol., 11, 2016
8HGF	Human PKM2 mutant - C326S Descriptor: Pyruvate kinase PKM Authors: Chen, Y.-C, Lin, K.-T, Cheng, H.-C. Deposit date: 2022-11-14 Release date: 2023-11-15 Method: X-RAY DIFFRACTION (3.1 Å) Cite: Human PKM2 mutant - C326S To Be Published
7E87	CryoEM structure of the human Kv4.2-DPP6S complex, transmembrane and intracellular region Descriptor: Dipeptidyl aminopeptidase-like protein 6, Potassium voltage-gated channel subfamily D member 2 Authors: Kise, Y, Nureki, O. Deposit date: 2021-03-01 Release date: 2021-10-13 Last modified: 2024-06-05 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: Structural basis of gating modulation of Kv4 channel complexes. Nature, 599, 2021
4DCN	Crystal Structure Analysis of the Arfaptin2 BAR domain in Complex with ARL1 Descriptor: ADP-ribosylation factor-like protein 1, Arfaptin-2, MAGNESIUM ION, ... Authors: Nakamura, K, Xie, Y, Kawasaki, M, Kato, R, Wakatsuki, S. Deposit date: 2012-01-18 Release date: 2012-06-13 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (3.01 Å) Cite: Structural basis for membrane binding specificity of the Bin/Amphiphysin/Rvs (BAR) domain of Arfaptin-2 determined by Arl1 GTPase J.Biol.Chem., 287, 2012
7E8G	CryoEM structure of human Kv4.2-DPP6S-KChIP1 complex, extracellular region Descriptor: Dipeptidyl aminopeptidase-like protein 6 Authors: Kise, Y, Nureki, O. Deposit date: 2021-03-01 Release date: 2021-10-13 Last modified: 2022-02-16 Method: ELECTRON MICROSCOPY (4.5 Å) Cite: Structural basis of gating modulation of Kv4 channel complexes. Nature, 599, 2021
5ALB	Ticagrelor antidote candidate MEDI2452 in complex with ticagrelor Descriptor: MEDI2452 HEAVY CHAIN, MEDI2452 LIGHT CHAIN, Ticagrelor Authors: Buchanan, A, Newton, P, Pehrsson, S, Inghardt, T, Antonsson, T, Svensson, P, Sjogren, T, Oster, L, Janefeldt, A, Sandinge, A, Keyes, F, Austin, M, Spooner, J, Penney, M, Howells, G, Vaughan, T, Nylander, S. Deposit date: 2015-03-07 Release date: 2015-04-01 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.16 Å) Cite: Structural and Functional Characterisation of a Specific Antidote for Ticagrelor. Blood, 125, 2015
6J53	Crystal structure of human HINT1 complexing with ATP Descriptor: ADENOSINE MONOPHOSPHATE, Histidine triad nucleotide-binding protein 1 Authors: Wang, J, Fang, P, Guo, M. Deposit date: 2019-01-10 Release date: 2019-09-25 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (1.52 Å) Cite: Second messenger Ap4A polymerizes target protein HINT1 to transduce signals in Fc epsilon RI-activated mast cells. Nat Commun, 10, 2019
7E89	CryoEM structure of human Kv4.2-DPP6S complex, extracellular region Descriptor: Dipeptidyl aminopeptidase-like protein 6 Authors: Kise, Y, Nureki, O. Deposit date: 2021-03-01 Release date: 2021-10-13 Last modified: 2022-02-16 Method: ELECTRON MICROSCOPY (4 Å) Cite: Structural basis of gating modulation of Kv4 channel complexes. Nature, 599, 2021
6J58	Crystal structure of human HINT1 complexing with AP4A Descriptor: ADENOSINE MONOPHOSPHATE, Histidine triad nucleotide-binding protein 1 Authors: Wang, J, Fang, P, Guo, M. Deposit date: 2019-01-10 Release date: 2019-09-25 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (1.521 Å) Cite: Second messenger Ap4A polymerizes target protein HINT1 to transduce signals in Fc epsilon RI-activated mast cells. Nat Commun, 10, 2019
7ELG	LC3B modificated with a covalent probe Descriptor: 2-methylidene-5-thiophen-2-yl-cyclohexane-1,3-dione, Microtubule-associated proteins 1A/1B light chain 3B, SULFATE ION Authors: Fan, S, Wan, W. Deposit date: 2021-04-10 Release date: 2021-10-13 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.599 Å) Cite: Inhibition of Autophagy by a Small Molecule through Covalent Modification of the LC3 Protein. Angew.Chem.Int.Ed.Engl., 60, 2021
