7QL7
 
 | | Crystal structure of YTHDF1 YTH domain in complex with the ebsulfur derivative compound 9 | | Descriptor: | 1,2-ETHANEDIOL, THIOCYANATE ION, YTH domain-containing family protein 1, ... | | Authors: | Dalle Vedove, A, Cazzanelli, G, Quattrone, A, Provenzani, A, Lolli, G. | | Deposit date: | 2021-12-19 | | Release date: | 2022-11-23 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Small-Molecule Ebselen Binds to YTHDF Proteins Interfering with the Recognition of N 6 -Methyladenosine-Modified RNAs.
Acs Pharmacol Transl Sci, 5, 2022
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5VEG
 | | Structure of a Short-Chain Flavodoxin Associated with a Non-Canonical PDU Bacterial Microcompartment | | Descriptor: | CADMIUM ION, FLAVIN MONONUCLEOTIDE, Flavodoxin, ... | | Authors: | Sutter, M, Plegaria, J.S, Kerfeld, C.A. | | Deposit date: | 2017-04-04 | | Release date: | 2017-10-11 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (1.99 Å) | | Cite: | Structural and Functional Characterization of a Short-Chain Flavodoxin Associated with a Noncanonical 1,2-Propanediol Utilization Bacterial Microcompartment.
Biochemistry, 56, 2017
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2R8Y
 | | Crystal structure of YrbI phosphatase from Escherichia coli in a complex with Ca | | Descriptor: | CALCIUM ION, CHLORIDE ION, YrbI from Escherichia coli | | Authors: | Tsodikov, O.V, Aggarwal, P, Rubin, J.R, Stuckey, J.A, Woodard, R.W, Biswas, T. | | Deposit date: | 2007-09-11 | | Release date: | 2008-09-23 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | The Tail of KdsC: CONFORMATIONAL CHANGES CONTROL THE ACTIVITY OF A HALOACID DEHALOGENASE SUPERFAMILY PHOSPHATASE.
J.Biol.Chem., 284, 2009
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2R8E
 | | Crystal structure of YrbI from Escherichia coli in complex with Mg | | Descriptor: | 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, CHLORIDE ION, MAGNESIUM ION | | Authors: | Tsodikov, O.V, Aggarwal, P, Rubin, J.R, Stuckey, J.A, Woodard, R, Biswas, T. | | Deposit date: | 2007-09-10 | | Release date: | 2008-09-23 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | The Tail of KdsC: CONFORMATIONAL CHANGES CONTROL THE ACTIVITY OF A HALOACID DEHALOGENASE SUPERFAMILY PHOSPHATASE.
J.Biol.Chem., 284, 2009
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6EDC
 | | hcGAS-16bp dsDNA complex | | Descriptor: | Cyclic GMP-AMP synthase, DNA (5'-D(*AP*AP*AP*TP*TP*GP*CP*CP*GP*AP*AP*GP*AP*CP*GP*AP*A)-3'), DNA (5'-D(*TP*TP*CP*GP*TP*CP*TP*TP*CP*GP*GP*CP*AP*AP*T)-3'), ... | | Authors: | Xie, W, Lama, L, Adura, C, Glickman, J.F, Tuschl, T, Patel, D.J. | | Deposit date: | 2018-08-09 | | Release date: | 2019-05-29 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (2.712 Å) | | Cite: | Human cGAS catalytic domain has an additional DNA-binding interface that enhances enzymatic activity and liquid-phase condensation.
Proc.Natl.Acad.Sci.USA, 116, 2019
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4UPL
 | | Dimeric sulfatase SpAS2 from Silicibacter pomeroyi | | Descriptor: | SULFATASE FAMILY PROTEIN, ZINC ION | | Authors: | Jonas, S, van Loo, B, Hollfelder, F, Hyvonen, M. | | Deposit date: | 2014-06-17 | | Release date: | 2015-07-01 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (1.805 Å) | | Cite: | Balancing Specificity and Promiscuity in Enzyme Evolution: Multidimensional Activity Transitions in the Alkaline Phosphatase Superfamily.