7E8B	CryoEM structure of human Kv4.2-DPP6S complex Descriptor: Dipeptidyl aminopeptidase-like protein 6, Potassium voltage-gated channel subfamily D member 2 Authors: Kise, Y, Nureki, O. Deposit date: 2021-03-01 Release date: 2021-10-13 Last modified: 2022-02-16 Method: ELECTRON MICROSCOPY (4.2 Å) Cite: Structural basis of gating modulation of Kv4 channel complexes. Nature, 599, 2021
6JCS	AAV5 in complex with AAVR Descriptor: Capsid protein, Dyslexia-associated protein KIAA0319-like protein Authors: Lou, Z, Zhang, R. Deposit date: 2019-01-30 Release date: 2019-08-14 Last modified: 2024-03-27 Method: ELECTRON MICROSCOPY (3.18 Å) Cite: Divergent engagements between adeno-associated viruses with their cellular receptor AAVR. Nat Commun, 10, 2019
8HKI	Human TRiC open state Descriptor: ADENOSINE-5'-DIPHOSPHATE, T-complex protein 1 subunit alpha, T-complex protein 1 subunit beta, ... Authors: Cong, Y, Liu, C.X. Deposit date: 2022-11-27 Release date: 2023-12-13 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: Pathway and mechanism of tubulin folding mediated by TRiC/CCT conjugated with its ATPase cycle revealed by cryo-EM To Be Published
6ANW	Crystal structure of anti-CRISPR protein AcrF10 Descriptor: anti-CRISPR protein AcrF10 Authors: Yang, H, Patel, D.J. Deposit date: 2017-08-14 Release date: 2017-10-25 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (2.486 Å) Cite: Cryo-EM Structures Reveal Mechanism and Inhibition of DNA Targeting by a CRISPR-Cas Surveillance Complex. Cell, 171, 2017
2MXF	Structure of the DNA complex of the C-Terminal domain of MvaT Descriptor: 5'-D(*CP*GP*CP*AP*TP*AP*TP*AP*TP*GP*CP*G)-3', MvaT Authors: Ding, P, Xia, B. Deposit date: 2014-12-30 Release date: 2015-07-01 Last modified: 2024-05-01 Method: SOLUTION NMR Cite: A Novel AT-Rich DNA Recognition Mechanism for Bacterial Xenogeneic Silencer MvaT. Plos Pathog., 11, 2015
2N26	Solution structure of Miz-1 zinc fingers 3 and 4 Descriptor: ZINC ION, Zinc finger and BTB domain-containing protein 17 Authors: Bedard, M, Lavigne, P. Deposit date: 2015-04-28 Release date: 2015-06-17 Last modified: 2024-05-01 Method: SOLUTION NMR Cite: Solution structure of the 13th C2H2 Zinc Finger of Miz-1. Biochem.Biophys.Res.Commun., 473, 2016
4DDP	crystal structure of Beclin 1 evolutionarily conserved domain(ECD) Descriptor: Beclin-1 Authors: Huang, W.J, Choi, W.Y, Wang, J.W, Shi, Y.G. Deposit date: 2012-01-19 Release date: 2012-02-22 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (1.547 Å) Cite: Crystal structure and biochemical analyses reveal Beclin 1 as a novel membrane binding protein Cell Res., 2012
5OK6	Ubiquitin specific protease 11 USP11 - peptide F complex Descriptor: 1,2-ETHANEDIOL, ALA-GLU-GLY-GLU-PHE-TYR-LYS-LEU-LYS-ILE-ARG-THR-PRO-AAR, GLYCEROL, ... Authors: Spiliotopoulos, A, Dreveny, I. Deposit date: 2017-07-25 Release date: 2018-08-08 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.3 Å) Cite: Discovery of peptide ligands targeting a specific ubiquitin-like domain-binding site in the deubiquitinase USP11. J.Biol.Chem., 294, 2019
2C9C	Structural basis of the nucleotide driven conformational changes in the AAA domain of transcription activator PspF Descriptor: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, PSP OPERON TRANSCRIPTIONAL ACTIVATOR Authors: Rappas, M, Schumacher, J, Niwa, H, Buck, M, Zhang, X. Deposit date: 2005-12-09 Release date: 2006-02-01 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Structural Basis of the Nucleotide Driven Conformational Changes in the Aaa(+) Domain of Transcription Activator Pspf. J.Mol.Biol., 357, 2006

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