J.Am.Chem.Soc., 141, 2019
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6EDB
 | | Crystal structure of SRY.hcGAS-21bp dsDNA complex | | Descriptor: | DNA (5'-D(*CP*GP*AP*TP*CP*CP*GP*GP*GP*AP*TP*CP*TP*AP*AP*AP*CP*AP*AP*TP*G)-3'), DNA (5'-D(*GP*CP*AP*TP*TP*GP*TP*TP*TP*AP*GP*AP*TP*CP*CP*CP*GP*GP*AP*TP*C)-3'), Sex-determining region Y protein,Cyclic GMP-AMP synthase, ... | | Authors: | Xie, W, Lama, L, Adura, C, Glickman, J.F, Tuschl, T, Patel, D.J. | | Deposit date: | 2018-08-09 | | Release date: | 2019-05-29 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (3.209 Å) | | Cite: | Human cGAS catalytic domain has an additional DNA-binding interface that enhances enzymatic activity and liquid-phase condensation.
Proc.Natl.Acad.Sci.USA, 116, 2019
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4UPK
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6AKJ
 | | The crystal structure of EMC complex | | Descriptor: | Enhancer of rudimentary homolog,YTH domain-containing protein mmi1 fusion protein, SULFATE ION | | Authors: | Li, F. | | Deposit date: | 2018-09-01 | | Release date: | 2019-02-13 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | A conserved dimer interface connects ERH and YTH family proteins to promote gene silencing.
Nat Commun, 10, 2019
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2MSO
 | | Solution study of cGm9a | | Descriptor: | Conotoxin Gm9.1 | | Authors: | Akcan, M, Clark, R.J, Daly, N.L, Conibear, A.C, de Faoite, A.C, Heghinian, M.C, Adams, D.J, Mari, F, Craik, D.J. | | Deposit date: | 2014-08-05 | | Release date: | 2015-07-22 | | Last modified: | 2023-12-27 | | Method: | SOLUTION NMR | | Cite: | Transforming conotoxins into cyclotides: Backbone cyclization of P-superfamily conotoxins.
Biopolymers, 104, 2015
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3CH8
 | | The crystal structure of PDZ-Fibronectin fusion protein | | Descriptor: | C-terminal octapeptide from protein ARVCF, MAGNESIUM ION, fusion protein PDZ-Fibronectin,Fibronectin | | Authors: | Makabe, K, Huang, J, Koide, A, Koide, S. | | Deposit date: | 2008-03-08 | | Release date: | 2009-03-31 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structural basis for exquisite specificity of affinity clamps, synthetic binding proteins generated through directed domain-interface evolution.
J.Mol.Biol., 392, 2009
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2OBG
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6MQO
 | | Structure of HIV-1 CA G208R | | Descriptor: | Capsid protein, IODIDE ION | | Authors: | Smaga, S.S, Xiong, Y. | | Deposit date: | 2018-10-10 | | Release date: | 2019-06-19 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | MxB Restricts HIV-1 by Targeting the Tri-hexamer Interface of the Viral Capsid.
Structure, 27, 2019
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2P49
 | | Complex of a camelid single-domain vhh antibody fragment with RNASE A at 1.4A resolution: native mono_1 crystal form | | Descriptor: | ANTIBODY CAB-RN05, PHOSPHATE ION, Ribonuclease pancreatic | | Authors: | Tereshko, V, Uysal, S, Margalef, K, Koide, A, Kossiakoff, A.A, Koide, S. | | Deposit date: | 2007-03-11 | | Release date: | 2007-08-28 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.38 Å) | | Cite: | Exploring the capacity of minimalist protein interfaces: interface energetics and affinity maturation to picomolar KD of a single-domain antibody with a flat paratope.
J.Mol.Biol., 373, 2007
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7BQI
 | | Crystal structure of FYCO1 RUN domain | | Descriptor: | FYVE and coiled-coil domain-containing protein 1 | | Authors: | Sakurai, S, Shimizu, T, Ohto, U. | | Deposit date: | 2020-03-24 | | Release date: | 2020-08-05 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (1.3 Å) | | Cite: | Crystal structure of the FYCO1 RUN domain suggests possible interfaces with small GTPases.
Acta Crystallogr.,Sect.F, 76, 2020
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2P4A
 | | X-ray structure of a camelid affinity matured single-domain vhh antibody fragment in complex with RNASE A | | Descriptor: | ANTIBODY CAB-RN05, Ribonuclease pancreatic, SULFATE ION | | Authors: | Tereshko, V, Koide, A, Uysal, S, Koide, S. | | Deposit date: | 2007-03-11 | | Release date: | 2007-08-28 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Exploring the capacity of minimalist protein interfaces: interface energetics and affinity maturation to picomolar KD of a single-domain antibody with a flat paratope.
J.Mol.Biol., 373, 2007
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6NDZ
 | | Designed repeat protein in complex with Fz8 | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, ACETATE ION, ACETIC ACID, ... | | Authors: | Miao, Y, Jude, K.M, Garcia, K.C. | | Deposit date: | 2018-12-14 | | Release date: | 2019-05-15 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (2.264 Å) | | Cite: | Receptor subtype discrimination using extensive shape complementary designed interfaces.
Nat.Struct.Mol.Biol., 26, 2019
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6NE2
 | | Designed repeat protein in complex with Fz7 | | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, ... | | Authors: | Miao, Y, Jude, K.M, Garcia, K.C. | | Deposit date: | 2018-12-15 | | Release date: | 2019-05-15 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (1.299 Å) | | Cite: | Receptor subtype discrimination using extensive shape complementary designed interfaces.
Nat.Struct.Mol.Biol., 26, 2019
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6NE1
 | | Designed repeat protein in complex with Fz4 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Frizzled-4, Pfs, ... | | Authors: | Miao, Y, Jude, K.M, Garcia, K.C. | | Deposit date: | 2018-12-15 | | Release date: | 2019-05-15 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (3.011 Å) | | Cite: | Receptor subtype discrimination using extensive shape complementary designed interfaces.
Nat.Struct.Mol.Biol., 26, 2019
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6NE4
 | | Designed repeat protein specifically in complex with Fz7CRD | | Descriptor: | 1,2-ETHANEDIOL, Designed repeat binding protein, Frizzled-7, ... | | Authors: | Miao, Y, Jude, K.M, Garcia, K.C. | | Deposit date: | 2018-12-16 | | Release date: | 2019-05-15 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (1.648 Å) | | Cite: | Receptor subtype discrimination using extensive shape complementary designed interfaces.
Nat.Struct.Mol.Biol., 26, 2019
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6MQA
 | | Structure of HIV-1 CA P207S | | Descriptor: | CHLORIDE ION, Capsid protein, IODIDE ION | | Authors: | Smaga, S.S, Xiong, Y. | | Deposit date: | 2018-10-09 | | Release date: | 2019-06-19 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (3.199 Å) | | Cite: | MxB Restricts HIV-1 by Targeting the Tri-hexamer Interface of the Viral Capsid.
Structure, 27, 2019
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6MQP
 | | Structure of HIV-1 CA T210K | | Descriptor: | CHLORIDE ION, Capsid protein, IODIDE ION | | Authors: | Smaga, S.S, Xiong, Y. | | Deposit date: | 2018-10-10 | | Release date: | 2019-06-19 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (3.296 Å) | | Cite: | MxB Restricts HIV-1 by Targeting the Tri-hexamer Interface of the Viral Capsid.
Structure, 27, 2019
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2R8Z
 | | Crystal structure of YrbI phosphatase from Escherichia coli in complex with a phosphate and a calcium ion | | Descriptor: | 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, CALCIUM ION, PHOSPHATE ION | | Authors: | Tsodikov, O.V, Aggarwal, P, Rubin, J.R, Stuckey, J.A, Woodard, R.W, Biswas, T. | | Deposit date: | 2007-09-11 | | Release date: | 2008-09-23 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | The Tail of KdsC: CONFORMATIONAL CHANGES CONTROL THE ACTIVITY OF A HALOACID DEHALOGENASE SUPERFAMILY PHOSPHATASE.
J.Biol.Chem., 284, 2009
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2MSQ
 | | Solution study of cBru9a | | Descriptor: | Conotoxin cBru9a | | Authors: | Akcan, M, Clark, R.J, Daly, N.L, Conibear, A.C, de Faoite, A.C, Heghinian, M.C, Adams, D.J, Mari, F, Craik, D.J. | | Deposit date: | 2014-08-05 | | Release date: | 2015-07-22 | | Last modified: | 2023-06-14 | | Method: | SOLUTION NMR | | Cite: | Transforming conotoxins into cyclotides: Backbone cyclization of P-superfamily conotoxins.
Biopolymers, 104, 2015
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2QDN
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